Shigella flexneri 2457T (serotype 2a): S2477
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Entry
S2477 CDS
T00128
Symbol
menD
Name
(GenBank) 2-oxoglutarate decarboxylase; SHCHC synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
sfx
Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00130
Ubiquinone and other terpenoid-quinone biosynthesis
sfx01100
Metabolic pathways
sfx01110
Biosynthesis of secondary metabolites
sfx01240
Biosynthesis of cofactors
Module
sfx_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
sfx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
S2477 (menD)
Enzymes [BR:
sfx01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
S2477 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AAP17676
UniProt:
Q821B0
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Position
complement(2369776..2371446)
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AA seq
556 aa
AA seq
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MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGH
LALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAI
RQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDD
TGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQAS
CEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAV
IARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDG
LLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PQSERERFYLMPQNVHFEHAAAMFELKYHHPQNWQELETAFADAWRTPTTTVIEMVVNDT
DGAQTLQQLLAQVSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtaagcgcatttaaccgacgctgggcggcggtcattctggaagcattaacgcgt
cacggcgtcagacacatctgtatcgccccaggctcgcgttctacaccgttaacgttagcg
gcggcggagaattccgcattcattcaccacacccatttcgatgagcgtgggttggggcat
ctggcgctggggctggcgaaagtcagcaagcagccggtggcggtgattgtgacctccggc
acggcggtggcaaatctctatccggcactgattgaagccgggttaaccggagaaaaactg
attctcttaaccgccgatcgcccgccggagctaattgactgcggcgcgaatcaggcaatt
cgccagccgggaatgttcgcctctcaccccacgcacagtatttcattgccgcgcccgacc
caggatatccccgcacgttggctggtttctaccatcgaccacgctctcggtacgcttcat
gcggggggagtccatatcaactgcccgtttgctgaaccgctgtatggcgaaatggacgat
accgggcttagctggcaacagcgtctgggtgactggtggcaggacgacaaaccgtggctg
cgtgaagcgcctcgtctggaaagtgaaaaacagcgcgactggttcttctggcgacaaaag
cgcggcgtggtggttgccgggcgcatgagtgcggaagagggcaaaaaagttgccctgtgg
gcgcaaactcttggctggccgctgattggcgatgtgctgtcacaaaccgggcagccgctg
ccgtgtgccgatctttggttaggcaatgccaaagcgaccagcgagctgcagcaggcgcaa
attgtggtgcaactgggaagtagcctgacggggaaacggctcctgcaatggcaggcaagc
tgtgaaccagaagagtactggattgttgatgacattgaagggcgacttgatccggcacac
catcgcggacgtcgcttaattgccaatattgccgactggctggagctgcatccggcagaa
aaacgccagccctggtgcgttgaaatcccgcgcctggcggaacaggcaatgcaggcggtt
attgcccgccgtgatgcgtttggcgaagcgcaactggcgcatcgcatcagcgactatctg
cctgaacaggggcaattgtttgttggtaacagcctggtggtacgtctgattgatgcgctt
tcgcaacttccggcaggttacccggtgtacagcaaccgaggggccagcggtatcgacgga
ctgctttcgaccgccgcaggcgttcagcgggcaagcggcaaaccgacgctggcgattgtg
ggcgatctctccgcgctttacgatctcaacgcgctggcgttattgcgtcaggtttctgcg
ccgctggtattaattgtggtgaacaacaacggcgggcaaattttctcgctgttgccaacg
ccgcaaagcgagcgtgagcgtttctatctgatgccgcaaaacgtccattttgagcacgcc
gccgcgatgttcgagctgaaatatcatcatccgcaaaactggcaggaacttgaaacggca
tttgccgacgcctggcgcacgccaaccaccacggtgattgaaatggtggttaacgacacc
gatggtgcgcaaacgctccagcaacttctggcgcaggtaagccatttatga
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