Ursus maritimus (polar bear): 103657101 Help Entry 103657101         CDS       T03271                                  Gene name FGF21 Definition (RefSeq) fibroblast growth factor 21   KO K22429   fibroblast growth factor 21 Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04714   Thermogenesis umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103657101 (FGF21)    04014 Ras signaling pathway     103657101 (FGF21)    04015 Rap1 signaling pathway     103657101 (FGF21)    04020 Calcium signaling pathway     103657101 (FGF21)    04151 PI3K-Akt signaling pathway     103657101 (FGF21)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103657101 (FGF21)  09150 Organismal Systems   09159 Environmental adaptation    04714 Thermogenesis     103657101 (FGF21)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103657101 (FGF21)   09162 Cancer: specific types    05226 Gastric cancer     103657101 (FGF21)    05218 Melanoma     103657101 (FGF21)    05224 Breast cancer     103657101 (FGF21)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103657101 (FGF21)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103657101 (FGF21) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103657101 (FGF21) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103657101 (FGF21) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103657101 NCBI-ProteinID:  XP_008682738 UniProt:  A0A384BJG4 LinkDB All DBs Position Un AA seq 209 aa AA seqDB search MGWDEARSEQLGLWVPVLAVLLLEACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQETEAH LEIRADGTVVGAARRSPESLLELKALKPGVIQILGVKTSRFLCQGPDGTLYGSLHFDPVA CSFRELLLEDGYNIYHSETLGLPLRLPAHNSPYRDLAPRGPARFLPLPGLLPVPPDPPGI LGPEPPDVGSSDPLSMVGPSQGRSPSYAS NT seq 630 nt NT seq  +upstreamnt  +downstreamnt atgggctgggatgaggccaggtccgagcagctggggctgtgggtccctgtgctggctgtc cttttgctggaagcttgccaggcacaccctatccctgactccagccccctcctccaattc ggaggccaagttcgacagcggtacctgtacacggacgatgcccaggagacagaggcccac ctagagatcagggctgatggcacagtggtgggggctgcccgccgcagcccagaaagtctc ttggagctgaaagccctgaaaccgggggtcattcaaatcctgggagtgaaaacatctagg ttcctgtgccagggcccagatgggacactgtacggatcgctccacttcgaccccgtagcc tgcagcttccgggaactgcttctggaggatgggtacaacatctaccactccgagaccctc ggcctcccacttcgcctgcccgcccacaactctccataccgggacttggcgccccggggg cctgcccgcttcctgcccctgccaggcctgcttccggtccccccggaccccccagggatc ctgggccccgagcctcccgacgtgggctcctcggaccccctgagcatggtggggccttcg cagggccgaagtcccagctacgcttcctga

Ursus maritimus (polar bear): 103658054 Help Entry 103658054         CDS       T03271                                  Gene name PDGFC Definition (RefSeq) platelet derived growth factor C   KO K05450   platelet derived growth factor C/D Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04072   Phospholipase D signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr04540   Gap junction umr04810   Regulation of actin cytoskeleton umr05215   Prostate cancer umr05218   Melanoma umr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103658054 (PDGFC)    04014 Ras signaling pathway     103658054 (PDGFC)    04015 Rap1 signaling pathway     103658054 (PDGFC)    04020 Calcium signaling pathway     103658054 (PDGFC)    04072 Phospholipase D signaling pathway     103658054 (PDGFC)    04151 PI3K-Akt signaling pathway     103658054 (PDGFC)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103658054 (PDGFC)    04540 Gap junction     103658054 (PDGFC)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103658054 (PDGFC)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     103658054 (PDGFC)   09162 Cancer: specific types    05218 Melanoma     103658054 (PDGFC)    05215 Prostate cancer     103658054 (PDGFC)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103658054 (PDGFC)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103658054 (PDGFC) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103658054 (PDGFC) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CUB PDGF Motif Other DBs NCBI-GeneID:  103658054 NCBI-ProteinID:  XP_008683757 UniProt:  A0A384BMF8 LinkDB All DBs Position Un AA seq 345 aa AA seqDB search MLLFGLLLLTSALAGQRHGTQAESNLSSKFQYSSNKEQNGVQDPQHERIITVSTNGSIHS PRFPHTYPRNMVLVWRLVAAEENVWIQLTFDERFGLEDPEDDICKYDFVEVEEPSDGTIL GRWCGSGTVPGKQISKGNQIRIRFVSDEYFPSEPGFCIHYNIVVPQFTEAVSPSVLPPSA LPLDLLNNAVTAFSTLEDLIRYLEPDRWQLDLEDLYRPTWQLLGKAFVFGRKSRVVDLNL LKEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSK VTKKYHEVLQLRPKSGVRGLHKSLTDVALEHHEECDCVCRGHTGG NT seq 1038 nt NT seq  +upstreamnt  +downstreamnt atgctcctcttcgggcttctcctgctgacatctgccctggccggccagagacacgggact caggctgagtccaacctgagtagtaaattccagtactccagcaacaaggaacagaacgga gtacaagatccccagcatgagagaattattactgtgtctactaatggaagtattcacagc ccaagatttcctcatacttacccaagaaatatggtcttggtatggagactggtagcagca gaggaaaatgtatggatacaacttacatttgatgaaagatttgggcttgaagacccagaa gatgacatatgcaagtatgatttcgtagaagttgaagaacccagtgatggaacgatatta gggcgttggtgtggttctggtactgtgccaggaaaacagatttctaaaggaaatcaaatc aggataagatttgtatctgatgaatattttccttctgaaccagggttctgcatccactac aacattgtcgtgccacaattcacagaggccgtgagcccttccgtgttacccccttcagct ttgccactggatctgcttaataacgctgtcactgcgtttagtaccttggaagatctcatt cggtatcttgaaccagacagatggcagttggacttggaagatctatataggccaacttgg caacttcttggcaaggcttttgtttttggaagaaaatccagagtggtggacctgaacctt ctaaaggaggaggtaagactgtacagctgcacgccccgtaacttctcggtgtccataagg gaagagctaaagagaaccgataccattttctggccaggttgtctcctggttaaacgctgt ggtggaaactgtgcttgctgtctccacaactgcaatgagtgtcagtgtgtcccgagcaaa gtcactaaaaaatatcatgaggtccttcagttgagaccaaagagtggggtccggggattg cataaatctctcacggacgtggccctggagcaccacgaggagtgtgactgtgtgtgcaga gggcacacgggaggataa

Ursus maritimus (polar bear): 103658669 Help Entry 103658669         CDS       T03271                                  Gene name HGF Definition (RefSeq) hepatocyte growth factor   KO K05460   hepatocyte growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr05144   Malaria umr05200   Pathways in cancer umr05205   Proteoglycans in cancer umr05211   Renal cell carcinoma umr05218   Melanoma umr05223   Non-small cell lung cancer umr05225   Hepatocellular carcinoma umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103658669 (HGF)    04014 Ras signaling pathway     103658669 (HGF)    04015 Rap1 signaling pathway     103658669 (HGF)    04020 Calcium signaling pathway     103658669 (HGF)    04151 PI3K-Akt signaling pathway     103658669 (HGF)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103658669 (HGF)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103658669 (HGF)    05205 Proteoglycans in cancer     103658669 (HGF)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     103658669 (HGF)    05226 Gastric cancer     103658669 (HGF)    05218 Melanoma     103658669 (HGF)    05211 Renal cell carcinoma     103658669 (HGF)    05223 Non-small cell lung cancer     103658669 (HGF)   09174 Infectious disease: parasitic    05144 Malaria     103658669 (HGF)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103658669 (HGF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103658669 (HGF)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103658669 (HGF) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103658669 (HGF) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103658669 (HGF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Kringle Trypsin PAN_1 DUF1986 DUF316 CWC25 Motif Other DBs NCBI-GeneID:  103658669 NCBI-ProteinID:  XP_008684405 UniProt:  A0A384BP91 LinkDB All DBs Position Un AA seq 730 aa AA seqDB search MWGTKLLPVLLLQHVLLHLLLLPIAIPYAEGQKKRRNTLHEFKKSAKTTLIKEDPLLKIK TKKMNTADQCANRCIRNKGLPFTCKAFVFDKARKRCLWFPFNSMTSGVKKDFGHEFDLYE NKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRNP RGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKICQRWDHQTP HRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSTMNDTNVPV ETTECIHGQGEGYRGTINTIWNGIPCQRWDSQYPHQHDITPENFKCKDLRENYCRNPDGA ESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWEKNME DLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPTIVNL DHPVISCAKTKQLRVVNGIPTRTNVGWMVSLKYRNKHICGGSLIKESWILTARQCFPSRN KDLKDYEAWLGIHDVHGKGDEKRKQVLNVSQLVYGPEGSDLVLLKLARPAVLDDFVSTID LPNYGCTIPEKTTCSVYGWGYTGSINSDGLLRVAHLYIMGNEKCSQYHQGKVTLNESEIC AGAENIVSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHK IILTYKIPQS NT seq 2193 nt NT seq  +upstreamnt  +downstreamnt atgtgggggaccaaacttctgccagtcctgctgctgcagcatgtcctcctacatctgctt ctgcttcccatcgccatcccctatgcagaaggacagaagaaaagaagaaacacacttcat gaattcaaaaagtcagcaaagactactctaattaaagaagacccattactgaagataaaa acaaaaaaaatgaacactgcagaccaatgtgccaatagatgtattaggaataaaggactt ccattcacttgcaaggcctttgtttttgataaagcaaggaaaagatgcctctggttccct ttcaatagcatgacaagtggcgtgaaaaaagactttggtcatgaattcgacctctatgaa aacaaagactacattagaaactgcatcattggtaaaggaggtagctacaagggaacggta tctatcactaagagtggcatcaaatgccagccctggaattccatgatcccacatgaacac agctttttgccttcgagctatcggggtaaagacctacaggaaaactactgtcgaaatcct cgaggggaagaagggggaccttggtgtttcacaagcaatccagaggtacgctacgaagtc tgtgacattcctcagtgttccgaagttgaatgcatgacctgcaatggggaaagttatcga ggtcccatggatcatacagaatcaggcaagatttgtcagcgctgggatcatcagacacca caccggcacaaattcttgccagaaagatatcccgacaagggctttgatgataattattgc cgcaatcctgatggcaaaccgaggccatggtgctatactcttgaccctgacaccccctgg gagtactgtgcaattaaaatgtgcgctcacagtactatgaatgacacaaatgtccctgtg gaaacaactgaatgcattcatggtcaaggagaaggttaccggggcaccatcaatactatt tggaatggaattccatgtcagcgttgggattcccagtatcctcaccagcatgacataact cctgaaaatttcaagtgcaaggacctaagagaaaattattgccgaaatccagatggggct gagtcaccctggtgttttaccactgatccaaacatccgagttggctactgctcccaaatt ccaaaatgtgatgtgtcaagtggacaagattgttatcgtgggaatggcaaaaattatatg ggcaatttatccaaaactcgatctggactaacatgttcaatgtgggagaagaacatggaa gacttacacaggcatatcttctgggaaccagatgctagtaagctgaataagaattactgc cggaatcctgatgatgatgcccatggtccctggtgttacacaggaaatcctctcattcca tgggattattgtcctatttctcgttgtgaaggtgataccacacctacaatagtcaattta gaccatcctgtaatatcttgtgccaaaacgaaacaattaagagttgtaaatggaattcca acgcgaactaatgtaggatggatggttagtttgaaatacagaaataaacatatctgtgga ggatcattgataaaggaaagttggattcttaccgcaagacaatgtttcccttctcgaaac aaagacttgaaagattatgaagcttggcttgggattcatgatgtccacggaaaaggagac gagaaacgcaaacaagttctaaatgtttcccagctggtatatggacctgaaggatcagat ctggtattactgaagcttgctaggcccgctgtcctggatgattttgttagtacaattgat ttacctaattatggatgcaccattcctgaaaaaaccacttgcagtgtttatggctggggt tatactggatccatcaactctgatggtctattacgagtagcacatctctatattatggga aatgagaaatgcagccaataccatcaagggaaggtgactctgaatgagtctgaaatatgt gctggagctgaaaatattgtatcaggaccatgtgagggagattatggtggcccacttgtt tgtgaacaacataaaatgagaatggttcttggtgtcattgttcctggtcgtggatgtgcc ataccaaatcgtcctggcatttttgtccgagtagcatattacgcaaaatggatacacaaa attatattaacgtataagataccacagtcatag

Ursus maritimus (polar bear): 103658995 Help Entry 103658995         CDS       T03271                                  Gene name FGF8 Definition (RefSeq) fibroblast growth factor 8   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103658995 (FGF8)    04014 Ras signaling pathway     103658995 (FGF8)    04015 Rap1 signaling pathway     103658995 (FGF8)    04020 Calcium signaling pathway     103658995 (FGF8)    04151 PI3K-Akt signaling pathway     103658995 (FGF8)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103658995 (FGF8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103658995 (FGF8)   09162 Cancer: specific types    05226 Gastric cancer     103658995 (FGF8)    05218 Melanoma     103658995 (FGF8)    05224 Breast cancer     103658995 (FGF8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103658995 (FGF8)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103658995 (FGF8) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103658995 (FGF8) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103658995 (FGF8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103658995 NCBI-ProteinID:  XP_008684733 UniProt:  A0A384BQ59 LinkDB All DBs Position Un AA seq 363 aa AA seqDB search MGATRAPGQSSIIMACCVFFNFLKVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSR TSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAK CPGLVLQSSYWANPGTSSLWASVPRHCFGVGVTPRLPNHVGLSELKGNAPVPSHPMLGHC MPSHLIVLPSLSLGFLDTLPSLPPVTLSNEEETHKTLTAANTPCRIRLISGVIGEAGGRQ GEVPVFRLHPLHWGSHTNGVGSIWVSTMYSTGGDRERGRREDESRGAVWTPQGNLSFLNL NFLIEKVEKEMEGPSPSGFSGAFRQKTLARALRGGGVGWAPGLPSRAAPVAPAPREGASR SSS NT seq 1092 nt NT seq  +upstreamnt  +downstreamnt atgggggccactcgggcccctgggcagagtagcattataatggcgtgttgtgtatttttc aatttcctaaaggtaactgttcagtcctcacctaattttacacagcatgtgagggagcag agcctggtgacggatcagctcagccgccgcctcatccggacctaccagctctacagccgc accagcgggaagcacgtgcaggtcctggccaacaagcgcatcaacgccatggcagaagac ggggaccccttcgcaaagctcattgtggagacagatacctttgggagccgggttcgagtc cgcggagctgagactggcctctacatctgcatgaataagaaggggaagctgatcgccaag tgccctgggctggtcctacagtccagctactgggccaatccaggaacctcttccctctgg gcctctgttcctcggcactgctttggagtgggggtcaccccaaggctgcctaaccacgtg ggcctctcagagctgaagggaaatgcccctgtcccatcgcaccctatgctgggccattgt atgccctcccacctcatcgtcctgcccagtctctccctgggctttctggacaccctcccc tccctgccccctgtaaccctcagtaatgaggaggagactcataaaacattgaccgcggct aatacgccgtgtaggatccgccttatctcaggtgtgataggagaggctgggggcagacaa ggcgaggtcccggtcttcaggctgcaccccttgcactggggttcacatactaacggcgtg ggcagcatctgggttagcaccatgtactccactgggggggatcgtgaaaggggtcgcaga gaagatgagtcaagaggagcagtgtggactcctcagggaaacttatctttcctgaacctt aatttcctcatcgagaaggtggagaaggagatggagggtccgagcccttcggggttctcg ggggcattccggcagaagacgctggcaagggccctccggggaggaggggtcgggtgggct ccaggcctgccgtccagggccgcccccgtggccccagccccccgggaaggtgcctccagg agcagcagctga

Ursus maritimus (polar bear): 103661742 Help Entry 103661742         CDS       T03271                                  Gene name EGF Definition (RefSeq) epidermal growth factor   KO K04357   epidermal growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04012   ErbB signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04066   HIF-1 signaling pathway umr04068   FoxO signaling pathway umr04072   Phospholipase D signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr04540   Gap junction umr04630   JAK-STAT signaling pathway umr04810   Regulation of actin cytoskeleton umr05160   Hepatitis C umr05165   Human papillomavirus infection umr05200   Pathways in cancer umr05210   Colorectal cancer umr05212   Pancreatic cancer umr05213   Endometrial cancer umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05219   Bladder cancer umr05223   Non-small cell lung cancer umr05224   Breast cancer umr05226   Gastric cancer umr05231   Choline metabolism in cancer umr05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103661742 (EGF)    04012 ErbB signaling pathway     103661742 (EGF)    04014 Ras signaling pathway     103661742 (EGF)    04015 Rap1 signaling pathway     103661742 (EGF)    04630 JAK-STAT signaling pathway     103661742 (EGF)    04066 HIF-1 signaling pathway     103661742 (EGF)    04068 FoxO signaling pathway     103661742 (EGF)    04020 Calcium signaling pathway     103661742 (EGF)    04072 Phospholipase D signaling pathway     103661742 (EGF)    04151 PI3K-Akt signaling pathway     103661742 (EGF)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103661742 (EGF)    04540 Gap junction     103661742 (EGF)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103661742 (EGF)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103661742 (EGF)    05231 Choline metabolism in cancer     103661742 (EGF)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     103661742 (EGF)   09162 Cancer: specific types    05210 Colorectal cancer     103661742 (EGF)    05212 Pancreatic cancer     103661742 (EGF)    05226 Gastric cancer     103661742 (EGF)    05214 Glioma     103661742 (EGF)    05218 Melanoma     103661742 (EGF)    05219 Bladder cancer     103661742 (EGF)    05215 Prostate cancer     103661742 (EGF)    05213 Endometrial cancer     103661742 (EGF)    05224 Breast cancer     103661742 (EGF)    05223 Non-small cell lung cancer     103661742 (EGF)   09172 Infectious disease: viral    05160 Hepatitis C     103661742 (EGF)    05165 Human papillomavirus infection     103661742 (EGF)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103661742 (EGF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103661742 (EGF) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103661742 (EGF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b FXa_inhibition cEGF EGF_CA EGF DUF5050 EGF_3 Plasmod_Pvs28 Tme5_EGF_like Motif Other DBs NCBI-GeneID:  103661742 NCBI-ProteinID:  XP_008687650 UniProt:  A0A384BZR2 LinkDB All DBs Position Un AA seq 1155 aa AA seqDB search MLLFLIILLPVVFQCSFASLSVLQRWNCPGGSPSGRGNSTCVGPAPFLIFSHGSSIFRID LGGTNHEQLVADAGVSVIMDFHYNEGRIYWVDLERKLLQRVFLNGTRQESICNIEKNVSG MAVNWINEELIWSNQQEGIITVTDMKGDNSRVLLSALNYPANVAIDPVERFIFWSSEVAG SLHRADLNGVEEKILLKTSARITAVSLDVLDKRLFWIQYNRDESNSYICSCNYDGGSVHF SKHLTQHNLFAVSLFGDRIFYSAWKKKTIWIANKHTGKDMVKINLDPSFVPPGGIKVVHP LLQPKAERGTQAPDQRLCKWRKGNCRGGMCGQDSKSHLCTCAEGYTLSQDGKYCEDVNEC AFWNHGCTLGCENIPGSYYCTCPVGFILLPDGKRCHQLISCPSNTSKCSHDCVLTSDGPV CFCPEGSVLETDGKTCSGCSSPDNGGCSQLCLPLSPVSWECGCFPGYDLQLDKKSCVASG PQPFLLFANSQDIRRMHFDGTDYGTLLSQQMGMVFALDHDPVENKIYFAHTALKWIERAN MDGSQRERLIEEAVDVPEGLAIDWIDRKFYWTDRGKSFIEGSDLSGKHREIIIKEDISQP RGIAVHPMAKRLFWTDMGINPRIESSSLQGIGRLVIASSNLVWPSGITIDYLTDKLYWCD AKLSVIEMANLDGSKRQRLAQNDVGHPFAVAVFEDHVWFSDWTMPSVIRVNKRTGKNRVR LRGSMLKPSSLVVVHPLAKPGAQPCLHQNGGCEHICKERFGTAQCLCREGFVKAPDGKMC LALNGHQIPAGNEADQVTPLDVLSRNRGFEDNITESQHLLVAEIMVSDADDCGPVGCSTR AQCVSEGDNATCQCLKGFTGDGKLCFDIDECETGTTVCPPTSSKCVNTEGGYVCRCSEGY RGDGIHCLDINECQLGMHTCGENATCTNTEGNYTCMCAGSLSEPGRICADSTPPSHLMED GRHSVRNSYRECPSSYEGYCLYNGVCMYIEAVDRYACKTKKLPSKNLKNPYEESSREVSS SRPTDNEARMASCPQPWFVVIKEHQNLRNGSQPMAVKDGEVADVSQSSSLEPGSVQQTSW RNEPQVSMGAEQGCHPPPSSDRGSGPQAMEQSFPLPSYGARPIALGIEKPHSLLSGNPYX QQRAPDPPHQKKRTW NT seq 3468 nt NT seq  +upstreamnt  +downstreamnt atgctgctcttcctcatcattctgttgccggtagtttttcagtgtagttttgctagtctc tcagtcctgcaacgctggaactgtcctggaggctctccctcaggaagggggaattctact tgtgtgggtcctgcacccttcttgattttctcccatggaagcagtatctttaggattgac ctgggaggaactaatcatgagcaattggtggcagatgctggcgtatcagtgatcatggat tttcattacaatgagggaagaatctattgggtagatttagagagaaaacttttgcaaaga gtttttctgaatgggacaaggcaagagagcatatgcaatatagagaaaaatgtttcagga atggcagtaaattggataaatgaagaacttatttggtcaaatcaacaggaaggaatcatt acagtaacagatatgaaaggagacaattcccgagttctcttaagcgccttaaattatcct gcaaatgtagcaattgatccagtagaaaggtttatattttggtcgtcagaggtggctggc agccttcacagagccgatctcaacggtgtggaagagaagattctgttaaagacgtcagca agaataacagctgtgtcattggatgtgcttgataagcggcttttttggattcagtacaac agagatgaaagcaattcttatatttgttcctgtaattatgatggaggttctgtccatttt agcaaacatctcacacagcacaatttgtttgcagtgtccctttttggtgatcggatcttc tattcagcatggaaaaagaagacaatttggatagctaacaaacacaccgggaaggatatg gttaaaattaacctcgacccatcgtttgtaccacctggcggaatcaaagtagtgcatccg ctcttgcagcccaaggcagagaggggtactcaggcacctgatcagagactctgcaaatgg aggaaaggtaactgcagaggcggcatgtgtggtcaagactcgaagtcccatctgtgcaca tgtgcagaaggatatactttaagccaagatggaaagtactgtgaagatgtcaatgaatgt gccttttggaaccatggctgtactcttgggtgtgaaaacatccctggatcttattattgc acatgtcctgtaggatttattctgcttcctgatgggaaacggtgtcatcaattaatttcc tgtccaagcaatacttctaaatgtagccatgactgtgttctgacatcagatggtcctgta tgtttctgtcctgaaggctcagtgcttgagacagatggaaaaacatgtagtggctgttcc tcacctgataatggtggatgcagccagctctgcctccctctcagccctgtctcctgggag tgtggttgctttcctgggtatgacctccaactggacaagaaaagctgtgtggcgtcagga ccacagccatttttgctgtttgctaattctcaagatattcgacgcatgcattttgatgga acagattatggaaccctgctcagccagcaaatgggaatggtttttgcccttgatcatgac cctgtggaaaataagatatactttgcccatacagccctgaagtggatagagagagctaat atggatggttcccagcgagaaaggcttattgaggaagcagtagatgtgcctgaaggtctt gccatcgattggattgaccgtaaattctactggacagacagagggaaatctttcattgaa gggagtgatttaagtggaaaacatcgtgaaataatcatcaaggaggacatctctcagcca cgaggaattgctgtccatccaatggccaagagattattctggactgatatggggattaat ccacgaattgaaagttcttctcttcaaggcattggccgactggttatagctagttccaat ctggtctggcccagtggaataacaattgattacttaactgacaaactgtattggtgtgat gccaagctgtctgtgatcgaaatggccaatctggatggttcaaaacgccaaaggcttgcc cagaacgatgtagggcacccctttgctgtggctgtgtttgaggatcatgtgtggttctcg gattggactatgccatcggtaataagggtgaacaagaggactggcaaaaatagggtacgt ctccgaggcagcatgctgaagccttcatcactggttgtagttcatccattggcaaaacca ggagcacagccctgcttacatcaaaatggaggctgtgaacatatttgcaaagagaggttt ggaactgctcagtgtttgtgtcgcgaaggttttgtgaaagccccagatgggaaaatgtgt ctggctctgaatggccatcagataccggcaggtaatgaagcagatcaagtaacaccattg gacgtcttatccaggaacagaggatttgaagataacattacagaatctcagcatttgcta gtggctgaaatcatggtatcagatgctgatgactgcggtcctgtgggatgcagtacacga gctcagtgtgtttcagagggagacaatgccacatgtcagtgtttgaaaggatttactggg gatggaaaactatgttttgatatagatgaatgtgagacgggcaccacagtttgccctcct acctcctctaagtgtgtcaataccgaaggcggctatgtctgccggtgctcagaaggctac cgaggcgatgggattcactgtcttgatattaatgagtgccaattgggcatgcacacctgt ggggaaaatgccacctgtacaaatacggaggggaactacacctgcatgtgtgctggcagc ctgtctgaacctgggcggatatgcgctgactctactccgccttctcatctcatggaagat ggccgccattctgtgagaaatagttaccgggaatgcccctcatcctatgagggctactgc ctctataatggtgtgtgtatgtacatcgaagcagttgacagatacgcatgcaagactaag aagctgccatcaaaaaatttaaagaatccttacgaagagtcaagcagagaagttagcagt agcaggcctacagacaacgaggccaggatggcctcttgtccccagccttggtttgtggtg ataaaggaacaccaaaatctcaggaatggaagtcaacctatggctgtcaaggacggtgag gtagcagatgttagccagtcctcctctctggagccaggctcagtgcaacagacgtcatgg agaaatgaaccccaggtgtctatgggcgcagagcaaggctgccatcctccaccatccagt gatagaggctctggtccccaggcaatggagcagagctttcctctcccctcctatggggca cggcccattgctttggggatcgagaagccccattctctcctgtcaggtaacccttatngg caacaaagggccccagatccaccacaccaaaagaagcggacttggtga

Ursus maritimus (polar bear): 103661850 Help Entry 103661850         CDS       T03271                                  Gene name FGF2 Definition (RefSeq) fibroblast growth factor 2   KO K18497   fibroblast growth factor 2 Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04550   Signaling pathways regulating pluripotency of stem cells umr04810   Regulation of actin cytoskeleton umr05167   Kaposi sarcoma-associated herpesvirus infection umr05200   Pathways in cancer umr05205   Proteoglycans in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103661850 (FGF2)    04014 Ras signaling pathway     103661850 (FGF2)    04015 Rap1 signaling pathway     103661850 (FGF2)    04020 Calcium signaling pathway     103661850 (FGF2)    04151 PI3K-Akt signaling pathway     103661850 (FGF2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     103661850 (FGF2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103661850 (FGF2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103661850 (FGF2)    05205 Proteoglycans in cancer     103661850 (FGF2)   09162 Cancer: specific types    05226 Gastric cancer     103661850 (FGF2)    05218 Melanoma     103661850 (FGF2)    05224 Breast cancer     103661850 (FGF2)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     103661850 (FGF2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103661850 (FGF2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103661850 (FGF2)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103661850 (FGF2) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103661850 (FGF2) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103661850 (FGF2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Fascin IL1 Motif Other DBs NCBI-GeneID:  103661850 NCBI-ProteinID:  XP_008687743 UniProt:  A0A384BYT3 LinkDB All DBs Position Un AA seq 243 aa AA seqDB search MVLYSEHSADPLEVLEEEHGMLKQQFKTIVLNETVGFDCYHHPMAAKAPQRGGRLNVARV AQGWAGATSGELSRGRAPRAAEASAVASPLALRTSPAPGCVRAPPGTDFPPGHFKDPKRL YCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLL ASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMS AKS NT seq 732 nt NT seq  +upstreamnt  +downstreamnt atggtcctttattcagaacacagtgcagatcccttggaggttctggaggaagaacatggc atgctcaagcagcagttcaaaacaattgttttaaatgagactgtaggatttgactgctac caccatcccatggcagcaaaagctccgcagcgtggaggaagactaaatgtggctcgggtg gcgcagggttgggctggggcgacttctggggaacttagccggggtcgagcccctagagct gcggaggcctctgcggtcgcctccccgctcgccctccgcacctcccccgcccccggctgc gttcgggctccccccgggaccgatttcccgcccggccacttcaaggaccccaaacggctg tactgcaaaaacgggggcttcttcctgcgcatccaccccgacggccgagtggacggggtc cgggagaagagcgaccctcatatcaaactgcaacttcaagcggaagagagaggggttgtg tccatcaaaggagtatgtgcaaatcgctatcttgccatgaaggaagatggaagattactg gcttctaaatgtgttaccgatgagtgtttcttttttgagcgactggaatctaataactac aatacttaccggtcaaggaaatactccagttggtatgtggcactgaaacggactgggcag tataaacttggacccaaaacaggacctgggcagaaagctatactttttcttccaatgtct gctaagagctga

Ursus maritimus (polar bear): 103662543 Help Entry 103662543         CDS       T03271                                  Gene name PDGFD Definition (RefSeq) platelet derived growth factor D   KO K05450   platelet derived growth factor C/D Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04072   Phospholipase D signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr04540   Gap junction umr04810   Regulation of actin cytoskeleton umr05215   Prostate cancer umr05218   Melanoma umr05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103662543 (PDGFD)    04014 Ras signaling pathway     103662543 (PDGFD)    04015 Rap1 signaling pathway     103662543 (PDGFD)    04020 Calcium signaling pathway     103662543 (PDGFD)    04072 Phospholipase D signaling pathway     103662543 (PDGFD)    04151 PI3K-Akt signaling pathway     103662543 (PDGFD)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103662543 (PDGFD)    04540 Gap junction     103662543 (PDGFD)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103662543 (PDGFD)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     103662543 (PDGFD)   09162 Cancer: specific types    05218 Melanoma     103662543 (PDGFD)    05215 Prostate cancer     103662543 (PDGFD)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103662543 (PDGFD)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103662543 (PDGFD) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103662543 (PDGFD) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  CUB PDGF Motif Other DBs NCBI-GeneID:  103662543 NCBI-ProteinID:  XP_008688444 UniProt:  A0A384C1Y3 LinkDB All DBs Position Un AA seq 365 aa AA seqDB search LVYTLVCANFCSYRDTSAAPQSAAIKALRNANLRRDESNHLTDLYRRDETIQVTGSGHVQ SPRFPNSYPRNLLLTWRLRSRENTRIQLAFDHRFGLEEAENDICRYDFVEVEDVSETSTI IRGRWCGHKEVPPRITSRTNQIKITFKSDDYFVAKPGFKIYYSFVEDFQPAAASETNWES VTSSVSGVSYHSPSVTDPTLTADALDKTVAEFDTVEDLLKHFNPESWQEDLENLYLETPH YRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNYSVNLREELKLTHVVFFPRCLLVQRCGGN CGCGTINWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGRAKHMALVDIQLDHHERCDCICS SRPPR NT seq 1098 nt NT seq  +upstreamnt  +downstreamnt ctcgtctacacgctcgtctgcgccaacttttgcagctatcgggacacttctgctgcgccg cagagcgcagccatcaaagctttgcgcaacgccaacctcaggcgagatgagagcaatcac ctcacagacttgtaccgaagagacgagaccatccaggtgacaggcagcggccacgtgcag agccctcgcttccccaacagctaccccaggaatctgctcctcacatggcggctccgttcc cgggagaacacaaggatacagctcgccttcgaccatcggttcgggctggaggaagccgag aatgacatctgtaggtatgattttgtggaagttgaagatgtatctgaaaccagtaccata attagaggtcggtggtgtggacacaaggaagttcctccaaggatcacatcaagaacgaac caaattaaaataacattcaagtctgatgactactttgtggctaaacctggattcaagatt tattattcttttgtggaagatttccaacccgcagcagcctcagagaccaactgggagtca gtcacaagctctgtctcaggggtatcctatcactctccatcagtaacggaccccaccctc actgcggatgctctggacaaaacagtcgcagaatttgataccgtggaagatctgctcaag cacttcaatccagaatcatggcaagaagatcttgagaatctatatttggagaccccccat tatcgaggcaggtcctaccatgaccggaagtcaaaagtcgacctggacaggctcaatgat gacgtcaagcgctacagttgcactcccaggaattactccgtcaacttaagagaggagctg aagctcacgcacgtggtcttctttccccgttgcctcctcgtgcagcgctgtgggggcaac tgtggctgtgggaccatcaactggaaatcctgcacctgcagctccgggaaaactgtgaaa aagtatcatgaggtattaaagtttgagcctggccatttcaagaggaggggcagagcgaag cacatggctctcgttgacatccagttggaccaccacgagcggtgtgactgcatctgcagc tcgagaccgcctcgataa

Ursus maritimus (polar bear): 103663709 Help Entry 103663709         CDS       T03271                                  Gene name FGF1 Definition (RefSeq) fibroblast growth factor 1   KO K18496   fibroblast growth factor 1 Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04390   Hippo signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103663709 (FGF1)    04014 Ras signaling pathway     103663709 (FGF1)    04015 Rap1 signaling pathway     103663709 (FGF1)    04390 Hippo signaling pathway     103663709 (FGF1)    04020 Calcium signaling pathway     103663709 (FGF1)    04151 PI3K-Akt signaling pathway     103663709 (FGF1)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103663709 (FGF1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103663709 (FGF1)   09162 Cancer: specific types    05226 Gastric cancer     103663709 (FGF1)    05218 Melanoma     103663709 (FGF1)    05224 Breast cancer     103663709 (FGF1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103663709 (FGF1)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103663709 (FGF1) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103663709 (FGF1) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103663709 (FGF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Fascin Motif Other DBs NCBI-GeneID:  103663709 NCBI-ProteinID:  XP_008689675 UniProt:  A0A384C499 LinkDB All DBs Position Un AA seq 155 aa AA seqDB search MAEGEITTFTALTEKFNLPAGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQ LSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTANEECLFLERLEENHYNTYTSKKHAEK NWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD NT seq 468 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggggagatcacaaccttcaccgccctgacggagaagtttaatctgcctgcg gggaattacaagaagcccaaactcctctactgtagcaacgggggccacttcctgaggatc cttccagatggcacagtggacgggacgagggacaggagcgaccagcacattcaactgcag ctcagtgcggaaagcgtaggggaggtgtacataaagagcaccgagaccggccagtacttg gccatggacaccgatgggcttttgtacggctcacagacagcaaatgaggaatgtttgttc ctggaaaggctggaggaaaaccattacaacacctacacatccaagaagcacgcggagaag aattggtttgttggtctcaagaagaacggaagctgcaaacgtggtcctcggactcactat ggccagaaagcaattctgtttctccccctgccagtctcctctgattaa

Ursus maritimus (polar bear): 103664292 Help Entry 103664292         CDS       T03271                                  Gene name FGF9 Definition (RefSeq) fibroblast growth factor 9   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103664292 (FGF9)    04014 Ras signaling pathway     103664292 (FGF9)    04015 Rap1 signaling pathway     103664292 (FGF9)    04020 Calcium signaling pathway     103664292 (FGF9)    04151 PI3K-Akt signaling pathway     103664292 (FGF9)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103664292 (FGF9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103664292 (FGF9)   09162 Cancer: specific types    05226 Gastric cancer     103664292 (FGF9)    05218 Melanoma     103664292 (FGF9)    05224 Breast cancer     103664292 (FGF9)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103664292 (FGF9)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103664292 (FGF9) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103664292 (FGF9) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103664292 (FGF9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103664292 NCBI-ProteinID:  XP_008690358 UniProt:  A0A384C698 LinkDB All DBs Position Un AA seq 208 aa AA seqDB search MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGI LRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNE KGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKR HQKFTHFLPRPVDPDKVPELYKDILSQS NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atggctcccttaggtgaagttgggaactatttcggtgtgcaggatgcggtaccgtttggg aatgtgcccgtgttgccggtggacagtccggttttgttaagtgaccacctgggtcagtcc gaagcaggggggcttcccaggggacccgcagtcacggacttggatcatttaaaggggatt ctcaggcggaggcagctatactgcaggactggatttcacttagaaatcttccccaatggt actatccagggaaccaggaaagaccacagccgatttggcattctggaatttatcagtata gcagtgggcctggtcagcattcgaggcgtggacagtggactctacctcgggatgaatgag aagggggagctgtatggatcagaaaaactaacccaagagtgtgtattcagagaacagttt gaagaaaactggtataacacatactcctcgaatctatataaacacgtggacactggaagg cgatactatgttgcattaaataaagacgggaccccaagagaaggaacgaggactaaacgg caccagaaattcacacattttttacctagaccagtggaccctgacaaagtacctgaacta tataaggatattctaagccaaagttga

Ursus maritimus (polar bear): 103664645 Help Entry 103664645         CDS       T03271                                  Gene name FGF10 Definition (RefSeq) fibroblast growth factor 10   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103664645 (FGF10)    04014 Ras signaling pathway     103664645 (FGF10)    04015 Rap1 signaling pathway     103664645 (FGF10)    04020 Calcium signaling pathway     103664645 (FGF10)    04151 PI3K-Akt signaling pathway     103664645 (FGF10)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103664645 (FGF10)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103664645 (FGF10)   09162 Cancer: specific types    05226 Gastric cancer     103664645 (FGF10)    05218 Melanoma     103664645 (FGF10)    05224 Breast cancer     103664645 (FGF10)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103664645 (FGF10)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103664645 (FGF10) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103664645 (FGF10) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103664645 (FGF10) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Fascin SR-25 Motif Other DBs NCBI-GeneID:  103664645 NCBI-ProteinID:  XP_008690782 UniProt:  A0A384C7J2 LinkDB All DBs Position Un AA seq 214 aa AA seqDB search MWKWILTHCASAFPHLPGCCCCFLLLFLVSSIPVTCQALGQDMVSPEATNSSSSSSSSSS SSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEIT SVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGR QMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS NT seq 645 nt NT seq  +upstreamnt  +downstreamnt atgtggaaatggatactgacacattgtgcctcagcctttccccacctgcctggctgctgc tgctgcttcttgttgctgttcttggtgtcttccatccctgtcacctgccaagcccttggt caggacatggtgtcaccagaggccaccaactcctcttcttcctcctcctcctcgtcctct tcctccttctcctctccttccagtgcggggaggcatgtgcggagctacaatcacctccaa ggagatgtccgctggagaaagctattctcttttaccaagtactttctcaagattgagaag aacgggaaggtcagcggtaccaagaaggagaactgcccgtacagtatcctagagataact tcagtggaaatcggagttgttgccgtcaaagccattaacagcaactattatttagccatg aacaagaaggggaaactctatggctcaaaagaatttaacaatgactgtaagctgaaggag aggatagaggaaaatggatataacacatatgcatcctttaactggcagcacaatgggagg caaatgtacgtggcattgaatggaaaaggagctcccaggagaggacagaaaacacgaagg aaaaacacctcagcgcattttcttccaatggtggtacactcgtag

Ursus maritimus (polar bear): 103664781 Help Entry 103664781         CDS       T03271                                  Gene name FGF18 Definition (RefSeq) fibroblast growth factor 18   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103664781 (FGF18)    04014 Ras signaling pathway     103664781 (FGF18)    04015 Rap1 signaling pathway     103664781 (FGF18)    04020 Calcium signaling pathway     103664781 (FGF18)    04151 PI3K-Akt signaling pathway     103664781 (FGF18)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103664781 (FGF18)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103664781 (FGF18)   09162 Cancer: specific types    05226 Gastric cancer     103664781 (FGF18)    05218 Melanoma     103664781 (FGF18)    05224 Breast cancer     103664781 (FGF18)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103664781 (FGF18)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103664781 (FGF18) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103664781 (FGF18) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103664781 (FGF18) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103664781 NCBI-ProteinID:  XP_008690930 UniProt:  A0A384C962 LinkDB All DBs Position Un AA seq 211 aa AA seqDB search MYMAPLTTSPSLSRRCLHFLLLCFQVQVLAAEENVDFRIHVENQTRARDDVSRKQLRLGP LYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKL VGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMK RYPKGQAELQKPFKYTTVTKRSRRIRPTHPG NT seq 636 nt NT seq  +upstreamnt  +downstreamnt atgtacatggccccactgaccacctctccatctctctctcgcaggtgtttacacttcctg ctgctgtgcttccaggtacaggtgctggcggccgaggagaacgtggacttccgcatccac gtggagaaccagacgcgggctcgggacgatgtgagccgtaagcagctgcggctgggccca ctctacagccggaccagcgggaagcacatccaggtgctgggccgcaggatcagcgcccgc ggcgaggacggggacaagtatgcccagctcctagtggagacagacaccttcggtagtcaa gtccggatcaagggcaaggagacggaattctacctgtgtatgaaccggaaaggcaagctc gtggggaagcccgatggcaccagcaaggagtgtgtattcattgagaaggtcctggagaac aactacacagccctaatgtccgccaagtactctggctggtacgtgggcttcaccaagaag gggcggccacggaagggtcccaagacgcgagagaaccagcaggacgtgcacttcatgaag cgctaccccaagggacaggcagagctgcagaagcccttcaagtacaccacggtgaccaag aggtcccggcggatccgccccacgcaccccggctag

Ursus maritimus (polar bear): 103665349 Help Entry 103665349         CDS       T03271                                  Gene name FGF5 Definition (RefSeq) fibroblast growth factor 5   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103665349 (FGF5)    04014 Ras signaling pathway     103665349 (FGF5)    04015 Rap1 signaling pathway     103665349 (FGF5)    04020 Calcium signaling pathway     103665349 (FGF5)    04151 PI3K-Akt signaling pathway     103665349 (FGF5)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103665349 (FGF5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103665349 (FGF5)   09162 Cancer: specific types    05226 Gastric cancer     103665349 (FGF5)    05218 Melanoma     103665349 (FGF5)    05224 Breast cancer     103665349 (FGF5)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103665349 (FGF5)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103665349 (FGF5) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103665349 (FGF5) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103665349 (FGF5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103665349 NCBI-ProteinID:  XP_008691494 UniProt:  A0A384CAK8 LinkDB All DBs Position Un AA seq 284 aa AA seqDB search MSLSFLLLLFLSHLILSAWAHGEKHLAPKGQPGPAATGRNPGGASSSRSSSGTTSSSSSS DSSSPGASLGSQGSGLEQTSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANML SILEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASENGFLPNRSRSQVKAKFTDDCKFRE RFQENSYNTYASAIHRTEPAGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQVEQ PELSFTVTVPEKKKPPSPVKPKVPVSAPRKSPNTVKYRLKFRFG NT seq 855 nt NT seq  +upstreamnt  +downstreamnt atgagcttgtccttcctcctcctcctcttcctcagccacctaatcctcagcgcctgggct cacggggagaagcacctcgcccccaaagggcaacccggacccgctgccaccggtcggaac ccgggaggcgccagcagcagccggagcagcagtggcacgacgtcttcctcttcttcctcc gactcctcctcccccggggcttctctgggcagccaagggagcggcttggagcagaccagt ttccagtggagcccctcggggcgccggaccggcagcctctactgcagagtgggcatcggt ttccatctgcagatctacccggatggcaaagtcaatggctcccatgaagccaatatgtta agtattttggaaatatttgctgtgtctcaggggattgtaggaatacgaggagttttcagc aacaaatttttagcgatgtcaaaaaaaggaaaactccatgcaagtgaaaatggatttttg ccaaacaggagtagaagtcaggtcaaggccaaatttacagatgattgcaagttcagggag cgatttcaagaaaacagctataatacctatgcctcagcaatacacagaactgagccagcg ggccgggagtggtacgtggccctcaataagagagggaaggccaagcggggctgcagcccc cgggtcaaaccccagcacatctccacccactttctgccaagattcaagcaggtagagcag ccagaactttctttcacagttactgttcctgagaagaaaaagccacccagtccagtcaag ccaaaggttcccgtgtccgcccctcggaagagtcccaacaccgtgaaatacagactcaag tttcgctttggataa

Ursus maritimus (polar bear): 103670054 Help Entry 103670054         CDS       T03271                                  Gene name PDGFA Definition (RefSeq) platelet derived growth factor subunit A   KO K04359   platelet-derived growth factor subunit A Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04072   Phospholipase D signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr04540   Gap junction umr04630   JAK-STAT signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05206   MicroRNAs in cancer umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05231   Choline metabolism in cancer umr05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103670054 (PDGFA)    04014 Ras signaling pathway     103670054 (PDGFA)    04015 Rap1 signaling pathway     103670054 (PDGFA)    04630 JAK-STAT signaling pathway     103670054 (PDGFA)    04020 Calcium signaling pathway     103670054 (PDGFA)    04072 Phospholipase D signaling pathway     103670054 (PDGFA)    04151 PI3K-Akt signaling pathway     103670054 (PDGFA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103670054 (PDGFA)    04540 Gap junction     103670054 (PDGFA)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103670054 (PDGFA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103670054 (PDGFA)    05202 Transcriptional misregulation in cancer     103670054 (PDGFA)    05206 MicroRNAs in cancer     103670054 (PDGFA)    05231 Choline metabolism in cancer     103670054 (PDGFA)   09162 Cancer: specific types    05214 Glioma     103670054 (PDGFA)    05218 Melanoma     103670054 (PDGFA)    05215 Prostate cancer     103670054 (PDGFA)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     103670054 (PDGFA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103670054 (PDGFA)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103670054 (PDGFA)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103670054 (PDGFA) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103670054 (PDGFA) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103670054 (PDGFA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PDGF PDGF_N Motif Other DBs NCBI-GeneID:  103670054 NCBI-ProteinID:  XP_008696669 UniProt:  A0A384CQA9 LinkDB All DBs Position Un AA seq 241 aa AA seqDB search MGSSSGAYAAGGPGILHTPVCEPRDEYHRSNSASARRGAPETPEIARKHRLRGRPDIPAS RQPSKAQQGCHAGGDPRGGFPEVGGRFLAVGSLSSSAHVGVAGLSGDPVCLGEAGRTHRW TGPRTPHRCGPAGHRFLLLPVGAEDALEASLRAHGGHASKRAPEKRPMPIRRKRSIEEAI PAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCAGCCNTSSVKCQPSRVHHPHTRK A NT seq 726 nt NT seq  +upstreamnt  +downstreamnt atgggctccagttctggtgcctatgctgctgggggacccggcatccttcacactcctgtc tgtgagcctcgggacgagtaccaccggagtaattccgcttctgcacgtcggggcgcgccg gagacgcccgagatagcccggaagcaccggctccgggggcgaccggacatcccggccagt cgccagcctagcaaagcacagcaggggtgccacgctgggggggacccccgtggaggcttc cccgaggttggcgggagatttttggcagttgggagtctttcatcctctgcccacgtggga gtggcgggcctctcaggggaccctgtctgtctgggggaggcaggtaggacgcaccgctgg acaggccccaggacgccacacagatgcgggccagctggtcaccgtttcctcctcctgcct gtaggggccgaggatgctttggaagcgagtctgagagcccacgggggccatgccagcaag cgtgcacccgagaagaggcccatgcccatccgaaggaaaagaagcatcgaggaagccatc ccggcggtctgcaagaccaggacggtcatttatgagatacctcggagccaggtcgacccc acgtctgccaacttcctgatctggcccccgtgcgtggaggtgaagcgctgtgccgggtgc tgtaacaccagcagcgtcaagtgccagccctcccgcgtccaccacccgcacaccaggaag gcgtag

Ursus maritimus (polar bear): 103671137 Help Entry 103671137         CDS       T03271                                  Gene name FGF3 Definition (RefSeq) fibroblast growth factor 3   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103671137 (FGF3)    04014 Ras signaling pathway     103671137 (FGF3)    04015 Rap1 signaling pathway     103671137 (FGF3)    04020 Calcium signaling pathway     103671137 (FGF3)    04151 PI3K-Akt signaling pathway     103671137 (FGF3)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103671137 (FGF3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103671137 (FGF3)   09162 Cancer: specific types    05226 Gastric cancer     103671137 (FGF3)    05218 Melanoma     103671137 (FGF3)    05224 Breast cancer     103671137 (FGF3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103671137 (FGF3)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103671137 (FGF3) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103671137 (FGF3) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103671137 (FGF3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103671137 NCBI-ProteinID:  XP_008697933 UniProt:  A0A384CT25 LinkDB All DBs Position Un AA seq 224 aa AA seqDB search MSAFPVLEHSGARTGAKHDTPASAGDNLTPTPTGLQTELEKVRGLVGGLTSGSWSSWALR KEVVGSAGPMPVLPATLALEAEDLLGCHAAVDRLVAKAEEGLILPELRLGILEMTAVEVG IVAIKGLFSGRYLAMNKRGRLYASESYNAECEFVERIHELGYNTYASRLYRTAPSGPGAQ RQPSAERLWYVSVNGKGRPRRGFKTRRTQKVALFGNRVIANVIK NT seq 675 nt NT seq  +upstreamnt  +downstreamnt atgtcagccttccccgttttggagcactccggggccaggacgggtgccaagcatgacacg ccagcctcggccggagacaacctcacgccgacacccaccggtttacaaactgagctggag aaggttcggggacttgtcggaggcctcacgtcaggcagctggagcagctgggccctgaga aaggaagtcgtggggtcagctggacccatgcctgtcctgcctgccacgctggccctcgaa gctgaggaccttctggggtgccacgccgccgtggacaggttggtagccaaggcagaagag ggactcatcctgccagaacttaggctcggtatcctggagatgacagcggtggaggtgggc atcgtggccatcaaggggctcttctccgggcggtacctggccatgaacaagagggggcgg ctctatgcttcggagagctacaacgccgagtgtgagttcgtggagcggatccacgagctg ggctacaacacgtacgcctcgcggctgtaccgcacagcgcccagcggcccgggggcccag cggcagcccagcgccgagagactgtggtatgtgtccgtgaacggcaagggcaggccccgc aggggcttcaagacgcgccgcactcagaaggtggccttatttggaaatagggtcattgca aatgtaatcaagtag

Ursus maritimus (polar bear): 103671138 Help Entry 103671138         CDS       T03271                                  Gene name FGF19 Definition (RefSeq) fibroblast growth factor 19   KO K22603   fibroblast growth factor 19 Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103671138 (FGF19)    04014 Ras signaling pathway     103671138 (FGF19)    04015 Rap1 signaling pathway     103671138 (FGF19)    04020 Calcium signaling pathway     103671138 (FGF19)    04151 PI3K-Akt signaling pathway     103671138 (FGF19)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103671138 (FGF19)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103671138 (FGF19)   09162 Cancer: specific types    05226 Gastric cancer     103671138 (FGF19)    05218 Melanoma     103671138 (FGF19)    05224 Breast cancer     103671138 (FGF19)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103671138 (FGF19)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103671138 (FGF19) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103671138 (FGF19) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103671138 (FGF19) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103671138 NCBI-ProteinID:  XP_008697934 UniProt:  A0A384CTX3 LinkDB All DBs Position Un AA seq 178 aa AA seqDB search GEPIRLRHLYTAGPHGLSSCFLRIRADGGVDCARGQSAHSLVEIRAVALRTVAIKGVHSV RYLCMGADGRMQGLPQYSAGDCAFEEEIRPDGYNVYRSKKHRLPVSLSSAKQRQLYKDRG FLPLSHFLPMLPGSPAEPRELQDHAESDGFSAPLETDSMDPFGIAAKMGLVKSPSFQK NT seq 537 nt NT seq  +upstreamnt  +downstreamnt ggtgagcccatccgcctacggcacctgtacaccgccggcccccacggcctctccagctgc ttcctgcgcatccgtgccgacggcggggttgactgcgcgcggggccagagcgcgcacagt ttggtggagatcagggcagtcgctctgcggaccgtggccatcaagggcgtgcacagcgtc cggtacctctgcatgggcgccgacggcaggatgcaagggctgcctcagtactccgcgggg gactgtgctttcgaggaggagatccgccccgacggctacaatgtgtaccggtccaagaag caccgtctccctgtctctctgagcagcgccaaacagaggcagctgtacaaggacagaggc tttctgcccctgtcccacttcttgcccatgctgcctgggagcccagcagagcccagggaa ctccaggaccacgcggagtcggacgggttttctgcacccctagaaacagacagcatggac ccttttgggatcgccgccaaaatgggactagtgaagagtcccagcttccagaaataa

Ursus maritimus (polar bear): 103673325 Help Entry 103673325         CDS       T03271                                  Gene name FGF17 Definition (RefSeq) fibroblast growth factor 17   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103673325 (FGF17)    04014 Ras signaling pathway     103673325 (FGF17)    04015 Rap1 signaling pathway     103673325 (FGF17)    04020 Calcium signaling pathway     103673325 (FGF17)    04151 PI3K-Akt signaling pathway     103673325 (FGF17)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103673325 (FGF17)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103673325 (FGF17)   09162 Cancer: specific types    05226 Gastric cancer     103673325 (FGF17)    05218 Melanoma     103673325 (FGF17)    05224 Breast cancer     103673325 (FGF17)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103673325 (FGF17)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103673325 (FGF17) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103673325 (FGF17) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103673325 (FGF17) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Fascin IL1 Motif Other DBs NCBI-GeneID:  103673325 NCBI-ProteinID:  XP_008700315 UniProt:  A0A384D0P6 LinkDB All DBs Position Un AA seq 216 aa AA seqDB search MGATRLLPRLALCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSR TSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKKGKLVGKP SGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ GQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQPLT NT seq 651 nt NT seq  +upstreamnt  +downstreamnt atgggagccacccgcctgctgccccgcctcgctctgtgtctgcaactactgattctctgc tgtcaaacccagggggagaatcacccgtctcctaattttaaccagtacgtgagggaccag ggcgccatgaccgaccagctgagcaggcggcagatccgcgagtaccagctctacagccgg accagcggcaagcacgtgcaggtcaccgggcgtcgcatctctgccactgcggaggacggc aacaagtttgccaaactcatagtggagacggacacctttggaagccgtgtgcgcatcaag ggtgctgagagtgagaaatacatctgtatgaacaagaagggcaagctcgttggaaagccc agcgggaagagcaaagactgcgtgttcacggagatcgtgctggagaacaactacacggcc ttccagaatgcccggcacgagggatggttcatggccttcaccaggcagggtcggccccgc caggcttctcgaagccgccagaaccaacgagaggctcacttcatcaagcgcctctaccag ggccagttgcccttccccaaccacgcagagaggcagaagcagttcgagttcgtgggctca gcccccacccgccggaccaagcgcactcggaggccacagcccctgacgtag

Ursus maritimus (polar bear): 103675745 Help Entry 103675745         CDS       T03271                                  Gene name FGF23 Definition (RefSeq) fibroblast growth factor 23   KO K22428   fibroblast growth factor 23 Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr04928   Parathyroid hormone synthesis, secretion and action umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103675745 (FGF23)    04014 Ras signaling pathway     103675745 (FGF23)    04015 Rap1 signaling pathway     103675745 (FGF23)    04020 Calcium signaling pathway     103675745 (FGF23)    04151 PI3K-Akt signaling pathway     103675745 (FGF23)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103675745 (FGF23)  09150 Organismal Systems   09152 Endocrine system    04928 Parathyroid hormone synthesis, secretion and action     103675745 (FGF23)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103675745 (FGF23)   09162 Cancer: specific types    05226 Gastric cancer     103675745 (FGF23)    05218 Melanoma     103675745 (FGF23)    05224 Breast cancer     103675745 (FGF23)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103675745 (FGF23)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103675745 (FGF23) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103675745 (FGF23) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103675745 (FGF23) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103675745 NCBI-ProteinID:  XP_008703099 UniProt:  A0A384D8I9 LinkDB All DBs Position Un AA seq 318 aa AA seqDB search MWTVEFFLFDVTRLPFKSPRGKRRESSLGSSGQIPTKKRRKRPARHSQGVREAVSGFKLQ PAIQSAAMSGTRLGLLVSVLCWVVRAYPNTSPLLGSSWGGLTHLYTASARNSYHLQIHKD GHVDGTPHQTIYSALIIRSEDAGFVVITGVMSRRYLCMDLRGNIFGSVSFFFVPGEARSS TWFRQRTLENGYDVYHSPQHRFLVSLGQAKRTFLPGTNPPPYSQFLSRRNEIPLIHFNTP RPRRHTRSAEDTERDPLNVLKPRPRMTPAPASCSQELPSAEDNSVVASDPLGVLRGNRVN AHAGGMGVDRCRPFPKFI NT seq 957 nt NT seq  +upstreamnt  +downstreamnt atgtggacagtggagtttttcctgtttgatgtcacacggctaccctttaaaagtccaagg ggaaaaaggagggaatccagcctaggatcctcaggccagatacccacaaagaagagaaga aagaggcctgcgaggcacagccagggagtcagggaggcagtgtcaggtttcaaactccag ccagccattcagagcgctgcgatgtccgggacccgccttgggctcctggtctctgtcctg tgctgggtagtcagagcgtatcccaacacctccccgctgctcggctccagctggggtggc ctgacccacctgtacacagccagcgccaggaacagctaccacctgcagatccacaaggac ggccatgtggatggcacaccccatcagaccatctacagtgccctgataatcaggtcagag gatgccggctttgtggtgataacaggtgtgatgagtaggcgatacctctgtatggacctc agaggcaacatctttggatccgtgagtttcttttttgtgccgggcgaagccaggtccagc acctggttccgacagcggacgctggaaaacggctacgacgtgtaccactccccgcagcac cgcttcctcgtcagcctgggccaggccaagaggaccttcctgccagggaccaacccgccg ccctactcccagttcctgtcccggaggaacgagatccccctcatccacttcaacaccccc aggccaaggcggcacacgcgcagcgccgaggacacggagcgcgacccactgaacgtgctg aagcccaggccccgcatgacccccgccccggcctcctgctcccaggagctccctagcgcc gaggacaacagtgtggtggccagcgacccgttaggggtactcagaggcaaccgggtgaac gcgcacgccggggggatgggcgtggacaggtgccgccccttccccaagttcatctag

Ursus maritimus (polar bear): 103675746 Help Entry 103675746         CDS       T03271                                  Gene name FGF6 Definition (RefSeq) fibroblast growth factor 6   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103675746 (FGF6)    04014 Ras signaling pathway     103675746 (FGF6)    04015 Rap1 signaling pathway     103675746 (FGF6)    04020 Calcium signaling pathway     103675746 (FGF6)    04151 PI3K-Akt signaling pathway     103675746 (FGF6)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103675746 (FGF6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103675746 (FGF6)   09162 Cancer: specific types    05226 Gastric cancer     103675746 (FGF6)    05218 Melanoma     103675746 (FGF6)    05224 Breast cancer     103675746 (FGF6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103675746 (FGF6)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103675746 (FGF6) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103675746 (FGF6) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103675746 (FGF6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103675746 NCBI-ProteinID:  XP_008703100 UniProt:  A0A384D8J1 LinkDB All DBs Position Un AA seq 208 aa AA seqDB search MALGQRLFITMSPGAGRLQGTLQALVFLGVLVGMVVPSPAGTRANSTLLDSRGWGTLLSR SRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVPPDGRISGTHEENPYSLLEI STVERGVVSLFGVKSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYRGTY IALSKYGRVKRGSKVSPIMTVTHFLPRI NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atggccctgggacagaggctgttcatcactatgtccccgggagcaggacgtcttcagggc acgctgcaggctctcgtcttcctaggcgtcctagtgggcatggtggtgccctcgcctgca ggcacccgggccaacagcacgctgctggactccaggggctggggcaccctgctatcaagg tctcgagccggactagctggagagattgctggggtgaattgggagagtggctatttggtg gggatcaagcggcagaggaggctctactgcaacgtgggcatcggctttcacctccaggtg ccccccgacggccggatcagcgggacccacgaggagaacccctacagcctgctggagatt tccacagtggagcggggtgtggtgagtctctttggagtgaaaagtgccctcttcgttgcc atgaacagtaaagggagattatatgcaacgcccagcttccaagaggaatgcaagttcaga gaaaccctcctgcccaacaattacaatgcctatgagtcagacctgtaccgagggacctac atcgcactgagcaaatacggacgggtaaagcgaggcagcaaggtgtccccaatcatgact gtcactcacttccttcccaggatataa

Ursus maritimus (polar bear): 103675826 Help Entry 103675826         CDS       T03271                                  Gene name FGF16 Definition (RefSeq) fibroblast growth factor 16   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103675826 (FGF16)    04014 Ras signaling pathway     103675826 (FGF16)    04015 Rap1 signaling pathway     103675826 (FGF16)    04020 Calcium signaling pathway     103675826 (FGF16)    04151 PI3K-Akt signaling pathway     103675826 (FGF16)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103675826 (FGF16)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103675826 (FGF16)   09162 Cancer: specific types    05226 Gastric cancer     103675826 (FGF16)    05218 Melanoma     103675826 (FGF16)    05224 Breast cancer     103675826 (FGF16)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103675826 (FGF16)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103675826 (FGF16) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103675826 (FGF16) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103675826 (FGF16) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103675826 NCBI-ProteinID:  XP_008703181 UniProt:  A0A384D894 LinkDB All DBs Position Un AA seq 184 aa AA seqDB search MRELTLEAQQQFVRAKEITEGSSRVSYRQLTASCGFKDMGAKRVQNKVSLEGNEFDINNR NGIHFLALGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQFEENW YNTYASTLYKHLDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPRPVDPSKLPSMSRDL FRYK NT seq 555 nt NT seq  +upstreamnt  +downstreamnt atgagggaactaacacttgaagctcagcagcagtttgtccgagcaaaggaaataaccgaa ggctccagcagagtcagctacaggcagttgacagcctcatgtggctttaaggacatggga gctaagagggtgcaaaacaaagtcagcctagagggcaacgagtttgacatcaataataga aacggcattcactttcttgctctaggaatcctggagtttatcagcctggctgtggggttg atcagcatccggggagtggactctggcctgtacttaggaatgaatgagcgaggagaacta tatgggtcgaagaaactcacacgtgaatgtgttttccgggaacaatttgaagaaaactgg tacaacacctatgcttccaccttgtacaaacacttggactcggagagacagtattatgtg gccttgaataaagacggctcaccccgggagggatacaggactaaacgacaccagaaattc actcactttttgcccaggccagtagatccttctaagttgccctccatgtccagagacctc ttccgttataagtaa

Ursus maritimus (polar bear): 103676495 Help Entry 103676495         CDS       T03271                                  Gene name IGF1 Definition (RefSeq) insulin like growth factor 1   KO K05459   insulin-like growth factor 1 Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr01522   Endocrine resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04066   HIF-1 signaling pathway umr04068   FoxO signaling pathway umr04114   Oocyte meiosis umr04115   p53 signaling pathway umr04150   mTOR signaling pathway umr04151   PI3K-Akt signaling pathway umr04152   AMPK signaling pathway umr04211   Longevity regulating pathway umr04213   Longevity regulating pathway - multiple species umr04510   Focal adhesion umr04550   Signaling pathways regulating pluripotency of stem cells umr04730   Long-term depression umr04750   Inflammatory mediator regulation of TRP channels umr04913   Ovarian steroidogenesis umr04914   Progesterone-mediated oocyte maturation umr04935   Growth hormone synthesis, secretion and action umr04960   Aldosterone-regulated sodium reabsorption umr05200   Pathways in cancer umr05202   Transcriptional misregulation in cancer umr05205   Proteoglycans in cancer umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05224   Breast cancer umr05410   Hypertrophic cardiomyopathy umr05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103676495 (IGF1)    04014 Ras signaling pathway     103676495 (IGF1)    04015 Rap1 signaling pathway     103676495 (IGF1)    04066 HIF-1 signaling pathway     103676495 (IGF1)    04068 FoxO signaling pathway     103676495 (IGF1)    04151 PI3K-Akt signaling pathway     103676495 (IGF1)    04152 AMPK signaling pathway     103676495 (IGF1)    04150 mTOR signaling pathway     103676495 (IGF1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     103676495 (IGF1)    04115 p53 signaling pathway     103676495 (IGF1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103676495 (IGF1)    04550 Signaling pathways regulating pluripotency of stem cells     103676495 (IGF1)  09150 Organismal Systems   09152 Endocrine system    04913 Ovarian steroidogenesis     103676495 (IGF1)    04914 Progesterone-mediated oocyte maturation     103676495 (IGF1)    04935 Growth hormone synthesis, secretion and action     103676495 (IGF1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     103676495 (IGF1)   09156 Nervous system    04730 Long-term depression     103676495 (IGF1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     103676495 (IGF1)   09149 Aging    04211 Longevity regulating pathway     103676495 (IGF1)    04213 Longevity regulating pathway - multiple species     103676495 (IGF1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103676495 (IGF1)    05202 Transcriptional misregulation in cancer     103676495 (IGF1)    05205 Proteoglycans in cancer     103676495 (IGF1)   09162 Cancer: specific types    05214 Glioma     103676495 (IGF1)    05218 Melanoma     103676495 (IGF1)    05215 Prostate cancer     103676495 (IGF1)    05224 Breast cancer     103676495 (IGF1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     103676495 (IGF1)    05414 Dilated cardiomyopathy     103676495 (IGF1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103676495 (IGF1)    01522 Endocrine resistance     103676495 (IGF1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103676495 (IGF1) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103676495 (IGF1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Insulin DUF2865 Motif Other DBs NCBI-GeneID:  103676495 NCBI-ProteinID:  XP_008703915 UniProt:  A0A384DAX3 LinkDB All DBs Position Un AA seq 184 aa AA seqDB search MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVL CVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRA QRHTDMPKAQKYRPPSTTKKTKSQRRRKGGPKKRPGGEQKVGTETSQQMKGKKKEQRRET GARN NT seq 555 nt NT seq  +upstreamnt  +downstreamnt atgggaaaaatcagcagtcttccaactcaattatttaagtgctgcttttgtgatttcttg aaggtaaagatgcacatcatgtcctcctcgcatctcttctacctggccctgtgcttgctc accttcaccagctctgccacagctggaccggagacgctctgtggggctgaattggttctg tgtgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggctccagcagt cggagggcacctcagacaggcatcgtggatgagtgctgcttccggagctgtgatctgagg aggctagagatgtactgcgcacccctcaagcctgccaagtctgcccgctcagtccgtgcc cagcgccacactgacatgcccaaggctcagaagtatcgtcccccatctaccaccaagaaa acgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggggaacagaag gtggggacggaaacaagtcagcagatgaaaggaaagaagaaagagcagagaagggagact ggagctagaaactga

Ursus maritimus (polar bear): 103676520 Help Entry 103676520         CDS       T03271                                  Gene name PDGFB Definition (RefSeq) platelet derived growth factor subunit B   KO K17386   platelet-derived growth factor subunit B Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04072   Phospholipase D signaling pathway umr04151   PI3K-Akt signaling pathway umr04510   Focal adhesion umr04540   Gap junction umr04630   JAK-STAT signaling pathway umr04810   Regulation of actin cytoskeleton umr05167   Kaposi sarcoma-associated herpesvirus infection umr05200   Pathways in cancer umr05206   MicroRNAs in cancer umr05211   Renal cell carcinoma umr05214   Glioma umr05215   Prostate cancer umr05218   Melanoma umr05231   Choline metabolism in cancer umr05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103676520 (PDGFB)    04014 Ras signaling pathway     103676520 (PDGFB)    04015 Rap1 signaling pathway     103676520 (PDGFB)    04630 JAK-STAT signaling pathway     103676520 (PDGFB)    04020 Calcium signaling pathway     103676520 (PDGFB)    04072 Phospholipase D signaling pathway     103676520 (PDGFB)    04151 PI3K-Akt signaling pathway     103676520 (PDGFB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     103676520 (PDGFB)    04540 Gap junction     103676520 (PDGFB)   09142 Cell motility    04810 Regulation of actin cytoskeleton     103676520 (PDGFB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103676520 (PDGFB)    05206 MicroRNAs in cancer     103676520 (PDGFB)    05231 Choline metabolism in cancer     103676520 (PDGFB)   09162 Cancer: specific types    05214 Glioma     103676520 (PDGFB)    05218 Melanoma     103676520 (PDGFB)    05211 Renal cell carcinoma     103676520 (PDGFB)    05215 Prostate cancer     103676520 (PDGFB)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     103676520 (PDGFB)   09172 Infectious disease: viral    05167 Kaposi sarcoma-associated herpesvirus infection     103676520 (PDGFB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103676520 (PDGFB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103676520 (PDGFB)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103676520 (PDGFB) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103676520 (PDGFB) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103676520 (PDGFB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PDGF_N PDGF Motif Other DBs NCBI-GeneID:  103676520 NCBI-ProteinID:  XP_008703950 UniProt:  A0A384DB11 LinkDB All DBs Position Un AA seq 332 aa AA seqDB search MSGYQGQTVETVRGDQIKVSYSQEPGDAVSLRVPWSSQELYPTRRLDASAQKGSDLPKVT QLLSSQAGCEEAAKRESFTATPVSGCECRPRGCGFGLLAGDPIPEELYEMLSDHSIRSFD DLQRLLHGASVDEDGAELDLNLTRSHSGGELESLSRGRRSLGEAADENGDPSMVGARQGE LGYEKGRGQGPAIVWARASPLPAFGFRGKIPAGDTGVGRVGRRAPSAPACVVLQRHLDGS VLQVRKIEIVRKKPTFKKATVTLEDHLACKCETVVAARPVTRSLGSTQEQRAKTPQTRVT IRTVRVRRPPKGKHRKFKHTHDKKALKETLGA NT seq 999 nt NT seq  +upstreamnt  +downstreamnt atgtctgggtaccaagggcagacggtggagacagtgcgaggggaccagataaaggtgtcc tacagccaggagcccggcgatgcagtgagcctgcgggtcccgtggtcctcccaagaactc tatcccactcggaggctagatgcaagtgcacagaaaggaagtgacttgcccaaggtgacc cagctcctcagcagccaggcaggatgcgaagaagctgcaaagcgtgagtccttcaccgct acgcccgtgtcagggtgcgagtgccgccctcggggctgcgggtttggactcctggcgggg gaccccattcccgaggagctctacgagatgctgagtgaccactcgatccgctcctttgat gacctccagcgtctgctgcacggagcctccgtagacgaagacggggccgagctggacctg aatttgacccgatcccattctggaggcgagctggagagcttatcccgagggagaaggagc ctaggtgaggctgcagatgagaatggtgacccctccatggtgggagccagacaaggagaa ctgggctacgagaagggcagagggcaaggtcctgctattgtttgggccagggcctctcca ctcccggctttcggctttcgaggaaagatccctgcgggggacactggggtaggaagagta ggcaggcgggctccctcagcccctgcctgtgtggtcttacagaggcacttggatggttct gtccttcaggtgagaaaaatcgagattgtacggaagaagccaacctttaagaaggccacg gtgaccctggaggaccacctggcgtgcaagtgtgagacagtggtggctgctcgacctgtg acccgaagcctggggagtacccaggagcagcgagccaagacaccccaaactcgggtgacc attcggacggtgcgagtccgccggccccccaaggggaagcaccggaagttcaagcacacg catgacaagaaggcgctgaaggagaccctcggagcctag

Ursus maritimus (polar bear): 103676724 Help Entry 103676724         CDS       T03271                                  Gene name FGF7 Definition (RefSeq) fibroblast growth factor 7   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103676724 (FGF7)    04014 Ras signaling pathway     103676724 (FGF7)    04015 Rap1 signaling pathway     103676724 (FGF7)    04020 Calcium signaling pathway     103676724 (FGF7)    04151 PI3K-Akt signaling pathway     103676724 (FGF7)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103676724 (FGF7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103676724 (FGF7)   09162 Cancer: specific types    05226 Gastric cancer     103676724 (FGF7)    05218 Melanoma     103676724 (FGF7)    05224 Breast cancer     103676724 (FGF7)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103676724 (FGF7)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103676724 (FGF7) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103676724 (FGF7) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103676724 (FGF7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Fascin Motif Other DBs NCBI-GeneID:  103676724 NCBI-ProteinID:  XP_008704162 UniProt:  A0A384DAU4 LinkDB All DBs Position Un AA seq 194 aa AA seqDB search MRKWILTWILPTLLYRSCFHIICLVGTISLACNDMTPEQMATNVNCSSPERHTRSYDYME GGDIRVRRLFCRTQWYLRIDKRGKVKGTQEMKNSYNIMEIRTVAVGIVAIKGVESEYYLA MNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHSGGEMFVALNQKGVPVRGKKTK KEQKTAHFLPMAIT NT seq 585 nt NT seq  +upstreamnt  +downstreamnt atgcgcaaatggatactgacatggatcctgccaactttgctctacagatcatgctttcac attatctgtctagtgggcactatatctttagcttgcaatgacatgactccagagcaaatg gctacaaatgtgaactgttccagccctgagcgacatacaagaagttatgattacatggaa ggaggggatataagagtgagaagactcttctgtcgaacacagtggtatctgaggattgat aaacgaggcaaagtcaaaggaacccaagagatgaagaacagttacaatatcatggaaatc aggacagtggcagttggaattgtggcaatcaaaggggtggaaagtgaatactatcttgca atgaataaagaaggaaaactctatgcaaagaaagaatgcaatgaagattgcaacttcaaa gaattaattctggaaaaccattacaacacatatgcatcagctaaatggacacacagcgga ggagaaatgtttgttgctttaaaccaaaagggggttcctgtaagggggaaaaaaacgaag aaagaacaaaaaacagcccactttcttcctatggcaataacataa

Ursus maritimus (polar bear): 103681372 Help Entry 103681372         CDS       T03271                                  Gene name FGF20 Definition (RefSeq) fibroblast growth factor 20   KO K04358   fibroblast growth factor Organism umr  Ursus maritimus (polar bear) Pathway umr04010   MAPK signaling pathway umr04014   Ras signaling pathway umr04015   Rap1 signaling pathway umr04020   Calcium signaling pathway umr04151   PI3K-Akt signaling pathway umr04810   Regulation of actin cytoskeleton umr05200   Pathways in cancer umr05218   Melanoma umr05224   Breast cancer umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     103681372 (FGF20)    04014 Ras signaling pathway     103681372 (FGF20)    04015 Rap1 signaling pathway     103681372 (FGF20)    04020 Calcium signaling pathway     103681372 (FGF20)    04151 PI3K-Akt signaling pathway     103681372 (FGF20)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     103681372 (FGF20)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103681372 (FGF20)   09162 Cancer: specific types    05226 Gastric cancer     103681372 (FGF20)    05218 Melanoma     103681372 (FGF20)    05224 Breast cancer     103681372 (FGF20)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:umr04052]     103681372 (FGF20)    00536 Glycosaminoglycan binding proteins [BR:umr00536]     103681372 (FGF20) Cytokines and growth factors [BR:umr04052]  Growth factors   Growth factors (RTK binding)    103681372 (FGF20) Glycosaminoglycan binding proteins [BR:umr00536]  Heparan sulfate / Heparin   Growth factors/receptors    103681372 (FGF20) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  FGF Motif Other DBs NCBI-GeneID:  103681372 NCBI-ProteinID:  XP_008709157 UniProt:  A0A384DQ18 LinkDB All DBs Position Un AA seq 215 aa AA seqDB search MNQIKKKDERKVGFAELEPQPPAPAGYWQRQLIDVPAKPAAGSHLPKERRSLQDSENSPA ISVQSPLSDLTGLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSG LYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPR DGARSKRHQKFTHFLPRPVDPERVPELYKDILMYS NT seq 648 nt NT seq  +upstreamnt  +downstreamnt atgaaccaaattaagaagaaggacgagcgaaaagttgggtttgcggagttggagcctcag cccccagccccagccgggtattggcagcggcagcttatagatgttcctgcaaagccagca gccggctcccacctccccaaggagagaagatcgctccaagacagtgaaaactcccctgct atctcagtgcaaagtccactcagcgacctcacaggactctactgccgcacgggcttccac ctgcagatcttgccggacggcagcgtgcagggcacccggcaggaccacagcctcttcggt atcctggaattcatcagtgtggcagtgggactggtcagtattagaggtgtggacagtggt ctttaccttggaatgaatgacaaaggagaactctatggctcagagaaattgacttctgaa tgcatctttagggagcaatttgaagagaactggtataatacctattcatccaacatatat aaacatggggacactggccgtaggtattttgtggcacttaacaaagacggaactccaaga gatggtgccaggtccaaaagacatcagaaattcacacatttcctgcctagaccagtggat ccagagagagttcccgaattgtacaaggacatcctgatgtacagctga

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