KEGG   Tupaia chinensis (Chinese tree shrew): 102494607Help
Entry
102494607         CDS       T02978                                 

Gene name
HKDC1
Definition
(RefSeq) hexokinase domain containing 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00010  Glycolysis / Gluconeogenesis
tup00051  Fructose and mannose metabolism
tup00052  Galactose metabolism
tup00500  Starch and sucrose metabolism
tup00520  Amino sugar and nucleotide sugar metabolism
tup00524  Neomycin, kanamycin and gentamicin biosynthesis
tup01100  Metabolic pathways
tup01200  Carbon metabolism
tup04066  HIF-1 signaling pathway
tup04910  Insulin signaling pathway
tup04930  Type II diabetes mellitus
tup04973  Carbohydrate digestion and absorption
tup05230  Central carbon metabolism in cancer
Module
tup_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
tup_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:tup00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102494607 (HKDC1)
   00051 Fructose and mannose metabolism
    102494607 (HKDC1)
   00052 Galactose metabolism
    102494607 (HKDC1)
   00500 Starch and sucrose metabolism
    102494607 (HKDC1)
   00520 Amino sugar and nucleotide sugar metabolism
    102494607 (HKDC1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    102494607 (HKDC1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    102494607 (HKDC1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    102494607 (HKDC1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102494607 (HKDC1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    102494607 (HKDC1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102494607 (HKDC1)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     102494607 (HKDC1)
Membrane trafficking [BR:tup04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    102494607 (HKDC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 CSD
Motif
Other DBs
NCBI-GeneID: 102494607
NCBI-ProteinID: XP_006148993
UniProt: L9KTB3
LinkDB All DBs
Position
Un
AA seq 911 aa AA seqDB search
MFAVHLMAFYFTKLKEDQIKKVDRFLYHMRLSDETLLDIMARFQVEMEKGLAKDTNPTAS
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESLFYPTPNEIIT
GNGSELFDYVADCLVDFMKTKELKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLAKALKKHKDLDVDILALVNDTVATMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRMNKKLDRLRTTVGMDGTVYKIH
PQYPKRLHKVVRKLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT
REQLVGVQDKMRTELENGLKRKTHPMATVKMLPTYVRGMPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT
FSFPCRQASIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI
RTQYDKEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKHGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPKCDVTFILSEDGSGKGA
ALITAVAKRLQ
NT seq 2736 nt NT seq  +upstreamnt  +downstreamnt
atgtttgcagtacacttgatggcgttttacttcaccaagctgaaggaggatcagatcaag
aaggtggacaggttcctgtatcacatgcggctctccgatgagacacttttggacatcatg
gcacggttccaggtggagatggagaagggcctggcaaaggacaccaaccctacagcctca
gtgaagatgctgcctacctttgtcagggccattccagatggctcagaaaatggggagttc
ctgtccctggatcttggtggatccaagtttcgagtgttgaaggtgcaagtctctgaagaa
gggaagcgaaacgtccagatggagagtctgttctacccaacgcccaacgaaatcatcact
ggcaacggctcggagctgtttgactatgtagctgactgtctggtggactttatgaaaacc
aaagagttgaagcacaagaaattgcccctgggcctaaccttttcttttccttgccggcag
actaaattggaggagggtgtcttgctttcgtggacgaagaagtttaaggcacgaggagtt
caggacacagatgtagtgagccgcctggccaaagccttgaagaaacacaaggacctggat
gtggacatcttggccttggtcaatgacacggtggcgaccatgatgacatgcgcctatgat
gatccctactgcgaagtcggtgtcatcattggaactggcaccaacgcctgttacatggag
gacatgagcaacatcgacctcgtggaaggtgacgaggggaggatgtgcatcaacacggag
tggggggccttcggagacgatggggccttggaagacatccgcaccgagtttgacagggag
ctggaccttggctctctcaacccagggaagcagctgttcgagaaaatgatcagtggcctg
tacctgggagagcttgtcagactcatcttactgaagatggccaaggctggcctcctgttt
ggtggtgagaaatcctccgctctccacactaagggcaagattgagacacggcatgtggct
gccatggagaagtataaagaaggccttgccaatacaagagagatcctggtggacctgggc
ctggagccctctgaggctgactgcattgccgtccagcacgtctgtactattgtctctttc
cgctctgccaacctctgtgcagcggccctggcggccatcctaacgcgcctccggatgaac
aagaagctagaccggctccggaccacagtgggcatggatggcacagtgtataagatacac
cctcagtatccaaaacgcctacacaaggtggtgagaaaactggtcccaaactgtgatgtc
cgcttcctcctgtcagagagtggcagcaccaagggggcagccatggtgactgcagtggcc
tcccgtgtgcaggcccagcggaagcagattgacaaggtgctagctttgttccagctgacc
cgtgagcagcttgtgggtgtgcaggacaagatgcggactgagctcgagaatgggctgaag
aggaagacccacccgatggccacagtcaagatgctgcctacttatgtccgtgggatgcca
gacggcacagagaaaggaaaattcctcgccctggatctgggaggcactaacttccgtgtc
ctcctggtgaagatcagaagcggacggaggtcggtgcgaatgtacaacaagatcttcgcc
atccccttggagatcatgcagggcacaggcgaggagttgttcgaccacattgtgcagtgc
attgccgacttcctggactacatgggcctcaagggagcccagcttcccttgggcttcaca
ttctcatttccttgcaggcaggcgagcatcgacaagggaacactcataggatggaccaaa
ggcttcaaggccactgactgtgaaggagaagacgtggtagacatgctcagggaagccatc
aagaggagaaatgagtttgacctggacatagttgcagtcgtgaatgacacagtggggacc
atgatgacctgtggctatgaagatcctaactgtgagattggcctgattgcaggaacgggc
agcaacatgtgctacatggaggagatgaggaacattgagctggtggaaggagacgaaggg
aagatgtgcatcaacacagagtggggaggatttggggacaatggctgcatagatgacatc
cggacccagtacgacaaggaggtggatgaggggtccttgaatcctggcaagcagagatac
gagaaaatgaccagtgggatgtacctgggggagatcgtgcggcagatcctgattgacctt
accaagcacggtctcctcttccgagggcagatttcagagcgtctccggaccaggggcatc
ttcgaaactaagttcctgtcccagatcgaaagcgaccggctggccctcctccaggtcagg
aggatcctgcagcagctgggcctggacagcacatgtgaggacagcatcgtggtgaaggag
gtgtgtggagctgtgtcccggcgggcagcccagctctgtggcgctggcttggccgccatt
gtggagaaaagaagggaagaccagggtctggagcacctgaggatcaccgtgggtgtggat
ggcaccctgtacaagctgcaccctcacttttctcggatattgcaagagaccgtgaaagaa
ctagcccctaaatgtgatgtgactttcatactatcggaagacggcagtggaaagggagca
gctctgatcacagctgtggccaagagactgcagtag

DBGET integrated database retrieval system