KEGG   Thermobispora bispora: Tbis_3582
Entry
Tbis_3582         CDS       T01236                                 
Name
(GenBank) D-alanine/D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tbi  Thermobispora bispora
Pathway
tbi00470  D-Amino acid metabolism
tbi00550  Peptidoglycan biosynthesis
tbi01100  Metabolic pathways
tbi01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tbi00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Tbis_3582
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Tbis_3582
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Tbis_3582
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tbi01011]
    Tbis_3582
Enzymes [BR:tbi01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Tbis_3582
Peptidoglycan biosynthesis and degradation proteins [BR:tbi01011]
 Precursor biosynthesis
  Amino acid ligase
   Tbis_3582
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp_3 ATP-grasp TTL ATP-grasp_4 ATPgrasp_ST RimK ATPgrasp_YheCD GARS_A
Other DBs
NCBI-ProteinID: ADG90270
UniProt: D6YAL7
LinkDB
Position
4177708..4178658
AA seq 316 aa
MSDLSHVLVLAGGLSYEREVSLRSGRRVAEVLRAAGVDVEVRDTDAGLVPAVLADPPEAA
FVALHGGVGEDGAIRSVLELLNVPYVGATPDACRVAFDKPTAKAVVRSWGLATPDSVALP
KETFHDLGASAVLERIVDRLGLPLFVKPAQGGSALGASIVRTAEELPAAMVGCFAYGDTA
LIEKYIDGVEVSVSVIDLGDGPVALTPVEIVPDGGVYDYAARYTAGRTEFFAPARLTDEE
IEACKAMAVTAHTALGLRDLSRTDIIVDRSGQPYFLEVNVSPGMTETSLFPMAVETAGRD
LGTVFRVLLERAAQRG
NT seq 951 nt   +upstreamnt  +downstreamnt
atgagcgatctcagtcacgtgctcgtcctcgccggagggctctcctacgaacgcgaggtc
tcgctccgctcggggcgccgggtggccgaggtactgcgggccgccggggtggacgtcgag
gtccgggacaccgacgccggcctcgtccccgcggtcctcgccgacccgccggaagcggcg
ttcgtcgccctgcacggcggagtgggcgaggacggcgcgatccggtcggtgctggagctc
ctcaacgtgccgtacgtgggggcgaccccggacgcctgccgcgtcgcgttcgacaagccg
accgccaaggcggtggtccgctcctggggtctcgccacccccgactcggtcgccctgccc
aaggagaccttccacgacctcggcgcgagcgcggtgctcgagcgcatcgtggaccggctc
ggcctgcccctgttcgtgaagccggcccagggcgggtccgcactcggcgcgtccatcgtc
cgcaccgcagaggagctcccggccgcgatggtcggctgcttcgcgtacggtgacaccgcg
ctgatcgagaagtacatcgacggggtggaggtctcggtctccgtcatcgacctcggggac
gggccggtcgccctcaccccggtcgagatcgtgccggacggcggcgtctacgactacgcg
gcccggtacacggccggccggaccgagttcttcgcaccggcccggctcaccgatgaggag
atcgaggcgtgcaaggcgatggccgtcaccgcgcacaccgcgctcggcctgcgcgatctc
tcgcgcaccgacatcatcgtggaccggtcgggccagccgtacttcctcgaggtgaacgtc
tccccggggatgaccgagacctcgctcttccccatggcggtcgagacggccggccgggat
ctgggcacggtgttccgggtgttgctcgagcgcgccgcccagcgcggctga

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