Ursus maritimus (polar bear): 103659742
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Entry
103659742 CDS
T03271
Gene name
CASP8
Definition
(RefSeq) caspase 8
KO
K04398
caspase 8 [EC:
3.4.22.61
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01524
Platinum drug resistance
umr04115
p53 signaling pathway
umr04210
Apoptosis
umr04215
Apoptosis - multiple species
umr04217
Necroptosis
umr04620
Toll-like receptor signaling pathway
umr04621
NOD-like receptor signaling pathway
umr04622
RIG-I-like receptor signaling pathway
umr04625
C-type lectin receptor signaling pathway
umr04657
IL-17 signaling pathway
umr04668
TNF signaling pathway
umr04932
Non-alcoholic fatty liver disease
umr05010
Alzheimer disease
umr05016
Huntington disease
umr05022
Pathways of neurodegeneration - multiple diseases
umr05132
Salmonella infection
umr05134
Legionellosis
umr05142
Chagas disease
umr05145
Toxoplasmosis
umr05152
Tuberculosis
umr05160
Hepatitis C
umr05161
Hepatitis B
umr05162
Measles
umr05163
Human cytomegalovirus infection
umr05164
Influenza A
umr05165
Human papillomavirus infection
umr05167
Kaposi sarcoma-associated herpesvirus infection
umr05168
Herpes simplex virus 1 infection
umr05169
Epstein-Barr virus infection
umr05170
Human immunodeficiency virus 1 infection
umr05200
Pathways in cancer
umr05203
Viral carcinogenesis
umr05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
103659742 (CASP8)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
103659742 (CASP8)
04215 Apoptosis - multiple species
103659742 (CASP8)
04217 Necroptosis
103659742 (CASP8)
04115 p53 signaling pathway
103659742 (CASP8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103659742 (CASP8)
04621 NOD-like receptor signaling pathway
103659742 (CASP8)
04622 RIG-I-like receptor signaling pathway
103659742 (CASP8)
04625 C-type lectin receptor signaling pathway
103659742 (CASP8)
04657 IL-17 signaling pathway
103659742 (CASP8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103659742 (CASP8)
05203 Viral carcinogenesis
103659742 (CASP8)
09164 Neurodegenerative disease
05010 Alzheimer disease
103659742 (CASP8)
05016 Huntington disease
103659742 (CASP8)
05022 Pathways of neurodegeneration - multiple diseases
103659742 (CASP8)
09166 Cardiovascular disease
05416 Viral myocarditis
103659742 (CASP8)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
103659742 (CASP8)
09171 Infectious disease: bacterial
05132 Salmonella infection
103659742 (CASP8)
05134 Legionellosis
103659742 (CASP8)
05152 Tuberculosis
103659742 (CASP8)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
103659742 (CASP8)
05161 Hepatitis B
103659742 (CASP8)
05160 Hepatitis C
103659742 (CASP8)
05164 Influenza A
103659742 (CASP8)
05162 Measles
103659742 (CASP8)
05168 Herpes simplex virus 1 infection
103659742 (CASP8)
05163 Human cytomegalovirus infection
103659742 (CASP8)
05167 Kaposi sarcoma-associated herpesvirus infection
103659742 (CASP8)
05169 Epstein-Barr virus infection
103659742 (CASP8)
05165 Human papillomavirus infection
103659742 (CASP8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
103659742 (CASP8)
05142 Chagas disease
103659742 (CASP8)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
103659742 (CASP8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
umr01002
]
103659742 (CASP8)
Enzymes [BR:
umr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.61 caspase-8
103659742 (CASP8)
Peptidases and inhibitors [BR:
umr01002
]
Cysteine peptidases
Family C14: caspase family
103659742 (CASP8)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Peptidase_C14
DED
Motif
Other DBs
NCBI-GeneID:
103659742
NCBI-ProteinID:
XP_008685573
UniProt:
A0A384BTK5
LinkDB
All DBs
Position
Un
AA seq
486 aa
AA seq
DB search
MNFSKCLYNIGEQLDSDELASLKFLSMDYIPQKKQEPIKDPLMLFQRLQEKRMLEESNLS
FLKELLFRINRLDLLVTYLDTSKEEMEQELQIPGRAQISAYRVMLFQISEDVSKLELRSF
KFFLSQEISRCKLHDDLNLFDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE
LSREQTLSPQRSLDEISNDMSQLLVGEESLRVPPMSDSPGEQDCEPETSDKVYRMESKPR
GYCLIFNNYDFSIARKEVPKLQSIKDRNGTDLDADALCQTFSELHFEIVPFKDCTAKKIC
EVLKSYQSMDHSSRDCFICCILSHGDKGIIYGSDGQEVPIYELTSYFTGSKCPSLAGKPK
IFFIQACQGDNYQKGIAVETDSEQKEAYLEMDSSYQKRYIPEDADFLLGMATVNNCVSYR
NPMEGTWYIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDRKNMGKQMPQPTFTLRKK
LFFPLN
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgaatttcagcaaatgcctctataatattggagaacagctggacagtgatgagctggcc
tccctcaagttcctgagcatggactacatcccacagaagaagcaggaacccatcaaggat
cccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc
ttcttgaaggagctgcttttccgaattaacagactggacctgctggttacctacctggac
accagcaaggaggagatggagcaggagcttcaaataccaggcagagcccagatctctgcc
tacagggtcatgctttttcagatttcagaagatgtaagcaaattggaattgaggtccttt
aagttttttttgagccaggagatctccagatgtaaactgcacgatgacttgaacttgttt
gatattttcatagagatggagaagagggtcatcctcggggaaagaaatctggataccctg
aaaagaatctgtgaccaaattaacaagagcctgctgaagaaaatcacggattatgaagaa
ttaagcagagagcaaacactgagccctcaaagaagtctagatgaaatttcaaatgatatg
tctcagttgcttgtaggggaggaatccctgagggtaccgccaatgtcggactctccagga
gaacaggactgtgaaccagagacatcggacaaagtttaccgaatggaaagcaaacctcga
ggatattgtttgatctttaacaattacgactttagcatagcacggaaggaagtgcccaaa
cttcagagcattaaggataggaatggaacagacttggatgcagatgctttgtgtcagacc
tttagtgagcttcattttgagatcgtgcctttcaaagactgtacagccaagaaaatctgt
gaggttctgaaatcctaccaaagcatggaccactctagcagggattgcttcatctgctgc
atcctctcccatggagacaagggcatcatctatggctctgatgggcaagaagtccccatc
tatgagctgacttcttacttcactggttcaaagtgcccttcccttgcaggcaagcccaaa
atcttttttattcaggcttgtcaaggggataactaccagaaaggtatagctgttgagact
gactctgaacagaaggaggcctatttagaaatggactcatcctatcagaagagatatatc
ccagaagatgctgactttctgctggggatggccactgtgaataattgtgtttcctaccga
aaccccatggaggggacctggtatatccagtcactttgccagagcctgagagaaagatgt
cctaggggcgaagatattctcaccatccttaccgaggtgaactttgaagtgagcaataag
gatgacaggaaaaacatggggaaacaaatgccacaacctactttcacactgaggaaaaaa
ctctttttccctcttaattga
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