KEGG   Sarcophilus harrisii (Tasmanian devil): 100927760Help
Entry
100927760         CDS       T02286                                 

Gene name
GAD1
Definition
(RefSeq) glutamate decarboxylase 1 isoform X1
  KO
K01580  glutamate decarboxylase [EC:4.1.1.15]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
shr00250  Alanine, aspartate and glutamate metabolism
shr00410  beta-Alanine metabolism
shr00430  Taurine and hypotaurine metabolism
shr00650  Butanoate metabolism
shr01100  Metabolic pathways
shr04727  GABAergic synapse
shr04940  Type I diabetes mellitus
Module
shr_M00027  GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    100927760 (GAD1)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    100927760 (GAD1)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    100927760 (GAD1)
   00430 Taurine and hypotaurine metabolism
    100927760 (GAD1)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    100927760 (GAD1)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100927760 (GAD1)
Enzymes [BR:shr01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     100927760 (GAD1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pyridoxal_deC Aminotran_5 Beta_elim_lyase SepSecS DegT_DnrJ_EryC1 OKR_DC_1
Motif
Other DBs
NCBI-GeneID: 100927760
NCBI-ProteinID: XP_003764000
Ensembl: ENSSHAG00000011468
LinkDB All DBs
Position
3
AA seq 594 aa AA seqDB search
MASSAPSSSSSSSNPGPDSNPTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRIVSAFKERQSSKNLISCENSEREARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLRKMREIIGWS
SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMSAVPKLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLETKILDAKKKGYVPLYVNATAGTTVYGAFDPIPEIA
DICHKYNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMGVLLQCSAILVRE
KGILQGCNQMCAGYLFQQDKQYDISYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQV
NKCLDLAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSDERREKLHKVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATKSDIDFLIEEIERLGQDL
NT seq 1785 nt NT seq  +upstreamnt  +downstreamnt
atggcttcttcggctccttcttcctcctcctcctcttccaacccgggcccggactctaac
cccaccaacctacgccctacaacttatgacacctggtgtggggtggcccatggatgtacc
agaaaactgggactcaagatatgcggcttcttgcaaaggaccaacagcctggaagagaag
agtcgaattgtgagtgccttcaaggagaggcaatcctcaaagaatctgatatcatgtgag
aatagtgagcgggaggcacggttccgtcgaactgagactgacttctccaacctgtttgca
agagatcttcttccagccaagaatggggaagagcaaactgtgcagttccttctggaagtg
gtggatatccttctcaactatgttcgaaagacatttgacagatcaaccaaggtgctggac
ttccatcacccacaccagttactggaaggaatggagggcttcaacctagagctatctgac
caccccgaatccttggagcagatccttgtggactgcagagatactctgaagtatggagtt
cgaacaggtcatcctcgatttttcaatcaactctctactggactggatataattggctta
gctggtgagtggctgacatcaactgctaataccaatatgtttacatatgaaattgcccca
gtgtttgtcctcatggagcaaataacacttaggaagatgcgagaaattattggatggtca
agtaaagatggtgatggcattttttcacctgggggtgccatatccaatatgtacagcatc
atggctgctcgatataagtacttcccagaagtcaaaaccaaaggcatgtcagctgttcct
aaactggtcctctttacctccgaacacagtcactattcaataaagaaagcgggggccgca
cttggctttggaacagacaatgtgattctgataaaatgcaatgaaagggggaaaatcatc
cccgctgacttggagacaaaaattcttgacgccaagaaaaagggatatgttcctctttat
gtcaatgcaaccgcaggcacgactgtgtatggagcttttgatccgatacctgagattgca
gatatatgtcacaaatataacctctggctgcatgttgatgctgcttggggaggaggtctc
ctcatgtccagaaagcaccgtcacaagctcaatggcattgaaagagccaattcagttacc
tggaaccctcataagatgatgggcgttctgttacaatgctctgccattctcgtgcgggaa
aagggcatactccaaggatgcaatcaaatgtgtgcaggttacctattccagcaagataag
cagtatgacatttcctatgacactggagacaaggccatccagtgtggccgccacgtggac
attttcaagttttggttgatgtggaaagctaagggcacagtgggatttgaaaatcaggtc
aacaagtgcctggatttagcagagtatctatatgccaaaattaaaaacagagaagaattt
gaaatggtttttgacggtgagcctgagcacacaaatgtttgcttctggtacattccacaa
agcctcaggggtgttccagacagcgatgaaagaagagaaaaacttcacaaggtggcaccg
aagatcaaagctctgatgatggaatctggaacaactatggttggatatcagcctcaggga
gacaaagccaacttcttccggatggtcatctcaaatccagcagccaccaagtctgacatc
gacttcctcattgaggaaatagaaagattggggcaggatctgtaa

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