Sarcophilus harrisii (Tasmanian devil): 100913437
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Entry
100913437 CDS
T02286
Gene name
NOS3
Definition
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00220
Arginine biosynthesis
shr00330
Arginine and proline metabolism
shr01100
Metabolic pathways
shr04020
Calcium signaling pathway
shr04022
cGMP-PKG signaling pathway
shr04066
HIF-1 signaling pathway
shr04071
Sphingolipid signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04370
VEGF signaling pathway
shr04371
Apelin signaling pathway
shr04611
Platelet activation
shr04915
Estrogen signaling pathway
shr04921
Oxytocin signaling pathway
shr04926
Relaxin signaling pathway
shr04931
Insulin resistance
shr04933
AGE-RAGE signaling pathway in diabetic complications
shr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100913437 (NOS3)
00330 Arginine and proline metabolism
100913437 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100913437 (NOS3)
04371 Apelin signaling pathway
100913437 (NOS3)
04066 HIF-1 signaling pathway
100913437 (NOS3)
04020 Calcium signaling pathway
100913437 (NOS3)
04071 Sphingolipid signaling pathway
100913437 (NOS3)
04022 cGMP-PKG signaling pathway
100913437 (NOS3)
04151 PI3K-Akt signaling pathway
100913437 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100913437 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100913437 (NOS3)
04921 Oxytocin signaling pathway
100913437 (NOS3)
04926 Relaxin signaling pathway
100913437 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100913437 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100913437 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100913437 (NOS3)
Enzymes [BR:
shr01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100913437 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100913437
NCBI-ProteinID:
XP_031795271
Ensembl:
ENSSHAG00000009161
LinkDB
All DBs
Position
5
AA seq
1193 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCSKQSGSPGPENGGPAVADVSPPVARPPEGPKFSR
IKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPKQLQSRPTEGPPSPGQLLIQARDF
INQYYSSIKRSGSPAHGQRLREVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQW
GKLQVFDARDCSSAQEMFTYICNHIKYATNKGNLRSAITVFPQRSQGKGDFRIWNSQLIR
YAGYRQQDGSVLGDPANVEITELCIQHGWTPKNGRFDVLPLLLQASDEPPELFPLPPELV
LEVPLQHPTLEWFESLGLRWYALPAVSNMLLEIGGLEFPAVPFSGWYMSSEIGMRNLCDP
HRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAATASFMKH
LENEQRARGGCPADWVWIVPPISGSLTPVFHQEMVNYFLSPAFHYQPDPWKGTATKGTGI
TRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRV
LCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGERFAAALMEMSGPYNSSPRPEQHKSYK
IRFNSVSCSDTLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTR
LEELGGERLLQLGQGDELCGQEEAFQGWAQAAFQASCETFCVGDDAKAAARDIFSPKRSW
KRQRYRLSAQPEGLQLLPGLIHVHRRKMFPATVLSVENLQSSKSTRATILVRLATGGQEG
LQYQPGDHIGICPPNRPGLVEALLSRVEDPPLPSEPIAVEQLEKGSPGSPPPGWVRDPRL
PSCTLQQALTFFLDITSPPGPQLLRLLSTLAEEPSEQQELEALSKDARRYEEWKWFRCPT
LLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAYRTQDGLGP
LHYGVCSSWLSQLKAGDVVPCFIRGAPSFRLPSDPSVPCILVGPGTGIAPFRGFWQERLH
DLEHKGLRPAPMTLVFGCRCSQLDHLYREEVHEAQRRGVFGRVLTAFSREPDSPKTYVQD
VLRAELAPEVHRVLCLEGGHMFVCGDVTMATSVLQTVQRILATEGGMELSEAGDVIGVLR
DQQRYHEDIFGLTLRTQEVTNRIRTQSFSLQERQARSAVPWALADPTPETPES
NT seq
3582 nt
NT seq
+upstream
nt +downstream
nt
atgggcaatttgaagagtgtgggtcaggagcccggaccaccctgcggactggggctggga
ctggggctgggactatgcagcaaacagagtgggagcccaggacctgagaatgggggtcca
gccgtggcggacgtcagccccccagtagcccggccaccggaggggcccaaattctccaga
ataaagaactgggaagtaggaagtatcacctacgacactctgagtgcccaagcccagcag
gatgggccctgtaccccaaggcgttgcctgggctcccttgtgtttccaaagcaactgcaa
agccgccccacggaggggcccccgtcccccggccagctactcatccaggcccgagatttc
attaaccaatactacagctctatcaagaggagcggctccccagcccatggacaacggctt
cgggaagtggaagctgaagtggcggccacaggcacctaccagctccgggagagtgagctt
gtatttggggctaagcaggcctggagaaatgcccctcggtgtgtgggcaggatacagtgg
ggaaagctgcaggtgtttgatgcccgagattgcagctctgctcaggagatgttcacctat
atctgcaatcacatcaaatatgctaccaacaaaggcaaccttcgctcagccatcacagtg
ttcccacagcgctcccaaggcaagggggacttccgtatctggaacagccagctgatccga
tacgcgggctaccggcagcaagatggctctgtcttgggggaccctgccaacgtggagatc
actgagctctgcatccagcatggctggacccccaagaacgggcgctttgatgtgctgccg
ctgctgctccaggcctctgatgagccgcctgaactcttccctctgcctcctgaacttgtg
ctcgaggtgccgttgcaacatcccacgctggagtggtttgagtccttgggccttcgctgg
tacgccctcccggctgtgtccaacatgctgctggagatcggggggctggagttccccgca
gtgcccttcagcggctggtacatgagcagtgagattgggatgcgcaacctgtgtgacccc
caccgctacaacatcctagaggacgtggccgtctgcatggacctggacacaaggacaacc
tcatctctgtggaaggacaaggcagcagtggagatcaacctggccgtgctgcacagctac
caactggccaaagtgaccatcgtggatcaccacgcggccacggcctccttcatgaagcac
ctggagaacgagcagcgggcgcggggcggctgccctgcagactgggtctggattgtccca
ccaatctccggcagcctcacccccgtctttcaccaggaaatggtcaactacttcctgtcg
cctgcgttccactaccagcctgatccatggaaggggacagcaacaaaaggaactggaatc
acccggaaaaaaacatttaaggaagtggccaacgcagtgaagatctcggcttccctgatg
ggcacagtgatggccaagcgggtgaaggcgacgattctgtacggctcagaaactggccgt
gcccaaagctacgctcagcagctggggaggctgttccggaaggccttcgatccccgggtc
ctctgcatggatgagtatgacgtagtgtccctggagcatgagaccctggtcctggtggta
actagcacattcgggaatggagaccctccagaaaatggagagagatttgcagccgccctg
atggaaatgtctggcccctacaacagctctcccagaccagagcagcacaaaagctacaag
attcgcttcaacagcgtctcctgctcagacacgctggtgtcctcgtggcggcggaagagg
aaggaatccagtaacaccgacagtgcgggagccttagggaccctgaggttctgtgtgttt
gggctcggctcccgtgcctacccccacttctgtgcttttgcccgggctgtggatacccgt
ctggaagagctggggggagagaggctactgcagctgggccagggggacgagttatgtggc
caggaagaggctttccagggctgggcccaagctgcattccaggcctcctgtgagaccttc
tgtgtgggggacgatgccaaagctgctgcccgggacatattcagccccaagagaagttgg
aaacgccaaagataccgcctgagtgcccagccagaggggctccagctgctgccgggcctg
atacatgtacacaggaggaagatgttcccagccaccgtcctctcggtggaaaacctacag
agcagcaagtcaactcgggccacaatcctggttcgtctggccacaggggggcaggagggc
ctgcagtatcagcctggcgaccacattgggatctgcccccccaaccggcctggcctggtg
gaggccctgttgagccgagtagaggatccacccctgcccagtgagcctattgctgtggag
cagctggagaaggggagcccaggcagcccacccccaggctgggtccgggacccccggctg
ccctcatgcacattacagcaggccctcacctttttcctggacatcacctcccccccgggg
cctcagctccttcgcctgctcagcaccctggcagaggagcccagcgagcagcaagagctg
gaggctctcagcaaggatgctcggcgctatgaggaatggaaatggttccgctgccccacg
cttctggaggtgctggagcagttcccgtcggtggccctgccagcgcctctgctcctcacc
cagctgcctctgctccagccacggtactactcagtcagctctgcccccagtgcccacccc
ggggagatccacctcacagtggctgtgctggcctacaggacccaggatgggctcggcccc
ctgcactatggggtctgctcctcgtggttaagtcagctcaaggctggagacgtagttccc
tgcttcatcaggggagctccatccttccggctgccgtccgaccccagcgtgccctgcatc
ctggtggggccgggcacgggcatcgcccccttccgcgggttttggcaggagcggctacac
gacctggagcacaaaggactgcgtcccgcccccatgaccctggtcttcgggtgccgctgc
tcccagctggaccacctgtaccgagaggaggtgcacgaggcgcagcgtcgaggggtcttc
ggccgcgtgctcacagccttttccagggagcccgacagccccaagacctacgtgcaggac
gtcctgcgggcagagctggcccccgaggtgcaccgcgtgctgtgcctcgagggcggccac
atgttcgtctgcggcgacgtcactatggcgaccagcgtgctgcagacggtgcagcggatc
ctggccacggagggcgggatggagttgagcgaggccggagacgtcatcggggtgctgcgg
gaccagcagcgctaccacgaggacatcttcgggctgacgctgcgcacgcaggaggtgacg
aaccgcattcgcacgcagagcttctccctgcaggagcggcaggcgcggagcgccgtgccc
tgggctctggccgatcccaccccggagaccccggagtcctga
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integrated database retrieval system
