Ursus maritimus (polar bear): 103664318
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Entry
103664318 CDS
T03271
Gene name
FLT3
Definition
(RefSeq) fms related tyrosine kinase 3
KO
K05092
fms-related tyrosine kinase 3 [EC:
2.7.10.1
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04010
MAPK signaling pathway
umr04014
Ras signaling pathway
umr04151
PI3K-Akt signaling pathway
umr04640
Hematopoietic cell lineage
umr05200
Pathways in cancer
umr05202
Transcriptional misregulation in cancer
umr05221
Acute myeloid leukemia
umr05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103664318 (FLT3)
04014 Ras signaling pathway
103664318 (FLT3)
04151 PI3K-Akt signaling pathway
103664318 (FLT3)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
103664318 (FLT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103664318 (FLT3)
05202 Transcriptional misregulation in cancer
103664318 (FLT3)
05230 Central carbon metabolism in cancer
103664318 (FLT3)
09162 Cancer: specific types
05221 Acute myeloid leukemia
103664318 (FLT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103664318 (FLT3)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
umr04090
]
103664318 (FLT3)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
103664318 (FLT3)
Protein kinases [BR:
umr01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
103664318 (FLT3)
CD molecules [BR:
umr04090
]
Proteins
103664318 (FLT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
ig
Ig_3
Ig_2
APH
Motif
Other DBs
NCBI-GeneID:
103664318
NCBI-ProteinID:
XP_008690404
UniProt:
A0A384C7G0
LinkDB
All DBs
Position
Un
AA seq
974 aa
AA seq
DB search
MTFETITNQDLPVIKCVLINHKNNDSSLGISSSYPMASGPPEDLGCALKPESTQAVYGAA
TVEVDMLASITLQVLVNTPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAG
EYLLFIQSEATNYTILFTVSIRSTLLYTLRRPFFRKMENQDALVCISESIPEPTVEWVFC
DSQSESCKGESPAVVTKEGSVLHELFGTDIRCCARNELGRECTKLFTIDLNQTPQTTPPQ
LFLKVGEPLWIRCKAVHVNHGFGLSWELENKALEEGRYFEMSTYSTNRTMIRVLFAFVTS
VGRNDTGYYTCSSSEHPSKSALVTILEKGFINASKSNEDYEIDQYEEFCFSVRFKAYPQI
RCTWTFSRKSFPCEQSGLDDGYSISKFCNHKHQPGEYIFHAENDDAEFTKMFTLNIRRKP
QVLAETSASQASCSSDGYPLPSWTWKKCSDKSSNCTEEITEGIWNIKANRKVFGQWISSS
TLNMSEAMKGFLVKCCAYNSLGTSCETILLNSSGPFPFIQDNISFYATVGLCLPFIAILT
MLICHKYKKQFRYESQLQMVQVTGSLDNEYFYIDFREYEYDLKWEFPRENLEFGKVLGSG
AFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTHLGNHENIVNLLG
ACTLSGPIYLIFEYCCYGDLLNYLRNKREKFHRTWTEIFKEHNFSFYPTFQSQPNSSMPG
SREVQIHQDLDHISGFNGNSFQSEDETEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGM
EFLEFKSCVHRDLAARNVLVTHGKGVKICDFGLARDIRSDSNYVVRGNARLPVKWMAPES
LFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQSGFKMDQPFYATEEIY
FIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNTDGHVSDRPSGYQNRRPYSREV
DSGLLAPQGHGEDS
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgacatttgagactattacaaatcaagatctgcctgtgatcaagtgtgttttaatcaat
cataagaacaatgattcatcactggggatatcatcatcgtatcccatggcatcaggaccc
ccagaagacctcgggtgtgccttgaagcctgagagcacacaggcggtctatggagcagcc
actgtggaagtggacatgttggcatccatcacactccaagtactggtcaacaccccgggg
aacatttcctgtctctgggtctttaaacacagctccctgaattgccagccccactttgat
ttacagaacagaggagttgtttccatggtcattttgaaaatgacagaaacccaagctgga
gaatacctacttttcattcagagtgaagctaccaattacacaatactgtttacagtgagt
ataagaagtacactgctttacacattaaggagacctttcttcagaaaaatggaaaatcag
gacgccctggtctgcatatctgagagcattccagaaccgaccgtggaatgggtgttctgc
gattcacagagtgaaagctgtaaaggggagagtcccgctgttgttacaaaggagggaagt
gtgcttcatgagctgtttggaacagacataaggtgctgtgcaagaaacgagctgggcagg
gagtgtaccaagctgttcacaatagatctaaatcagacgcctcagaccacaccgccacag
ttatttctgaaagtaggggaacccttgtggataaggtgcaaagccgttcatgtaaaccac
ggattcggactcagctgggagctagaaaataaagccctggaagagggccgctactttgag
atgagtacctactccacaaacagaactatgatacgggtcctgtttgctttcgtaacatcc
gtgggaaggaacgacaccggctattacacctgttcctcctcagagcatcccagtaaatca
gctttggttaccatcctagaaaagggatttataaacgcttccaaatcaaatgaagattat
gagattgaccagtatgaagagttttgtttttctgtcaggtttaaagcgtacccacaaatc
agatgtacatggaccttctctcgaaaatcgtttccttgtgagcagagtggccttgatgat
gggtacagcatatctaagttttgcaaccataaacaccagccaggagaatatatattccat
gcagaaaatgatgatgccgaattcacaaaaatgttcacgctgaacataagaaggaaacct
caggtgctagccgagacgtcagcaagtcaggcttcgtgttcctctgacggctacccctta
ccatcttggacctggaagaagtgttcagacaagtcttccaactgcacagaggagatcaca
gaaggaatttggaatataaaggctaacagaaaagtgttcggccagtggatatcgagcagc
acccttaacatgagtgaggccatgaagggattcctggtgaagtgctgtgcctacaattcc
cttggcacatcttgtgaaacaatccttttaaactcgtcagggcccttccctttcatccaa
gacaacatctccttctatgcaacagtcgggctttgtcttcccttcattgccattctaacc
atgctaatttgtcacaagtacaaaaagcaatttaggtatgagagccagctgcaaatggtg
caggtgaccggctctttggataatgagtacttctacattgatttcagagaatatgaatat
gatctcaaatgggagtttccaagagaaaatttagaatttgggaaagtactaggatcgggt
gctttcggaaaagtgatgaatgcaacagcttatggaattagtaaaacaggagtctcaatc
caggtggcagtcaaaatgctgaaagaaaaggcagacagttctgaaagagaggctctcatg
tctgaactcaaaatgatgactcacctgggaaaccacgagaatatcgtgaatctgctgggg
gcatgcacactgtcaggaccaatttacttgatttttgaatattgttgctatggtgatctt
ctcaactatctaagaaataaaagagaaaaatttcacaggacatggacagagattttcaag
gaacacaatttcagtttttaccccactttccaatcacaaccaaattccagtatgcctggt
tcaagagaagttcagatacaccaggacttggatcatatctcagggttcaatgggaattca
tttcaatccgaagatgaaactgaatatgaaaaccaaaaaaggctggaggaagaagaggac
ttgaatgtgctgacatttgaagaccttctttgctttgcctaccaagttgccaaaggaatg
gaatttctggaatttaagtcgtgtgttcacagagacctggcagccaggaacgtgctcgtg
acccacgggaaaggggtgaagatctgcgatttcggactggcccgggatatcaggagtgac
tccaactatgttgtcaggggcaacgctcgtctgcccgtaaagtggatggcccctgagagc
ttatttgaggggatctacaccataaagagtgacgtctggtcgtatggaatattactctgg
gaaatattctcgcttggtgtcaatccgtaccctggtattccggttgatgctaatttctat
aaactcattcaaagcggatttaagatggatcagccgttttatgctacggaagaaatatac
tttataatgcaatcctgctgggcttttgactcaaggaaacggccgtccttccccaatcta
acttcatttttgggatgtcagctggcagacgccgaagaagcgatgtatcagaacacggat
ggccacgtctcagaccgtccttccggctaccagaacaggcgaccttacagtagagaggtg
gattccgggctcctggctccccagggtcatggtgaagactcctag
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