Sus scrofa (pig): 100516641
Entry
100516641 CDS
T01009
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2 precursor
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01521
EGFR tyrosine kinase inhibitor resistance
ssc01522
Endocrine resistance
ssc01524
Platinum drug resistance
ssc04010
MAPK signaling pathway
ssc04012
ErbB signaling pathway
ssc04020
Calcium signaling pathway
ssc04066
HIF-1 signaling pathway
ssc04151
PI3K-Akt signaling pathway
ssc04510
Focal adhesion
ssc04520
Adherens junction
ssc04530
Tight junction
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05206
MicroRNAs in cancer
ssc05212
Pancreatic cancer
ssc05213
Endometrial cancer
ssc05215
Prostate cancer
ssc05219
Bladder cancer
ssc05223
Non-small cell lung cancer
ssc05224
Breast cancer
ssc05226
Gastric cancer
ssc05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100516641 (ERBB2)
04012 ErbB signaling pathway
100516641 (ERBB2)
04066 HIF-1 signaling pathway
100516641 (ERBB2)
04020 Calcium signaling pathway
100516641 (ERBB2)
04151 PI3K-Akt signaling pathway
100516641 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100516641 (ERBB2)
04520 Adherens junction
100516641 (ERBB2)
04530 Tight junction
100516641 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100516641 (ERBB2)
05206 MicroRNAs in cancer
100516641 (ERBB2)
05205 Proteoglycans in cancer
100516641 (ERBB2)
05230 Central carbon metabolism in cancer
100516641 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100516641 (ERBB2)
05226 Gastric cancer
100516641 (ERBB2)
05219 Bladder cancer
100516641 (ERBB2)
05215 Prostate cancer
100516641 (ERBB2)
05213 Endometrial cancer
100516641 (ERBB2)
05224 Breast cancer
100516641 (ERBB2)
05223 Non-small cell lung cancer
100516641 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100516641 (ERBB2)
01524 Platinum drug resistance
100516641 (ERBB2)
01522 Endocrine resistance
100516641 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
100516641 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ssc04147
]
100516641 (ERBB2)
04090 CD molecules [BR:
ssc04090
]
100516641 (ERBB2)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100516641 (ERBB2)
Protein kinases [BR:
ssc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100516641 (ERBB2)
Exosome [BR:
ssc04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100516641 (ERBB2)
CD molecules [BR:
ssc04090
]
Proteins
100516641 (ERBB2)
SSDB
Motif
Pfam:
Pkinase_Tyr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Haspin_kinase
Other DBs
NCBI-GeneID:
100516641
NCBI-ProteinID:
NP_001302542
Ensembl:
ENSSSCG00000017497
Vega:
OTTSUSG00000002335
UniProt:
A0A0D4CYJ6
LinkDB
Position
12
AA seq
1255 aa
MELAAWCRWGLLLALLPPGAASTQVCTGTDMKLQLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANANLFFLQEIQEVQGYVLIAHNRVSRVPLQRLRIVRGTQLFEDRYALAVLDNG
DLLESATPAAGAAAEGLQELQLQSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNPLT
TVAVEANRSRACPPCSPACKASHCWGESSKDCQSLTRTICAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACFHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCAQVCYGLGIEHLREVRAVTSAN
IQEFAGCRKIFGSLAFLPESFEGDPASSTAPLQPEQLRVFETLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNARLCFVHTV
PWDQLFRNPHQALLHSANRPEEECVGEGLTCYQLCAHGHCWGPGPTQCVNCSQFLRGQEC
VKECRVQQGHPREYVKDRYCLPCHPECQPQNGSDTCFGSEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEDGMCQPCPINCTHSCVDLDDKGCPAEQRASPASSIIAGVVG
VLLAAVIGVVFGTLIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSTSTRSGGGELTLGLEASEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQNLPQHDSSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPLPPPRPTGATLERPKTLSPGRNGVVKDVFAFGAAVENPEYLAPR
GRAPSQNHPSPAFSPAFDNLYYWDQDPSDRGALPSTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgagcacccaagtgtgcaccggcacagacatgaagctgcagctgccagccagtcctgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtacagggtaacctg
gagctcacctacctgccggctaatgccaacctcttcttcttgcaggagatccaggaggtg
cagggctacgtgcttatcgctcacaaccgagtgagtcgggtcccgctgcagaggctgcga
atcgtgcgaggtacccagctctttgaagacagatatgccctggctgtgctggacaatgga
gaccttctggaaagtgccacccctgctgcgggtgctgccgcagaagggctgcaggagctg
cagctgcaaagcctcacagagatcctgaagggaggagtcttgatccagcggaacccccag
ctctgccaccaggacacgattctgtggaaggacatcttccacaagaacaaccccctgacc
acagtggcggtagaagccaaccgctcccgggcctgcccaccctgttctccagcttgtaaa
gcttcccactgctggggagaaagttccaaggactgtcagagcttgacgcgaaccatctgt
gccggtggctgtgcccgctgtaagggcccgctgcccaccgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcttccacttcaaccac
agcggcatctgtgagctgcattgcccggccctggtcacctacaacacagacaccttcgag
tccatgcccaaccccgagggccgttacacctttggcgccagctgcgtgaccgcctgtcct
tacaactacctgtctacggacgtgggatcctgcaccctggtttgtcccccgaacaaccaa
gaggtgacagctgaggacggaacgcagcggtgtgagaaatgcagcaagccctgtgcccaa
gtgtgctacggtctgggcatagaacacctgcgggaggtgagggcggtcaccagcgccaat
atccaggagtttgctggctgcaggaagatctttgggagcctggcatttctgccagagagc
tttgagggggacccagcctccagcactgcccccctacagcctgagcagctcagagtgttt
gagactctggaggagatcacaggttacctgtacatctccgcttggccagatagcctgcct
gacctcagtgttttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcgctgcgggag
ctgggcagcgggctggccctcatccaccgcaacgcccgcctctgcttcgtgcatacggtg
ccctgggaccagctcttccggaaccctcaccaggccctgctccacagtgccaaccggcca
gaggaggagtgcgtgggcgagggcctgacctgctaccagctgtgcgcacacgggcactgc
tggggtccagggcccacccagtgcgtaaactgcagccagttccttcggggccaagagtgc
gtgaaggagtgccgagtacagcaggggcacccccgggagtacgtgaaggacaggtactgt
ctgccgtgccaccccgagtgtcagccccagaatggctccgacacctgctttggctcggag
gctgaccagtgtgtggcttgcgcccactacaaggatccccccttctgcgtggctcgttgc
cccagtggtgtgaagcctgacctctccttcatgcccatctggaagttcccggatgaggat
ggcatgtgccagccgtgccccatcaactgcacccactcctgtgtggacctggacgacaag
ggctgccctgcagagcagagagccagccccgcgtcgtccatcattgccggcgtggtgggc
gttctgctggccgccgtcataggggtggtctttggcaccctaatcaaacgaaggcgacag
aagatccgcaagtacacgatgcggaggctgctgcaggaaacggagctggtggagcccctg
acgcccagcggggcgatgcctaatcaggctcagatgcgcatcttgaaagagacggagctg
aggaaggtgaaggtgcttggatctggcgcttttggcacagtctacaagggcatctggatc
cccgatggggaaaatgtgaaaattccagtggccatcaaggtgttgagggaaaacacgtcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggtgtaggctccccg
tatgtgtcccgcctcctgggcatctgcctgacatccacggtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgagaacaccgcgggcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaagggcatgagctacttggaggacgtgcgg
cttgtgcacagggacctggctgcccgcaacgtgctggtcaagagtcccaaccatgtcaag
attacggacttcgggctggctcggctgctggacattgacgagacggagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcattggagtccattctccgccggcggttcacc
caccagagtgatgtctggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgcctcagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttggtggccgaattctcccggatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccggccagccccttg
gacagcaccttctaccgctcgctgctggaggatgacgacatgggggacctggtggatgct
gaggagtacctggtaccccagcagggcttcttctgcccagaccctgccccgggcgctggg
ggcacagcccaccgcaggcaccgcagcacatccaccaggagtggcggtggtgagctgacg
ctggggctggaggcctctgaggaggagccccccaagtctccactggcaccttccgaaggg
gccggctctgacgtgttcgacggcgacctgggcatgggggcagccaaggggctgcagaac
ctcccccaacacgactctagccctctacagcggtacagtgaggaccccacagtacccctg
cctcctgaaactgatggctacgttgcccccctgacctgcagcccccagcccgaatacgtg
aaccagccggaggttcggccacagcccccctcgcccctagagggtcctctgcctcctcct
cgacctactggagccaccctggaaaggcccaagacgctctcccctggaaggaacggggtt
gtcaaggacgtttttgcctttggtgctgcagtggagaatccagagtacttggcaccccgg
ggcagggctccctctcagaaccacccttctccggccttcagcccagcctttgacaacctc
tattactgggaccaggacccatcagaccggggcgctctacccagcacctttgaagggacc
ccgactgcagagaaccccgaatacctgggtctggatgtgccagtatga
DBGET
integrated database retrieval system
