Sus scrofa (pig): 397070
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Entry
397070 CDS
T01009
Gene name
EGFR
Definition
(RefSeq) epidermal growth factor receptor precursor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
ssc
Sus scrofa (pig)
Pathway
ssc01521
EGFR tyrosine kinase inhibitor resistance
ssc01522
Endocrine resistance
ssc04010
MAPK signaling pathway
ssc04012
ErbB signaling pathway
ssc04014
Ras signaling pathway
ssc04015
Rap1 signaling pathway
ssc04020
Calcium signaling pathway
ssc04066
HIF-1 signaling pathway
ssc04068
FoxO signaling pathway
ssc04072
Phospholipase D signaling pathway
ssc04144
Endocytosis
ssc04151
PI3K-Akt signaling pathway
ssc04510
Focal adhesion
ssc04520
Adherens junction
ssc04540
Gap junction
ssc04630
JAK-STAT signaling pathway
ssc04810
Regulation of actin cytoskeleton
ssc04912
GnRH signaling pathway
ssc04915
Estrogen signaling pathway
ssc04921
Oxytocin signaling pathway
ssc04926
Relaxin signaling pathway
ssc04928
Parathyroid hormone synthesis, secretion and action
ssc04934
Cushing syndrome
ssc05160
Hepatitis C
ssc05163
Human cytomegalovirus infection
ssc05165
Human papillomavirus infection
ssc05171
Coronavirus disease - COVID-19
ssc05200
Pathways in cancer
ssc05205
Proteoglycans in cancer
ssc05206
MicroRNAs in cancer
ssc05210
Colorectal cancer
ssc05212
Pancreatic cancer
ssc05213
Endometrial cancer
ssc05214
Glioma
ssc05215
Prostate cancer
ssc05218
Melanoma
ssc05219
Bladder cancer
ssc05223
Non-small cell lung cancer
ssc05224
Breast cancer
ssc05225
Hepatocellular carcinoma
ssc05226
Gastric cancer
ssc05230
Central carbon metabolism in cancer
ssc05231
Choline metabolism in cancer
ssc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ssc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
397070 (EGFR)
04012 ErbB signaling pathway
397070 (EGFR)
04014 Ras signaling pathway
397070 (EGFR)
04015 Rap1 signaling pathway
397070 (EGFR)
04630 JAK-STAT signaling pathway
397070 (EGFR)
04066 HIF-1 signaling pathway
397070 (EGFR)
04068 FoxO signaling pathway
397070 (EGFR)
04020 Calcium signaling pathway
397070 (EGFR)
04072 Phospholipase D signaling pathway
397070 (EGFR)
04151 PI3K-Akt signaling pathway
397070 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
397070 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
397070 (EGFR)
04520 Adherens junction
397070 (EGFR)
04540 Gap junction
397070 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
397070 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
397070 (EGFR)
04915 Estrogen signaling pathway
397070 (EGFR)
04921 Oxytocin signaling pathway
397070 (EGFR)
04926 Relaxin signaling pathway
397070 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
397070 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
397070 (EGFR)
05206 MicroRNAs in cancer
397070 (EGFR)
05205 Proteoglycans in cancer
397070 (EGFR)
05230 Central carbon metabolism in cancer
397070 (EGFR)
05231 Choline metabolism in cancer
397070 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
397070 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
397070 (EGFR)
05212 Pancreatic cancer
397070 (EGFR)
05225 Hepatocellular carcinoma
397070 (EGFR)
05226 Gastric cancer
397070 (EGFR)
05214 Glioma
397070 (EGFR)
05218 Melanoma
397070 (EGFR)
05219 Bladder cancer
397070 (EGFR)
05215 Prostate cancer
397070 (EGFR)
05213 Endometrial cancer
397070 (EGFR)
05224 Breast cancer
397070 (EGFR)
05223 Non-small cell lung cancer
397070 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
397070 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
397070 (EGFR)
05171 Coronavirus disease - COVID-19
397070 (EGFR)
05163 Human cytomegalovirus infection
397070 (EGFR)
05165 Human papillomavirus infection
397070 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
397070 (EGFR)
01522 Endocrine resistance
397070 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssc01001
]
397070 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ssc04147
]
397070 (EGFR)
Enzymes [BR:
ssc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
397070 (EGFR)
Protein kinases [BR:
ssc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
397070 (EGFR)
Exosome [BR:
ssc04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
397070 (EGFR)
Exosomal proteins of pancreatic cancer cells
397070 (EGFR)
Exosomal proteins of bladder cancer cells
397070 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
Kinase-like
APH
Borrelia_P83
Kdo
Motif
Other DBs
NCBI-GeneID:
397070
NCBI-ProteinID:
NP_999172
Ensembl:
ENSSSCG00000022126
ENSSSCG00000023985
UniProt:
Q8MIL8
LinkDB
All DBs
Position
9
AA seq
1209 aa
AA seq
DB search
MRRSWAGGAALLALLAAHFQASPALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYMQNSYNLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNVLYENTHALA
VLSNYGANKTGLRELPMRNLQEILQGAVRFSNNPALCHAESIQWRDIVNSDFLSNMSMDF
QSQLGSCPKCDPGCLNGSCWGAGKENCQKLTKVICAQQCSGRCRGRSPSDCCHNQCAAGC
TGPRESDCLVCRRFRDEATCKDTCPPLMLYNPTTYQMDVNPLGKYSFGATCVKKCPRNYV
VTDHGSCVRACSSDSYEVEEDGVRKCKKCDGPCGKVCNGIGIGEFKDTLSINATNIKHFR
NCTSISGDLHILPVAFRGDSFTRTPPLDPKELDILKTVKEITGFLLIQAWPENRTGLHAF
ENLEIIRGRTKQHGQFSLAVVGLDIASLGLRSLKEISDGDVIVSGNRNLCYANTISWKKL
FGTASQKTKIINNRSEKECKAMGHICNPLCSSEGCWGPEPRDCMSCRNFSRGKECVEKCN
VLEGEPREFVENAECVQCHPECLPQAKNVTCMGRGPDSCVRCAHYIDGPHCVKTCPAGIA
GENSTLIWKFADANHVCHLCHPNCTYGCVGPGLEGCAVDRPKIPSIATGIVGGLLLAVVL
ALGVGLFLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKVKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQHLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWLALESILHRVYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISTVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLVPQ
QGFFHSPATSRTPLLSSLSATSSTPAVACVDRNGQSYPLKEDSFLQRYSSDPTGALTEDS
LDDTFLPAPEYVNQSVPKRPAGSVQNPVYHNQPLSAAPGRDPHYQNSHSNAVGNPEYLNT
PRPACINGGLDGPAFWAQTGSHQINLDNPDYQQAFFPKEAKSNGICKGPAAENAEYLRAA
PASSDLTGA
NT seq
3630 nt
NT seq
+upstream
nt +downstream
nt
atgcgacgctcctgggcgggcggcgccgcgctcctggcgctgctggccgcgcacttccag
gcgagtccggcgctggaggagaagaaagtttgccaaggtacaagtaacaagctcacccag
ctgggcactttcgaagaccactttctgagcctccagaggatgttcaataactgcgaggtg
gtccttgggaacttggagatcacctacatgcagaacagctacaacctgtctttcctaaag
accattcaggaggtcgccggctacgtgctcatcgccctcaacaccgtggagaagatccct
ttggaaaacctgcagatcatccgaggaaatgtactgtatgaaaacacccatgccttagcc
gtcttatccaactacggggccaataaaaccggcctgagggagctgcccatgaggaactta
caagagatcctgcaaggcgccgtgcgcttcagcaacaaccctgccctctgtcacgcggag
tccatccagtggagggacattgtcaacagcgactttctaagcaacatgtccatggacttt
cagagccagctgggcagctgcccgaagtgtgatccaggctgtctcaatgggagctgctgg
ggtgctgggaaggagaactgccagaaattgaccaaagtcatctgtgcccagcagtgctcc
gggcgctgccgcggccggtcgcccagtgactgctgccacaaccagtgcgccgctggctgc
acggggccgcgggagagcgactgcctggtttgccgcagattccgtgacgaggccacctgc
aaggacacatgcccgccgctcatgctctacaaccccaccacctaccagatggacgtcaac
ccgctggggaagtacagctttggcgccacctgtgtcaagaagtgccctcgtaactacgtg
gtgacagaccatggctcctgtgtccgtgcctgcagctccgacagctacgaggtggaggag
gacggcgtccgcaagtgtaaaaagtgtgacgggccctgcggcaaagtttgtaacgggata
gggattggcgagtttaaagacacactttccataaatgctacgaatatcaagcacttcagg
aactgcacctcgatcagcggagatcttcatatcctgccggtagcatttaggggtgactcc
ttcacacgcacgccgcctctggaccccaaggaactggacatcctgaaaaccgtgaaggaa
ataacagggtttttactgattcaggcctggcctgaaaacaggactggcctccatgctttt
gagaacctggaaatcatacgtggcaggacgaagcaacatggtcagttttccctcgcggtt
gttggcctggacatagcgtccttggggytgcgctccctcaaggagatcagcgacggagac
gtgatcgtctcaggaaaccgaaacctgtgctatgcaaatacaatcagctggaaaaaacta
tttgggaccgcaagtcagaaaaccaaaattataaacaacaggagcgaaaaagagtgcaaa
gccatgggccacatctgtaacccgctgtgctcatcagagggctgctggggccctgaaccc
agagactgcatgtcctgtcgaaactttagccgcggcaaggaatgtgtggagaagtgcaac
gttctggagggggagccgagagagttcgtggagaatgccgagtgtgtgcagtgccacccg
gagtgcctgccccaggccaagaacgtgacctgcatgggacgcggaccggacagctgtgtc
cggtgtgctcactacatcgacggccctcactgtgtcaagacctgccccgcgggaatcgca
ggagaaaacagcaccctcatctggaagtttgcggatgccaaccacgtgtgtcacctgtgc
caccccaactgcacctacggctgtgtcggaccaggtctcgagggctgtgcggtggacagg
cccaagatcccgtccatcgccaccgggatagtggggggcctgcttctggccgtggtgctg
gccctgggggtcggcctctttctgcgcaggcgccacatcgtccgcaagcgcacgctgcgc
cggctgctgcaggagcgggagctggttgagcctctcacacccagtggagaagctcccaac
caagctctcttgaggatcctgaaggagacggaattcaaaaaggtcaaggtgctgggctcc
ggcgcgttcggcacggtgtacaagggcctctggatcccagaaggtgagaaggtgaaaatt
cctgtggctatcaaggaattaagagaagccacttctccaaaagccaacaaggaaattctt
gacgaagcctacgtgatggccagtgtggacaatcctcatgtgtgccgcctcctgggcatc
tgcctgacctccacggtgcagctcatcacgcagctcatgcccttcggctgcctcctggac
tacgtccgcgagcacaaggacaacatcggctcccagcacctgctcaactggtgtgtgcag
atcgcaaagggcatgaactatctggaagaccggcgcttggtgcaccgagacctggcggcc
aggaatgtgctggtgaagacaccgcagcatgtcaagatcactgactttgggctggccaag
ctgctgggcgccgaggagaaagagtaccacgcggaaggaggcaaagtgcccatcaagtgg
ctggctctagagtcaatcctgcaccgtgtatacacccaccagagtgacgtctggagctac
ggagtcaccgtttgggagctgatgacctttgggtccaagccttatgacgggatccccgcg
agtgagatctcgaccgtcctggagaagggagagcgcctcccgcagccccccatctgcacc
attgatgtctacatgatcatggtcaagtgctggatgatagatgctgatagtcgcccaaag
ttccgtgagctgatcatcgaattctccaaaatggcccgagacccccagcgctaccttgtc
atccagggagacgagcgaatgcacttgccaagccctacggactccaacttctaccgcgcc
ctgatggacgaggaggacatggaggatgtggtggacgccgacgagtacctcgtcccccag
cagggcttcttccacagccccgccacctcccggacgccgctgctcagctctctgagcgcc
accagcagcacccccgctgtggcttgcgttgacagaaacgggcagagttatcccctcaag
gaagacagcttcctgcagcggtacagctccgaccccactggcgccctgaccgaggacagc
ctagacgacacttttctcccagcacccgaatatgtaaaccagtctgttcccaagaggccc
gcgggctccgtccagaaccctgtctaccacaatcagcctctcagtgcagctcctggccgg
gacccccactaccagaactcccacagcaatgccgtgggcaaccctgagtatctcaacacc
ccccgccccgcctgcatcaacggaggactggacggccctgccttctgggcacagacaggc
agccaccagattaatctggacaacccagactaccagcaggccttcttccccaaggaagcc
aagtcaaacggcatctgtaagggtcccgccgccgaaaacgcagagtacctaagggcggca
ccagccagcagtgaccttactggggcatga
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integrated database retrieval system
