Streptomyces pluripotens: LK06_015340
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Entry
LK06_015340 CDS
T04845
Name
(GenBank) alpha-ketoacid dehydrogenase subunit beta
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
splu
Streptomyces pluripotens
Pathway
splu00280
Valine, leucine and isoleucine degradation
splu00640
Propanoate metabolism
splu00785
Lipoic acid metabolism
splu01100
Metabolic pathways
splu01110
Biosynthesis of secondary metabolites
splu01210
2-Oxocarboxylic acid metabolism
Module
splu_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
splu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LK06_015340
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LK06_015340
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LK06_015340
Enzymes [BR:
splu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LK06_015340
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
ARP71110
UniProt:
A0A221NZZ8
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Position
complement(3433390..3434367)
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AA seq
325 aa
AA seq
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MAEKMAMAKAINESLRRALEADPKVLVMGEDVGKLGGVFRVTDGLQKDFGESRVIDTPLA
ESGIVGTAIGLALRGYRPVVEIQFDGFVFPAYDQIVTQLAKMHARALGKVKMPVVIRIPY
GGGIGAVEHHSESPEALFAHVAGLKVVSPSNSSDAYWMMQQAIQSDDPVIYFEPKRRYWD
KAEVDAAAIPAPLHRAQVVREGADLTLAAYGPMVKLCQEVAAAAAEEGKSLEVLDLRSVS
PLDFDSIQASVEKTRRLVVVHEAPVFFGSGAEIAARITERCFYHLEAPVLRVGGYHAPYP
PARLEEEYLPDLDRVLDAVDRSLAY
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcagagaagatggcgatggccaaggccatcaacgagtcgctgcgacgtgccctggag
gccgaccccaaggtcctggtcatgggtgaggacgtcggcaagctcggcggcgtcttccgg
gtgacggacggcctgcagaaggacttcggggagagccgggtcatcgacaccccgctcgcc
gagtccggcatcgtcggcaccgcgatcggcctcgccctgcgcggctaccgcccagtggtg
gagattcagttcgacgggttcgtcttcccggcctacgaccagatcgtcacgcagctcgcg
aagatgcacgcgcgtgcgctgggcaaggtgaagatgccggtcgtcatccgcatcccctac
ggcggcggcatcggcgcggtcgagcaccactcggagtcgccggaggcgctcttcgcgcac
gtggcgggcctgaaggtggtctccccgtcgaactcctcggacgcctactggatgatgcag
caggccatccagagcgacgatccggtgatctacttcgagcccaagcggcgctactgggac
aaggccgaggtggacgcggcagcgatccccgccccgctgcacagggcacaggtcgtccga
gagggcgccgacctgaccctggcggcctatggcccgatggtgaagctgtgccaggaagtc
gcggcggcggcggccgaggagggcaagtccctggaggtcctggacctgcgctcggtgtct
ccgctggacttcgactcgatccaggcctcggtggagaagacccgccgtctcgtcgtcgtt
cacgaggcgccggtgttcttcggttccggcgcggagatcgccgcgcggatcaccgagcgg
tgcttctaccacctagaggctccggtgctccgggtgggcggctaccacgccccctacccg
ccggcccggctggaggaggagtacctgccggacctggaccgcgtgctcgacgccgtcgac
cgctcgctggcgtactga
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