Streptomyces griseochromogenes: AVL59_07110
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Entry
AVL59_07110 CDS
T04729
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgs
Streptomyces griseochromogenes
Pathway
sgs00020
Citrate cycle (TCA cycle)
sgs00630
Glyoxylate and dicarboxylate metabolism
sgs00785
Lipoic acid metabolism
sgs01100
Metabolic pathways
sgs01110
Biosynthesis of secondary metabolites
sgs01120
Microbial metabolism in diverse environments
sgs01200
Carbon metabolism
sgs01210
2-Oxocarboxylic acid metabolism
Module
sgs_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgs_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AVL59_07110 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AVL59_07110 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AVL59_07110 (kgd)
Enzymes [BR:
sgs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AVL59_07110 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AVL59_07110 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AVL59_07110 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AVL59_07110 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ANP49396
UniProt:
A0A1B1AS63
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All DBs
Position
complement(1509852..1513658)
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AA seq
1268 aa
AA seq
DB search
MSPQSPSNSSISTDDQAGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPG
APAAAAGAAETATTAPQAQPAAPAAPAPAAPAPAPAAPKPAAAAPAPAPAKAPAPAPAKP
ATPAQAPAQPKAKAAPAAPAAAAAPEGPELITLRGPAAAVAKNMNASLELPTATSVRAVP
VKLLFDNRIVINNHLKRARGGKISFTHLIGFAMVQAIKAMPSMNWSFGEKDGKPTLVKPA
HVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARDGKLTMDDFTGVT
VSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTY
DHRVIQGAASGEFLRQVSNLLLGENGFYDDIFKALRIPYEPVRWLKDIDASHDDDVTKAA
RVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSLMK
LRDILGVLRDSYCRTIGIEFMHIQDPKQRKWIQDRVERPHTKPEREEQLRILRRLNAAEA
FETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVG
KSYAQIFREFEGNLDPKSMHGSGDVKYHLGAQGTFTGLDGEQITVSLAANPSHLETVDPV
IEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVI
NNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVV
IDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDY
QGQLEKVFTEVREATSQPTAADVQAPQDGFPVAVPTAISSEVVKRIAESQVNIPDQFTVH
PRLLPQLQRRTTMVEDGTIDWGMGETLAVGSLLLEGTPVRLSGQDSQRGTFGQRHAVLID
RETGEEFTPLMYLAEEQARYNVYNSLLSEYAVMGFEYGYSLARPDALVMWEAQFGDFVNG
AQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDHSSARVERFLQLCAQNNMTVAMPT
LPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTSGEFRPVIGDASITDAA
AVKKVVFCAGKVYYDLEAERQKRGATDTAIIRLERLYPLPGAEIQAEVNKYPNAEKYLWV
QEEPANQGAWPFIALNLIDHLDLAVGPDVPHGERLRRISRPHGSSPAVGSAKRHQAEQEQ
LVREVFEA
NT seq
3807 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgatgaccaagccgggaagaac
cccgctgctgcgttcggtcccaacgagtggctcgtcgacgagatctatcagcagtacctc
caggacccgaattcggtagaccgtgcctggtgggacttcttcgccgattacaagccgggt
gcgccggctgcggccgcgggggccgcagagaccgccaccacggctccgcaggcccagccc
gcggctccggcggccccggcaccggcggccccggcaccggctcccgcggctccgaagccc
gcggcggccgctccggccccggcgcccgcgaaggctcccgctcccgccccggccaagccg
gcgacgcccgcacaggcgcccgctcagccgaaggcgaaggccgcgcccgccgcacccgcc
gccgcggcggccccggagggccccgagctgatcacgctgcgcggcccggccgccgcggtc
gcgaagaacatgaacgcctccctggagctgccgacggccacctcggtccgcgcggtcccg
gtgaagctgctgttcgacaaccggatcgtcatcaacaaccacctgaagcgcgcccggggc
gggaagatctccttcacgcacctgatcggcttcgcgatggtgcaggccatcaaggccatg
ccgtcgatgaactggtcgttcggcgagaaggacggcaagccgaccctcgtcaagccggcg
cacgtcaacctcggcctggccatcgacctggtcaagccgaacggtgaccgccagctcgtc
gtggccgccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgag
gacatcgtccgccgcgcccgcgacggcaagctgacgatggacgacttcaccggtgtcacg
gtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcggctgatgccc
ggccagtccgtgatcatgggcgtcggctccatggactacccggcggagttccagggcacc
agccaggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctac
gaccaccgggtgatccagggcgccgcctccggcgagttcctgcgccaggtctcgaacctg
ctgctgggcgagaacggcttctacgacgacatcttcaaggcgctgcgcatcccctacgag
ccggtccgctggctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcc
cgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgac
ccgctggagtaccgccagcgcaagcaccccgacctggacatcaccgagcacggcctcacc
ctgtgggacctggagcgcgagttcgccgtcggcggcttctccggcaagtccctgatgaag
ctgcgcgacatcctcggtgtcctgcgcgactcgtactgccgcaccatcggcatcgagttc
atgcacatccaggaccccaagcagcgcaagtggatccaggaccgcgtcgagcgcccgcac
accaagccggagcgcgaggagcagctgcgcatcctgcgccggctgaacgccgccgaggcc
ttcgaaaccttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggc
gaatccgtcatcccgctgcttgacgcggtcatcgacagcgccgccgagtcgcgcctggac
gaggtcgtcatcggcatggcccaccgcggccgtctgaacgtcctcgccaacatcgtcggc
aagtcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcac
ggctccggcgacgtgaagtaccacctgggcgcccagggcaccttcaccggcctggacggc
gagcagatcacggtctcgctggccgccaacccgtcccacctggagacggtcgacccggtc
atcgagggcatcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcacc
gtcctgccggtcgcgctgcacggcgacgcggccttcgcgggccagggcgtggtggccgag
accctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatcgtcatc
aacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctccatgtacgcgacg
gacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggcc
gtggtccgcgtcgcgcggctcgccttcgagttccgccaggcgttcaacaaggacgtggtg
atcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacc
cagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgag
tccctgatcggtcgcggcgacatcaccctggaagaggccgagcaggcgctgcaggactac
cagggccagctggagaaggtcttcaccgaggtccgcgaggccacgtcccagccgaccgcc
gcagacgtccaggcgccgcaggacggcttcccggtcgcggtcccgaccgcgatctcctcg
gaggtcgtcaagcgcatcgccgagtcccaggtcaacatccccgaccagttcaccgtccac
ccgcgtctgctgccgcagctgcagcgccggacgacgatggtcgaggacggcacgatcgac
tggggcatgggcgagaccctggccgtcggctccctgctgctggagggcaccccggtccgc
ctgtccggccaggactcccagcgcggcaccttcggccagcgccacgcggtcctcatcgac
cgcgagacgggcgaggagttcacgccgctgatgtacctcgccgaggagcaggcgcggtac
aacgtctacaactccctcctgtccgagtacgcggtcatgggcttcgagtacggctactcg
ctggcccgtcccgacgcgctcgtgatgtgggaggcgcagttcggcgacttcgtcaacggt
gcgcagacggtggtcgacgagtacatctcggcggcggagcagaagtggggccagacgtcc
ggcgtcaccctcctcctcccgcacggctacgagggccagggcccggaccactcctcggcc
cgtgtcgagcgcttcctgcagctctgcgcgcagaacaacatgacggtcgcgatgcccacg
ctcccgtcgaactacttccacctcctgcgctggcaggtgcacaacccgcaccacaagccg
ctgatcgtcttcaccccgaagtcgatgctgcgtctgaaggcggcggcctcgaaggcggag
gagttcacgagcggcgagttccgcccggtcatcggcgacgcgtcgatcaccgacgcggcg
gccgtgaagaaggtcgtcttctgcgcgggcaaggtctactacgacctggaggccgagcgt
cagaagcgcggcgccacggacacggcgatcatccgcctcgagcgtctgtacccgctgccg
ggtgcggagatccaggcggaggtcaacaagtacccgaacgccgagaagtacctgtgggtc
caggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgaccac
ctggacctggcggtcggcccggacgtcccgcacggcgagcgtctgcggcgcatctcgcgt
ccgcacggttcgtccccggccgtgggctccgccaagcgccaccaggccgagcaggagcag
ctggtgcgtgaggtgttcgaggcgtaa
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