Streptococcus pyogenes MGAS8232 (serotype M18): spyM18_2144
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Entry
spyM18_2144 CDS
T00079
Name
(GenBank) putative formate-tetrahydrofolate ligase
KO
K01938
formate--tetrahydrofolate ligase [EC:
6.3.4.3
]
Organism
spm
Streptococcus pyogenes MGAS8232 (serotype M18)
Pathway
spm00670
One carbon pool by folate
spm01100
Metabolic pathways
spm01120
Microbial metabolism in diverse environments
spm01200
Carbon metabolism
spm01240
Biosynthesis of cofactors
Module
spm_M00140
C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:
spm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
spyM18_2144
Enzymes [BR:
spm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.3 formate---tetrahydrofolate ligase
spyM18_2144
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Gene cluster
GFIT
Motif
Pfam:
FTHFS
CbiA
Motif
Other DBs
NCBI-ProteinID:
AAL98593
UniProt:
Q8NZ49
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All DBs
Position
1792911..1794584
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AA seq
557 aa
AA seq
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MVLSDIEIANSVTMEPISKVANQLGIDEEALCLYGKYKAKIDARQLVALKDKPDGKLILV
TAISPTPAGEGKTTTSVGLVDALSAIGKKAVIALREPSLGPVFGVKGGAAGGGHAQVVPM
EDINLHFTGDFHAIGVANNLLAALIDNHIHHGNSLGIDSRRITWKRVVDMNDRQLRHIVD
GLQGKVNGVPREDGYDITVASEIMAILCLSENISDLKARLEKIIIGYNYQGEPVTAKDLK
AGGALAALLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYGDYAVTEA
GFGADLGAEKFIDIKCRMSGLRPAAVVLVATIRALKMHGGVPKADLATENVQAVVDGLPN
LDKHLANIQDVYGLPVVVAINKFPLDTDAELQAVYDACDKRGVDVVISDVWANGGAGGRE
LAEKVVALAEQDNQFCFVYEEDDSIETKLTKIVTKVYGGKGIRLTPAAKRELADLERLSF
GNYPICMAKTQYSFSDDAKKLGAPTDFTVTISNLKVSAGAGFIVALTGAIMTMPGLPKVP
ASETIDIDEEGNITGLF
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggttttatcagatattgaaatagccaactctgtcactatggagcctatcagtaaggtt
gccaatcaattagggattgacgaggaagcgctctgtctctatggcaagtacaaggcaaaa
attgatgcccgtcaactggtcgccttaaaagacaaacctgatggcaaactcattcttgtc
actgctatctcaccaacaccagctggtgagggcaaaaccaccacttctgttggattggta
gatgctctttctgccattggaaaaaaagcagttattgcccttcgtgaaccttctcttggt
cctgtttttggggttaagggaggagctgctggcggtggccacgcgcaagttgtcccaatg
gaagacatcaaccttcactttacaggggactttcatgccatcggtgtcgccaacaactta
ttagctgccttgattgataaccacattcaccatggcaatagcctaggcattgattctaga
cgtatcacttggaaacgtgtggtggatatgaatgaccgccagcttcgtcatattgttgat
ggcttgcaaggcaaggtcaacggagtacctcgtgaagatggttatgacattaccgtcgcc
tctgaaatcatggcaatcctgtgcctatccgaaaatatctctgacctcaaagcccgcctt
gaaaaaatcatcatcggttacaattaccaaggcgaacctgtaacagctaaagacttgaaa
gctggtggtgccctagcagcactgctcaaggacgcgattcatcctaatctcgtgcaaacc
ctggaacacacaccagccctcattcacggtggcccatttgctaatatcgcccatggctgt
aatagtgtcctagccaccaaactagccttgaaatatggtgattatgccgttaccgaagct
ggatttggtgctgaccttggagctgaaaaattcattgacatcaaatgccgcatgtcaggc
cttcgtccagcagccgttgtcctagtagccactattcgtgcccttaaaatgcatgggggt
gtgccaaaagcagacctggctactgaaaatgttcaggccgttgtggatggtttacctaac
cttgacaaacatttggctaatatccaagacgtctatggccttccagttgtcgtggcgatc
aataaattcccgcttgataccgatgctgaattacaagctgtctatgatgcctgcgacaaa
cgtggcgttgacgttgtgatttctgatgtttgggcaaatggcggagctggtggccgtgaa
ttagctgaaaaagtcgtggcactagccgagcaagacaatcaattctgctttgtttatgag
gaagatgatagcattgaaaccaaactgactaaaatcgttaccaaggtttacggtggtaag
gggattagattgacccccgcagccaaacgtgaactggctgacttagaacgcctcagcttt
ggcaactacccaatttgcatggccaaaacccaatattccttctcagacgatgccaaaaaa
cttggcgcaccaactgactttacagtgactattagcaacctcaaagtgtccgcaggagca
ggctttatcgttgctctgacgggtgctatcatgaccatgcctggccttccaaaagtaccc
gccagcgaaacaattgatattgacgaggagggcaacatcacaggattattctaa
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