Thermotoga petrophila RKU-10: Tnap_0332
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Entry
Tnap_0332 CDS
T01139
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tnp
Thermotoga petrophila RKU-10
Pathway
tnp00290
Valine, leucine and isoleucine biosynthesis
tnp00620
Pyruvate metabolism
tnp01100
Metabolic pathways
tnp01110
Biosynthesis of secondary metabolites
tnp01210
2-Oxocarboxylic acid metabolism
tnp01230
Biosynthesis of amino acids
Module
tnp_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tnap_0332
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tnap_0332
Enzymes [BR:
tnp01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tnap_0332
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
SpoIISA_toxin
Motif
Other DBs
NCBI-ProteinID:
ADA66435
UniProt:
D2C649
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Position
333758..335374
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AA seq
538 aa
AA seq
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MSIKVYDTTLRDGAQAFGVSFSLEDKIRIAEALDDLGVHYLEGGWPGSNPKDIAFFEAVK
GMNFKNLKVAAFSSTRRPDVKIEEDANIQTLIKAETPVYTIFGKSWDLHVEKALRTTLEE
NLKMIYDTVSYLKRFADEVIYDAEHFFDGYKANREYALKTLKVAEEAGADCLVLADTNGG
TLPHEIEEIIEDVKKHVKAPLGIHAHNDSDVAVANTLVAVRKGAVHVQGTINGLGERCGN
ANLCSVIPNLVLKMGLEVIPKENLKKLFDVAHLVAELSGRPHIENMPYVGDYAFAHKGGV
HVSAIKRDPRTYEHIDPELVGNRRIISISELSGKSNVLEKIKEMGFEIDESSPKVREILK
KIKELEAQGYHFEGAEASFELLVRDMLGKRKKYFEFLGFTVMTIKNRDEESFSEATVKVR
VPDEVAKRLGHDEPFEHTAAEGEGPVEALDRAVRKALEKFYPSLKDTKLTDYKVRILNEQ
AGTKATTRVLIESSDGKRRWGTVGVSPNIIEASWTALLESLEYKLHKDEEEMRNDEEN
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
ttgagtataaaggtctacgatacaacgctcagggacggtgcgcaggcctttggagtttct
ttctcactcgaagataagatcagaattgccgaggcactcgatgacctcggtgttcactat
cttgaagggggttggcctggctccaacccgaaggatatagcgttttttgaagctgtaaaa
ggtatgaacttcaagaatctgaaagtggcggccttcagttccacaagaaggcccgacgta
aaaatagaagaagacgcgaacattcagaccctcataaaagcggaaacacctgtttacacg
atctttggaaagagctgggatcttcacgtggaaaaagccttgcgaacgacactcgaagag
aatctgaagatgatatacgacacagtttcatatctcaaaagattcgccgatgaggtgata
tacgacgcggaacacttcttcgatgggtacaaggcgaacagagagtacgccctcaaaact
ctgaaggtggctgaagaagcgggggctgattgtctcgttctcgctgacacgaacggtgga
acgcttccacacgagatcgaggagatcatcgaggatgtgaaaaagcacgtgaaagctccg
ctcggaatacacgctcacaacgattcggatgtggcggtggcgaatacactcgtggctgtg
agaaagggagccgtgcacgtccaggggaccataaacggccttggagagagatgtggaaac
gcgaatctctgttcggtgattccgaatctcgttctcaagatggggcttgaggttatacca
aaggaaaacttgaagaagctcttcgatgtggcacacctcgttgcggaactctccggaaga
ccccacatcgagaacatgccttacgtaggtgattacgccttcgctcacaagggaggagtt
catgtttctgccataaaacgcgatccaaggacttacgaacacatcgacccggaactcgtg
gggaacagaaggatcatatccatctcggaactttccggtaagagcaacgtgctggagaag
ataaaggaaatgggattcgaaatagatgagtcatcgcccaaggtcagggagatcctcaaa
aagatcaaggaattggaagcgcaggggtaccacttcgagggtgcggaggcatctttcgag
cttctcgtcagggatatgctcgggaaaagaaagaagtactttgagtttctcggtttcacc
gtgatgaccataaagaacagggatgaggagagtttctccgaagcaaccgtgaaagtcaga
gtcccggacgaagttgcgaagagactgggacacgacgaaccctttgaacacacagcagcg
gaaggagaaggaccggtagaagcgctcgacagagcggtgagaaaagccctcgagaaattc
tatccatctttgaaagacacgaaactcacggactacaaggtgagaatcctgaacgagcag
gcgggcaccaaagcgacaacacgggttctcatagagtccagcgatggaaagagaaggtgg
ggaactgtgggcgtctcaccgaacatcatagaggcttcctggaccgctcttctcgaatcc
ttagagtacaagcttcacaaggatgaagaggagatgagaaacgatgaggagaattaa
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