Ursus maritimus (polar bear): 103669776
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Entry
103669776 CDS
T03271
Gene name
SRC
Definition
(RefSeq) SRC proto-oncogene, non-receptor tyrosine kinase
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01521
EGFR tyrosine kinase inhibitor resistance
umr01522
Endocrine resistance
umr04012
ErbB signaling pathway
umr04015
Rap1 signaling pathway
umr04062
Chemokine signaling pathway
umr04137
Mitophagy - animal
umr04144
Endocytosis
umr04360
Axon guidance
umr04370
VEGF signaling pathway
umr04510
Focal adhesion
umr04520
Adherens junction
umr04530
Tight junction
umr04540
Gap junction
umr04611
Platelet activation
umr04625
C-type lectin receptor signaling pathway
umr04727
GABAergic synapse
umr04750
Inflammatory mediator regulation of TRP channels
umr04810
Regulation of actin cytoskeleton
umr04912
GnRH signaling pathway
umr04915
Estrogen signaling pathway
umr04917
Prolactin signaling pathway
umr04919
Thyroid hormone signaling pathway
umr04921
Oxytocin signaling pathway
umr04926
Relaxin signaling pathway
umr05100
Bacterial invasion of epithelial cells
umr05135
Yersinia infection
umr05152
Tuberculosis
umr05161
Hepatitis B
umr05163
Human cytomegalovirus infection
umr05167
Kaposi sarcoma-associated herpesvirus infection
umr05168
Herpes simplex virus 1 infection
umr05203
Viral carcinogenesis
umr05205
Proteoglycans in cancer
umr05219
Bladder cancer
umr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
103669776 (SRC)
04015 Rap1 signaling pathway
103669776 (SRC)
04370 VEGF signaling pathway
103669776 (SRC)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103669776 (SRC)
04137 Mitophagy - animal
103669776 (SRC)
09144 Cellular community - eukaryotes
04510 Focal adhesion
103669776 (SRC)
04520 Adherens junction
103669776 (SRC)
04530 Tight junction
103669776 (SRC)
04540 Gap junction
103669776 (SRC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
103669776 (SRC)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103669776 (SRC)
04625 C-type lectin receptor signaling pathway
103669776 (SRC)
04062 Chemokine signaling pathway
103669776 (SRC)
09152 Endocrine system
04912 GnRH signaling pathway
103669776 (SRC)
04915 Estrogen signaling pathway
103669776 (SRC)
04917 Prolactin signaling pathway
103669776 (SRC)
04921 Oxytocin signaling pathway
103669776 (SRC)
04926 Relaxin signaling pathway
103669776 (SRC)
04919 Thyroid hormone signaling pathway
103669776 (SRC)
09156 Nervous system
04727 GABAergic synapse
103669776 (SRC)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
103669776 (SRC)
09158 Development and regeneration
04360 Axon guidance
103669776 (SRC)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
103669776 (SRC)
05203 Viral carcinogenesis
103669776 (SRC)
09162 Cancer: specific types
05219 Bladder cancer
103669776 (SRC)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
103669776 (SRC)
09171 Infectious disease: bacterial
05135 Yersinia infection
103669776 (SRC)
05152 Tuberculosis
103669776 (SRC)
05100 Bacterial invasion of epithelial cells
103669776 (SRC)
09172 Infectious disease: viral
05161 Hepatitis B
103669776 (SRC)
05168 Herpes simplex virus 1 infection
103669776 (SRC)
05163 Human cytomegalovirus infection
103669776 (SRC)
05167 Kaposi sarcoma-associated herpesvirus infection
103669776 (SRC)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
103669776 (SRC)
01522 Endocrine resistance
103669776 (SRC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103669776 (SRC)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
umr04131
]
103669776 (SRC)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103669776 (SRC)
Protein kinases [BR:
umr01001
]
Non-receptor tyrosine kinases
SRC family
103669776 (SRC)
Membrane trafficking [BR:
umr04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
103669776 (SRC)
Endocytosis
Clathrin-mediated endocytosis
Kinases
103669776 (SRC)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
103669776 (SRC)
Macropinocytosis
Kinases
103669776 (SRC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
SH3_3
Motif
Other DBs
NCBI-GeneID:
103669776
NCBI-ProteinID:
XP_008696339
UniProt:
A0A384CND9
LinkDB
All DBs
Position
Un
AA seq
536 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGD
WWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRES
ETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGL
CHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTL
KPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKY
LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYT
ARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER
GYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1611 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagccc
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctctgctgatggccaccgaggccctagtacggccttcccctccgcagctgccgag
cccaagctgttcgggggcttcaactcgtcagacacagtcacctccccacagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacagagggtgac
tggtggctggcccactcgctcagcacgggacagacgggttacatccctagcaactatgtg
gcaccctccgactctatccaggccgaggagtggtactttggcaagatcaccagacgggag
tcggaacggttactgctcaatgcggagaacccgagagggaccttcctagtgcgagaaagt
gagaccacgaaaggtgcctactgcctctccgtgtctgatttcgacaacgccaagggcctc
aacgtgaagcactacaagatccgcaagctggacagcggcggcttctacatcacgtcccgc
acccagttcaacagtctgcagcagctggtggcctactactccaaacatgctgacggtctg
tgccaccgcctcaccactgtgtgccctacgtccaagccccagactcagggcctggccaag
gatgcctgggagatccctcgggagtccctgcggctggaggtcaagctgggccaaggctgt
ttcggagaggtgtggatggggacctggaatggaaccaccagggtggccatcaaaaccctg
aagccaggcacgatgtctccggaggccttcctgcaggaggcccaggtcatgaagaaactg
aggcacgagaagctggtgcagctgtatgcggtggtgtctgaggaacctatctacatcgtc
acggagtacatgagcaaggggagtctgctggactttctcaagggggagacgggcaagtac
ctgcggctgcctcagctggtggacatggctgctcagatcgcctcaggcatggcctacgtg
gaacggatgaactatgtccaccgggacctccgtgctgccaacatcctggttggagagaac
ctcgtgtgcaaagtggctgactttgggctggctcggctcatcgaagacaatgagtacacg
gcccggcaaggtgccaaattccccatcaagtggacagctcccgaagcggccctctacggc
cggttcaccatcaagtcagatgtatggtcctttgggatcctgctgacggagctcacaaca
aagggacgggtgccctaccctgggatggtcaaccgtgaggtgctggaccaggtggagcgg
ggctaccgaatgccctgcccgcccgagtgtcccgagtccctgcacgacctcatgtgccag
tgctggcggaaggagccggaggagcggcccaccttcgagtacctgcaggccttcctggaa
gactacttcacgtccaccgagccccagtaccagcctggagagaacctatag
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