KEGG   Sus scrofa (pig): 397117Help
Entry
397117            CDS       T01009                                 

Gene name
GSTO1
Definition
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00480  Glutathione metabolism
ssc00980  Metabolism of xenobiotics by cytochrome P450
ssc00982  Drug metabolism - cytochrome P450
ssc00983  Drug metabolism - other enzymes
ssc01524  Platinum drug resistance
ssc05200  Pathways in cancer
ssc05204  Chemical carcinogenesis
ssc05225  Hepatocellular carcinoma
ssc05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    397117 (GSTO1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    397117 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    397117 (GSTO1)
   00983 Drug metabolism - other enzymes
    397117 (GSTO1)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    397117 (GSTO1)
   05204 Chemical carcinogenesis
    397117 (GSTO1)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    397117 (GSTO1)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    397117 (GSTO1)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    397117 (GSTO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ssc02000]
    397117 (GSTO1)
Enzymes [BR:ssc01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     397117 (GSTO1)
Transporters [BR:ssc02000]
 Other Transporters
  Pores ion channels [TC:1]
   397117 (GSTO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 397117
NCBI-ProteinID: NP_999215
Ensembl: ENSSSCG00000022351
UniProt: Q9N1F5
LinkDB All DBs
Position
14
AA seq 241 aa AA seqDB search
MSGGSARSLGKGSAPPGPVPEGLIRVYSMRFCPFAQRTLLVLNAKGIRHQVININLKNKP
EWFFQKNPSGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMVFELS
SKVPPLLIRFIRRENEADCSGLKEELRKEFSKLEEVLTKKKTTYFGGSSLSMIDYLIWPW
FERLEALELNECIDHTPKLKLWMAAMMKDPAVSALHIEPRDLRAFNDLYLQNSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtctggaggatcagccagaagcctggggaagggaagtgcgcccccggggccggtcccc
gagggcctgatccgtgtctacagcatgagattctgtcctttcgcccagaggactctcctg
gtcctgaatgccaagggaatccggcatcaagtcatcaacatcaacctgaaaaataagcct
gagtggttcttccagaagaatccctcaggtctggtgccagttctggaaaacagtcagggt
caactgatctatgaatctgccatcacttgtgagtacctggatgaagcatatccagggaag
aagctgttgccagatgacccctatgagaaagcttgccaaaagatggtctttgagttgtct
tctaaggtaccgcctttgctaatacgctttattagaagggaaaatgaggcagactgctct
ggcctaaaagaagaattacgtaaagaattcagcaagctagaggaggttctgaccaaaaag
aagacaacatactttggtggaagttctctttctatgattgattacctcatctggccctgg
tttgaaaggctggaagccctggagttaaatgagtgtatagaccacactccaaaacttaag
ctctggatggcagccatgatgaaagatccggcggtatcagccctccacattgaaccgaga
gaccttcgagctttcaatgacctctacttgcagaacagcccagaggcctgtgactatggg
ctctga

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