Ursus arctos horribilis (North American brown bear): 113256389
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Entry
113256389 CDS
T05909
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah00260
Glycine, serine and threonine metabolism
uah00630
Glyoxylate and dicarboxylate metabolism
uah00670
One carbon pool by folate
uah01100
Metabolic pathways
uah01200
Carbon metabolism
uah01230
Biosynthesis of amino acids
uah01240
Biosynthesis of cofactors
uah01523
Antifolate resistance
Module
uah_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
113256389 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
113256389 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
113256389 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
113256389 (SHMT2)
Enzymes [BR:
uah01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
113256389 (SHMT2)
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Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
113256389
NCBI-ProteinID:
XP_026355992
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All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGQLVRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGTEVVDEVELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRVSATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVRAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGTRAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLAVKSKTAKLQDFKSFLLKDPETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcagctggtc
aggatggccatccggtgccagcacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaggagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagaggtactacggaggcacagaggtagtggatgaagttgagctgctgtgtcag
cgcagggccttagaggccttcgacctggatcccgcgcagtggggagtcaatgtgcagccg
tactcgggctcgccggctaatctggccgcctacacggccctcctgcagccccatgaccga
atcatggggctggacttgcccgatgggggccatctgactcacggctacatgtctgatgtc
aagcgggtctcagccacgtccatcttctttgagtccatgccctataagctcaatcctaaa
accggcctcatcgactacgaccagctggcgctgactgcgcggctcttccgcccgcggctc
attattgctggtaccagtgcctacgcgcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaagtcagggcacacctactggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcatgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtctggactcatcttctaccggaaggggactcgggctgtggac
cccaagactggccgggagatcccgtacacatttgaggaccgaatcaactttgccgtgttc
ccatccctgcagggggggccccacaaccatgccattgctgccgtggctgtggccctaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggctgatgccctgctagagcgaggctactcgctcgtgtctggtggcaccgacaaccac
ctagtgctcgtggatctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaactggtgtccatcacagccaacaagaacacctgtcctggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccctgacctctcgacagttccgcgaggatgac
ttccggagagttgtggacttcatagatgaaggtgtcagcatcggcttggcggtgaagagc
aagactgccaaactccaggatttcaaatccttcctgctcaaggacccagaaacaagtcat
cggctggctgacctcaggcaacgggtggagcagtttgccagggccttccccatgcctggt
tttgatgagcgctga
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