KEGG   Ursus maritimus (polar bear): 103668837Help
Entry
103668837         CDS       T03271                                 

Gene name
HDAC6
Definition
(RefSeq) histone deacetylase 6
  KO
K11407  histone deacetylase 6 [EC:3.5.1.98]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr05034  Alcoholism
umr05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09160 Human Diseases
  09161 Cancers: Overview
   05203 Viral carcinogenesis
    103668837 (HDAC6)
  09165 Substance dependence
   05034 Alcoholism
    103668837 (HDAC6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:umr01009]
    103668837 (HDAC6)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:umr03019]
    103668837 (HDAC6)
   04131 Membrane trafficking [BR:umr04131]
    103668837 (HDAC6)
   03036 Chromosome and associated proteins [BR:umr03036]
    103668837 (HDAC6)
Enzymes [BR:umr01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     103668837 (HDAC6)
Protein phosphatases and associated proteins [BR:umr01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     103668837 (HDAC6)
Messenger RNA biogenesis [BR:umr03019]
 Eukaryotic Type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     103668837 (HDAC6)
Membrane trafficking [BR:umr04131]
 Autophagy
  Aggrephagy
   Other aggrephagy associated proteins
    103668837 (HDAC6)
Chromosome and associated proteins [BR:umr03036]
 Eukaryotic Type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class II HDACs
     103668837 (HDAC6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hist_deacetyl zf-UBP zf-UBP_var PKI
Motif
Other DBs
NCBI-GeneID: 103668837
NCBI-ProteinID: XP_008695381
UniProt: A0A384CKM0
LinkDB All DBs
Position
Un
AA seq 970 aa AA seqDB search
MTSTGQDSTTTRQRRSRHNPHSPPHDSSVTSKRGVKKGALLHSSPSLAEVKKKGRMKKLS
QAAEQDLIVGLQGLDLNLEAKTLSGTGLVFDEQLNEFHCLWDDSFPECPERLHAIKEQLI
QEGLVDRCVSFQARFAEKEELMLVHSLEYIDLMETTQYMNEGELRILADTYDSVYLHPNS
YTCACLASGSVLRLVDAVLGNEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARQAXX
XXXXXXXLIVDWDVHHGQGTQFAFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTIGFGRG
QGYTINVPWNQVGMRDADYIAAFLHLLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
AGLAQLTHLLMGLAGGKLILSLEGGYNFRSLAEGVSASLHTLLGDPCPILESPGAPCRSA
QASLSCALEALEPFWEVLVRSAETLEEDFLEEENVEKEEEGPWQPPALPILTCSSSCVSA
ILSLFVLCLFVLPLLFSGLWSCVPQSPGLQLSDWRLCVSGVPSPAGYPGLHAHAHVSLLS
LLQFNPELVLVSAGFDAARGDPLGGCQVSPEGYAHLTHLLMGLANGRIILILEGGYNLTS
ISESMAACTRSLLRDPPPLPPLSGALASITETIQVHRRYWRSLRVMKVEDKEGPSSSKSI
TRKVTPPAHRGSAVRMTAPDGNILDADTGKATSASSVEVSTPDQAKSETAVVALNQDQAS
DAPTREAMLDKTPSEAAAEGATLDFPTIGGMATVGATPGQTTSEEAVGGAEVIQTPPALH
TDSQTPPASSVQGATAQISPSKLTESLGTLDLNSEAQAPESQSPEEERLLGEAAEGQHRD
HSMLIQSFGDHAVGDQVAFYAVTPLPWCPHLVAVGPIPESGLDVTQPCQDCGTLRENWVC
LSCYQVYCGRYVSAHMLQHHGVSGHPLVLSYVDLSTWCYDCEAYVHHQALLDVKSLAHQN
KFGEDMPHSH
NT seq 2913 nt NT seq  +upstreamnt  +downstreamnt
atgacctccaccggccaggattccaccacaaccaggcagcgaaggagtaggcataacccc
cattcgcccccccacgactccagcgtcacctcgaagcgaggtgttaagaagggtgcctta
ctccactccagccctagtctagcagaggtaaagaagaaaggcagaatgaagaagctcagc
caagcagcagagcaagacctcatcgtgggcctgcaaggactggatctgaaccttgaggcc
aagacactgtctgggactggtttggtgttcgatgagcagctaaatgaattccactgcctc
tgggatgacagcttccctgaatgccctgagcggctccatgccatcaaggaacagctgatc
caggagggccttgtggaccgctgcgtgtccttccaggctcgctttgctgaaaaggaggag
ctgatgttggttcacagcctggaatacattgacctgatggagacgacccagtacatgaat
gagggagagctccgcatcctagcagacacctatgactcagtttacctgcatccgaactca
tatacctgtgcctgcctggcctcgggctctgtcctcaggctggtggatgcggtcctgggg
aatgagatccggaatggcatggccatcatcaggcctccaggacaccacgcccagcacagt
cttatggatggatattgcatgttcaaccacgtggctgtggccgcccgccaggcnnnnnnn
nnnnnnnnnnnnnnnnnnnttcttatcgtggattgggatgtgcaccatggtcaaggaaca
cagtttgcctttgaccaggaccccagtgtcctctatttctccatccaccgctacgagcag
ggtaggttctggccccacctgaaggcctctaactggtccaccataggttttggccgaggc
cagggatataccatcaatgtgccttggaaccaggtggggatgcgcgatgccgactacatt
gccgctttcctgcacctccttctgccagtcgcccttgagttccagccccagctggtcctg
gtggccgctggatttgacgccctccaaggggaccccaagggtgagatggccgccactccg
gcaggactcgctcagctaacgcacctgctcatgggtctggcaggcggcaagctgatcctg
tctctggagggtggctacaacttccgctccctggctgagggcgtcagtgcctcactccac
acccttctgggagacccttgccccatactggagtctcctggtgccccgtgccggagtgcc
caggcgtcactgtcctgtgctctggaagccctggagcccttctgggaggtccttgtaaga
tcagctgagaccctggaggaggacttcttggaggaggagaatgtggagaaggaagaagaa
ggaccgtggcagcccccggcgctcccaatcctgacgtgctccagctcctgtgtctctgcg
atcctgagtctgtttgtcctgtgtctcttcgtcctccccttgctattttcggggctctgg
tcttgtgtcccccagtctccaggtctccagctctccgactggcgtctgtgcgtgtctggg
gtgccctcacctgctgggtacccaggcctccatgctcacgcccatgtgtctcttctctcc
ctgcttcagtttaacccagaactggtgctggtctcggctggctttgacgccgcacggggg
gacccgctggggggctgccaggtgtcacccgagggctatgcccacctcacccacctgctg
atgggccttgccaatggccgcatcatcctaatcctagagggtggctacaacctgacctcc
atctcggagtccatggctgcctgcacccgttccctccttcgggacccaccaccactgccc
ccgctgtcaggggccctggcctccatcaccgagaccatccaagtccatcgcagatactgg
cgcagcttgcgggtcatgaaggtcgaagacaaggagggaccttccagttctaagtcaatc
accaggaaggtgaccccgccagcccaccgtgggtcagctgtgcggatgaccgcaccagac
gggaacattctagatgcggacacagggaaggctacctcagcatcatccgtggaagtgtcc
accccagaccaagctaagtcagagactgcagtggtggcactcaatcaggaccaagcctca
gacgctcccaccagggaagccatgctggacaagaccccctcagaggcagccgcagaagga
gccacgctggattttccaaccatcggggggatggccacagttggagccacgccaggccag
accacctcagaggaagctgtcgggggagctgaggtgatccaaacccctccagccttacac
actgacagccagactcccccagcctcatctgtgcaaggagccacagcccagatatccccc
agtaagctgactgagagtctcgggaccttggacctgaacagcgaggctcaggcaccagaa
tctcagagcccagaagaggagagactgctaggagaggcagctgaaggtcagcacagggat
cattccatgctgattcagagctttggggaccatgccgtcggtgaccaggtcgcgttttat
gcggtgacaccactgccctggtgtccccatttggtggcagtaggtcccatacctgaatcg
ggcctggacgtgacccaaccttgtcaggactgtggaacactccgggagaactgggtgtgt
ctgtcctgctatcaggtctactgcggccgttacgtcagtgcgcatatgctgcagcaccac
ggcgtctcaggacacccgctggtcctcagctacgtcgacctgtctacctggtgttacgac
tgtgaggcctatgtccaccaccaggctctcctggatgtgaagagcctcgctcaccagaac
aagtttggggaggacatgccccactcgcactaa

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