Streptomyces pratensis: Sfla_3937
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Entry
Sfla_3937 CDS
T01647
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sfa
Streptomyces pratensis
Pathway
sfa00860
Porphyrin metabolism
sfa01100
Metabolic pathways
sfa01110
Biosynthesis of secondary metabolites
sfa01120
Microbial metabolism in diverse environments
sfa01240
Biosynthesis of cofactors
Module
sfa_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sfa_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sfa_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sfa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Sfla_3937
Enzymes [BR:
sfa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Sfla_3937
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
ADW05353
UniProt:
A0A8D3WHU7
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All DBs
Position
4554259..4555416
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AA seq
385 aa
AA seq
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MHDDDAQHGPLAGFTVGVTAARRAEELGTLLTRRGAAVLHAPALRIVPLADDSELLAATK
DLVDNPPDVVIATTAIGFRGWVEAADGWGIGDELLELLRGIELLARGPKVKGAIRAAGLT
EAWSPQSESMAEVLDRLLEEGVTGRRIALQLHGEPLPGFVESLRAAGAEIVGVPVYRWMP
PEDIAPLDRMLDATVGRGLDALTFTSAPAVASYLNRAETRGILPEVLDALGHDVLTACVG
PVTALPLQAKGIDTVQPERFRLGPLVQVLCAQLPARARALPVAGHRVEIRGHAVLVDGAL
RPVPPAGMALLHTLARRPGWVVSRADLLRALPGNGTDEHAVETAMARLRTALGAPRLIQT
VVKRGYRLALDPSADTKYDAVRPGG
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgcacgacgacgacgcacagcacgggcccctggcgggcttcacggtcggggtgaccgca
gcccgtcgcgccgaggagctcgggacgctcctcacgcgcaggggcgccgcggtcctgcac
gcgcccgcgctgcggatcgttccgctcgcggacgacagcgaactcctggccgcgaccaag
gatctcgtcgacaacccgccggacgtggtgatcgcgaccaccgccatcggtttcaggggc
tgggtggaggccgccgacggctggggcatcggtgacgagctcctcgaactgctgcgcggc
atagagctgctggcccgtggcccgaaggtcaagggcgccatccgggcggccgggctcacc
gaggcgtggtcgccgcagtcggagtcgatggcggaggtcctggaccggctgctggaggag
ggtgtgacgggccgccggatcgcactccagctgcacggcgaaccccttccgggcttcgtc
gagtcgctccgggcggcgggcgccgagatcgtcggcgtacccgtctaccggtggatgccc
ccggaggacatcgccccgctcgaccgcatgctcgacgccaccgtcggccgcggcctggac
gccctcaccttcaccagcgctcccgccgtcgcctcctacctgaaccgggcggagacccgc
ggcatccttcccgaggtgctggacgcactgggccacgacgtcctcacggcgtgcgtcgga
ccggtcaccgccctgcccctgcaggccaagggcatcgacaccgtgcagccggagcggttc
cggctcggacccctcgtccaggtgctctgcgcccagttgccggcccgggcccgcgcgctc
ccggtcgccggccaccgggtcgagatccgcggccacgccgtgctcgtcgacggggccctg
cgcccggtgcccccggccggcatggcgctgctgcacacgctcgcccgccggccgggctgg
gtggtctcccgcgccgacctgctgcgggccctgcccggcaacggaaccgacgagcacgcg
gtggagacggcgatggcccggctgcgcacggcactcggggccccgcggctgatccagacg
gtcgtcaagcggggctaccggctcgccctggacccctccgcggacaccaagtacgacgcg
gtccggcccggcggctag
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