Sarcophilus harrisii (Tasmanian devil): 100917007
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Entry
100917007 CDS
T02286
Gene name
MET
Definition
(RefSeq) hepatocyte growth factor receptor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr04010
MAPK signaling pathway
shr04014
Ras signaling pathway
shr04015
Rap1 signaling pathway
shr04020
Calcium signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04360
Axon guidance
shr04510
Focal adhesion
shr04520
Adherens junction
shr05100
Bacterial invasion of epithelial cells
shr05144
Malaria
shr05200
Pathways in cancer
shr05202
Transcriptional misregulation in cancer
shr05205
Proteoglycans in cancer
shr05206
MicroRNAs in cancer
shr05211
Renal cell carcinoma
shr05218
Melanoma
shr05223
Non-small cell lung cancer
shr05225
Hepatocellular carcinoma
shr05226
Gastric cancer
shr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100917007 (MET)
04014 Ras signaling pathway
100917007 (MET)
04015 Rap1 signaling pathway
100917007 (MET)
04020 Calcium signaling pathway
100917007 (MET)
04151 PI3K-Akt signaling pathway
100917007 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100917007 (MET)
04520 Adherens junction
100917007 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
100917007 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100917007 (MET)
05202 Transcriptional misregulation in cancer
100917007 (MET)
05206 MicroRNAs in cancer
100917007 (MET)
05205 Proteoglycans in cancer
100917007 (MET)
05230 Central carbon metabolism in cancer
100917007 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100917007 (MET)
05226 Gastric cancer
100917007 (MET)
05218 Melanoma
100917007 (MET)
05211 Renal cell carcinoma
100917007 (MET)
05223 Non-small cell lung cancer
100917007 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100917007 (MET)
09174 Infectious disease: parasitic
05144 Malaria
100917007 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100917007 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100917007 (MET)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100917007 (MET)
Protein kinases [BR:
shr01001
]
Receptor tyrosine kinases (RTK)
MET family
100917007 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Sema
Pkinase
TIG
PSI
Pkinase_fungal
Kinase-like
LapA_dom
Motif
Other DBs
NCBI-GeneID:
100917007
NCBI-ProteinID:
XP_003771590
Ensembl:
ENSSHAG00000015881
UniProt:
G3WTF3
LinkDB
All DBs
Position
5
AA seq
1379 aa
AA seq
DB search
MKPPAVLVPGITMLLLALVPNCKAECKEALVKSEMDVNRKYPLPNFIAETPIQNIVFHNH
HIFLGAINKIYVLNEDLHNVSEYKTGPVLEHPDCSPCQDCSHKANLSGSVWKDNVNKALL
IDTYYDDQLISCGSVNRGTCQRHVFQPNNAADIQSQVYCIYSPQMDEESLQCPDCVVSTL
GTKVLLTEKDRFINFFVGNTINSSYADHSSHSISVRRLKETQDGFKFLTDQSYIDVLPEF
QDSYPIKYIHAFESSDFIYFLTVQRETLESQTFHTRIIRFCSIDSGLHSYMEMPLECILT
EKRRKRSPREEVFNVLQAAYVSKPGAHLARQIGVGPNDDIIFGVFAQSKPDSSEPIKRSA
VCAFPIKFVNDFFNRIVNKNNVRCLQHFYGNNHKHCFNRTFLRNSSGCEARDDEYRTEFT
TGLQRIDLFTGQFKQVLLTSISTFIKEDLTIANLGTSDGRFMQVVVSRGQSTPHVNFQLD
SHPVSPEVIVEHPLNADGFTLVITGKKITKIPLNGLGCDHFKSCSQCLSAPPFVQCTWCH
NQCVKSKECVTELGNQDICLPTIYEILPTSAPLEGGTTLTVCGWDFGLRKNNKFDFRKTK
VFIGNESCILNTSESTTNKLKCTVGPAVNLHFNVSIIISNGRETTKFNSFSYVDPVITNI
SPSYGPKAGGTVLTLIGKYLNSGNSRRISIGGKPCILKSVSHSLLECYTPAQTIPSEYPI
KMKIDLANREAYSFTYKEDPIVHKIHPTKSFLSGGSTITGFGKNLNSASVPKMVINVPEV
GRNFTVACKHRSNSEIICCSTPSLQQLNLQPPLETKALFIFDGIHSTYFDLIYVHNPVFK
PFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIRLNSETVLCTVPSDLLK
LNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVLISLLLLFLLGLFLWLKKRKQIK
DLGSDLVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPHSSQNGSCR
QAHYPLTDLSPILTSADSDISSPLLQNHVHIDISALNPDLVQAVQHVVIGPNSLIVHFNE
IIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVH
RDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTT
KSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP
KAEMRPSFSELVSKISVIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSQDNVDREVDT
NT seq
4140 nt
NT seq
+upstream
nt +downstream
nt
atgaagccccctgctgtgcttgtacctgggattacaatgttactgcttgccttggtgccg
aattgcaaagcagagtgtaaggaagccctagtcaagtctgaaatggatgttaataggaag
tatccacttcccaacttcattgcagaaaccccgatccaaaacatcgtttttcacaatcac
cacatctttctgggtgcaatcaacaagatttatgtcttaaatgaagatcttcataatgtt
tctgagtataagacgggacctgtgctggaacaccctgattgttctccgtgtcaggattgc
agtcacaaagccaacttatcaggtagtgtttggaaggataatgtcaataaagccttgctt
attgatacctactatgatgaccagctcattagttgtggcagtgtcaatcgagggacctgc
cagcgccatgtgtttcagcccaataatgctgctgatatacagtcacaagtttattgcata
tattccccacagatggatgaggagtccctccaatgtcctgactgtgtggtaagcacttta
gggaccaaagttctactgacagaaaaagaccgatttataaacttctttgtaggcaatacc
ataaattcttcttacgctgatcattcctcgcattcaatatctgttaggaggctaaaggaa
acacaagatggttttaaatttttgactgatcaatcctatattgatgttctacctgaattc
caagattcttaccctattaaatatatacatgcctttgaaagcagtgacttcatttatttt
ctgactgtacaaagagaaactctcgaatctcagacttttcacacacgaataatcaggttc
tgttccattgactctggattgcattcatacatggaaatgcctcttgaatgtattcttact
gagaagaggagaaagaggtcgccaagggaagaagtatttaatgttctacaagctgcatat
gtgagtaagcctggtgcacatctagctaggcaaataggcgttggacccaatgatgacatt
atctttggagtatttgcacaaagtaaaccagactcttcagaaccaatcaagagatcagca
gtctgcgcattcccaatcaaatttgtcaatgatttcttcaacagaattgtgaacaaaaat
aatgtgagatgtcttcagcacttttatgggaacaatcacaagcactgctttaataggaca
tttttaagaaactcatcaggttgtgaagcaagagatgatgaatataggacagaatttact
acaggcttgcaacgtatcgatttattcactggacaattcaagcaagttcttttaacatca
atatctacttttatcaaggaagacctaaccattgcaaaccttggaacatcagatggtcga
tttatgcaggttgtggtttctcggggacaatcaacccctcatgtgaattttcaattggat
tcccatcccgtttccccagaagtgattgttgagcatccactaaatgcagatggcttcaca
ctagttattactgggaaaaagataactaagatcccattgaatggcctaggttgtgaccat
tttaagtcctgcagccaatgtctctcagctcctccttttgtgcaatgtacctggtgtcat
aatcaatgtgtgaaatctaaagaatgtgtcactgaactagggaaccaagatatttgtctg
cctactatttatgagattctcccaactagtgcacccctagagggaggcacaacactgact
gtgtgtggctgggattttggattaagaaaaaataataaatttgattttagaaaaaccaaa
gttttcattggaaatgagagttgcatattgaatacaagtgagagcactacaaataagttg
aaatgtactgttggtcctgctgtgaacctgcatttcaatgtatccatcattatttcaaat
ggtcgagaaacaacaaaatttaattccttctcttatgtggatcctgtaataacaaatatt
tctccaagctatggtcccaaggctggtggtacagtacttactttaattgggaaatatcta
aacagtggaaattctagacgtatttcaatcggtggaaagccatgtattttaaaaagtgtg
tctcatagccttctagaatgttatactcctgcacaaaccattccaagtgagtaccccatt
aaaatgaaaattgacttagccaatcgagaagcctacagttttacatacaaagaggaccct
attgttcataaaatccatccaaccaaatcttttcttagtggaggaagcacaataacaggt
tttggaaaaaacctgaattctgctagcgtgcccaagatggtaataaatgtccctgaagta
ggaaggaacttcacagtggcatgtaagcatcgatctaattcagagataatctgttgttcg
actccttccttacaacagctaaatctgcaaccccccctggaaacaaaagctcttttcata
tttgatggtatccattccacttactttgatctcatttatgtccataatcctgtatttaag
ccttttgaaaagccagtgatgatctcaatgggcaatgaaaatgtactagaaattaaggga
aatgatattgaccctgaggcagtaaaaggtgaagtgttaaaagtgggaaataaaagctgt
gagaatatccgcttgaactctgaaacagtcttatgtacagtccccagtgacctgctgaaa
ctgaacagtgagctaaatatagagtggaagcaagcagtttcttctactgtccttggaaaa
gtgatagtacaaccagatcaaaatttcacaggactcattgttggagtggtcttgatatca
ttgttgctcttgtttttactgggcctttttctgtggctgaaaaagaggaagcagattaaa
gatctgggcagtgacttagttcgctatgatgcaagagtacacactcctcacttggacagg
cttgtaagtgcccgaagtgtgagccctaccacagaaatggtttcaaatgaatctgtagac
tacagagcaacttttccagaagatcagtttccacattcttctcagaatggatcctgcaga
caagctcattatcctctgacagatttgtcccccatcctaaccagtgcagattcagatata
tccagtccgctgcttcagaatcatgtccacattgatatcagcgccttaaatccagacctg
gtccaagctgttcaacatgtggttattgggccaaacagcctgattgtgcatttcaatgaa
atcataggaagagggcattttggatgtgtgtatcatgggaccttattggataatgatggc
aagaagattcattgtgctgtgaagtccttgaatagaattactgacataggagaggtttcc
caatttctgactgaagggatcatcatgaaagattttagtcatcccaatgtcctctcactt
ttgggaatctgccttcgtagtgaagggtccccattggtggtcctgccatatatgaaacat
ggagatcttcgaaacttcataagaaatgagactcataacccaacagtgaaagatcttatt
ggctttggtcttcaagtagcgaaaggcatgaaataccttgcaagcaaaaagtttgtccac
agagacttggctgcaagaaattgtatgctggatgaaaaattcactgtcaaggttgctgat
tttgggcttgccagagatatgtatgataaagaatattacagtgtacacaataaaacagga
gcaaaactgccagtgaagtggatggctttagaaagcttgcaaactcagaagtttactaca
aagtcagatgtgtggtcttttggagtgcttctctgggaactaatgactagaggagcacct
ccttatcctgatgttaatacctttgatataacagtttatttattgcaaggtcgaaggctt
ttgcaacctgaatactgcccagatccactgtatgaagttatgctaaaatgctggcaccca
aaagctgaaatgcgtccctctttctctgaactggtctcaaagatatcagtcatattctct
acatttattggagagcattatgttcacgtgaatgcaacctacgtcaatgtaaaatgtgtt
gctccttacccttcccttttgtcatcccaagacaacgttgacagggaggtggacacctga
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integrated database retrieval system
