Streptomyces coelicolor: SCO2050
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Entry
SCO2050 CDS
T00085
Symbol
hisA, SC4G6.19c
Name
(RefSeq) 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase
KO
K24017
phosphoribosyl isomerase A [EC:
5.3.1.16
5.3.1.24
]
Organism
sco
Streptomyces coelicolor
Pathway
sco00340
Histidine metabolism
sco00400
Phenylalanine, tyrosine and tryptophan biosynthesis
sco01100
Metabolic pathways
sco01110
Biosynthesis of secondary metabolites
sco01230
Biosynthesis of amino acids
Module
sco_M00023
Tryptophan biosynthesis, chorismate => tryptophan
sco_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
sco00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
SCO2050 (hisA)
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
SCO2050 (hisA)
Enzymes [BR:
sco01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.1 Interconverting aldoses and ketoses, and related compounds
5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
SCO2050 (hisA)
5.3.1.24 phosphoribosylanthranilate isomerase
SCO2050 (hisA)
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Gene cluster
GFIT
Motif
Pfam:
His_biosynth
NMO
Dus
IMPDH
TMP-TENI
BAT
RP1-2
Motif
Other DBs
NCBI-GeneID:
1097484
Kitasato:
SCO2050
LinkDB
All DBs
Position
complement(2197966..2198688)
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AA seq
240 aa
AA seq
DB search
MSKLELLPAVDVRDGQAVRLVHGESGTETSYGSPLEAALAWQRSGAEWLHLVDLDAAFGT
GDNRALIAEVAQAMDIKVELSGGIRDDDTLAAALATGCTRVNLGTAALETPEWVAKVIAE
HGDKIAVGLDVRGTTLRGRGWTRDGGDLYETLDRLNKEGCARYVVTDIAKDGTLQGPNLE
LLKNVCAATDRPVVASGGVSSLDDLRAIAGLVPAGVEGAIVGKALYAKAFTLEEALEATS
NT seq
723 nt
NT seq
+upstream
nt +downstream
nt
atgagcaagctcgaactcctccccgccgtcgacgtccgcgacggccaggccgtccgcctc
gtgcacggcgagtccggcaccgagacctcctacggctccccgctggaggccgccctcgcc
tggcagcgctccggcgccgagtggctgcacctggtggacctggacgcggcgttcgggacc
ggggacaaccgcgcgctgatcgccgaggtcgcgcaggccatggacatcaaggtggagctg
tccggcggcatccgcgacgacgacaccctcgccgccgcgctcgccaccggctgtacccgg
gtgaacctgggcacggccgccctggagacccccgagtgggtcgccaaggtcatcgccgag
cacggcgacaagatcgcggtcggcctggacgtacggggcaccacgctccgcggccgcggc
tggacccgcgacggcggcgacctctacgagacgctggaccgcctgaacaaggagggctgc
gcccgctacgtcgtcaccgacatcgccaaggacggcaccctccagggccccaacctggag
ctgctgaagaacgtctgcgcggccaccgaccgcccggtcgtggcgtcgggcggcgtctcc
tccctggacgacctgcgcgcgatcgccgggctcgtcccggccggtgtcgagggggccatc
gtcgggaaggccctgtacgcgaaggcgttcaccctggaagaagccttggaggctacgtcg
tga
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