Serratia fonticola GS2: AV650_03975
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Entry
AV650_03975 CDS
T04716
Symbol
metL
Name
(GenBank) bifunctional aspartokinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
sfg
Serratia fonticola GS2
Pathway
sfg00260
Glycine, serine and threonine metabolism
sfg00261
Monobactam biosynthesis
sfg00270
Cysteine and methionine metabolism
sfg00300
Lysine biosynthesis
sfg01100
Metabolic pathways
sfg01110
Biosynthesis of secondary metabolites
sfg01120
Microbial metabolism in diverse environments
sfg01230
Biosynthesis of amino acids
Module
sfg_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sfg_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sfg_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sfg00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AV650_03975 (metL)
00270 Cysteine and methionine metabolism
AV650_03975 (metL)
00300 Lysine biosynthesis
AV650_03975 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AV650_03975 (metL)
Enzymes [BR:
sfg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AV650_03975 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AV650_03975 (metL)
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Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
ALX92768
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Position
863777..866212
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AA seq
811 aa
AA seq
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MNAIAVAGPVSGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPGDMMVVSAAGSTTNQLIS
WLKLSQSDRLSAHQVQQTLRRYHSELIGGLLPAETAEPLIAEFIHDLERLAILLDGKVDD
AVYAEVVGHGEIWSARLMAAVLNKQDMQAAWLDARDFLRAERAAQPQVDEGRSYPLLQQL
LAQHPGKRLVVTGFISRNDSGETVLLGRNGSDYSATQVGALAGVERVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHTRTLQPVSGSDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDDVCLIELSVAPQHDFKLAQKELDLVLKRAQIKPLAVGVHPDRNL
IQLCYTSEVVGSVLRILQEAGLPGELQLREGLALVALVGAGVCKNPLHSHRFYQQLKDQP
VEFIWQAEDGISLVAVLRQGPTGLLIQGLHQTLFRAEKRIGLVLFGKGNIGSRWLELFAR
EQKNISARSGFEFSLAGVVDSRRSLLDYDGLDASRALAFFEDEAQELDEESLFLWMRAHP
FDDLVVLDVTASGELAEQYLDFASYGFHVISANKLAGASCSANYRQIRDAFAKTGRHWLY
NATVGAGLPVNHTVRDLRDSGDSILAISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGAEQGSIDQFFENGDALN
QQMLQRFEAANEMGLVLRHVARFDANGKARVGVEAVRPEHPLASLLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAQLL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgaatgcaattgcggtagcagggccggttagcgggcgtcaactgcacaaatttggcggc
agcagcctggcagatgtgaagtgttatctgcgggtggccgggatcatggccgaatacagc
cagccgggtgacatgatggtggtgtcggcggcggggagcaccaccaaccaactgatcagc
tggctgaagcttagccagagcgatcgcctttccgcgcatcaggtgcagcaaacgctgcgc
cgttatcacagtgagctgatcggcgggttgttgccggcggaaacggcggaaccgctgatt
gccgaatttatccacgatcttgagcgcctggcgatcctgttggacggcaaggttgatgat
gcggtgtatgccgaagtggtggggcacggtgagatctggtcagcacgcctgatggctgcg
gtgctgaacaagcaggacatgcaggcggcatggctggacgcgcgtgatttcctgcgtgcc
gaacgtgcggcacagccgcaggtcgacgaaggtcgttcctatccgttattgcagcaactg
ctggctcaacatcccggcaaacgtctggtagtaaccggctttatttcgcgtaatgacagc
ggtgaaaccgtgctgctggggcgcaacggcagtgactattccgccacgcaggttggcgcg
ttggccggagtggagcgagtcaccatctggagcgacgtggccggggtttacagcgccgat
ccgcgcaaagtgaaagatgcctgcctgctgccgctgttgcgtctggatgaggccagcgag
ctggcccgcctggcggctccggtgctacatacccgaaccctgcagccggtgtctggcagc
gatatcgatctgcaactgcgttgcagctatcagccggagcaggggtcgacccgtatcgag
cgcgtgctggcttccggcaccggtgccaaaattgtcaccagccacgatgatgtctgcctg
atcgaactcagcgttgcgccgcagcatgacttcaagctggcgcagaaagagttggatctg
gtgctcaagcgcgcgcagatcaaaccgttggccgtaggggttcatcctgaccgtaacctg
atccagctgtgctacacctctgaagtggtgggcagcgtgctgcgcattttgcaggaggct
gggctaccgggtgaactgcaactgcgtgaagggttggcgctggtagcgttggtgggcgcg
ggcgtgtgcaaaaatccgctgcatagccatcgtttctatcagcagttgaaggaccagccg
gtggagttcatctggcaggccgaggatggtatcagcctggtggccgtgctgcgtcaggga
ccgactggtctgctgatccagggcctgcaccaaacgctgttccgcgcggaaaagcgtatt
ggcctggtgctgtttggcaaaggcaatatcggttcgcgttggctggagctgtttgctcgt
gaacagaagaatatctctgcgcgcagcggctttgagtttagcctggcaggggtggtggat
agccgtcgcagcctgctcgattatgacggattggatgccagccgcgcgctggcgttcttt
gaagatgaagcgcaggaactggacgaagagtcgctgttcctgtggatgcgggcgcacccg
ttcgacgatctggtggtgctcgacgtcaccgccagtggggagttggcggagcaatatctg
gactttgccagctatggtttccatgtgatcagcgccaacaagctggcgggggcctcatgc
agcgccaattaccgccagatccgcgatgcgtttgccaaaacgggccgccactggctgtat
aacgccaccgtgggagccgggttaccggtgaaccataccgtgcgcgatctgcgcgacagc
ggggatagcatccttgcgatcagcggcatcttctccggcacgctttcctggctgtttctg
cagtttgacggcacggtgccgttcaccgatctggtggatcaggcctggcagcaggggctg
acggaaccggatccgcgtgttgacctgtcaggacaagacgtgatgcgtaagctggtgatc
ctggcgcgtgaagcgggttatgacattgaacctaaccaggtgcgtgtggagtcactggtg
cctgcaggtgcggagcaagggtccatcgaccagttcttcgagaacggcgacgcgctgaat
cagcaaatgctacagcgtttcgaagcggccaacgaaatgggcctggtgctgcgccacgtg
gcgcgtttcgatgctaatggcaaagcgcgcgttggcgttgaggccgtgcggccagaacac
ccgctggcttcgctgctgccctgtgacaacgtgtttgccatcgagagccgctggtaccgt
gacaacccgctggtgatccgtgggccaggggccggtcgcgacgtgacggctggagccatc
cagtccgaccttaaccgcttggcacaactgctttaa
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