Thermomonas brevis: H9L17_02610
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Entry
H9L17_02610 CDS
T06816
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
tbv
Thermomonas brevis
Pathway
tbv00260
Glycine, serine and threonine metabolism
tbv00261
Monobactam biosynthesis
tbv00270
Cysteine and methionine metabolism
tbv00300
Lysine biosynthesis
tbv01100
Metabolic pathways
tbv01110
Biosynthesis of secondary metabolites
tbv01120
Microbial metabolism in diverse environments
tbv01230
Biosynthesis of amino acids
Module
tbv_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
tbv_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
tbv00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
H9L17_02610 (thrA)
00270 Cysteine and methionine metabolism
H9L17_02610 (thrA)
00300 Lysine biosynthesis
H9L17_02610 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
H9L17_02610 (thrA)
Enzymes [BR:
tbv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
H9L17_02610 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
H9L17_02610 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_7
NAD_binding_3
ACT
Motif
Other DBs
NCBI-ProteinID:
QNN47077
UniProt:
A0A7G9QUQ2
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All DBs
Position
568516..571002
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AA seq
828 aa
AA seq
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MDSSQSAPPKLLRRAHKFGGSSLADAGRIRHVAGLLLADDASNQIAVSSAMHGTTNALVA
LGDAATAGGEWKDALETLCQRHRETARALLEQPDALLAKIDALCGELADLLQATSLLRQP
GRTALERIHGMGEVLSTSLLHAHLVERGGDYALLDAREVLVVRHTDLGAVVDWEQSARNL
ADWRARHPQSRANVTGFVARDERGLPTTLGRNGSDYSAAIFASLFEADELHIWSDVDGVL
SADPRLVPEAVPLAAMSYREACELAYFGAKVIHPQTMTPAIARGLPILMRNTFRPEFPGT
RIDADGDRAAAGPVKGLTLGGHLALVCLEGAGLIGVPGTAERVFAALHAAHISVVMISQG
SSEHSICCVVHEREAAAARDALRDAFARELAGAQVQGVTMQAGISVLAAVGDGMAGTPGV
AARMFDALARARVNIRAIAQGASERNISVAIDSADAARALRAVHAAFWLSPQTIALAVIG
PGKVGSALLDQLQAALPRLRSQHNIDLRLRALATRNQLWLCEHGGDADWRARMQGTPSEA
SLDTLATHLLDTHLPHAVVIDCSASDSVAQRYSEWLAAGIHVITPNKQAGAGPLERFEAI
RAARAKSGARFRYEATVGAGLPVISTLRDLLDTGDELLAIEGIFSGTLAWLFNKFDGEKP
FSELVREAHALGYTEPDPRDDLSGTDVARKLVILARESGMPLSLGNVAVESLVPETLRGA
DRDTFMAGLELLDAPMLARLEAARAKGCALRYVARLERDGKASVALRELPADHAFAHLRL
TDNCVSFTTRRYCDNPLVVQGPGAGPEVTAAGVFSDLLRLAAALGAKL
NT seq
2487 nt
NT seq
+upstream
nt +downstream
nt
atggattcgtcgcagtccgcaccacccaagcttcttcgccgcgcgcacaagttcggcggc
agctcgctggccgacgccggacgcatccgccacgtcgccggcctgctgctggccgacgat
gcgtcgaaccagatcgcggtgtcctccgcgatgcacggcaccaccaatgcgctggtcgcg
ctgggcgatgccgcgaccgccggcggcgaatggaaggacgcgctggaaaccctgtgccag
cgccatcgggaaacggcgcgcgcactgctggagcagcccgacgcgctgctggcgaagatc
gatgcgctctgcggcgaactggccgacctgctgcaagccacgtcgctgttgcgccagccg
gggcgcaccgcgctggaacgcatccacggcatgggcgaggtgctttcgacctcgctgctg
catgcgcacctggtcgaacgcggcggcgactacgccctgctcgacgcgcgcgaagtgctg
gtcgtgcgccataccgatctcggcgcggtggtcgactgggagcaaagcgcgcgcaacctc
gccgactggcgcgcgcgccatccgcagtcgcgcgccaacgtcaccggcttcgtcgcccgc
gacgagcgcggcctgccgaccacgctgggccgcaacggcagcgactactccgccgcgatc
ttcgccagcctgttcgaggccgacgaactgcatatctggagcgacgtcgatggcgtactc
tccgccgacccgcggctggtgccggaagcggtgccgctggccgcgatgagctaccgcgaa
gcctgcgagctagcctatttcggcgccaaggtgatccatccgcagacgatgacgcccgcg
atcgcgcgcggcctgccgatcctgatgcgcaacaccttccgtcccgagttccccggcacc
cgcatcgatgccgacggcgaccgcgccgccgccggcccggtgaaggggctgacgctgggc
ggccacctcgcgctggtgtgcctggaaggcgcgggcctgatcggcgtccccggcaccgcc
gagcgcgtgttcgccgcgttgcacgccgcgcacatctcggtggtgatgatctcgcagggc
tcgtccgaacactcgatctgctgtgtcgtccacgaacgcgaagccgccgccgcgcgcgac
gcgctgcgcgacgccttcgcccgcgagctggccggcgcgcaggtgcagggcgtgaccatg
caggccggcatcagcgtgctggccgcggtaggcgacggcatggccggcacgccgggcgtg
gccgcacggatgttcgacgcgctggcccgcgcccgcgtcaacatccgcgcgatcgcacag
ggcgcgtcggagcgcaacatttcggtggcgatcgattccgccgatgccgcgcgtgcgctg
cgcgccgtgcacgccgcgttctggctgtcgccgcagacgatcgcgttggcggtgatcggc
cccggcaaggtcggcagcgccctgctcgaccagttgcaggccgcgctgccgcgcctgcgc
tctcagcacaacatcgacctgcgcctgcgcgcgctggcgacccgcaaccagctgtggctg
tgcgaacacggcggcgacgccgactggcgcgcgcgcatgcagggcacgccgtccgaggcc
agcctcgacacgctggccacgcacctgctggacacgcatcttccccacgccgtcgtcatc
gattgcagcgccagcgacagcgtggcgcagcgctactcggagtggctggccgccggcatc
cacgtcatcacgccgaacaagcaggccggcgcggggccgctggaacgcttcgaggccatc
cgcgcggcgcgggcgaaaagcggcgcgcgcttccgctacgaggccacggtgggcgcgggc
ctgccggtgatttccaccctgcgcgatctgctggacaccggcgacgaactgctcgccatc
gaaggcatcttctccggcacgctggcctggctgttcaacaagttcgacggcgaaaaaccc
ttttccgaattggtgcgtgaggcgcacgcactgggctataccgaacccgacccgcgcgac
gatctctccggcaccgacgtggcgcgcaagctggtgatcctcgcccgcgaatccggcatg
ccgctgtcgctgggcaacgtcgctgtggaaagcctcgtccccgaaaccctgcgcggcgcc
gaccgcgacaccttcatggccgggctggaattgctggatgcgccgatgctggcacgactg
gaagccgcacgtgccaagggctgcgcgcttcgatatgtcgcgcggttggaacgcgatggc
aaagcgtccgttgcgctgcgcgaacttcccgccgaccatgccttcgcccatttgcgactg
acggacaactgcgtgtcgttcaccacccgccgctattgcgacaacccgctggtcgtgcaa
ggccccggcgcgggcccggaagtgaccgccgccggcgtgttctccgatctgctgcggctg
gccgccgcgctgggggcgaagctgtga
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