Thermobaculum terrenum: Tter_0193
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Entry
Tter_0193 CDS
T01134
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ttr
Thermobaculum terrenum
Pathway
ttr00290
Valine, leucine and isoleucine biosynthesis
ttr00620
Pyruvate metabolism
ttr01100
Metabolic pathways
ttr01110
Biosynthesis of secondary metabolites
ttr01210
2-Oxocarboxylic acid metabolism
ttr01230
Biosynthesis of amino acids
Module
ttr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ttr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tter_0193
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tter_0193
Enzymes [BR:
ttr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tter_0193
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
PEP_mutase
Asparaginase_C
DUF2102
CutC
Motif
Other DBs
NCBI-ProteinID:
ACZ41115
UniProt:
D1CDV9
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All DBs
Position
1:206278..207876
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AA seq
532 aa
AA seq
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MRQIKIYDTTLRDGSQMEGISFSVEDKLKLTRRLDELGVHYIEGGWPGSNPKDAEYFERM
KNIPLKNAKLAAFGSTRRAYASVEEDLNLRMLIEAGTPVITLVGKSWDMQVHVVLGCSLE
ENLAMIKDSIAFCKSYGKEVFFDAEHFFDGYKNNPDYAMRCIHAAIEAGADAVVLCDTNG
GRMPEEIAQAVEKVVEETRAIAATRPFDVGIHTHNDSELAVANTLIAVQKGATQVQGTIN
GYGERIGNANLCSIIANLELKYGYHTIGREKVKELTSVSRYFAEVANMAHDERLPYVGAK
AFTHKAGLHVNAVAKSAETYEHLPPELVGNTRRVTISELGGRSNVLMKMAQFGLEAHTSS
EQVRQVLEEVKRLEKEGFQFEDAEASFELLVLRAQPDYEPPFRLLDFMVVSESRNGGEFL
SEATVKIKVGNEVMHTAADGDGPVNALDRAMRKALAPFYPELDPVHLTDYKVRVLDNESG
TAATVRVWIQSTDGKSTWNTVGSSTNIIEASWLALADSLEYPLRSISKRRLR
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
ttgagacagataaagatctatgacactactttaagagatggctctcaaatggaggggatt
tccttctctgtcgaggacaagctgaagttgacaaggcgcctcgacgagcttggagttcat
tacattgaggggggctggccaggttccaatcctaaggacgccgaatactttgagaggatg
aagaacattcctctcaagaatgctaagctggcagctttcggctcaacgcgaagagcatac
gcatccgttgaggaagacctgaacctgaggatgctgatcgaagctggcactccagtcata
actctggtaggcaagagttgggacatgcaggtacacgtggtgctaggttgctcgttagaa
gagaacctagctatgatcaaagattccatagcattctgtaagtcctacggcaaggaagta
ttctttgatgcagagcacttctttgacggatacaagaataatcctgactacgctatgcga
tgtatacacgcggctatagaggctggggcggatgctgtagtgctgtgcgataccaacggg
ggtagaatgcccgaggagatagcgcaggccgttgagaaggtcgtagaagagacgagagca
atagcagcgacaaggccctttgacgtcggcatacacacccacaacgactctgaattggca
gtagccaacaccttgatagccgtgcaaaaaggcgctacccaggtccaagggactataaat
ggctatggtgagcgtataggcaatgctaacctctgctcgataatagccaatctggaactg
aaatacggttaccacactattggccgagaaaaggtaaaggagcttacgtctgtctcaagg
tacttcgctgaagtagctaacatggctcatgacgaaagactaccctatgttggggcaaaa
gcctttacacataaagctgggctgcatgtcaacgctgtagccaaatcggctgagacttac
gaacacctaccacctgagctagtcggaaacaccaggcgagtaactatatccgagctgggt
ggtagatccaacgtactcatgaagatggctcagttcggactggaggcgcatacctcctcg
gaacaggtaagacaggtgctcgaagaggtaaaaaggcttgaaaaagagggttttcaattc
gaagatgctgaagcctcattcgaactgctggttcttcgagcacagccagactatgaacca
ccatttaggctactggatttcatggtcgtatccgagagccgtaatggcggcgagtttctg
tccgaggcaactgtgaagatcaaggtaggtaacgaagtgatgcacacagcggcagatggg
gacggccctgtaaatgccttggacagggctatgcgcaaggcacttgcgccattctatcca
gaacttgatccagtacaccttacggactataaggtacgagtattggataacgaatctgga
actgctgctacagtacgcgtatggatccagtccactgacggtaagagcacttggaatacc
gttggttcttcaaccaacattattgaagctagctggttggcgcttgctgatagcttggag
tatccactccgatcaatcagcaagcgtaggctaagataa
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