Sus scrofa (pig): 100126861
Help
Entry
100126861 CDS
T01009
Gene name
AKT1
Definition
(RefSeq) RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01521
EGFR tyrosine kinase inhibitor resistance
ssc01522
Endocrine resistance
ssc01524
Platinum drug resistance
ssc04010
MAPK signaling pathway
ssc04012
ErbB signaling pathway
ssc04014
Ras signaling pathway
ssc04015
Rap1 signaling pathway
ssc04022
cGMP-PKG signaling pathway
ssc04024
cAMP signaling pathway
ssc04062
Chemokine signaling pathway
ssc04066
HIF-1 signaling pathway
ssc04068
FoxO signaling pathway
ssc04071
Sphingolipid signaling pathway
ssc04072
Phospholipase D signaling pathway
ssc04140
Autophagy - animal
ssc04150
mTOR signaling pathway
ssc04151
PI3K-Akt signaling pathway
ssc04152
AMPK signaling pathway
ssc04210
Apoptosis
ssc04211
Longevity regulating pathway
ssc04213
Longevity regulating pathway - multiple species
ssc04218
Cellular senescence
ssc04261
Adrenergic signaling in cardiomyocytes
ssc04370
VEGF signaling pathway
ssc04371
Apelin signaling pathway
ssc04380
Osteoclast differentiation
ssc04510
Focal adhesion
ssc04550
Signaling pathways regulating pluripotency of stem cells
ssc04611
Platelet activation
ssc04613
Neutrophil extracellular trap formation
ssc04620
Toll-like receptor signaling pathway
ssc04625
C-type lectin receptor signaling pathway
ssc04630
JAK-STAT signaling pathway
ssc04660
T cell receptor signaling pathway
ssc04662
B cell receptor signaling pathway
ssc04664
Fc epsilon RI signaling pathway
ssc04666
Fc gamma R-mediated phagocytosis
ssc04668
TNF signaling pathway
ssc04722
Neurotrophin signaling pathway
ssc04725
Cholinergic synapse
ssc04728
Dopaminergic synapse
ssc04910
Insulin signaling pathway
ssc04914
Progesterone-mediated oocyte maturation
ssc04915
Estrogen signaling pathway
ssc04917
Prolactin signaling pathway
ssc04919
Thyroid hormone signaling pathway
ssc04920
Adipocytokine signaling pathway
ssc04922
Glucagon signaling pathway
ssc04923
Regulation of lipolysis in adipocytes
ssc04926
Relaxin signaling pathway
ssc04929
GnRH secretion
ssc04931
Insulin resistance
ssc04932
Non-alcoholic fatty liver disease
ssc04933
AGE-RAGE signaling pathway in diabetic complications
ssc04935
Growth hormone synthesis, secretion and action
ssc04973
Carbohydrate digestion and absorption
ssc05010
Alzheimer disease
ssc05017
Spinocerebellar ataxia
ssc05132
Salmonella infection
ssc05135
Yersinia infection
ssc05142
Chagas disease
ssc05145
Toxoplasmosis
ssc05152
Tuberculosis
ssc05160
Hepatitis C
ssc05161
Hepatitis B
ssc05162
Measles
ssc05163
Human cytomegalovirus infection
ssc05164
Influenza A
ssc05165
Human papillomavirus infection
ssc05166
Human T-cell leukemia virus 1 infection
ssc05167
Kaposi sarcoma-associated herpesvirus infection
ssc05168
Herpes simplex virus 1 infection
ssc05169
Epstein-Barr virus infection
ssc05170
Human immunodeficiency virus 1 infection
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05210
Colorectal cancer
ssc05211
Renal cell carcinoma
ssc05212
Pancreatic cancer
ssc05213
Endometrial cancer
ssc05214
Glioma
ssc05215
Prostate cancer
ssc05218
Melanoma
ssc05220
Chronic myeloid leukemia
ssc05221
Acute myeloid leukemia
ssc05222
Small cell lung cancer
ssc05223
Non-small cell lung cancer
ssc05224
Breast cancer
ssc05225
Hepatocellular carcinoma
ssc05226
Gastric cancer
ssc05230
Central carbon metabolism in cancer
ssc05231
Choline metabolism in cancer
ssc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100126861 (AKT1)
04012 ErbB signaling pathway
100126861 (AKT1)
04014 Ras signaling pathway
100126861 (AKT1)
04015 Rap1 signaling pathway
100126861 (AKT1)
04370 VEGF signaling pathway
100126861 (AKT1)
04371 Apelin signaling pathway
100126861 (AKT1)
04630 JAK-STAT signaling pathway
100126861 (AKT1)
04668 TNF signaling pathway
100126861 (AKT1)
04066 HIF-1 signaling pathway
100126861 (AKT1)
04068 FoxO signaling pathway
100126861 (AKT1)
04072 Phospholipase D signaling pathway
100126861 (AKT1)
04071 Sphingolipid signaling pathway
100126861 (AKT1)
04024 cAMP signaling pathway
100126861 (AKT1)
04022 cGMP-PKG signaling pathway
100126861 (AKT1)
04151 PI3K-Akt signaling pathway
100126861 (AKT1)
04152 AMPK signaling pathway
100126861 (AKT1)
04150 mTOR signaling pathway
100126861 (AKT1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100126861 (AKT1)
09143 Cell growth and death
04210 Apoptosis
100126861 (AKT1)
04218 Cellular senescence
100126861 (AKT1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100126861 (AKT1)
04550 Signaling pathways regulating pluripotency of stem cells
100126861 (AKT1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100126861 (AKT1)
04613 Neutrophil extracellular trap formation
100126861 (AKT1)
04620 Toll-like receptor signaling pathway
100126861 (AKT1)
04625 C-type lectin receptor signaling pathway
100126861 (AKT1)
04660 T cell receptor signaling pathway
100126861 (AKT1)
04662 B cell receptor signaling pathway
100126861 (AKT1)
04664 Fc epsilon RI signaling pathway
100126861 (AKT1)
04666 Fc gamma R-mediated phagocytosis
100126861 (AKT1)
04062 Chemokine signaling pathway
100126861 (AKT1)
09152 Endocrine system
04910 Insulin signaling pathway
100126861 (AKT1)
04922 Glucagon signaling pathway
100126861 (AKT1)
04923 Regulation of lipolysis in adipocytes
100126861 (AKT1)
04920 Adipocytokine signaling pathway
100126861 (AKT1)
04929 GnRH secretion
100126861 (AKT1)
04915 Estrogen signaling pathway
100126861 (AKT1)
04914 Progesterone-mediated oocyte maturation
100126861 (AKT1)
04917 Prolactin signaling pathway
100126861 (AKT1)
04926 Relaxin signaling pathway
100126861 (AKT1)
04935 Growth hormone synthesis, secretion and action
100126861 (AKT1)
04919 Thyroid hormone signaling pathway
100126861 (AKT1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100126861 (AKT1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100126861 (AKT1)
09156 Nervous system
04725 Cholinergic synapse
100126861 (AKT1)
04728 Dopaminergic synapse
100126861 (AKT1)
04722 Neurotrophin signaling pathway
100126861 (AKT1)
09158 Development and regeneration
04380 Osteoclast differentiation
100126861 (AKT1)
09149 Aging
04211 Longevity regulating pathway
100126861 (AKT1)
04213 Longevity regulating pathway - multiple species
100126861 (AKT1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100126861 (AKT1)
05205 Proteoglycans in cancer
100126861 (AKT1)
05230 Central carbon metabolism in cancer
100126861 (AKT1)
05231 Choline metabolism in cancer
100126861 (AKT1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100126861 (AKT1)
09162 Cancer: specific types
05210 Colorectal cancer
100126861 (AKT1)
05212 Pancreatic cancer
100126861 (AKT1)
05225 Hepatocellular carcinoma
100126861 (AKT1)
05226 Gastric cancer
100126861 (AKT1)
05214 Glioma
100126861 (AKT1)
05221 Acute myeloid leukemia
100126861 (AKT1)
05220 Chronic myeloid leukemia
100126861 (AKT1)
05218 Melanoma
100126861 (AKT1)
05211 Renal cell carcinoma
100126861 (AKT1)
05215 Prostate cancer
100126861 (AKT1)
05213 Endometrial cancer
100126861 (AKT1)
05224 Breast cancer
100126861 (AKT1)
05222 Small cell lung cancer
100126861 (AKT1)
05223 Non-small cell lung cancer
100126861 (AKT1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100126861 (AKT1)
05017 Spinocerebellar ataxia
100126861 (AKT1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100126861 (AKT1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100126861 (AKT1)
04931 Insulin resistance
100126861 (AKT1)
04933 AGE-RAGE signaling pathway in diabetic complications
100126861 (AKT1)
09171 Infectious disease: bacterial
05132 Salmonella infection
100126861 (AKT1)
05135 Yersinia infection
100126861 (AKT1)
05152 Tuberculosis
100126861 (AKT1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100126861 (AKT1)
05170 Human immunodeficiency virus 1 infection
100126861 (AKT1)
05161 Hepatitis B
100126861 (AKT1)
05160 Hepatitis C
100126861 (AKT1)
05164 Influenza A
100126861 (AKT1)
05162 Measles
100126861 (AKT1)
05168 Herpes simplex virus 1 infection
100126861 (AKT1)
05163 Human cytomegalovirus infection
100126861 (AKT1)
05167 Kaposi sarcoma-associated herpesvirus infection
100126861 (AKT1)
05169 Epstein-Barr virus infection
100126861 (AKT1)
05165 Human papillomavirus infection
100126861 (AKT1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100126861 (AKT1)
05142 Chagas disease
100126861 (AKT1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100126861 (AKT1)
01524 Platinum drug resistance
100126861 (AKT1)
01522 Endocrine resistance
100126861 (AKT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
100126861 (AKT1)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100126861 (AKT1)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100126861 (AKT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_11
Seadorna_VP7
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
100126861
NCBI-ProteinID:
NP_001153248
UniProt:
C1PIG3
LinkDB
All DBs
Position
6
AA seq
480 aa
AA seq
DB search
MNDVAVVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQRESPLNNFSVAQC
RLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEEMMDF
RSGSPSENSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMEGVDSERRPHFPQFSYSASGTA
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgtggccgtcgtgaaggagggctggctgcacaaacgaggcgagtacatcaag
acgtggcggccgcggtacttcctcctcaagaacgacggcaccttcatcggctacaaggag
cggccgcaggacctggagcagcgcgagtcgcccctcaacaacttctccgtggcgcaatgc
cggctgatgaagacggagcggccgcggcccaacaccttcatcatccgctgcctgcagtgg
acgaccgtcatcgagcgaacgttccacgtggagacgccggaggagcgggaggagtggacg
accgccatccagacggtggccgacgggctcaagcggcaggaggaagagatgatggacttc
cggtcgggctcgcccagcgagaactccggggccgaggagatggaggtgtccctggctaag
cccaaacaccgcgtgaccatgaatgagttcgagtacctgaagctgctgggcaaaggcacc
ttcgggaaggtgatcctggtgaaggagaaggccacgggccgctactacgccatgaagatc
ctgaagaaggaggtcatcgtggccaaggacgaggtcgcccacacgctcacggagaaccgc
gtcctccagaactctcggcacccgttcctgacggccttgaagtactccttccagacccac
gaccgcctgtgcttcgtcatggagtacgccaacggcggcgagctcttcttccacctgtcc
cgggagcgggtgttccccgaggatcgggcccgcttctacggcgccgagatcgtgtcggcc
ttggactacctgcactccgagaagaacgtggtgtatcgggacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagatcactgacttcgggctctgcaaggagggcatc
aaggacggcgccaccatgaagaccttctgtgggacgcccgagtacctggcccccgaggtg
ctggaggacaacgactacggccgggcggtggactggtggggactgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagctcttcgagctc
atcctcatggaggagatccgcttcccgcgcacgctcagccccgaggccaagtccctgctc
tcagggctgctcaagaaggaccccaagcagcggctcggcgggggctctgaggatgccaag
gagatcatgcagcaccgtttcttcgccagcatcgtgtggcaggatgtgtatgagaagaag
ctcagcccaccgttcaagcctcaggtcacgtccgagacggacaccaggtatttcgacgag
gagttcacggcgcagatgatcaccatcacgccgcccgaccaagacgacagcatggagggc
gtggacagcgagcggaggcctcacttcccccagttctcctactcggccagcggcacggcc
tga
Sus scrofa (pig): 100127478
Help
Entry
100127478 CDS
T01009
Gene name
AKT2
Definition
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01521
EGFR tyrosine kinase inhibitor resistance
ssc01522
Endocrine resistance
ssc01524
Platinum drug resistance
ssc04010
MAPK signaling pathway
ssc04012
ErbB signaling pathway
ssc04014
Ras signaling pathway
ssc04015
Rap1 signaling pathway
ssc04022
cGMP-PKG signaling pathway
ssc04024
cAMP signaling pathway
ssc04062
Chemokine signaling pathway
ssc04066
HIF-1 signaling pathway
ssc04068
FoxO signaling pathway
ssc04071
Sphingolipid signaling pathway
ssc04072
Phospholipase D signaling pathway
ssc04140
Autophagy - animal
ssc04150
mTOR signaling pathway
ssc04151
PI3K-Akt signaling pathway
ssc04152
AMPK signaling pathway
ssc04210
Apoptosis
ssc04211
Longevity regulating pathway
ssc04213
Longevity regulating pathway - multiple species
ssc04218
Cellular senescence
ssc04261
Adrenergic signaling in cardiomyocytes
ssc04370
VEGF signaling pathway
ssc04371
Apelin signaling pathway
ssc04380
Osteoclast differentiation
ssc04510
Focal adhesion
ssc04550
Signaling pathways regulating pluripotency of stem cells
ssc04611
Platelet activation
ssc04613
Neutrophil extracellular trap formation
ssc04620
Toll-like receptor signaling pathway
ssc04625
C-type lectin receptor signaling pathway
ssc04630
JAK-STAT signaling pathway
ssc04660
T cell receptor signaling pathway
ssc04662
B cell receptor signaling pathway
ssc04664
Fc epsilon RI signaling pathway
ssc04666
Fc gamma R-mediated phagocytosis
ssc04668
TNF signaling pathway
ssc04722
Neurotrophin signaling pathway
ssc04725
Cholinergic synapse
ssc04728
Dopaminergic synapse
ssc04910
Insulin signaling pathway
ssc04914
Progesterone-mediated oocyte maturation
ssc04915
Estrogen signaling pathway
ssc04917
Prolactin signaling pathway
ssc04919
Thyroid hormone signaling pathway
ssc04920
Adipocytokine signaling pathway
ssc04922
Glucagon signaling pathway
ssc04923
Regulation of lipolysis in adipocytes
ssc04926
Relaxin signaling pathway
ssc04929
GnRH secretion
ssc04931
Insulin resistance
ssc04932
Non-alcoholic fatty liver disease
ssc04933
AGE-RAGE signaling pathway in diabetic complications
ssc04935
Growth hormone synthesis, secretion and action
ssc04973
Carbohydrate digestion and absorption
ssc05010
Alzheimer disease
ssc05017
Spinocerebellar ataxia
ssc05132
Salmonella infection
ssc05135
Yersinia infection
ssc05142
Chagas disease
ssc05145
Toxoplasmosis
ssc05152
Tuberculosis
ssc05160
Hepatitis C
ssc05161
Hepatitis B
ssc05162
Measles
ssc05163
Human cytomegalovirus infection
ssc05164
Influenza A
ssc05165
Human papillomavirus infection
ssc05166
Human T-cell leukemia virus 1 infection
ssc05167
Kaposi sarcoma-associated herpesvirus infection
ssc05168
Herpes simplex virus 1 infection
ssc05169
Epstein-Barr virus infection
ssc05170
Human immunodeficiency virus 1 infection
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05210
Colorectal cancer
ssc05211
Renal cell carcinoma
ssc05212
Pancreatic cancer
ssc05213
Endometrial cancer
ssc05214
Glioma
ssc05215
Prostate cancer
ssc05218
Melanoma
ssc05220
Chronic myeloid leukemia
ssc05221
Acute myeloid leukemia
ssc05222
Small cell lung cancer
ssc05223
Non-small cell lung cancer
ssc05224
Breast cancer
ssc05225
Hepatocellular carcinoma
ssc05226
Gastric cancer
ssc05230
Central carbon metabolism in cancer
ssc05231
Choline metabolism in cancer
ssc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100127478 (AKT2)
04012 ErbB signaling pathway
100127478 (AKT2)
04014 Ras signaling pathway
100127478 (AKT2)
04015 Rap1 signaling pathway
100127478 (AKT2)
04370 VEGF signaling pathway
100127478 (AKT2)
04371 Apelin signaling pathway
100127478 (AKT2)
04630 JAK-STAT signaling pathway
100127478 (AKT2)
04668 TNF signaling pathway
100127478 (AKT2)
04066 HIF-1 signaling pathway
100127478 (AKT2)
04068 FoxO signaling pathway
100127478 (AKT2)
04072 Phospholipase D signaling pathway
100127478 (AKT2)
04071 Sphingolipid signaling pathway
100127478 (AKT2)
04024 cAMP signaling pathway
100127478 (AKT2)
04022 cGMP-PKG signaling pathway
100127478 (AKT2)
04151 PI3K-Akt signaling pathway
100127478 (AKT2)
04152 AMPK signaling pathway
100127478 (AKT2)
04150 mTOR signaling pathway
100127478 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100127478 (AKT2)
09143 Cell growth and death
04210 Apoptosis
100127478 (AKT2)
04218 Cellular senescence
100127478 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100127478 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
100127478 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100127478 (AKT2)
04613 Neutrophil extracellular trap formation
100127478 (AKT2)
04620 Toll-like receptor signaling pathway
100127478 (AKT2)
04625 C-type lectin receptor signaling pathway
100127478 (AKT2)
04660 T cell receptor signaling pathway
100127478 (AKT2)
04662 B cell receptor signaling pathway
100127478 (AKT2)
04664 Fc epsilon RI signaling pathway
100127478 (AKT2)
04666 Fc gamma R-mediated phagocytosis
100127478 (AKT2)
04062 Chemokine signaling pathway
100127478 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
100127478 (AKT2)
04922 Glucagon signaling pathway
100127478 (AKT2)
04923 Regulation of lipolysis in adipocytes
100127478 (AKT2)
04920 Adipocytokine signaling pathway
100127478 (AKT2)
04929 GnRH secretion
100127478 (AKT2)
04915 Estrogen signaling pathway
100127478 (AKT2)
04914 Progesterone-mediated oocyte maturation
100127478 (AKT2)
04917 Prolactin signaling pathway
100127478 (AKT2)
04926 Relaxin signaling pathway
100127478 (AKT2)
04935 Growth hormone synthesis, secretion and action
100127478 (AKT2)
04919 Thyroid hormone signaling pathway
100127478 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100127478 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100127478 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
100127478 (AKT2)
04728 Dopaminergic synapse
100127478 (AKT2)
04722 Neurotrophin signaling pathway
100127478 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
100127478 (AKT2)
09149 Aging
04211 Longevity regulating pathway
100127478 (AKT2)
04213 Longevity regulating pathway - multiple species
100127478 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100127478 (AKT2)
05205 Proteoglycans in cancer
100127478 (AKT2)
05230 Central carbon metabolism in cancer
100127478 (AKT2)
05231 Choline metabolism in cancer
100127478 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100127478 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
100127478 (AKT2)
05212 Pancreatic cancer
100127478 (AKT2)
05225 Hepatocellular carcinoma
100127478 (AKT2)
05226 Gastric cancer
100127478 (AKT2)
05214 Glioma
100127478 (AKT2)
05221 Acute myeloid leukemia
100127478 (AKT2)
05220 Chronic myeloid leukemia
100127478 (AKT2)
05218 Melanoma
100127478 (AKT2)
05211 Renal cell carcinoma
100127478 (AKT2)
05215 Prostate cancer
100127478 (AKT2)
05213 Endometrial cancer
100127478 (AKT2)
05224 Breast cancer
100127478 (AKT2)
05222 Small cell lung cancer
100127478 (AKT2)
05223 Non-small cell lung cancer
100127478 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100127478 (AKT2)
05017 Spinocerebellar ataxia
100127478 (AKT2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100127478 (AKT2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100127478 (AKT2)
04931 Insulin resistance
100127478 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
100127478 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
100127478 (AKT2)
05135 Yersinia infection
100127478 (AKT2)
05152 Tuberculosis
100127478 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100127478 (AKT2)
05170 Human immunodeficiency virus 1 infection
100127478 (AKT2)
05161 Hepatitis B
100127478 (AKT2)
05160 Hepatitis C
100127478 (AKT2)
05164 Influenza A
100127478 (AKT2)
05162 Measles
100127478 (AKT2)
05168 Herpes simplex virus 1 infection
100127478 (AKT2)
05163 Human cytomegalovirus infection
100127478 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
100127478 (AKT2)
05169 Epstein-Barr virus infection
100127478 (AKT2)
05165 Human papillomavirus infection
100127478 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100127478 (AKT2)
05142 Chagas disease
100127478 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100127478 (AKT2)
01524 Platinum drug resistance
100127478 (AKT2)
01522 Endocrine resistance
100127478 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
100127478 (AKT2)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100127478 (AKT2)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100127478 (AKT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
100127478
NCBI-ProteinID:
NP_001243708
Ensembl:
ENSSSCG00000002989
Vega:
OTTSUSG00000002304
UniProt:
G9BWQ2
LinkDB
All DBs
Position
6
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGAGEDPM
DYKCGSPSDSSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLTVNWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaatgaggtgtctgtcatcaaagaaggctggctccacaagcgtggtgaatacatcaag
acctggaggccccggtacttcctgctgaagagtgacggctccttcattggctataaggag
cggcccgaggcccccgaccagaccctgccccccttaaacaacttctccgtagcagaatgc
cagctgatgaagaccgagagacctcggcccaacacctttgtcatacgctgcctgcagtgg
accacagtcatcgagaggaccttccatgtggactccccggatgagagggaggagtggatg
cgggccatccagatggttgccaacagcctcaagcagcggggcgcaggtgaggaccccatg
gactacaagtgtggctcccccagtgactcctctgctgctgaggagatggaagtggcagtg
agcaaggctcgggccaaggtgaccatgaacgacttcgactatctcaagctcctgggcaag
ggcacgttcggcaaagtcatcctggtgcgcgagaaggccaccggccgctactacgccatg
aagatcctgcggaaggaggttatcatcgccaaggatgaagtcgcccacacggtcaccgag
agccgggttctccagaacaccaggcacccgttcctcaccgcgctgaagtacgccttccag
acccacgaccgcctgtgcttcgtgatggagtacgccaacggtggcgagctgtttttccac
ctgtcccgggagcgcgtcttcacggaggagcgggcccgtttctacggcgcggagattgtc
tcggctctggagtacctgcactcgagggacgtggtgtaccgcgacatcaagctggaaaac
ctcatgctggacaaagacggccacatcaagatcacggacttcggcctgtgcaaagagggc
atcagtgatggggccaccatgaaaaccttctgtgggacccccgaatacctggcacccgag
gtgctggaggacaacgactacggccgggccgtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccgcttcccgcgcacgctcagccccgaggccaagtccttg
cttgcggggctgcttaagaaggacccaaagcagaggctcggcggggggcccagcgatgcc
aaggaggtcatggagcacaggttcttcctcaccgtcaactggcaggacgtggtacagaag
aagctcctgccacccttcaaacctcaggtcacatctgaggtcgacactcggtactttgac
gatgaattcaccgcccaatccatcacaatcacgcccccggaccgctatgacagcctgggc
tcgctcgaactggaccagcggacccacttcccccagttctcctactcggccagcatccgg
gagtga
Sus scrofa (pig): 100513811
Help
Entry
100513811 CDS
T01009
Gene name
AKT3
Definition
(RefSeq) RAC-gamma serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01521
EGFR tyrosine kinase inhibitor resistance
ssc01522
Endocrine resistance
ssc01524
Platinum drug resistance
ssc04010
MAPK signaling pathway
ssc04012
ErbB signaling pathway
ssc04014
Ras signaling pathway
ssc04015
Rap1 signaling pathway
ssc04022
cGMP-PKG signaling pathway
ssc04024
cAMP signaling pathway
ssc04062
Chemokine signaling pathway
ssc04066
HIF-1 signaling pathway
ssc04068
FoxO signaling pathway
ssc04071
Sphingolipid signaling pathway
ssc04072
Phospholipase D signaling pathway
ssc04140
Autophagy - animal
ssc04150
mTOR signaling pathway
ssc04151
PI3K-Akt signaling pathway
ssc04152
AMPK signaling pathway
ssc04210
Apoptosis
ssc04211
Longevity regulating pathway
ssc04213
Longevity regulating pathway - multiple species
ssc04218
Cellular senescence
ssc04261
Adrenergic signaling in cardiomyocytes
ssc04370
VEGF signaling pathway
ssc04371
Apelin signaling pathway
ssc04380
Osteoclast differentiation
ssc04510
Focal adhesion
ssc04550
Signaling pathways regulating pluripotency of stem cells
ssc04611
Platelet activation
ssc04613
Neutrophil extracellular trap formation
ssc04620
Toll-like receptor signaling pathway
ssc04625
C-type lectin receptor signaling pathway
ssc04630
JAK-STAT signaling pathway
ssc04660
T cell receptor signaling pathway
ssc04662
B cell receptor signaling pathway
ssc04664
Fc epsilon RI signaling pathway
ssc04666
Fc gamma R-mediated phagocytosis
ssc04668
TNF signaling pathway
ssc04722
Neurotrophin signaling pathway
ssc04725
Cholinergic synapse
ssc04728
Dopaminergic synapse
ssc04910
Insulin signaling pathway
ssc04914
Progesterone-mediated oocyte maturation
ssc04915
Estrogen signaling pathway
ssc04917
Prolactin signaling pathway
ssc04919
Thyroid hormone signaling pathway
ssc04920
Adipocytokine signaling pathway
ssc04922
Glucagon signaling pathway
ssc04923
Regulation of lipolysis in adipocytes
ssc04926
Relaxin signaling pathway
ssc04929
GnRH secretion
ssc04931
Insulin resistance
ssc04932
Non-alcoholic fatty liver disease
ssc04933
AGE-RAGE signaling pathway in diabetic complications
ssc04935
Growth hormone synthesis, secretion and action
ssc04973
Carbohydrate digestion and absorption
ssc05010
Alzheimer disease
ssc05017
Spinocerebellar ataxia
ssc05132
Salmonella infection
ssc05135
Yersinia infection
ssc05142
Chagas disease
ssc05145
Toxoplasmosis
ssc05152
Tuberculosis
ssc05160
Hepatitis C
ssc05161
Hepatitis B
ssc05162
Measles
ssc05163
Human cytomegalovirus infection
ssc05164
Influenza A
ssc05165
Human papillomavirus infection
ssc05166
Human T-cell leukemia virus 1 infection
ssc05167
Kaposi sarcoma-associated herpesvirus infection
ssc05168
Herpes simplex virus 1 infection
ssc05169
Epstein-Barr virus infection
ssc05170
Human immunodeficiency virus 1 infection
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05210
Colorectal cancer
ssc05211
Renal cell carcinoma
ssc05212
Pancreatic cancer
ssc05213
Endometrial cancer
ssc05214
Glioma
ssc05215
Prostate cancer
ssc05218
Melanoma
ssc05220
Chronic myeloid leukemia
ssc05221
Acute myeloid leukemia
ssc05222
Small cell lung cancer
ssc05223
Non-small cell lung cancer
ssc05224
Breast cancer
ssc05225
Hepatocellular carcinoma
ssc05226
Gastric cancer
ssc05230
Central carbon metabolism in cancer
ssc05231
Choline metabolism in cancer
ssc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ssc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100513811 (AKT3)
04012 ErbB signaling pathway
100513811 (AKT3)
04014 Ras signaling pathway
100513811 (AKT3)
04015 Rap1 signaling pathway
100513811 (AKT3)
04370 VEGF signaling pathway
100513811 (AKT3)
04371 Apelin signaling pathway
100513811 (AKT3)
04630 JAK-STAT signaling pathway
100513811 (AKT3)
04668 TNF signaling pathway
100513811 (AKT3)
04066 HIF-1 signaling pathway
100513811 (AKT3)
04068 FoxO signaling pathway
100513811 (AKT3)
04072 Phospholipase D signaling pathway
100513811 (AKT3)
04071 Sphingolipid signaling pathway
100513811 (AKT3)
04024 cAMP signaling pathway
100513811 (AKT3)
04022 cGMP-PKG signaling pathway
100513811 (AKT3)
04151 PI3K-Akt signaling pathway
100513811 (AKT3)
04152 AMPK signaling pathway
100513811 (AKT3)
04150 mTOR signaling pathway
100513811 (AKT3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100513811 (AKT3)
09143 Cell growth and death
04210 Apoptosis
100513811 (AKT3)
04218 Cellular senescence
100513811 (AKT3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100513811 (AKT3)
04550 Signaling pathways regulating pluripotency of stem cells
100513811 (AKT3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100513811 (AKT3)
04613 Neutrophil extracellular trap formation
100513811 (AKT3)
04620 Toll-like receptor signaling pathway
100513811 (AKT3)
04625 C-type lectin receptor signaling pathway
100513811 (AKT3)
04660 T cell receptor signaling pathway
100513811 (AKT3)
04662 B cell receptor signaling pathway
100513811 (AKT3)
04664 Fc epsilon RI signaling pathway
100513811 (AKT3)
04666 Fc gamma R-mediated phagocytosis
100513811 (AKT3)
04062 Chemokine signaling pathway
100513811 (AKT3)
09152 Endocrine system
04910 Insulin signaling pathway
100513811 (AKT3)
04922 Glucagon signaling pathway
100513811 (AKT3)
04923 Regulation of lipolysis in adipocytes
100513811 (AKT3)
04920 Adipocytokine signaling pathway
100513811 (AKT3)
04929 GnRH secretion
100513811 (AKT3)
04915 Estrogen signaling pathway
100513811 (AKT3)
04914 Progesterone-mediated oocyte maturation
100513811 (AKT3)
04917 Prolactin signaling pathway
100513811 (AKT3)
04926 Relaxin signaling pathway
100513811 (AKT3)
04935 Growth hormone synthesis, secretion and action
100513811 (AKT3)
04919 Thyroid hormone signaling pathway
100513811 (AKT3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100513811 (AKT3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100513811 (AKT3)
09156 Nervous system
04725 Cholinergic synapse
100513811 (AKT3)
04728 Dopaminergic synapse
100513811 (AKT3)
04722 Neurotrophin signaling pathway
100513811 (AKT3)
09158 Development and regeneration
04380 Osteoclast differentiation
100513811 (AKT3)
09149 Aging
04211 Longevity regulating pathway
100513811 (AKT3)
04213 Longevity regulating pathway - multiple species
100513811 (AKT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100513811 (AKT3)
05205 Proteoglycans in cancer
100513811 (AKT3)
05230 Central carbon metabolism in cancer
100513811 (AKT3)
05231 Choline metabolism in cancer
100513811 (AKT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100513811 (AKT3)
09162 Cancer: specific types
05210 Colorectal cancer
100513811 (AKT3)
05212 Pancreatic cancer
100513811 (AKT3)
05225 Hepatocellular carcinoma
100513811 (AKT3)
05226 Gastric cancer
100513811 (AKT3)
05214 Glioma
100513811 (AKT3)
05221 Acute myeloid leukemia
100513811 (AKT3)
05220 Chronic myeloid leukemia
100513811 (AKT3)
05218 Melanoma
100513811 (AKT3)
05211 Renal cell carcinoma
100513811 (AKT3)
05215 Prostate cancer
100513811 (AKT3)
05213 Endometrial cancer
100513811 (AKT3)
05224 Breast cancer
100513811 (AKT3)
05222 Small cell lung cancer
100513811 (AKT3)
05223 Non-small cell lung cancer
100513811 (AKT3)
09164 Neurodegenerative disease
05010 Alzheimer disease
100513811 (AKT3)
05017 Spinocerebellar ataxia
100513811 (AKT3)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100513811 (AKT3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100513811 (AKT3)
04931 Insulin resistance
100513811 (AKT3)
04933 AGE-RAGE signaling pathway in diabetic complications
100513811 (AKT3)
09171 Infectious disease: bacterial
05132 Salmonella infection
100513811 (AKT3)
05135 Yersinia infection
100513811 (AKT3)
05152 Tuberculosis
100513811 (AKT3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100513811 (AKT3)
05170 Human immunodeficiency virus 1 infection
100513811 (AKT3)
05161 Hepatitis B
100513811 (AKT3)
05160 Hepatitis C
100513811 (AKT3)
05164 Influenza A
100513811 (AKT3)
05162 Measles
100513811 (AKT3)
05168 Herpes simplex virus 1 infection
100513811 (AKT3)
05163 Human cytomegalovirus infection
100513811 (AKT3)
05167 Kaposi sarcoma-associated herpesvirus infection
100513811 (AKT3)
05169 Epstein-Barr virus infection
100513811 (AKT3)
05165 Human papillomavirus infection
100513811 (AKT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100513811 (AKT3)
05142 Chagas disease
100513811 (AKT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100513811 (AKT3)
01524 Platinum drug resistance
100513811 (AKT3)
01522 Endocrine resistance
100513811 (AKT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
100513811 (AKT3)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100513811 (AKT3)
Protein kinases [BR:
ssc01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100513811 (AKT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
FTA2
PH_11
Motif
Other DBs
NCBI-GeneID:
100513811
NCBI-ProteinID:
NP_001243075
Ensembl:
ENSSSCG00000010872
Vega:
OTTSUSG00000000913
UniProt:
A0A4X1T5S8
G9BWQ3
LinkDB
All DBs
Position
10
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccattgtgaaggaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtagcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtcttcagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagaatggacagaa
gctatccaggctgtagcagacagacttcagaggcaagaggaggagagaatgaattgtagt
ccaacttcacaaattgataatataggagaggaagagatggatgcttctacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcactttcggg
aaagttattttggttcgagagaaggcgagtgggaaatactatgctatgaagattctgaaa
aaagaagttattattgccaaggatgaagtggcacacactttaactgaaagcagagtatta
aagaacactagacatccttttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgggatctcaagttggagaatctgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacgttctgtggtacaccagaatatctggcaccagaggtgttagaagat
aatgactatggccgagccgtggattggtggggccttggggttgtcatgtatgaaatgatg
tgtgggaggttacctttctacaaccaggatcacgagaaactttttgaactaattctaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaggagattatg
aggcacagtttcttctctggagtaaactggcaagatgtatatgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagacaccagatattttgatgaagaatttaca
gctcagactattacaataacaccacctgaaaaatatgatgaggacggaatggactgcatg
gacaatgagaggcggccgcacttccctcagttttcctactctgcaagtggacgagaataa
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integrated database retrieval system
