KEGG   Streptococcus pyogenes M1 476 (serotype M1): M1GAS476_1220Help
Entry
M1GAS476_1220     CDS       T02499                                 

Gene name
ddl
Definition
(GenBank) D-alanyl-alanine synthetase A
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
spym  Streptococcus pyogenes M1 476 (serotype M1)
Pathway
spym00473  D-Alanine metabolism
spym00550  Peptidoglycan biosynthesis
spym01100  Metabolic pathways
spym01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:spym00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00473 D-Alanine metabolism
    M1GAS476_1220 (ddl)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    M1GAS476_1220 (ddl)
 09160 Human Diseases
  09175 Drug resistance: Antimicrobial
   01502 Vancomycin resistance
    M1GAS476_1220 (ddl)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:spym01011]
    M1GAS476_1220 (ddl)
Enzymes [BR:spym01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     M1GAS476_1220 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:spym01011]
 Precursor biosynthesis
  Amino acid ligase
   M1GAS476_1220 (ddl)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID: BAM30550
UniProt: J7M861
LinkDB All DBs
Position
1:complement(1155104..1156150)
Genome map
AA seq 348 aa AA seqDB search
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIKTQQFSEKPS
ESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVM
SSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSV
GISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDF
YDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEMFDQRESHLI
NT seq 1047 nt NT seq  +upstreamnt  +downstreamnt
atgtccaaacaaacgttagttctattatacggaggccgctcagcagaacgtgaagtctca
gtgctttcagcagagagtgtgatgcgagcagtcaactatgataagttcttagtaaaaact
tattttattactcagatgggccaatttatcaaaactcagcaattttcagaaaagccatcg
gaatcagaacgcttgatgacaaatgagacgatagagctaactcaaaaaataaaaccaagt
gatatctatgaagaaggtgcagttgtatttcctgtattacatggacctatgggagaagat
ggctctatccaaggtttcttagaagtgcttagaatgccatatatagggactaatgtcatg
tcttctagcatagctatggataaaattactactaaacgtgtcttagaatcaattggaatt
ccacaagttgcctatactgtttatattgacggacaagatttggaggcttgtttagttgaa
actttagcaagacttacttttcctatcttcgtaaaaccagctaatatgggttcttctgtg
gggatttccaaagcccaaacaaaagtagaattaagaaaagcgattcagttagccctgacc
tatgacagtcgtgtcttgattgaacaaggcgtggttgcaagagaaattgaagttggtctc
cttggaaatgataaggttaaatcaactctaccaggagaagtaatcaaggacgttgatttt
tacgactaccaggcaaaatatgttgacaataagattacgatggccattccagcagatgta
gaccagagtattgtgacagaaatgcgttcttatgctgaagtagcctttaaagccttaggt
ggttgtgggttgtcccgttgtgactttttcttgacccaagatggacaggtttaccttaat
gaattaaacaccatgccaggctttacccaatggtctatgtatccactcttatgggaaaat
atgggattggcttatccagatttgattgaagagctggtgacactggcacaagaaatgttt
gaccagcgtgagagccacctgatttaa

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