Streptomyces collinus: B446_20930
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Entry
B446_20930 CDS
T02787
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
sci
Streptomyces collinus
Pathway
sci00290
Valine, leucine and isoleucine biosynthesis
sci00770
Pantothenate and CoA biosynthesis
sci01100
Metabolic pathways
sci01110
Biosynthesis of secondary metabolites
sci01210
2-Oxocarboxylic acid metabolism
sci01230
Biosynthesis of amino acids
Module
sci_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
sci_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
sci00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
B446_20930
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
B446_20930
Enzymes [BR:
sci01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
B446_20930
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Paralog
Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD
DUF4154
Motif
Other DBs
NCBI-ProteinID:
AGS70998
UniProt:
S5UV02
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Position
4834375..4836228
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AA seq
617 aa
AA seq
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MPELRSRTVTHGRNMAGARALMRASGVPGADIGRKPVIAVANSFTEFVPGHTHLQPVGRI
VSEAIKEAGGIPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALVCI
SNCDKITPGMLMAALRLNIPTVFVSGGPMESGRATLVDGTVRTLDLVDAISDAVNDKISD
EDILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARRALYENAART
VMDLTRRYYEQDDDTVLPLNIATFQAFENAMALDIAMGGSTNTILHLLAAAQEAGVAFGL
EEIDAVSRRVPCLAKVAPNVAKNRTYYMEDVHRAGGIPALLGELHRAGLLNEDVHAVHSP
SLSDWLKTWDVRGGSPSPEAVELWHAAPGCVRSAEAFSQSERWEALDDDAEGGCIRSAEH
AYSKDGGLAVLRGNLAVDGCVVKTAGVDESIWTFEGPAVVCESQEEAVQRILTQEVKDGD
VVVIRYEGPKGGPGMQEMLYPTSYLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAAS
GGTIALVRDGDRIRIDIPNRAIELLVDEAELNRREEALGGVYAPRDRDRKVSAALRAYAA
MATSADKGAVRDVSRLG
NT seq
1854 nt
NT seq
+upstream
nt +downstream
nt
atgcccgagctgaggtcccgcacagtcacccacggccgcaacatggcgggcgcccgcgcc
cttatgcgcgcctccggtgtacccggtgcggacatcggccggaagcccgtcatcgccgtc
gccaactccttcaccgagttcgtgccgggccacacccacctccagccggtcggccggatc
gtcagcgaggcgatcaaggaggcgggcggcatcccccgcgagttcaacacgatcgccgtg
gacgacggcatcgcgatgggccacggcggcatgctgtactccctgccctcccgcgacctg
atcgccgactcggtcgagtacatggtcgaggcgcactgcgccgacgccctggtctgcatc
tccaactgcgacaagatcaccccgggcatgctgatggcggccctgcgcctgaacatcccg
acggtcttcgtctccggcggccccatggagtccggccgggccaccctcgtcgacggcacg
gtccgcaccctcgacctggtcgacgcgatctccgacgccgtcaacgacaagatctccgac
gaggacatcctccgcatcgaggagaacgcctgccccacctgcggcagctgttccggcatg
ttcaccgccaactcgatgaactgcctcaccgaggccatcggcctctccctgcccggcaac
ggctcggtcctcgccacccacaccgcccgccgcgccctgtacgagaacgcggcccgcacg
gtcatggacctcacccgccgctactacgagcaggacgacgacaccgtcctgccgctcaac
atcgccaccttccaggccttcgagaacgccatggccctggacatcgcgatgggcggctcc
accaacacgatcctgcacctgctggccgccgcccaggaggcgggcgtcgccttcggcctg
gaggagatcgacgccgtctcccgccgcgtcccctgcctcgccaaggtcgcccccaacgtc
gcgaagaaccgcacgtactacatggaggacgtgcaccgggccggcggcatccccgccctg
ctcggcgagctgcaccgcgcgggcctgctcaacgaggacgtgcacgcggtccacagcccc
tccctctccgactggctcaagacctgggacgtccgcggcggctccccgtcccccgaggcc
gtcgagctgtggcacgcggcccccggctgcgtccgctccgccgaggccttctcccagtcc
gagcgctgggaggcgctggacgacgacgccgagggcggctgcatccgcagcgccgagcac
gcctactccaaggacggcggcctcgccgtcctgagggggaacctggccgtcgacggctgc
gtggtcaagacggccggcgtcgacgagtcgatctggaccttcgagggcccggccgtggtc
tgcgagtcccaggaggaggccgtccagcggatcctcacccaggaggtcaaggacggcgac
gtcgtcgtcatccgctacgagggccccaagggcggacccggcatgcaggagatgctctac
ccgacctcgtacctgaagggccgcggcctgggcaagacctgcgccctgatcaccgacggc
cgcttctccggcggcacctccggcctctccatcggccacgcctcccccgaggcggcctcc
ggcggcaccatcgccctggtccgggacggcgaccgcatccgcatcgacatccccaaccgc
gcgatcgagctgctggtcgacgaggcggaactgaaccgccgcgaagaggccctcggcggc
gtgtacgccccgcgcgaccgcgaccgcaaggtctccgccgcgctgcgtgcctacgcggcg
atggcgaccagcgcggacaagggcgcggtgcgcgacgtgagccgactgggctga
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