Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101054052
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Entry
101054052 CDS
T04350
Gene name
RAF1
Definition
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase isoform X2
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
sbq
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq01521
EGFR tyrosine kinase inhibitor resistance
sbq01522
Endocrine resistance
sbq04010
MAPK signaling pathway
sbq04012
ErbB signaling pathway
sbq04014
Ras signaling pathway
sbq04015
Rap1 signaling pathway
sbq04022
cGMP-PKG signaling pathway
sbq04024
cAMP signaling pathway
sbq04062
Chemokine signaling pathway
sbq04068
FoxO signaling pathway
sbq04071
Sphingolipid signaling pathway
sbq04072
Phospholipase D signaling pathway
sbq04140
Autophagy - animal
sbq04150
mTOR signaling pathway
sbq04151
PI3K-Akt signaling pathway
sbq04210
Apoptosis
sbq04218
Cellular senescence
sbq04270
Vascular smooth muscle contraction
sbq04360
Axon guidance
sbq04370
VEGF signaling pathway
sbq04371
Apelin signaling pathway
sbq04510
Focal adhesion
sbq04540
Gap junction
sbq04550
Signaling pathways regulating pluripotency of stem cells
sbq04613
Neutrophil extracellular trap formation
sbq04625
C-type lectin receptor signaling pathway
sbq04630
JAK-STAT signaling pathway
sbq04650
Natural killer cell mediated cytotoxicity
sbq04660
T cell receptor signaling pathway
sbq04662
B cell receptor signaling pathway
sbq04664
Fc epsilon RI signaling pathway
sbq04666
Fc gamma R-mediated phagocytosis
sbq04720
Long-term potentiation
sbq04722
Neurotrophin signaling pathway
sbq04726
Serotonergic synapse
sbq04730
Long-term depression
sbq04810
Regulation of actin cytoskeleton
sbq04910
Insulin signaling pathway
sbq04912
GnRH signaling pathway
sbq04914
Progesterone-mediated oocyte maturation
sbq04915
Estrogen signaling pathway
sbq04916
Melanogenesis
sbq04917
Prolactin signaling pathway
sbq04919
Thyroid hormone signaling pathway
sbq04921
Oxytocin signaling pathway
sbq04926
Relaxin signaling pathway
sbq04928
Parathyroid hormone synthesis, secretion and action
sbq04929
GnRH secretion
sbq04935
Growth hormone synthesis, secretion and action
sbq05010
Alzheimer disease
sbq05022
Pathways of neurodegeneration - multiple diseases
sbq05034
Alcoholism
sbq05132
Salmonella infection
sbq05152
Tuberculosis
sbq05160
Hepatitis C
sbq05161
Hepatitis B
sbq05163
Human cytomegalovirus infection
sbq05164
Influenza A
sbq05165
Human papillomavirus infection
sbq05167
Kaposi sarcoma-associated herpesvirus infection
sbq05170
Human immunodeficiency virus 1 infection
sbq05200
Pathways in cancer
sbq05205
Proteoglycans in cancer
sbq05206
MicroRNAs in cancer
sbq05210
Colorectal cancer
sbq05211
Renal cell carcinoma
sbq05212
Pancreatic cancer
sbq05213
Endometrial cancer
sbq05214
Glioma
sbq05215
Prostate cancer
sbq05218
Melanoma
sbq05219
Bladder cancer
sbq05220
Chronic myeloid leukemia
sbq05221
Acute myeloid leukemia
sbq05223
Non-small cell lung cancer
sbq05224
Breast cancer
sbq05225
Hepatocellular carcinoma
sbq05226
Gastric cancer
sbq05230
Central carbon metabolism in cancer
sbq05231
Choline metabolism in cancer
sbq05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
sbq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101054052 (RAF1)
04012 ErbB signaling pathway
101054052 (RAF1)
04014 Ras signaling pathway
101054052 (RAF1)
04015 Rap1 signaling pathway
101054052 (RAF1)
04370 VEGF signaling pathway
101054052 (RAF1)
04371 Apelin signaling pathway
101054052 (RAF1)
04630 JAK-STAT signaling pathway
101054052 (RAF1)
04068 FoxO signaling pathway
101054052 (RAF1)
04072 Phospholipase D signaling pathway
101054052 (RAF1)
04071 Sphingolipid signaling pathway
101054052 (RAF1)
04024 cAMP signaling pathway
101054052 (RAF1)
04022 cGMP-PKG signaling pathway
101054052 (RAF1)
04151 PI3K-Akt signaling pathway
101054052 (RAF1)
04150 mTOR signaling pathway
101054052 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101054052 (RAF1)
09143 Cell growth and death
04210 Apoptosis
101054052 (RAF1)
04218 Cellular senescence
101054052 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101054052 (RAF1)
04540 Gap junction
101054052 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
101054052 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101054052 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
101054052 (RAF1)
04625 C-type lectin receptor signaling pathway
101054052 (RAF1)
04650 Natural killer cell mediated cytotoxicity
101054052 (RAF1)
04660 T cell receptor signaling pathway
101054052 (RAF1)
04662 B cell receptor signaling pathway
101054052 (RAF1)
04664 Fc epsilon RI signaling pathway
101054052 (RAF1)
04666 Fc gamma R-mediated phagocytosis
101054052 (RAF1)
04062 Chemokine signaling pathway
101054052 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
101054052 (RAF1)
04929 GnRH secretion
101054052 (RAF1)
04912 GnRH signaling pathway
101054052 (RAF1)
04915 Estrogen signaling pathway
101054052 (RAF1)
04914 Progesterone-mediated oocyte maturation
101054052 (RAF1)
04917 Prolactin signaling pathway
101054052 (RAF1)
04921 Oxytocin signaling pathway
101054052 (RAF1)
04926 Relaxin signaling pathway
101054052 (RAF1)
04935 Growth hormone synthesis, secretion and action
101054052 (RAF1)
04919 Thyroid hormone signaling pathway
101054052 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
101054052 (RAF1)
04916 Melanogenesis
101054052 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
101054052 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
101054052 (RAF1)
04720 Long-term potentiation
101054052 (RAF1)
04730 Long-term depression
101054052 (RAF1)
04722 Neurotrophin signaling pathway
101054052 (RAF1)
09158 Development and regeneration
04360 Axon guidance
101054052 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101054052 (RAF1)
05206 MicroRNAs in cancer
101054052 (RAF1)
05205 Proteoglycans in cancer
101054052 (RAF1)
05230 Central carbon metabolism in cancer
101054052 (RAF1)
05231 Choline metabolism in cancer
101054052 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101054052 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
101054052 (RAF1)
05212 Pancreatic cancer
101054052 (RAF1)
05225 Hepatocellular carcinoma
101054052 (RAF1)
05226 Gastric cancer
101054052 (RAF1)
05214 Glioma
101054052 (RAF1)
05221 Acute myeloid leukemia
101054052 (RAF1)
05220 Chronic myeloid leukemia
101054052 (RAF1)
05218 Melanoma
101054052 (RAF1)
05211 Renal cell carcinoma
101054052 (RAF1)
05219 Bladder cancer
101054052 (RAF1)
05215 Prostate cancer
101054052 (RAF1)
05213 Endometrial cancer
101054052 (RAF1)
05224 Breast cancer
101054052 (RAF1)
05223 Non-small cell lung cancer
101054052 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
101054052 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
101054052 (RAF1)
09165 Substance dependence
05034 Alcoholism
101054052 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
101054052 (RAF1)
05152 Tuberculosis
101054052 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101054052 (RAF1)
05161 Hepatitis B
101054052 (RAF1)
05160 Hepatitis C
101054052 (RAF1)
05164 Influenza A
101054052 (RAF1)
05163 Human cytomegalovirus infection
101054052 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
101054052 (RAF1)
05165 Human papillomavirus infection
101054052 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101054052 (RAF1)
01522 Endocrine resistance
101054052 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sbq01001
]
101054052 (RAF1)
Enzymes [BR:
sbq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101054052 (RAF1)
Protein kinases [BR:
sbq01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
101054052 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
101054052
NCBI-ProteinID:
XP_003927092
UniProt:
A0A2K6S6V4
LinkDB
All DBs
Position
Unknown
AA seq
648 aa
AA seq
DB search
MEHIQGAWKTISNGFGLKDAVFDGSSCISPTLVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVTRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNL
SPTGWSQPKTPLPAQRERAPGSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSF
GTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIV
TQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGL
TVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYE
LMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFP
QILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaatggttttggactcaaagatgct
gtgtttgatggctccagctgcatctctcctacactagttcagcagtttggctatcagcgc
cgggcatcagatgatggcaaactcacagatccttcgaagacaagcaacactatccgtgtt
ttcttgccgaacaagcaaagaacagtggtcaatgtgagaaatggaatgagcttgcatgac
tgccttatgaaagcgctgaaggtgaggggcctgcaaccagagtgctgtgcagtgttcaga
cttctccaagaacataaaggtaaaaaagcacgcttagattggaatactgatgctgcctct
ttgattggagaagaacttcaagtagatttcctggatcatgttcccctcacaacacacaac
tttgctcggaagacgttcctgaagcttgccttctgtgacatctgtcagaaattcctgctc
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgtttccaaattccact
attggtgatagtggagtcccagcactaccttctttgactatgcgtcgtatgcgagagtct
gttacccggatgcctgttagttctcagcacagatattctacacctcacgccttcaccttt
aacacctccagtccctcatctgaaggttccctctcccagaggcagaggtcgacgtctaca
cctaatgtccatatggtcagcaccaccctgcctgtggacagcaggatgattgaggatgca
attcgaagtcacagcgaatcagcctcaccttcagccctgtccagtagccccaacaatctg
agcccaacaggctggtcacagcccaaaacccccttgccagcacaaagggagcgggcacca
ggatctggaacccaggagaaaaacaaaattagacctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctctttt
ggaactgtttataagggcaaatggcatggagatgttgcagtaaagatcctaaaggttgtc
gacccaaccccagagcagttccaggccttcaggaatgaggtggctgttttgcgcaaaaca
cggcatgtgaacattctgcttttcatggggtacatgacaaaggacaacctggcaattgtg
acccagtggtgcgagggcagcagcctttacaaacacctgcatgtccaggagaccaagttt
cagatgttccagctaattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggccta
acagtgaaaattggagattttggtttggcaacagtaaagtcacgctggagtggttctcag
caggttgaacaacctactggctctgttctgtggatggctccagaggtgatccgaatgcag
gataacaacccattcagcttccagtcagatgtctactcctatggcatcgtattatatgag
ctgatgacaggggagcttccttactctcacattaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagatcttagtaagctatataagaactgccccaaagca
atgaagaggctggtagctgactgtgtcaagaaagtaaaggaagagaggcctctttttccc
cagattctgtcttccattgagctgctccagcactctctaccgaagatcaaccggagcgct
tccgagccatccttgcatcgggcagcccacactgaggatatcaatgcttgcacgctgacc
acatccccgaggctgcctgtcttctag
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integrated database retrieval system
