Thermaerobacter sp. FW80: E1B22_02590
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Entry
E1B22_02590 CDS
T05930
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
thef
Thermaerobacter sp. FW80
Pathway
thef00470
D-Amino acid metabolism
thef00550
Peptidoglycan biosynthesis
thef01100
Metabolic pathways
thef01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thef00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
E1B22_02590
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E1B22_02590
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E1B22_02590
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
thef01011
]
E1B22_02590
Enzymes [BR:
thef01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
E1B22_02590
Peptidoglycan biosynthesis and degradation proteins [BR:
thef01011
]
Precursor biosynthesis
Amino acid ligase
E1B22_02590
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
Motif
Other DBs
NCBI-ProteinID:
QBS36929
UniProt:
A0A4P7GRS0
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Position
complement(631578..632771)
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AA seq
397 aa
AA seq
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MVQHAAGGRRLRVGILFGGRSGEHEVSLMSARSVFRAIDRQRFEPVPIGITRSGQWILPH
DAEALLGAGRGVEPADGDPLAVVPGPGGRRLLVLAAGGAGRWLEPLDVVFPVLHGTYGED
GTVQGLLELLDVPYVGAGVMASAVGMDKAVMKELFRARGLPVVPFVVVTATRWRREPAAV
IEGIEGTLGYPCFTKPANLGSSVAIRKCRDRRQLADGLEEALAYDRKAVVERGVDARELE
ISVLGNDEPMASLPGEIRPRAEFYTYEAKYTEGGAELIVPAPVPPRVVEAMQRLAIAAFQ
AVDAAGMARVDFFLERATGRLLVNEINTIPGFTAYSMYPRLWEAAGLPYRDLITRLIELA
LERHGERARLRTTYGDGGGGDAQGGGDGAGTGSDGQG
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
gtggtgcagcacgcggcgggcgggcggcggttgcgggtggggatcctcttcggcggccgc
tcgggggagcacgaggtctcgctgatgtcggcgcggtcggtgttccgggccatcgaccgc
cagcggttcgaaccggtacccatcggcatcacccgatccgggcagtggatcctgccccac
gacgccgaggcgctgctcggggcgggccgcggggtcgaaccggccgacggcgaccccctg
gcggtggtgcccggccccggcgggcgccgactgctggtgctggcggccggcggcgcgggc
cggtggctggagccgctggacgtggtcttccccgtgctgcacggcacctacggcgaggac
ggcacggtccagggcttgctggagctcctggacgtcccctacgtgggcgcgggggtcatg
gcctcggcggtggggatggacaaggcggtgatgaaggagctcttccgcgcccgcgggttg
ccggtggtgcccttcgtggtggtgacggcgacccgctggcgccgggagccggcggccgtg
atcgaggggatcgagggtaccctcggctacccgtgcttcaccaagcccgccaacctcggg
tccagcgtggcgatccgcaagtgccgggaccgtcggcagctggccgacggcctggaggag
gccctggcctatgaccgcaaggccgtggtggagcgcggcgtggacgcccgggagctggag
atcagcgtcctgggcaacgacgagcccatggcctcgctgcccggcgagatccggccgcgg
gcggagttctacacctacgaggccaagtacaccgagggtggcgccgagttgatcgtgccc
gcgcccgtgccgccgcgggtcgtcgaggcgatgcagcgcctcgccatcgcggcgttccag
gcggtcgacgccgccggcatggcgcgggtcgacttcttcctcgagcgggccaccgggcgg
ctgctggtcaacgagatcaacaccatccccggcttcaccgcctacagcatgtatccccgg
ctctgggaggcggcgggcctgccctatcgcgacctgatcacccggttgatcgagctggcc
ctggaacgccatggtgaacgggcccgcctgcggacaacctatggggacgggggcggtggc
gacgcgcaggggggcggcgacggcgcagggacgggcagcgacgggcagggatag
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