KEGG   Spirochaeta thermophila DSM 6578: Spith_1828Help
Entry
Spith_1828        CDS       T02016                                 

Definition
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
stq  Spirochaeta thermophila DSM 6578
Pathway
stq00473  D-Alanine metabolism
stq00550  Peptidoglycan biosynthesis
stq01100  Metabolic pathways
stq01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:stq00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00473 D-Alanine metabolism
    Spith_1828
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Spith_1828
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Spith_1828
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:stq01011]
    Spith_1828
Enzymes [BR:stq01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Spith_1828
Peptidoglycan biosynthesis and degradation proteins [BR:stq01011]
 Precursor biosynthesis
  Amino acid ligase
   Spith_1828
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4 ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID: AEJ62087
UniProt: G0GCM1
LinkDB All DBs
Position
2046918..2048012
Genome map
AA seq 364 aa AA seqDB search
MRGMERMRIALLYGGRSGEHEVSCRSAAAIYEHLDRERFEVLPVGITHEGRWYLQREVRV
KDGALEVTEDEGAVVWAVPGAGLWCGGEDLRVDCVFPIVHGTFGEDGTLQGLLEQAGVAY
VGAGVLGSALGMDKDRAKAVWLQAGLPILPFMVVRRESLPPWNELAIQLRRRMEFPVFVK
PARGGSSVGISKVHDERGLKKACELAFTYDSKIVIEQGIEAREIECGVWGNEDVRSFPPG
EIIHTHEFYDYEAKYEDTEGLQLKIPAELTPEQQEYVRNVAEKAYRALECEGFARVDFLL
DTETEVFYLNEINTLPGFTPVSMFPLMAQAAGISFPDLLTRLIELGLDRSRRRAALSYRY
EALR
NT seq 1095 nt NT seq  +upstreamnt  +downstreamnt
atgcggggcatggaacggatgaggatcgccttgctctacggtggacgctcaggggaacac
gaggtctcgtgcaggtcggcggccgcgatctacgagcacctcgatcgcgagaggttcgag
gtcctgccggtagggatcacccacgagggacggtggtacctgcagcgcgaggtgcgggtg
aaggacggggcgctggaggtgacagaggacgagggggcggtggtgtgggcggtgccgggc
gcggggctctggtgcgggggggaagacctgagggtggactgcgtcttccccatcgtgcac
ggcaccttcggagaggacggcacgctccagggactgctggagcaggccggggtggcgtac
gtgggggcgggggtgctcgggagcgcgttggggatggacaaggacagggccaaggcggtg
tggctgcaggcggggctccccatccttcccttcatggtggtacgccgggagtcactccct
ccctggaacgagcttgcgattcagctcagacggagaatggagtttcccgtctttgtgaag
cccgcccggggcggttcctctgtgggcatctcaaaggtccacgacgagcgggggctcaag
aaggcctgtgaactcgccttcacgtacgactcgaagatcgtcatcgagcaggggatcgag
gcccgggagatcgaatgcggggtgtggggaaacgaggacgtacggagcttccctcccggc
gagatcatccacacgcacgaattctacgattacgaggccaagtacgaggacaccgaaggt
cttcagctcaagatccctgcagagctcacccctgaacagcaggagtacgtacggaacgtg
gcggagaaggcctacagggccctcgagtgtgagggattcgcgcgagtcgattttctcctc
gacaccgagaccgaggtcttctacctcaacgagatcaacacccttccgggattcacgccg
gtgagcatgttccccctcatggcccaggcagcgggcatctcgtttcccgacctcctcacc
aggctcatcgaactggggctcgatcgcagcaggaggagagccgccctctcataccgctac
gaggccctccgctga

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