KEGG   Ursus maritimus (polar bear): 103667783Help
Entry
103667783         CDS       T03271                                 

Gene name
HKDC1
Definition
(RefSeq) hexokinase domain containing 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00010  Glycolysis / Gluconeogenesis
umr00051  Fructose and mannose metabolism
umr00052  Galactose metabolism
umr00500  Starch and sucrose metabolism
umr00520  Amino sugar and nucleotide sugar metabolism
umr00524  Neomycin, kanamycin and gentamicin biosynthesis
umr01100  Metabolic pathways
umr01200  Carbon metabolism
umr04066  HIF-1 signaling pathway
umr04910  Insulin signaling pathway
umr04930  Type II diabetes mellitus
umr04973  Carbohydrate digestion and absorption
umr05230  Central carbon metabolism in cancer
Module
umr_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
umr_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:umr00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    103667783 (HKDC1)
   00051 Fructose and mannose metabolism
    103667783 (HKDC1)
   00052 Galactose metabolism
    103667783 (HKDC1)
   00500 Starch and sucrose metabolism
    103667783 (HKDC1)
   00520 Amino sugar and nucleotide sugar metabolism
    103667783 (HKDC1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    103667783 (HKDC1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    103667783 (HKDC1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103667783 (HKDC1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    103667783 (HKDC1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    103667783 (HKDC1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103667783 (HKDC1)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     103667783 (HKDC1)
Membrane trafficking [BR:umr04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    103667783 (HKDC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 VPS13_mid_rpt
Motif
Other DBs
NCBI-GeneID: 103667783
NCBI-ProteinID: XP_008694190
LinkDB All DBs
Position
Un
AA seq 917 aa AA seqDB search
MFAVHLMAFYFSKLKEDQIKKVDRFLYDMRLSDETLLDIMTRFQAEMQKGLGKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVSQEGKRNVQMESQFYPTPNEIIR
GNGSELFDYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV
QDTDVVSCLTKAMRKHKDIDVDILALVNDTVGTLMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCVNTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRIILLKMAKAGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRVNKKLARLRTTVGMDGTVYKIH
PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFQLT
REQLEDVRGKMRVEFEYGLKKDTHLTATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT
FSFPCRQTSIDKGTLIEWTKGFKATDCEGEDMVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGHEDPNCEIGLIAGTGSNMCYMEEMRNIELVEGDEGKMCINTEWGGFGDNGCIDDI
RTQYDKKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAV
VEKRREDQGLEYLKITVGVDGTLYKLHPHFSRILQETVKELAPRCDVMLMLSEDGSGKGA
ALITAVAKRLQQAQKEN
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgtttgcggtacacttgatggcattttacttcagcaagctgaaggaagatcagatcaag
aaggtggacaggttcctgtatgacatgcggctctccgatgagacccttttggacatcatg
actcgcttccaggctgaaatgcagaagggcctggggaaggacaccaaccccacagccgcc
gtgaagatgctgcccacctttgtcagggccattccagatggctcagaaaatggggagttt
ctttctctggatcttggagggtccaaatttcgtgtcttgaaggtacaagtctctcaagag
gggaaaagaaacgtccagatggagagtcagttctacccaacacccaatgaaattatccga
ggcaatggctccgagctgtttgactacgtagctgactgtctggcagatttcatgaagacg
aaagggttgaagcataagaaattgccccttggcctaaccttctcttttccgtgcagacag
actaagttggaagaggggatcctgctttcatggaccaagaagtttaaggcacggggagtt
caagacacagatgtcgtgagttgtctgaccaaagccatgagaaaacacaaggacatagac
gtggacatcctggccttggtcaatgacaccgtggggaccctgatgacatgcgcctatgat
gatccctactgtgaagttggtgtcatcattggcaccggcaccaacgcgtgttacatggag
gacatgagcaacattgacctggtggagggcgatgaggggaggatgtgcgtcaacacggag
tggggggccttcggcgacgacggggctctggaagacatccgcaccgagttcgaccgggag
ctggacctcggctctctcaaccccgggaagcaactgtttgagaagatgatcagtggcctg
tacctgggtgaacttgtcaggatcatcttgctgaagatggccaaggcaggtctcctgttt
ggcggcaagaagtcctctgctctccacacaaagggcaagattgaaacacggcacgtggct
gccatggagaagtataaggaaggccttgccaatacaagagagatcctgacagatctgggc
ctggagccttcggaggccgactgcatcgcggtccagcacgtctgcaccatcgtctccttc
cgttcagccaacctgtgtgcagcggccctggcagccatcctgacgcgcctgcgggtgaac
aagaagctggcacggctccgcaccacggtgggcatggacggcacggtctacaagatacac
cctcaataccccaaacgcctgcacaaagtggtgaggagactggtcccgaactgtgacgtc
cgcttcctcttgtcggagagtggcagcaccaagggggctgccatggtgacagcggtggcc
tcccgagtgcaggcccagcggaagcagatcgacaaggtgctggctctgttccagctgact
cgagagcagcttgaggacgtgcggggcaagatgcgggttgagttcgagtacgggctgaaa
aaggacacccacctgacagccacagtcaagatgctgcccacctacgtctgcgggatgcca
gatggcacagagaaaggaaagttccttgccctggatctggggggaaccaacttccgggtc
ctcctggtaaagatcagaagcggacggaggtcggtgcgaatgtacaacaagatctttgcc
atccccttggagatcatgcagggcaccggcgaggagctgttcgatcacatcgtgcagtgc
attgctgacttcctggactacatgggcctcaagggagcccagctgcctttgggcttcacg
ttctcatttccctgcaggcagacgagcatcgacaagggaacgctcattgagtggaccaaa
ggcttcaaggccacggattgtgaaggggaagacatggtggacatgctcagggaagccatc
aagaggagaaatgagttcgacctggacatagttgcagttgtgaatgacacagtggggacc
atgatgacctgcggccatgaagatcctaattgtgagattggcctgattgcaggaacaggc
agcaacatgtgctacatggaggagatgaggaacattgagctggtggaaggggacgaaggg
aagatgtgcattaacacagaatggggaggatttggagataatggctgcatagacgacatc
cggacccaatatgacaagaaggtggatgaggggtccttgaaccctggcaaacagagatat
gagaaaatgaccagtgggatgtacctgggggagattgtgcggcagatcctgattgacctg
accaagcagggtctccttttccgtgggcagatttcagagcgtctccggaccaggggcatc
tttgaaaccaagttcctgtcccagattgaaagtgatcggctggccctcctccaggtcagg
aggatcctgcagcagctcggcctggacagcacatgtgaggacagcattgtggtgaaggag
gtgtgcggagctgtgtcccggcgggcggcccagctctgcggcgctggcctggctgctgtc
gtggagaagaggagggaagaccaggggctggagtacctgaagatcaccgtgggagtggat
ggcacgctgtacaagctgcacccgcacttttctcggatattgcaggaaactgtgaaagag
ctagctcctcgatgtgatgtgatgctcatgctgtctgaagatgggagtggaaagggagct
gctctgatcactgctgtggccaagaggttacagcaggcccagaaggagaactag

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