Sus scrofa (pig): 396665
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Entry
396665 CDS
T01009
Gene name
TGFBR1
Definition
(RefSeq) TGF-beta receptor type-1 precursor
KO
K04674
TGF-beta receptor type-1 [EC:
2.7.11.30
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc04010
MAPK signaling pathway
ssc04060
Cytokine-cytokine receptor interaction
ssc04068
FoxO signaling pathway
ssc04144
Endocytosis
ssc04218
Cellular senescence
ssc04350
TGF-beta signaling pathway
ssc04371
Apelin signaling pathway
ssc04380
Osteoclast differentiation
ssc04390
Hippo signaling pathway
ssc04520
Adherens junction
ssc04659
Th17 cell differentiation
ssc04926
Relaxin signaling pathway
ssc04933
AGE-RAGE signaling pathway in diabetic complications
ssc05142
Chagas disease
ssc05161
Hepatitis B
ssc05166
Human T-cell leukemia virus 1 infection
ssc05200
Pathways in cancer
ssc05210
Colorectal cancer
ssc05212
Pancreatic cancer
ssc05220
Chronic myeloid leukemia
ssc05225
Hepatocellular carcinoma
ssc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
396665 (TGFBR1)
04350 TGF-beta signaling pathway
396665 (TGFBR1)
04390 Hippo signaling pathway
396665 (TGFBR1)
04371 Apelin signaling pathway
396665 (TGFBR1)
04068 FoxO signaling pathway
396665 (TGFBR1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
396665 (TGFBR1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
396665 (TGFBR1)
09143 Cell growth and death
04218 Cellular senescence
396665 (TGFBR1)
09144 Cellular community - eukaryotes
04520 Adherens junction
396665 (TGFBR1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
396665 (TGFBR1)
09152 Endocrine system
04926 Relaxin signaling pathway
396665 (TGFBR1)
09158 Development and regeneration
04380 Osteoclast differentiation
396665 (TGFBR1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
396665 (TGFBR1)
09162 Cancer: specific types
05210 Colorectal cancer
396665 (TGFBR1)
05212 Pancreatic cancer
396665 (TGFBR1)
05225 Hepatocellular carcinoma
396665 (TGFBR1)
05226 Gastric cancer
396665 (TGFBR1)
05220 Chronic myeloid leukemia
396665 (TGFBR1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
396665 (TGFBR1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
396665 (TGFBR1)
05161 Hepatitis B
396665 (TGFBR1)
09174 Infectious disease: parasitic
05142 Chagas disease
396665 (TGFBR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
396665 (TGFBR1)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
396665 (TGFBR1)
Protein kinases [BR:
ssc01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
396665 (TGFBR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Activin_recp
Pkinase_fungal
APH
FTA2
Motif
Other DBs
NCBI-GeneID:
396665
NCBI-ProteinID:
NP_001033728
Ensembl:
ENSSSCG00000005382
ENSSSCG00000023995
Vega:
OTTSUSG00000002966
UniProt:
Q5CD18
LinkDB
All DBs
Position
1
AA seq
503 aa
AA seq
DB search
MEVAAGAPRSRLLLFVLAATATLAPEATAFQCFCHLCTKDNFTCVTDGLCFVSVTETTDK
VIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGPFPGKPPSG
LGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
atggaggtggcggccggtgctccgcgttcccggctgctcctcttcgtgctggcggcgacg
gccacgctggccccggaggcgacggcattccagtgtttctgccacctttgcacaaaagac
aattttacttgtgtcacagatgggctctgctttgtctccgtcacagagaccacagacaaa
gttatacacaatagcatgtgtatagctgaaattgacctaattccgcgagacaggccattt
gtatgtgcaccttcttcaaaaactgggtctgttactacaacatattgctgcaatcaggac
cattgcaataaaatagaactcccaactgttggtccttttccaggaaagccaccatctggc
cttggtcctgttgaactggcagctgtcattgctggaccagtctgctttgtctgcatctca
ctcatgttgatggtctatatctgccataaccgtacagtcattcaccatcgagtgccaaat
gaagaggatccttcattagatcgcccttttatttcagagggtactacattaaaagattta
atttatgatatgacaacatcaggttctggatcaggcttaccattgcttgttcagagaaca
attgcaagaactattgtgctacaagaaagtattggcaaaggtcgatttggagaggtttgg
cgaggaaaatggagaggagaggaagttgctgttaaaatattctcctccagggaagaacgt
tcatggttccgtgaggcagagatttatcagactgttatgttacgtcatgaaaacatcttg
ggatttatagcagcagacaataaagataatggtacatggactcagctttggttggtgtca
gattatcatgaacatggatccctttttgattacttgaatagatacacagttactgtggaa
ggaatgataaaacttgctctgtccacagcaagtggacttgcccatcttcacatggagata
gttggtacccaaggaaaaccagctattgctcatagagatttgaaatcaaagaatatcttg
gtaaaaaagaatggaacttgctgtattgcagacttaggactggcagtaagacatgattca
gccacagatacaattgatattgctccaaaccacagagtgggaacaaaaaggtacatggcc
cctgaagttctagatgattccataaatatgaaacactttgaatccttcaaacgtgctgac
atctatgcaatgggcttagtattctgggaaatagctcgacgatgttccattggtggaatt
catgaagattaccagctgccttattatgatcttgtaccttctgatccatcagttgaagaa
atgagaaaagttgtttgtgaacagaagttaaggccaaatattcctaacagatggcagagc
tgtgaagccttaagagtaatggctaaaattatgagagaatgttggtatgccaatggagca
gccaggctcacagctttgcggattaagaaaacattgtcacaactcagtcagcaggaaggc
atcaaaatgtaa
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