Ursus maritimus (polar bear): 103656833 Help Entry 103656833         CDS       T03271                                  Gene name TBK1 Definition (RefSeq) TANK binding kinase 1   KO K05410   TANK-binding kinase 1 [EC:2.7.11.10] Organism umr  Ursus maritimus (polar bear) Pathway umr04014   Ras signaling pathway umr04137   Mitophagy - animal umr04140   Autophagy - animal umr04620   Toll-like receptor signaling pathway umr04621   NOD-like receptor signaling pathway umr04622   RIG-I-like receptor signaling pathway umr04623   Cytosolic DNA-sensing pathway umr04657   IL-17 signaling pathway umr05014   Amyotrophic lateral sclerosis umr05022   Pathways of neurodegeneration - multiple diseases umr05135   Yersinia infection umr05160   Hepatitis C umr05161   Hepatitis B umr05162   Measles umr05163   Human cytomegalovirus infection umr05164   Influenza A umr05165   Human papillomavirus infection umr05167   Kaposi sarcoma-associated herpesvirus infection umr05168   Herpes simplex virus 1 infection umr05169   Epstein-Barr virus infection umr05170   Human immunodeficiency virus 1 infection umr05171   Coronavirus disease - COVID-19 Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     103656833 (TBK1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     103656833 (TBK1)    04137 Mitophagy - animal     103656833 (TBK1)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     103656833 (TBK1)    04621 NOD-like receptor signaling pathway     103656833 (TBK1)    04622 RIG-I-like receptor signaling pathway     103656833 (TBK1)    04623 Cytosolic DNA-sensing pathway     103656833 (TBK1)    04657 IL-17 signaling pathway     103656833 (TBK1)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     103656833 (TBK1)    05022 Pathways of neurodegeneration - multiple diseases     103656833 (TBK1)   09171 Infectious disease: bacterial    05135 Yersinia infection     103656833 (TBK1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     103656833 (TBK1)    05161 Hepatitis B     103656833 (TBK1)    05160 Hepatitis C     103656833 (TBK1)    05171 Coronavirus disease - COVID-19     103656833 (TBK1)    05164 Influenza A     103656833 (TBK1)    05162 Measles     103656833 (TBK1)    05168 Herpes simplex virus 1 infection     103656833 (TBK1)    05163 Human cytomegalovirus infection     103656833 (TBK1)    05167 Kaposi sarcoma-associated herpesvirus infection     103656833 (TBK1)    05169 Epstein-Barr virus infection     103656833 (TBK1)    05165 Human papillomavirus infection     103656833 (TBK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:umr01001]     103656833 (TBK1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:umr04131]     103656833 (TBK1) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.10  IkappaB kinase      103656833 (TBK1) Protein kinases [BR:umr01001]  Serine/threonine kinases: Other   IKK family [OT]    103656833 (TBK1) Membrane trafficking [BR:umr04131]  Autophagy   Xenophagy    Other xenophagy associated proteins     103656833 (TBK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like CEP63 DUF713 ubiquitin Motif Other DBs NCBI-GeneID:  103656833 NCBI-ProteinID:  XP_008682469 UniProt:  A0A384BJL2 LinkDB All DBs Position Un AA seq 729 aa AA seqDB search MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA ETSDILHRMTIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV IEPGRLAQHFPKTTEEDPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG VVCYACKIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWAHQE GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH FTEECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTSQCFDIEEEVSKYQDYTNELQETLPQ KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD GGLRNVDCL NT seq 2190 nt NT seq  +upstreamnt  +downstreamnt atgcagagcacgtctaatcatctgtggcttttatcggatattttaggccaaggagctact gcaaatgtctttcgtggaaggcacaagaaaaccggtgacttatttgctatcaaagtattt aataacataagcttccttcgtccagtggatgttcaaatgagagaattcgaagtgttgaag aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagag ccatctaatgcctatggactaccagagtctgaatttttaattgttttacgagatgtggtc ggtggaatgaatcatctccgagagaatggcattgtgcaccgtgatatcaagccaggaaat atcatgcgtgttataggggaggatggacagtctgtgtacaaactcacagattttggcgca gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg catcctgatatgtatgagagagcagtactgagaaaagatcatcagaagaaatatggagca acagttgatctttggagcattggggtaacattttaccacgcggctaccgggtcactgcca tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt ggagacatgcctatttcttgtagtctttctcggggtcttcaggttctacttacccctgtt cttgcaaacatcctggaggcagatcaggaaaagtgttggggttttgaccagttttttgca gaaactagtgatatacttcatcgaatgaccattcatgttttttcgctgcaacaaatgaca gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtgtat aaacaaaccaaaattatttcttcaaatcaagaacttatctatgagggacgacgtttagtc atagaacctggaagactggcacagcatttccctaaaactacggaggaagatcccatcttt gtagtaagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct aaagtacatccacgttacgatttagatggggacgctagcatggctaaggcaataacagga gttgtgtgttatgcctgtaaaattgccagtaccttgctgctttatcaggaattaatgcga aaggggatacgatggttgatagaattagtaaaagatgattataatgaaactgttcacaaa aagacagaagttgtgatcaccttggatttctgcatcagaaacattgaaaaaactgtgaaa gtatatgaaaagttgatgaagatcaatctagaagcagcagagttaggtgaaatttcagac atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag gatatcgaaagcaaattatctccaggtggattgctggcagatacctgggcccatcaagaa ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgctaaattgcatcaca gagatttactatcagttcaaaaaagacaaagcagaacgtcgattagcttataatgaagaa cagatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccac tttacagaggaatgtgttaagaaatatgaggcatttttggataagtcagaagaatggatg agaaagatgcttcatcttaggaaacagttattatccctaactagtcagtgttttgatatc gaagaagaagtatcaaagtatcaagactacacaaatgagttacaagaaactttgccccag aaaatgtttgcagcctccagtggaatcaagcataccatgaccccaatttatccatgttct aatacattagtggaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggta gttaaagaacttgctgaaaataatcatatcttagaaaggtttggctctttaaccatggat ggcggccttcgcaatgttgactgtctttag

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