Treponema pallidum subsp. pallidum Chicago: TPChic_0500
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Entry
TPChic_0500 CDS
T01868
Symbol
mrdA
Name
(GenBank) penicillin-binding protein 2
KO
K05515
penicillin-binding protein 2 [EC:
3.4.16.4
]
Organism
tph
Treponema pallidum subsp. pallidum Chicago
Pathway
tph00550
Peptidoglycan biosynthesis
tph01100
Metabolic pathways
tph01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
tph00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TPChic_0500 (mrdA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
TPChic_0500 (mrdA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tph01011
]
TPChic_0500 (mrdA)
Enzymes [BR:
tph01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
TPChic_0500 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:
tph01011
]
Peptidoglycan biosynthesis and degradation
DD-Transpeptidase (Class B PBP)
TPChic_0500 (mrdA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transpeptidase
PBP_dimer
DUF4851
Motif
Other DBs
NCBI-ProteinID:
ADD72612
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Position
535530..537404
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AA seq
624 aa
AA seq
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MRYFSLLPDRHMLFRIKVLTWLVVLVMLLYMRQLFVIQIVRGDSFKKKSLNISQRSKVIP
AQRGEIFDRHADLPMVLNVNSFAVDMIPGEVPPEQFDTVLNKLSHILRVPISDIRKKIPD
AVRRSFQTVELRSNVSYEDITAIAQIIDELPGVSWYSKPVRNYVETGSFAHVIGYVGEIT
KEELKRFYSKGYRPNSLIGKAGIEKEYDEVLRGKEGHEYRTVDARGRYIENTSVTNPPRM
GNNLVLTIDRRIQKLAEDALGPRIGAAVVLKPTTGEVLAMVSYPYFDQNIFTQHNAHELY
AQLSHDTRFPLLNRVVNASYPPASTFKIVMSTAILAEKAFPHEKTVDCPGEIEYGNRLFR
CHIRKPGHGKVDLRRALEQSCDIYYWTVCRDYLGIDRMISYINDFGFGKSARIDLPSQTE
GMVPTPKWKERRFHEKWLDGDTMNLAIGQGYMLVSPLQVANMVAMTVNNGVIYRPHLLKE
IRDSRTNEVLFRHKPEVLKTAKIPAEIFEHVRADMHSVVTRGSSQYAMKNKTVSLAGKTG
TAEVGFHNRWHSWMAAYGPYHRPPDEAVVVVVLVEARNEWEWWAPFATNIIFQGIFANED
YEQAVESLKSYGISLGVPARSRQE
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atgcgttatttttctctccttcctgatcgtcatatgctttttaggataaaggttctcacc
tggctcgtcgtgctggttatgctgttgtacatgcggcagctgtttgtcattcaaatcgtg
cggggggattcgttcaaaaaaaaatcgctgaacatatctcagcgtagtaaagtaattcct
gcacaacggggggagatttttgatcgccacgcggatctgcccatggtgctgaatgtcaat
tcgtttgcagttgatatgatccccggagaggttccgcctgagcagttcgatacggtgctc
aacaaattgtcgcatattctgcgcgtacctatttcggatattcgaaagaaaattcctgat
gcggtccgccgttcatttcaaacggtggagttgcgcagtaacgtgagttacgaggacatc
actgctatcgcccaaataattgatgaactgccgggcgtttcttggtattcaaaaccagta
cgaaattacgttgaaacaggatcattcgctcacgttatcggatatgtgggggagattaca
aaagaagagctcaaacgattttacagtaaagggtacaggcccaacagtctcattggaaag
gctggaattgaaaaagaatacgacgaggtcctgagagggaaagagggacacgagtaccgg
accgtcgatgcccgtgggcgatacatagaaaacacttcggttactaaccctcctcgcatg
ggtaataacctcgtgctcaccatcgatcggcgtatacaaaaacttgcagaagacgcgctc
ggtcctcgtatcggagcggcagtggtactgaaaccgacaacgggagaagtacttgctatg
gtatcttatccgtactttgaccaaaacattttcactcagcataacgcccacgaactgtat
gcgcagctttcacatgatacacggttccctctgcttaaccgtgttgtgaatgcaagttac
ccgcctgcgtcgacgttcaagattgtcatgtcaaccgctattttggcagagaaggcattc
ccccatgaaaagacggtggactgtccaggagagatcgagtatggcaatcgcttatttcgc
tgtcatatcagaaagcctgggcacggcaaggtagatctccgtcgtgcgcttgagcagtcg
tgtgatatttattactggacagtctgtcgagactatcttggcatcgaccgcatgatttcg
tacatcaacgattttggatttggcaaatcggcgcgcatcgatttacccagtcaaacagag
ggtatggttccaacaccgaaatggaaagaacgtcggtttcatgaaaaatggttggatgga
gacactatgaatctcgctatcgggcagggttacatgcttgtctcgcctctgcaggtggca
aacatggtcgcgatgaccgttaacaatggcgtcatttatcggccccatttactcaaggaa
attcgggactctcgtactaacgaagtgctatttaggcataaacctgaggtattaaagaca
gcaaaaattcctgcagagatattcgagcacgtgcgcgcagatatgcattcggttgtcacg
cgtggctcctcccagtatgcaatgaaaaataagaccgtgtccctggcagggaaaactggt
actgcagaagtaggttttcacaatcggtggcattcgtggatggcagcgtatgggccttat
catcgccccccggatgaagcggtggtcgttgtggtactggtagaggcaagaaacgaatgg
gaatggtgggcgccgtttgcaaccaatatcatttttcagggtatttttgcgaatgaggat
tatgagcaagcagttgagtcgctcaagtcgtacggcatttcccttggggtgccggcaagg
agtcggcaggaatga
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