KEGG   Streptococcus pyogenes Alab49 (serotype M53): SPYALAB49_001156Help
Entry
SPYALAB49_001156  CDS       T02019                                 

Gene name
ddl
Definition
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
stz  Streptococcus pyogenes Alab49 (serotype M53)
Pathway
stz00473  D-Alanine metabolism
stz00550  Peptidoglycan biosynthesis
stz01100  Metabolic pathways
stz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:stz00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00473 D-Alanine metabolism
    SPYALAB49_001156 (ddl)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SPYALAB49_001156 (ddl)
 09160 Human Diseases
  09168 Drug resistance
   01502 Vancomycin resistance
    SPYALAB49_001156 (ddl)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:stz01011]
    SPYALAB49_001156 (ddl)
Enzymes [BR:stz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     SPYALAB49_001156 (ddl)
Peptidoglycan biosynthesis and degradation proteins [BR:stz01011]
 Precursor biosynthesis
  Amino acid ligase
   SPYALAB49_001156 (ddl)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 Cohesin
Motif
Other DBs
NCBI-ProteinID: AEQ24753
LinkDB All DBs
Position
complement(1122261..1123307)
Genome map
AA seq 348 aa AA seqDB search
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIRTQQFSEKPS
ESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVM
SSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSV
GISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDF
YDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEIFDQRESHLI
NT seq 1047 nt NT seq  +upstreamnt  +downstreamnt
atgtccaaacaaacgttagttctattatacggaggccgctcagcagaacgtgaagtctca
gtgctttcagcagagagtgtgatgcgagcagtcaactatgataagttcttagtaaaaact
tattttattactcagatgggccaatttatcagaactcagcaattttcagaaaagccatcg
gaatcagaacgcttgatgacaaatgagacgatagagctaactcaaaaaataaaaccaagt
gatatctatgaagaaggtgcagttgtatttcctgtattacatggacctatgggagaagat
ggctctatccaaggtttcttagaagtgcttagaatgccatatatagggactaatgtcatg
tcttctagcatagctatggataaaattactactaaacgtgtcttagaatcaattggaatt
ccacaagttgcctatactgtttatattgacggacaagatttggaggcttgtttagttgaa
actttagcaagacttacttttcctatcttcgtaaaaccagctaatatgggttcttccgtg
gggatttccaaagcccaaacaaaagtagagttaagaaaagcgattcagttagccctgacc
tatgacagtcgtgttttgattgaacaaggcgtagttgccagagaaattgaagttggtctc
cttggaaatgataaggttaaatcaactctaccaggagaagtaatcaaggacgttgatttt
tacgactaccaagcaaaatatgttgataataagattacgatggccattccagcagatgta
gatcagagtattgtgacagaaatgcgttcttatgctgaagtagcctttaaagccttaggt
ggttgcgggttgtcccgttgtgactttttcttgacccaagacggacaggtttaccttaac
gaattaaacaccatgccaggctttacccaatggtctatgtatccactcttatgggaaaat
atgggattggcttatccagatttgattgaagagctggtgacactggcacaagaaatattt
gatcagcgtgagagccatctgatttaa

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