Streptomyces cyaneochromogenes: EJ357_05040
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Entry
EJ357_05040 CDS
T06811
Name
(GenBank) NADP-dependent isocitrate dehydrogenase
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
scya
Streptomyces cyaneochromogenes
Pathway
scya00020
Citrate cycle (TCA cycle)
scya00480
Glutathione metabolism
scya01100
Metabolic pathways
scya01110
Biosynthesis of secondary metabolites
scya01120
Microbial metabolism in diverse environments
scya01200
Carbon metabolism
scya01210
2-Oxocarboxylic acid metabolism
scya01230
Biosynthesis of amino acids
Module
scya_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scya_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
scya00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
EJ357_05040
09106 Metabolism of other amino acids
00480 Glutathione metabolism
EJ357_05040
Enzymes [BR:
scya01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
EJ357_05040
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GFIT
Motif
Pfam:
IDH
Pr_beta_C
Motif
Other DBs
NCBI-ProteinID:
AZQ32892
UniProt:
A0A3Q9ELD6
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All DBs
Position
1180504..1182723
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AA seq
739 aa
AA seq
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MTDSTIIYTHTDEAPALATYSFLPVVQAYASQAGVAVETRDISLAGRIIAVFPEYLTEDQ
RIPDALHELGELAKTPAANIIKLPNISASIPQLKAAVAELQGQGYALPNYPDDPKTDEER
EIQARYDKVKGSAVNPVLREGNSDRRAPASVKNYAKTHPHRMGAWTSESKTNVATMGEND
FRSTEKSVVISEAGSLRIELVAEDGTTTVLRESVPVLKDEVVDASVMRVAALREFLTAQV
ARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPKTFEKYGETLAAAGLSPNDGLGGI
LKGLDALPNGAEIKASFDAEIAEGPALAMVDSDKGITNLHVPSDVIVDASMPAMIRTSGH
MWGPDGQEADTLAVLPDSSYSGVYQAVLDDCRANGAYDPSTMGSVPNVGLMAQKAEEYGS
HDKTFEIKAAGTVRLVDQAGNVVIEQPVAEGDIFRACQTKDAPIKDWVKLAVTRARATGD
PAVFWLDETRAHDANLIAKVNAYLPEHDTEGLDIRILAPVEATKLSVERIRRGENTISVT
GNVLRDYLTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQLVKENYLRWD
SLGEFFALVPSLEQYATATGNTRAKVLADTLDRATATFLNEDKSPTRRVGGIDNRGSHFF
LSLYWAQELAKQTDDADLAKAFAPLAETLTASEQKIVDELNAVQGKPAEIGGYYQPDPAK
AAAVMRPSATWNEALASLS
NT seq
2220 nt
NT seq
+upstream
nt +downstream
nt
gtgactgactcgaccatcatctatacgcacactgacgaggccccggccctggcgacgtat
tccttcctgccggtggtccaggcgtacgcctcgcaggcgggtgtcgccgtggagacgcgg
gacatctcgctggccggccgcatcatcgcggtgttcccggagtacctgaccgaggaccag
cgcatcccggacgccctgcacgagctgggcgagctggccaagacgccggcggccaacatc
atcaagctgccgaacatctcggcgtcgatcccgcagctcaaggccgccgtcgccgagctc
cagggccagggctacgcgctgccgaactacccggacgacccgaagaccgacgaggagcgg
gagatccaggcccgctacgacaaggtcaagggctccgccgtgaacccggtcctgcgtgag
ggcaactccgaccgccgcgcccccgcctcggtcaagaactacgccaagacccacccgcac
cgcatgggcgcctggacctccgagtccaagacgaacgtggcgaccatgggcgagaacgac
ttccgctccaccgagaagtccgtcgtgatctccgaggcgggttcgctccggatcgagctg
gtcgccgaggacggcaccaccaccgtcctgcgcgagtccgtaccggtcctcaaggacgag
gtcgtcgacgcctccgtgatgcgggtcgccgcgctgcgcgagttcctgaccgcgcaggtc
gcccgggccaaggccgagggcgtgctgttctccgtgcacctcaaggccacgatgatgaag
gtctccgacccgatcatcttcggtcacgtggtgcgcgccttcttcccgaagaccttcgag
aagtacggcgagacgctcgccgccgccggcctgtcccccaacgacggtctgggcggcatc
ctcaagggcctggacgcgctgccgaacggcgccgagatcaaggcgtccttcgacgcggag
atcgccgagggcccggcgctggccatggtcgactccgacaagggcatcaccaacctgcac
gtgccgtccgacgtgatcgtcgacgcctcgatgccggccatgatccgcacctccggccac
atgtggggcccggacggccaggaggccgacaccctcgcggtgctcccggactcctcctac
tccggcgtctaccaggccgtgctcgacgactgccgtgccaacggcgcctacgacccgtcg
accatgggctcggtcccgaacgtcggcctgatggcgcagaaggccgaggagtacggctcc
cacgacaagaccttcgagatcaaggccgccggcacggtccggctggtcgaccaggccggc
aacgtggtcatcgagcagccggtcgccgagggtgacatcttccgcgcctgccagaccaag
gacgcgccgatcaaggactgggtgaagctggccgtcacccgcgcccgcgccaccggcgac
ccggccgtcttctggctggacgagacccgcgcgcacgacgccaacctgatcgccaaggtc
aacgcctacctgccggagcacgacaccgagggtctggacatccgcatcctcgccccggtc
gaggccaccaagctgtcggtggagcgcatccgccgcggcgagaacacgatctcggtgacg
ggcaacgtcctgcgcgactacctcaccgacctgttcccgatcctggagctgggcaccagc
gccaagatgctgtcggtcgtcccgctgatggcgggcggcggcctgttcgagacgggcgcc
ggcggcagcgcgccgaagcacgtccagcagctggtcaaggagaactacctgcgctgggac
tccctcggtgagttcttcgcgctcgttccctccctggagcagtacgcgaccgctaccggc
aacacccgcgcgaaggtcctcgcggacacgctggaccgcgccacggcgaccttcctcaac
gaggacaagtccccgacccgtcgcgtcggcggcatcgacaaccgcggcagccacttcttc
ctgtccctgtactgggcgcaggagctggccaagcagaccgacgacgcggacctggccaag
gccttcgccccgctcgccgagacgctcaccgcgagcgagcagaagatcgtcgacgagctg
aacgccgtccagggcaagccggccgagatcggcggctactaccagcccgacccggccaag
gccgccgcggtcatgcgcccgtcggccacctggaacgaggcgctcgcgtccctgagctga
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