KEGG   Ursus arctos horribilis: 113265422
Entry
113265422         CDS       T05909                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
uah  Ursus arctos horribilis
Pathway
uah01521  EGFR tyrosine kinase inhibitor resistance
uah04062  Chemokine signaling pathway
uah04066  HIF-1 signaling pathway
uah04068  FoxO signaling pathway
uah04217  Necroptosis
uah04550  Signaling pathways regulating pluripotency of stem cells
uah04630  JAK-STAT signaling pathway
uah04659  Th17 cell differentiation
uah04917  Prolactin signaling pathway
uah04920  Adipocytokine signaling pathway
uah04931  Insulin resistance
uah04933  AGE-RAGE signaling pathway in diabetic complications
uah04935  Growth hormone synthesis, secretion and action
uah05145  Toxoplasmosis
uah05160  Hepatitis C
uah05161  Hepatitis B
uah05162  Measles
uah05163  Human cytomegalovirus infection
uah05167  Kaposi sarcoma-associated herpesvirus infection
uah05169  Epstein-Barr virus infection
uah05200  Pathways in cancer
uah05203  Viral carcinogenesis
uah05205  Proteoglycans in cancer
uah05206  MicroRNAs in cancer
uah05212  Pancreatic cancer
uah05221  Acute myeloid leukemia
uah05223  Non-small cell lung cancer
uah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
uah05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    113265422 (STAT3)
   04066 HIF-1 signaling pathway
    113265422 (STAT3)
   04068 FoxO signaling pathway
    113265422 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    113265422 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    113265422 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    113265422 (STAT3)
   04062 Chemokine signaling pathway
    113265422 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    113265422 (STAT3)
   04917 Prolactin signaling pathway
    113265422 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    113265422 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113265422 (STAT3)
   05206 MicroRNAs in cancer
    113265422 (STAT3)
   05205 Proteoglycans in cancer
    113265422 (STAT3)
   05203 Viral carcinogenesis
    113265422 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113265422 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    113265422 (STAT3)
   05221 Acute myeloid leukemia
    113265422 (STAT3)
   05223 Non-small cell lung cancer
    113265422 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    113265422 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    113265422 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    113265422 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    113265422 (STAT3)
   05161 Hepatitis B
    113265422 (STAT3)
   05160 Hepatitis C
    113265422 (STAT3)
   05163 Human cytomegalovirus infection
    113265422 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113265422 (STAT3)
   05169 Epstein-Barr virus infection
    113265422 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    113265422 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113265422 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:uah03000]
    113265422 (STAT3)
Transcription factors [BR:uah03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    113265422 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 113265422
NCBI-ProteinID: XP_026368588
UniProt: A0A3Q7X2U2
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctccagcagctcgacacacggtacctggagcagcttcatcag
ctgtacagtgacagcttcccgatggagctgcggcagtttctggccccttggattgagagt
caagattgggcatatgcggccagcaaagaatcacatgcgactttggtgtttcataatctc
ttgggtgagattgaccagcagtacagccgcttcctacaggagtcaaatgttctctatcag
cacaatctgcgaaggatcaagcagttccttcagagcagatatctggagaagccaatggag
attgcccgaatcgtggcccggtgcctatgggaagagtcccgcctgctccagactgcagcc
actgcagcccagcaagggggccaggccaaccaccccacagccgctgtggtgacggagaag
cagcagatgctggagcagcacctccaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtggagaatctccaggatgactttgatttcaactacaaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtcggtgaccaggcagaagatg
cagcagctggagcagatgctcaccgcgctggaccagatgcggcgcagcatcgtgagtgag
ttggcggggctgttgtccgcgatggagtatgtgcagaaaactctcacggacgaagagctg
gctgactggaagaggcggcagcagattgcgtgcatcgggggccctcccaacatctgccta
gatcgcctagaaaattggataacctcattagcagaatctcaacttcagacccgccagcaa
attaagaaactggaggagttgcagcaaaaagtgtcctacaaaggggatcccatcgtacag
caccggccgatgctggaggagaggatcgtagagctgttcagaaacttaatgaaaagtgcc
ttcgtggttgagcggcagccctgcatgcctatgcatcctgaccggcccttagtcatcaag
actggcgtccagttcactaccaaagtcagattgctggtcaaattccctgagttaaattat
cagcttaaaattaaagtgtgcattgacaaagactccggggatgttgcagccctcagagga
tcccggaaatttaacattctgggcacaaacacaaaagtgatgaacatggaagagtccaac
aacggcagcctgtctgcagaattcaaacacctgaccctgagagagcaaagatgtggtaac
gggggccgagccaattgtgacgcctccctgattgtcaccgaggagctgcacctgatcact
tttgagaccgaggtgtatcaccaaggcctcaagatcgaccttgagacccactccttgccg
gtcgtggtgatctccaacatctgtcagatgccaaatgcctgggcatcgatcctgtggtat
aacatgctgaccaacaaccccaagaacgtgaacttcttcaccaagcccccgattggcacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccacgaagcgagggctg
agcatcgagcagttgactacgctggcagagaaactcttaggacctggtgtgaactattca
gggtgtcagattacgtgggctaaattttgcaaagaaaacatggctggcaaaggcttctcc
ttctgggtttggctagacaatatcattgaccttgtgaaaaagtacatcctggctctttgg
aatgaagggtacataatgggttttatcagtaaggagcgagagcgggccatcttgagtacc
aagcccccaggcaccttcctgctacggttcagtgaaagcagcaaagaaggaggtgtcacc
ttcacttgggtggagaaggacatcagcggtaagacccagatccagtcggtggaaccatat
accaagcagcagctgaacaacatgtcgtttgctgaaatcatcatgggctataagatcatg
gatgccaccaacatcctggtgtctccgctggtctatctctaccccgacattcctaaggag
gaggcatttggaaagtactgtcgcccagagagccaggagcatcctgaagctgacccaggt
agtgctgccccgtacctgaagaccaagtttatctgtgtgacaccaacgacgtgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgagccctcagcaggagggcagttcgagtccctcacgttcgacatggag
ttgacctcggagtgcgctacctccccgatgtga

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