KEGG   Sus scrofa (pig): 100511026
Entry
100511026         CDS       T01009                                 

Gene name
GAB1
Definition
(RefSeq) LOW QUALITY PROTEIN: GRB2-associated-binding protein 1
  KO
K09593  GRB2-associated-binding protein 1
Organism
ssc  Sus scrofa (pig)
Pathway
ssc01521  EGFR tyrosine kinase inhibitor resistance
ssc04012  ErbB signaling pathway
ssc04014  Ras signaling pathway
ssc04072  Phospholipase D signaling pathway
ssc04722  Neurotrophin signaling pathway
ssc05100  Bacterial invasion of epithelial cells
ssc05205  Proteoglycans in cancer
ssc05211  Renal cell carcinoma
ssc05225  Hepatocellular carcinoma
ssc05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100511026 (GAB1)
   04014 Ras signaling pathway
    100511026 (GAB1)
   04072 Phospholipase D signaling pathway
    100511026 (GAB1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    100511026 (GAB1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100511026 (GAB1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    100511026 (GAB1)
   05226 Gastric cancer
    100511026 (GAB1)
   05211 Renal cell carcinoma
    100511026 (GAB1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    100511026 (GAB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100511026 (GAB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:ssc04990]
    100511026 (GAB1)
Domain-containing proteins not elsewhere classified [BR:ssc04990]
 Pleckstrin homology (PH) domain-containing proteins
  Grb-2 associated binder (Gab) family proteins
   100511026 (GAB1)
SSDB
Motif
Pfam: PH PH_11 PH_9 PH_8 PH_3 Ciart PH_13
Other DBs
NCBI-GeneID: 100511026
NCBI-ProteinID: XP_003129225
Ensembl: ENSSSCG00000009048
Vega: OTTSUSG00000000902
UniProt: A0A480ZFM5
LinkDB
Position
8
AA seq 724 aa
MSGGEVVCSGWLRKSPPEKKLKRYAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRII
DLNLCQQVDAGLTFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPT
EEDPVKPPGSSLPAPADLPLAINAAPPSAQVDASSAAPPPPYQLISLPPHLETLGIQEDP
QDYLLLINCQSKKPEPTRMHPDAAKPTSSETDCNDNVPSHKNPTSSQSKHGVNGFFQQQM
MYDSPPSRAPSXSVDSSLYNLPRSFSHDVLPKASPSSTEADGELYVFNTPSGTASLETQM
RHVSMSYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPAHDRSPVETC
SVPRAASDTDSSYCIPTAGVPPSRSNTISTVDLNKLRKDASSQDCYDIPRTLPSDRSSSL
EGFPNPFKIKNVLTVGSISSEELDENYVPMNPNSPPRQHSRSFTEPMQEANYVPMTPGTF
DFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKGQSPKILRPKPH
GLERTDSQTIGDFATRRKAKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPLSPRP
DSVHSTTSSSDSHDSEENYVPMNPNLSSEDSNLFGSNSLDGGSSPMIKPKGDKQVEYLDL
DLDTGKSTPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPA
KNVK
NT seq 2175 nt   +upstreamnt  +downstreamnt
atgagcggcggcgaagtggtctgctcgggatggctccgcaagtcccccccggagaaaaag
ttgaagcgttatgcatggaagaggagatggtttgtgctacgaagtggccgtttgactggc
gatccagatgtcttggaatattacaaaaatgatcatgccaagaagcctatccgtattatt
gatttaaatttatgtcagcaagttgatgctggattgacatttaacaaaaaagagtttgaa
aacagctacatttttgatatcaacactatcgaccggattttctacttggtagcagacagt
gaagaggagatgaataagtgggttcgttgtatttgtgacatctgtgggtttaatcctaca
gaagaagatcctgtgaagccacccggcagctccttaccagcaccagctgatttaccatta
gcgataaatgcagcaccaccgtccgcccaggtggacgcctcctctgctgctccgcctcct
ccctatcagctaatcagccttccaccacacctggaaactcttggcatccaggaggatcct
caagactacctcttgctaatcaactgtcaaagcaagaagccagaacccaccagaatgcac
cctgacgctgccaaacccacctcttcggagacagactgcaatgataacgtcccttctcat
aaaaaccccacttcctcccagagcaaacatggagtgaacggcttttttcagcagcagatg
atgtacgactctccaccgtctcgagccccgtcgntttctgtagactccagcctttacaac
ctgcccaggagtttctcccacgatgttctgcccaaggcgtctccctcgagcacggaagca
gacggagaactctacgtattcaacacgccatcggggaccgcgagcttagagacccaaatg
aggcatgtgtccatgagttatgacattcctcccacgccgggtaatacttaccagattccg
cgaacatttccagaaggaaccttggggcagacgtcaaagctggacactattccagatatt
cctccacctcggccaccaaagccacacccggctcacgatcggtctcctgtggaaacatgt
agcgtcccacgcgcggcctcggacactgacagcagttactgtatcccgaccgcgggggtg
cctccgtcccgtagcaataccatttccaccgtggatctgaacaaactgcggaaagatgct
agttctcaagactgctatgatattccacgaacacttccaagtgatagatctagttccctc
gaaggcttccctaacccctttaaaatcaaaaatgtgttgacagtgggaagtatatcaagt
gaagaactggatgaaaattacgtcccaatgaatcccaactctccgccccggcaacattcc
cgcagttttacggaaccaatgcaggaagcaaattacgtgccaatgactccagggaccttt
gatttttcttcatttggaatgcaagttcctcctcctgcacacatgggcttcaggtccagc
cccaaaacccctcccagaaggccagttcctgttgcagactgtgaaccaccccccgtggat
cggaatctcaagccagacagaaaaggtcaaagtcctaaaattttaagacccaaaccccat
ggtttagagcgaactgattcacaaaccataggtgactttgctacaagaagaaaggccaag
ccagcacctttagaaataaaaccattgccagaatgggaagaattacaggccccggttaga
tctcccatcaccaggagttttgctcgagactcctccaggttccccctgtctccccggcca
gattcagtgcacagcacgacgtccagcagcgactcgcacgacagcgaagagaattatgtt
cccatgaacccaaacctgtccagtgaagactcaaatctcttcggcagtaatagtcttgat
ggaggaagcagcccaatgatcaaacccaaaggagacaaacaagtggaatacttagatcta
gatttagatactgggaagtccacaccaccacgtaagcaaaagagcagcggctcaggcagc
agtgtagctgacgagagagtggactatgtcgtggttgaccaacagaagaccctggctctg
aagagcacccgggaggcctggacggatgggaggcagtccacagagtctgaaacaccagcc
aagaatgtgaagtaa

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