Sarcophilus harrisii (Tasmanian devil): 100914727
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Entry
100914727 CDS
T02286
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr01522
Endocrine resistance
shr01524
Platinum drug resistance
shr04010
MAPK signaling pathway
shr04012
ErbB signaling pathway
shr04020
Calcium signaling pathway
shr04066
HIF-1 signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04510
Focal adhesion
shr04520
Adherens junction
shr04530
Tight junction
shr05200
Pathways in cancer
shr05205
Proteoglycans in cancer
shr05206
MicroRNAs in cancer
shr05212
Pancreatic cancer
shr05213
Endometrial cancer
shr05215
Prostate cancer
shr05219
Bladder cancer
shr05223
Non-small cell lung cancer
shr05224
Breast cancer
shr05226
Gastric cancer
shr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100914727 (ERBB2)
04012 ErbB signaling pathway
100914727 (ERBB2)
04066 HIF-1 signaling pathway
100914727 (ERBB2)
04020 Calcium signaling pathway
100914727 (ERBB2)
04151 PI3K-Akt signaling pathway
100914727 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100914727 (ERBB2)
04520 Adherens junction
100914727 (ERBB2)
04530 Tight junction
100914727 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100914727 (ERBB2)
05206 MicroRNAs in cancer
100914727 (ERBB2)
05205 Proteoglycans in cancer
100914727 (ERBB2)
05230 Central carbon metabolism in cancer
100914727 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100914727 (ERBB2)
05226 Gastric cancer
100914727 (ERBB2)
05219 Bladder cancer
100914727 (ERBB2)
05215 Prostate cancer
100914727 (ERBB2)
05213 Endometrial cancer
100914727 (ERBB2)
05224 Breast cancer
100914727 (ERBB2)
05223 Non-small cell lung cancer
100914727 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100914727 (ERBB2)
01524 Platinum drug resistance
100914727 (ERBB2)
01522 Endocrine resistance
100914727 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100914727 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
shr04147
]
100914727 (ERBB2)
04090 CD molecules [BR:
shr04090
]
100914727 (ERBB2)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100914727 (ERBB2)
Protein kinases [BR:
shr01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100914727 (ERBB2)
Exosome [BR:
shr04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100914727 (ERBB2)
CD molecules [BR:
shr04090
]
Proteins
100914727 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
PTP_tm
Motif
Other DBs
NCBI-GeneID:
100914727
NCBI-ProteinID:
XP_012403823
Ensembl:
ENSSHAG00000015078
UniProt:
G3WQQ2
LinkDB
All DBs
Position
4
AA seq
1255 aa
AA seq
DB search
MDLPGCCCWGLLLVLLPPAVWGTQVCTGTDMKLQYPASIENHLDTLSHLYQGCQVVQGNL
ELTYLPADANLSFLQDIQEVQGYVLIAHSLVRSFPLQRLRIIRGTQLFEDKYALVVLDNG
IPLGTAPPTAEGPPGLRELQLRSLTEILKGGVLIQKNPQLCHQDTVLWADIFHKNNRLGT
TSIDTNHSRTCNPCSSSCKSGQCWGEGHDNCQNLTRTICASGCARCKGPLPTDCCHEQCA
AGCTGPKHSDCLACLHFNHSGICEQHCPPLVIYNSDTFESMPNPDGRYTFGSSCVKSCPY
NYLATDVGSTSCTLVCPLHSQEVTAEDGTHRCEKCSKACPKVCYGLGMGHLRSVRAVNST
NIQDFAGCKKIFGSLAFFPETFSGDLATNTSPLMPEDLKVFENLEEITGYLYISAWPDSL
PDLSIFQNLRVIRGRVLHNGVYSLTLEHLGIGWLGLRSLRELGSGLALIHHNAHLCFVHT
VPWNQLFRNPRQALLYSANRPAQECESKGLTCYSLCAQGHCWGPGPTQCLNCSQFLRGQE
CVEECRVLQGYPREYVKERRCFPCHEECQPQNGTETCFGSEADKCVACVHFKDPPSCVAR
CPSGVKPDLSFIPIWKYPDDEGICQTCPTNCTHSCTVLDEKGCPAEQKPSPVTSIIAGVV
GVLLALIIGLIIGILIKRRKQKERKHTMRRLLQETELVEPLTPSGALPNQAQMRILKETE
LRKVKVLGSGAFGTVYKGIWIPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGS
PYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLCSQDLLNWCVQIAKGMNYLEEV
RLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILCRRF
THQSDVWSYGVTVWELMTFGAKPYEGIPAREIPDLLEKGDRLPQPPVCTIDVYMIMVKCW
MIDSECRPRFRELVTEFSRMARDPQRFVVIQNEDSGPASPLDSTFYRSLLEEDDMSDLVD
AEEYLVPQQGFFCPDPPLAPGPGGTAHRRHRSSSTRSGGELPGGLEGAEEDPPQSSAEPW
EATGSDVFDGDPGGSPKGLKGLPPRDLSPLQRYSEDPTGPLTPEMDGYIVPPVCGPLPEY
VNQPEVHLPPSSPREGTLTPPHPSNSTLERPKLPPPGKNGVVKDTFTFGAAVENPEYLAP
HGGGPLHLPPTFSSPAFDNLYYWDQDPPDRGAAPNGFAGTPTAENPEYLGLDMPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggacctgcccggctgctgctgttgggggctccttctggtcctcctgcccccagcagtc
tggggaacccaagtgtgcacaggcacagacatgaagctgcagtatcctgccagtatcgag
aatcaccttgacacactgagccacctgtaccaaggatgccaggttgtacagggcaatctg
gagctcacttacctgcctgctgatgccaacctctccttcctccaggacatccaggaagtg
cagggatatgtgctgattgctcacagcctggtgaggagtttcccactgcagaggctaaga
atcattcgaggaacgcagctctttgaagacaaatatgccctagtcgttctggacaacggg
attccccttgggaccgctcctcctacagcggaggggccccctggccttcgggaactgcaa
cttcgaagcctcacagagattctgaaaggcggggttctgatccagaagaatcctcagcta
tgtcaccaagacacagtgttgtgggctgacatcttccataagaacaaccgcttgggtacc
acctccatcgacacaaaccacagccgaacttgcaacccttgctcttcatcatgtaaatcc
ggacagtgttggggagaaggacacgacaactgtcagaacttgacccgcacaatttgtgcc
agtggctgtgctcgctgcaaggggcccctccccacagactgctgccacgagcagtgtgct
gctggctgcactggccccaagcattctgactgcctggcctgcctccacttcaaccacagt
ggcatctgtgagcagcactgcccaccgctggtgatctacaattcagacacctttgagtca
atgcctaatcctgatgggcgctacacctttgggtccagttgtgtgaaatcatgtccctat
aattacctagccacagatgtgggctctacatcctgtaccctcgtgtgtcccctacacagt
caagaggtgaccgctgaggacggaacccatcggtgtgagaagtgcagcaaagcctgcccc
aaagtgtgttatgggctgggcatgggccacttgagatcagtgagagcggtcaacagcact
aatatccaggattttgcgggctgcaagaagatctttggaagtctggccttcttccccgag
accttctctggggacttggctaccaatacttctccattaatgcccgaagacctcaaggtc
tttgagaacctggaggagattacaggctatctgtacatctcggcctggcccgacagcctc
cctgatctcagcatctttcagaacctcagggtgatcaggggaagggtgttgcacaatggt
gtctactccctgacgctggagcatctgggtattggctggctggggctgcggtcactgaga
gagctgggcagtgggctggcactcatccatcacaatgcccacctatgctttgtccacacg
gtaccttggaaccaactcttccgcaacccccgccaggccctgctctacagcgccaaccga
cctgcccaggagtgtgaaagcaaggggctcacgtgctactccctgtgtgcccaggggcac
tgctggggccctgggcctacccagtgtctcaactgcagccagtttctccgagggcaggag
tgtgtggaggagtgccgggtcctgcaggggtacccccgggagtatgtaaaggagagacgc
tgtttcccgtgccatgaggagtgccagccccagaatggcacagaaacctgctttggatcg
gaggctgacaaatgtgtagcctgtgtccacttcaaggaccccccttcctgcgtggcccga
tgccccagtggggtgaagcccgacctctccttcatacccatctggaagtatccagatgat
gagggcatttgccagacctgccccaccaactgtacccactcctgtactgtattggatgaa
aaaggctgtcctgctgagcagaaacccagccccgtgacctccatcattgctggggtggtt
ggggtgcttctagccctcatcataggcctgatcattggcatcttgattaagcgtcggaaa
cagaaggaacggaagcacaccatgaggaggctgcttcaggagacagagctggtggagccc
ttgacgcccagcggagcgctgcccaaccaagcgcagatgcgaatcctaaaagagacagag
ctgaggaaagtgaaggttcttggctctggggccttcggcacagtctacaagggtatttgg
atccctgatggtgaaagtgtgaaaatccccgtggctatcaaggtgttgagggaaaacaca
tcccccaaagccaacaaggagatcttggatgaagcatacgtgatggcaggggtcggctcg
ccgtatgtgtctcgccttctgggcatctgcctgacatccacagtgcagctagtgacccag
ctgatgccctatggctgcctcctggaccacgttcgggaaaatcgagggcggctctgctcc
caggacctcctcaactggtgtgtgcagattgccaaggggatgaactacctggaggaggtt
cggctagtgcacagagacctggctgccagaaatgtgctggtcaagagtcccaaccacgtc
aagatcacagacttcggactggccaggctcttggacatcgatgagacagagtaccacgca
gatgggggcaaggtccccatcaagtggatggccctggagtccattctctgccggagattc
acccatcagagcgatgtgtggagctacggggtgacagtgtgggaactgatgacctttggg
gccaaaccatatgaggggattccagctcgagagattccggacctgctggagaagggggac
cggctgcctcagccccctgtctgcaccatcgatgtctacatgatcatggttaaatgttgg
atgattgactctgagtgtcggcctcggttccgggaactggttactgaattttcacgaatg
gcccgagaccctcagcgctttgtggtcattcagaatgaggattctggcccagccagcccc
ctggacagcactttctaccgctcactgttggaggaagacgacatgagtgacttagtggat
gcagaagaatacctggtgccccagcaaggcttcttctgccctgaccctcccttggctcca
gggcctggaggcactgcccatcgaaggcacagaagttcttctacgaggagtggtggggag
cttccaggaggactggaaggtgctgaagaggaccctccacaatcttcagcagaaccttgg
gaagcaactggttctgatgtgtttgatggggaccctggagggagccctaagggactaaag
ggactcccccctagagacctcagccccctgcagcgctacagtgaggatccgacaggacca
ctgacccctgagatggatggctatattgtcccacccgtctgtggccccctgcctgaatac
gtgaaccagccagaggtgcacctaccaccctcttctccccgggaggggaccctgactccc
cctcacccatccaactccaccttggaacgtcccaagttgcctcctccagggaagaatgga
gtggtcaaagacacatttacctttggcgcagctgtggagaaccccgagtacttggccccc
catggtgggggtccccttcatcttcctccaactttctccagcccagcctttgacaacctc
tactactgggaccaggatccccctgatcgaggagctgcccctaatggctttgcagggacc
cccacagccgagaaccctgagtacttgggtttggatatgcctgtgtga
DBGET
integrated database retrieval system
