KEGG   Tupaia chinensis (Chinese tree shrew): 102477532
Entry
102477532         CDS       T02978                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00230  Purine metabolism
tup01100  Metabolic pathways
tup01522  Endocrine resistance
tup04015  Rap1 signaling pathway
tup04020  Calcium signaling pathway
tup04022  cGMP-PKG signaling pathway
tup04024  cAMP signaling pathway
tup04062  Chemokine signaling pathway
tup04072  Phospholipase D signaling pathway
tup04114  Oocyte meiosis
tup04211  Longevity regulating pathway
tup04213  Longevity regulating pathway - multiple species
tup04261  Adrenergic signaling in cardiomyocytes
tup04270  Vascular smooth muscle contraction
tup04371  Apelin signaling pathway
tup04540  Gap junction
tup04611  Platelet activation
tup04713  Circadian entrainment
tup04714  Thermogenesis
tup04723  Retrograde endocannabinoid signaling
tup04724  Glutamatergic synapse
tup04725  Cholinergic synapse
tup04727  GABAergic synapse
tup04740  Olfactory transduction
tup04750  Inflammatory mediator regulation of TRP channels
tup04911  Insulin secretion
tup04912  GnRH signaling pathway
tup04913  Ovarian steroidogenesis
tup04914  Progesterone-mediated oocyte maturation
tup04915  Estrogen signaling pathway
tup04916  Melanogenesis
tup04918  Thyroid hormone synthesis
tup04921  Oxytocin signaling pathway
tup04923  Regulation of lipolysis in adipocytes
tup04925  Aldosterone synthesis and secretion
tup04926  Relaxin signaling pathway
tup04927  Cortisol synthesis and secretion
tup04928  Parathyroid hormone synthesis, secretion and action
tup04934  Cushing syndrome
tup04935  Growth hormone synthesis, secretion and action
tup04962  Vasopressin-regulated water reabsorption
tup04970  Salivary secretion
tup04971  Gastric acid secretion
tup04972  Pancreatic secretion
tup04976  Bile secretion
tup05032  Morphine addiction
tup05163  Human cytomegalovirus infection
tup05166  Human T-cell leukemia virus 1 infection
tup05200  Pathways in cancer
tup05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102477532 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102477532 (ADCY3)
   04371 Apelin signaling pathway
    102477532 (ADCY3)
   04020 Calcium signaling pathway
    102477532 (ADCY3)
   04072 Phospholipase D signaling pathway
    102477532 (ADCY3)
   04024 cAMP signaling pathway
    102477532 (ADCY3)
   04022 cGMP-PKG signaling pathway
    102477532 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    102477532 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102477532 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102477532 (ADCY3)
   04062 Chemokine signaling pathway
    102477532 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    102477532 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    102477532 (ADCY3)
   04912 GnRH signaling pathway
    102477532 (ADCY3)
   04913 Ovarian steroidogenesis
    102477532 (ADCY3)
   04915 Estrogen signaling pathway
    102477532 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    102477532 (ADCY3)
   04921 Oxytocin signaling pathway
    102477532 (ADCY3)
   04926 Relaxin signaling pathway
    102477532 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    102477532 (ADCY3)
   04918 Thyroid hormone synthesis
    102477532 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    102477532 (ADCY3)
   04916 Melanogenesis
    102477532 (ADCY3)
   04925 Aldosterone synthesis and secretion
    102477532 (ADCY3)
   04927 Cortisol synthesis and secretion
    102477532 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102477532 (ADCY3)
   04270 Vascular smooth muscle contraction
    102477532 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    102477532 (ADCY3)
   04971 Gastric acid secretion
    102477532 (ADCY3)
   04972 Pancreatic secretion
    102477532 (ADCY3)
   04976 Bile secretion
    102477532 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    102477532 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    102477532 (ADCY3)
   04727 GABAergic synapse
    102477532 (ADCY3)
   04725 Cholinergic synapse
    102477532 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    102477532 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    102477532 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    102477532 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    102477532 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    102477532 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102477532 (ADCY3)
   04714 Thermogenesis
    102477532 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102477532 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    102477532 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    102477532 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102477532 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102477532 (ADCY3)
   05163 Human cytomegalovirus infection
    102477532 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102477532 (ADCY3)
Enzymes [BR:tup01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     102477532 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA NCE101 Peptidase_S49_N
Other DBs
NCBI-GeneID: 102477532
NCBI-ProteinID: XP_006147299
LinkDB
Position
Un
AA seq 1145 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDMLAPLAVAAVGLVLDIL
LFVLCKKGLLPDRVTRKVVPYLLWLLISAQIFSYLGLNFARAHAASDTVGWQAFFVFSFF
ITLPLSLSPIVLISVVSCVIHTLVLGVTVAQQQQDQLKGMQLLREILANVFLYLCAIIVG
VMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCD
YLDEKGIETYLIIASKPEVKKTATQNGINGSALPNGVPTSSKPGSPALIETKEPNGSAQT
SGSTSEEPEEPDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAMVEILIDPWLMTN
YVTFAVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDHTRWARNTWAMLAIFILVMAN
VVDMLSCLQYYAGPSNGTAGVELEDGCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM
LLVTGAVAAINLYAWCPVFDDYDHKRFQEHGFPVVALEKMQVLSPSGLNGTDRLPLVPSK
YSMTVMMFIMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPAAFPNGSSITLPHQ
VVDNP
NT seq 3438 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctcggagcccgagtactccgccgagtactccgccgagtac
tccgtcagcctgccctctgaccccgaccggggtgtgggccggacccatgagatctccgtg
cggaactcgggctcctgcctgtgcctgccccgcttcatgcggctgaccttcgtgcccgag
tccttggagaacctctaccagacctacttcaagaggcagcgccacgagaccttgctggtg
ctggtggtcttcgccgccctcttcgactgctacgtggtggtcatgtgcgccgtggtcttc
tccagcgacatgctggctcccctggccgtggccgccgtcgggctggtcttggacatcctc
ctcttcgtgctctgcaagaagggcctgctcccggaccgcgtcacccgcaaggtggtgccc
tacctgctgtggctgctcatctccgcgcagatcttctcttacctgggcctgaacttcgcc
cgcgcgcatgccgccagcgacacggtgggctggcaggccttctttgtcttctccttcttc
atcacgctgcccctcagcctcagccccatcgtcctcatctcggtggtctcctgtgtgatc
cacacgctggtcttgggagtcacggtggcccagcagcagcaggaccagctgaaggggatg
cagttgctaagagagatcctggccaacgtcttcctgtacctgtgtgccatcatcgtgggc
gtcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaacctcatgctt
tccatcctgcccaagcacgtggccgacgagatgttgaaggacatgaagaaagacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc
ctcttcgccgacatcgtgggcttcacgcagctgtcctctgcctgcagcgcccaggagctg
gtgaagctgctcaacgagctctttgcccgcttcgacaagctggcggccaaataccaccag
ctgcggatcaagatcctgggcgactgctactactgcatctgcggcctgcccgactaccgg
gaggaccacgccgtgtgctccatcctcatggggctcgccatggtcgaggccatctcgtat
gtgcgggagaagaccaagaccggtgtggacatgcgtgtgggggtgcacacgggcaccgtg
ctgggtggcgtcctgggccagaagcgctggcagtatgacgtgtggtctacggatgtcacc
gtggccaacaagatggaggctggcggcatccctgggcgcgtgcacatctcccagagcacc
ctggactgcctgaaaggagagttcgacgtggagccgggtgatgggggcagccgctgcgat
tacctagatgagaagggcattgaaacctacctcatcattgcctccaagccagaggtgaag
aaaaccgccacccaaaatggcatcaatggctcggccctgccaaatggagtaccaacttcc
tctaagcccggctcccctgccctcattgaaacgaaggagcccaacgggagtgcccaaacc
agtggctccacgtcggaggagcccgaggagccggatgcccaggccgacaacccctcgttc
cccaaccctcgccggaggctgcgccttcaggacctggcggaccgggtggtggatgcctct
gaggacgaacacgagctcaaccagctgctcaacgaggccctgcttgagcgagagtcggcc
caggtggtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagatg
gaaactcgctactcggtggagaaggaaaagcagagtggagccgccttcagctgctcctgc
gtcgtcctgctctgcacagccatggtggagatactcatcgacccctggctgatgacaaac
tatgtgaccttcgcggttggggagattctgctcctgattctgaccatctgctcactggct
gccatctttccccgggcctttcctaagaagcttgtggccttctcgacgtggatcgatcac
acccgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcgaat
gtcgtggacatgctcagctgtctccagtactacgcgggacccagcaacgggacagcaggg
gtggagctggaggatggctgcctggagaaccccaagtactacaactatgtggctgtgctg
tcgctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg
ctgcttgtcacgggcgctgtggctgccatcaacctctatgcctggtgccccgtctttgat
gactacgaccacaaacgttttcaggaacatggctttccagtggtggccttagagaagatg
caggtgttgtccccctctgggctcaatggcactgacaggctgcccctggtgccttccaag
tactcgatgacagtgatgatgttcatcatgatgctgagcttctactacttctcccgccac
gtggaaaaactggcacggacactgttcttgtggaagattgaggtccacgaccagaaggaa
cgtgtctatgagatgcgacgctggaacgaggccttggtcaccaacatgctacccgagcat
gtggctcgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttac
gacgagatcggagtcatgtttgcctccctgcccaactttgctgacttctacacggaggag
agcatcaacaacggtggcattgaatgtctgcgcttccttaatgagatcatctcagacttt
gactctctcctggataaccccaaattccgggtcatcaccaagatcaaaaccattggcagc
acctatatggcagcctcaggagtcaccccagatgtcaacactaacggatttaccagctcc
agcaaggaggaaaagtcagacaaggagcgctggcagcacctggccgacctggccgacttc
gcgctagccatgaaggatacgctcacaaacatcaacaatcagtccttcaacaacttcatg
ctgcgcataggcatgaacaaaggaggggtcctggctggtgtcattggagcccggaaacca
cactatgacatctggggcaacacagtcaacgtcgccagcaggatggagtctacaggggtc
atgggcaacattcaggttgtggaagagacacaagccatcctccgagagtatggcttccgc
tttgtgaggcgaggccccatctttgtgaaagggaagggggagctgctgaccttcttcctg
aaggggcgagataagcctgctgccttccccaatggctcctccatcacactgccccaccag
gttgtggacaacccctga

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