Thermotoga maritima MSB8: THMA_0266
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Entry
THMA_0266 CDS
T03902
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tmw
Thermotoga maritima MSB8
Pathway
tmw00470
D-Amino acid metabolism
tmw00550
Peptidoglycan biosynthesis
tmw01100
Metabolic pathways
tmw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tmw00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
THMA_0266
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
THMA_0266
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
THMA_0266
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tmw01011
]
THMA_0266
Enzymes [BR:
tmw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
THMA_0266
Peptidoglycan biosynthesis and degradation proteins [BR:
tmw01011
]
Precursor biosynthesis
Amino acid ligase
THMA_0266
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_3
ATP-grasp_4
ATP-grasp
CPSase_L_D2
RimK
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AKE28061
UniProt:
P46805
LinkDB
All DBs
Position
268751..269662
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AA seq
303 aa
AA seq
DB search
MRVALLMGGVSREREISLRSGERVKKALEKLGYEHTVFDVREDFLKKVDQLKSFDVVFNV
LHGTFGEDGTLQAILDFLGIRYTGSDAFSSMICFDKLVTYRFLKGTVEIPDFVEIKEFMK
TSPLGYPCVVKPRREGSSIGVFVCESDEEFQHALKEDLPRYGSVIVQKYIPGREMTVSIL
ETEKGFEILPVLELRPKRRFYDYVAKYTKGETEFILPAPLNPSEERLVKEMALKAFVEAG
CRGFGRVDGIFSDGRFYFLEINTVPGLTETSDLPASAKAGGIEFEELVEIILKSAFLKEG
VRV
NT seq
912 nt
NT seq
+upstream
nt +downstream
nt
gtgagagtggctctcctgatgggaggagtgtcgagggaaagggaaatctctctgagaagc
ggagaaagggtaaaaaaggctcttgaaaaactcgggtatgaacacaccgtttttgacgtt
agagaagattttctcaagaaagtggatcagttgaaaagttttgatgtggtcttcaacgtt
ctccatggaactttcggtgaggatggaacgcttcaggcaattctggattttttggggatc
agatacaccgggtccgatgcgttttcaagcatgatatgttttgataaactcgtgacttac
aggtttttaaagggcaccgtcgagatacctgattttgtggagatcaaggaattcatgaaa
acttctccccttgggtatccctgtgtggtaaaaccgaggagagagggttcaagcatagga
gtgttcgtttgtgaatcggatgaagagtttcaacacgcgctcaaggaagatttaccacga
tatgggagtgtgattgttcaaaagtacatccccggcagggaaatgactgtgtctatttta
gaaacggaaaagggcttcgaaattcttcccgttcttgagttgcgaccaaagcgtcgtttc
tacgattacgttgcgaagtacacgaaaggtgaaacggagttcattcttcctgctcctttg
aatccttcagaagaacgccttgtcaaggaaatggctctcaaagcgtttgtagaagctggt
tgcagaggttttgggagggtggatggtattttcagcgatggcaggttctactttctggaa
atcaacacggtaccgggtctaacggaaaccagtgatctcccagcgagcgcgaaagcggga
ggaatcgagttcgaggaactcgttgagatcatcttaaagagcgcttttttgaaagaaggg
gtgagagtatga
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