Streptomyces laurentii: SLA_3241
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Entry
SLA_3241 CDS
T05205
Name
(GenBank) uroporphyrinogen-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
slau
Streptomyces laurentii
Pathway
slau00860
Porphyrin metabolism
slau01100
Metabolic pathways
slau01110
Biosynthesis of secondary metabolites
slau01120
Microbial metabolism in diverse environments
slau01240
Biosynthesis of cofactors
Module
slau_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
slau_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
slau00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SLA_3241
Enzymes [BR:
slau01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SLA_3241
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SLA_3241
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BAU84155
UniProt:
A0A160P0S1
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All DBs
Position
complement(3399102..3400520)
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AA seq
472 aa
AA seq
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MLRDPANLVMEAARGGKRVVRAVTGDPGLDGNAGAEMLACAAEGIPFEVVPGVATAVGVP
AYAGVPLRDAQGTDVRFVDARTADDRCWAEVGASECTVVVSTSLDSVAAAAGELVAAGRR
SDTPLTVTIGGTTTRQRTWTATLGTIAQVFKQGKVLPSPEGHRQAIAVVGERSAPAQRDQ
LAWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKG
LVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVGEQTAAALVDFGVKPDLV
PSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVR
ASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGL
RVDVLSPEPSVHKLAEALAEFGLRRRAAAREAGESVTRPSERRPGARRRRTT
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
gtgttgagggatcccgccaatcttgtcatggaggcagcgcgcggcggcaagcgggtcgtc
cgtgcggtgaccggcgaccccggcctcgacggcaacgccggcgccgagatgctcgcctgc
gccgccgagggcatcccgttcgaggtcgtccccggtgtcgccaccgccgtcggcgtgccc
gcgtacgccggcgtaccgctgcgcgacgcgcagggcaccgacgtccgcttcgtcgacgcc
cggaccgccgacgaccgctgctgggccgaggtcggcgcctccgagtgcaccgtcgtcgtg
tccacctccctggactcggtcgccgcggccgccggtgagctggtcgccgcgggccgccgg
tccgacaccccgctcaccgtcaccatcggcggtacgaccacgcgccagcgcacctggacc
gcgacgctgggcaccatcgcgcaggtcttcaagcagggcaaggtgctcccctcgcccgag
ggccaccgccaggccatagccgtggtcggcgagcgcagcgcccccgcgcagcgcgaccag
ctcgcgtggttcgagtccaagccgctgttcggctggcgcgtgctcgtcccgcgtaccaag
gagcaggccgcgtcgctctccgaccagctgcgttcctacggcgcggtgccgcacgaggtg
ccgaccatcgccgtcgagccgccgcgcaccccgcagcagatggagcgggccgtcaagggc
ctcgtcaccggacgctacgagtggatcgccttcacctcggtgaacgcggtcaaggcggtc
cgcgagaagttcgaggagtacgggctcgacgcccgtgccttcgccggcatcaaggtcgcc
gccgtcggcgagcagaccgccgccgcgctcgtcgacttcggcgtgaagccggacctcgtc
ccgagcggcgagcagtccgcggccggtcttcttgaggactggccgccgtacgacccggtc
ttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgcgaccgagacgctcgtc
gccggtctcatcgagctcgggtgggaggtcgacgacgtcaccgcctaccggaccgtgcgc
gcgtcgccgccgccggcggacacccgcgaggcgatcaagggcggcggcttcgacgcggtc
ctcttcacctcgtcgtcgaccgtgcggaacctcgtcggcatcgccggcaagccgcacaac
gtcaccgtcatcgcctgcatcggccccgcgaccgcgaagaccgcggaggagcacgggctg
cgggtcgacgtgctgtcgccggagccgtccgtgcacaagctggcggaggcgctggcggag
ttcgggctgcggcggcgtgcggccgcgcgggaggccggcgagtcggtgacgcggccgagt
gagcggcggccgggggcgcggcggcgtcgtacgacgtag
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