KEGG   Ursus maritimus (polar bear): 103656833
Entry
103656833         CDS       T03271                                 

Gene name
TBK1
Definition
(RefSeq) TANK binding kinase 1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04014  Ras signaling pathway
umr04137  Mitophagy - animal
umr04140  Autophagy - animal
umr04620  Toll-like receptor signaling pathway
umr04621  NOD-like receptor signaling pathway
umr04622  RIG-I-like receptor signaling pathway
umr04623  Cytosolic DNA-sensing pathway
umr04657  IL-17 signaling pathway
umr05014  Amyotrophic lateral sclerosis
umr05022  Pathways of neurodegeneration - multiple diseases
umr05135  Yersinia infection
umr05160  Hepatitis C
umr05161  Hepatitis B
umr05162  Measles
umr05163  Human cytomegalovirus infection
umr05164  Influenza A
umr05165  Human papillomavirus infection
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05168  Herpes simplex virus 1 infection
umr05169  Epstein-Barr virus infection
umr05170  Human immunodeficiency virus 1 infection
umr05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103656833 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103656833 (TBK1)
   04137 Mitophagy - animal
    103656833 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103656833 (TBK1)
   04621 NOD-like receptor signaling pathway
    103656833 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    103656833 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    103656833 (TBK1)
   04657 IL-17 signaling pathway
    103656833 (TBK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103656833 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    103656833 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    103656833 (TBK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103656833 (TBK1)
   05161 Hepatitis B
    103656833 (TBK1)
   05160 Hepatitis C
    103656833 (TBK1)
   05171 Coronavirus disease - COVID-19
    103656833 (TBK1)
   05164 Influenza A
    103656833 (TBK1)
   05162 Measles
    103656833 (TBK1)
   05168 Herpes simplex virus 1 infection
    103656833 (TBK1)
   05163 Human cytomegalovirus infection
    103656833 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103656833 (TBK1)
   05169 Epstein-Barr virus infection
    103656833 (TBK1)
   05165 Human papillomavirus infection
    103656833 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103656833 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103656833 (TBK1)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     103656833 (TBK1)
Protein kinases [BR:umr01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   103656833 (TBK1)
Membrane trafficking [BR:umr04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    103656833 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like CEP63 DUF713 ubiquitin
Other DBs
NCBI-GeneID: 103656833
NCBI-ProteinID: XP_008682469
UniProt: A0A384BJL2
LinkDB
Position
Un
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMTIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
IEPGRLAQHFPKTTEEDPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACKIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWAHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTEECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTSQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacgtctaatcatctgtggcttttatcggatattttaggccaaggagctact
gcaaatgtctttcgtggaaggcacaagaaaaccggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaattcgaagtgttgaag
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttacgagatgtggtc
ggtggaatgaatcatctccgagagaatggcattgtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaggatggacagtctgtgtacaaactcacagattttggcgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtactgagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccacgcggctaccgggtcactgcca
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctatttcttgtagtctttctcggggtcttcaggttctacttacccctgtt
cttgcaaacatcctggaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcatcgaatgaccattcatgttttttcgctgcaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatctatgagggacgacgtttagtc
atagaacctggaagactggcacagcatttccctaaaactacggaggaagatcccatcttt
gtagtaagccgggaacctctgagtaccataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttacgatttagatggggacgctagcatggctaaggcaataacagga
gttgtgtgttatgcctgtaaaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagtaaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcaccttggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttgatgaagatcaatctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcaaattatctccaggtggattgctggcagatacctgggcccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgctaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtcgattagcttataatgaagaa
cagatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccac
tttacagaggaatgtgttaagaaatatgaggcatttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatccctaactagtcagtgttttgatatc
gaagaagaagtatcaaagtatcaagactacacaaatgagttacaagaaactttgccccag
aaaatgtttgcagcctccagtggaatcaagcataccatgaccccaatttatccatgttct
aatacattagtggaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggta
gttaaagaacttgctgaaaataatcatatcttagaaaggtttggctctttaaccatggat
ggcggccttcgcaatgttgactgtctttag

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