KEGG   Ursus maritimus (polar bear): 103671685
Entry
103671685         CDS       T03271                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00230  Purine metabolism
umr01100  Metabolic pathways
umr01522  Endocrine resistance
umr04015  Rap1 signaling pathway
umr04020  Calcium signaling pathway
umr04022  cGMP-PKG signaling pathway
umr04024  cAMP signaling pathway
umr04062  Chemokine signaling pathway
umr04072  Phospholipase D signaling pathway
umr04114  Oocyte meiosis
umr04211  Longevity regulating pathway
umr04213  Longevity regulating pathway - multiple species
umr04261  Adrenergic signaling in cardiomyocytes
umr04270  Vascular smooth muscle contraction
umr04371  Apelin signaling pathway
umr04540  Gap junction
umr04611  Platelet activation
umr04713  Circadian entrainment
umr04714  Thermogenesis
umr04723  Retrograde endocannabinoid signaling
umr04724  Glutamatergic synapse
umr04725  Cholinergic synapse
umr04727  GABAergic synapse
umr04740  Olfactory transduction
umr04750  Inflammatory mediator regulation of TRP channels
umr04911  Insulin secretion
umr04912  GnRH signaling pathway
umr04913  Ovarian steroidogenesis
umr04914  Progesterone-mediated oocyte maturation
umr04915  Estrogen signaling pathway
umr04916  Melanogenesis
umr04918  Thyroid hormone synthesis
umr04921  Oxytocin signaling pathway
umr04923  Regulation of lipolysis in adipocytes
umr04925  Aldosterone synthesis and secretion
umr04926  Relaxin signaling pathway
umr04927  Cortisol synthesis and secretion
umr04928  Parathyroid hormone synthesis, secretion and action
umr04934  Cushing syndrome
umr04935  Growth hormone synthesis, secretion and action
umr04962  Vasopressin-regulated water reabsorption
umr04970  Salivary secretion
umr04971  Gastric acid secretion
umr04972  Pancreatic secretion
umr04976  Bile secretion
umr05032  Morphine addiction
umr05163  Human cytomegalovirus infection
umr05166  Human T-cell leukemia virus 1 infection
umr05200  Pathways in cancer
umr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    103671685 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    103671685 (ADCY3)
   04371 Apelin signaling pathway
    103671685 (ADCY3)
   04020 Calcium signaling pathway
    103671685 (ADCY3)
   04072 Phospholipase D signaling pathway
    103671685 (ADCY3)
   04024 cAMP signaling pathway
    103671685 (ADCY3)
   04022 cGMP-PKG signaling pathway
    103671685 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    103671685 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    103671685 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103671685 (ADCY3)
   04062 Chemokine signaling pathway
    103671685 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    103671685 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    103671685 (ADCY3)
   04912 GnRH signaling pathway
    103671685 (ADCY3)
   04913 Ovarian steroidogenesis
    103671685 (ADCY3)
   04915 Estrogen signaling pathway
    103671685 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    103671685 (ADCY3)
   04921 Oxytocin signaling pathway
    103671685 (ADCY3)
   04926 Relaxin signaling pathway
    103671685 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    103671685 (ADCY3)
   04918 Thyroid hormone synthesis
    103671685 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    103671685 (ADCY3)
   04916 Melanogenesis
    103671685 (ADCY3)
   04925 Aldosterone synthesis and secretion
    103671685 (ADCY3)
   04927 Cortisol synthesis and secretion
    103671685 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103671685 (ADCY3)
   04270 Vascular smooth muscle contraction
    103671685 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    103671685 (ADCY3)
   04971 Gastric acid secretion
    103671685 (ADCY3)
   04972 Pancreatic secretion
    103671685 (ADCY3)
   04976 Bile secretion
    103671685 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    103671685 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    103671685 (ADCY3)
   04727 GABAergic synapse
    103671685 (ADCY3)
   04725 Cholinergic synapse
    103671685 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    103671685 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    103671685 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    103671685 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    103671685 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    103671685 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    103671685 (ADCY3)
   04714 Thermogenesis
    103671685 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103671685 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    103671685 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    103671685 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    103671685 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103671685 (ADCY3)
   05163 Human cytomegalovirus infection
    103671685 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    103671685 (ADCY3)
Enzymes [BR:umr01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     103671685 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N NCE101 fn3_4
Other DBs
NCBI-GeneID: 103671685
NCBI-ProteinID: XP_008698591
UniProt: A0A384CUW6
LinkDB
Position
Un
AA seq 1134 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCTVVFSSDKLAPLLVAGMGLLLDIL
LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFARAHSASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGMHLLREILANVSLYLCAVAVG
VMSYYMADRKHRKAFLEAREEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNT
MYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDC
YYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKR
WQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCEYLDEKGIET
YLIIASKPEVKKTAAQHGLGGRVSPPPAPDRPREGAVSENQELPGQAHAXGSTSEEPEEQ
ETQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLL
SMRFMDPDMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYMTFVVGEVLL
LILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYY
TGPTNSTAGLEVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVTGAVAVIN
IYAWRPIFDEYDRKRFQEHDFPAVALEKMQGFSTPGLNGTGRLPLVPSKYSMTAMILVMM
LSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKR
DEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRV
ITKIKTIGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADFALAMKDTLTNI
NNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQ
AILREYGFRFVRRGTIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQVVDNS
NT seq 3405 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctccgagcctgagtactcggccgagtactccgccgagtac
tcggtcagcctgccctctgaccctgaccgcggggtgggccggacccatgaaatctcggtc
cggaactcgggatcctgcctctgcctgcctcggttcatgcggctgaccttcgtgcccgag
tccttggagaacctgtaccagacctacttcaaacggcagcgccatgagaccctgctggtg
ctggtggtgttcgctgcgctcttcgactgctatgtggtggtcatgtgcacggtggtcttc
tccagcgacaagctggctcccctcctcgtagctgggatgggactgctgttggacatcctc
ctcttcgtactctgcaaaaaggggctgctcccggaccgggtcacccggaaagtggtgccc
tacctgctgtggctactgataactgcccagattttctcttacctgggcctgaactttgcc
cgagcccactcggccagtgacacggtgggctggcaggccttctttgtcttctccttcttc
atcacgctgccgctcagcctcagccccatcgtcatcatctctgtggtctcctgcgttgtg
cacacactcgtcttgggggtcaccgtggcccagcagcagcaggacgggctgaagggcatg
cacttgctgagggagatcctggcgaacgtctccctctacctgtgcgccgtcgccgtgggc
gtcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgcgag
gagcagagccagcagcaggagaaccttatgctctccatcctgcccaagcacgtggctgac
gagatgctgaaggacatgaagaaggacgagagccagaaggaccagcagcagttcaacacc
atgtacatgtaccggcacgagaacgtcagcatcctctttgcggacatcgtgggcttcacc
cagctgtcttctgcctgcagtgcccaggagctcgtgaagctgctcaacgagctctttgcc
cgcttcgacaagctggcagccaaataccaccagctgcggattaagatcctaggcgactgt
tactactgcatctgcggcctgcccgactaccgggaggaccacgccgtctgctccatcctc
atggggctcgccatggtggaggccatctcgtacgtgcgggagaagacgaagactggggtg
gacatgcgcgtgggggtgcacacgggcaccgtgctggggggcgtcctgggccagaaacgc
tggcagtacgacgtgtggtctaccgacgtcactgtggccaacaagatggaggccggaggc
atccccgggcgtgtgcacatctcccagagcaccctggactgcctgaagggcgagttcgat
gtggagccgggcgacgggggcagccgctgtgagtacctggacgagaagggcatcgagacc
tacctcatcatcgcgtccaagccagaggtgaagaagacagccgcccagcacggcctcggt
ggccgggtgagtcccccgcccgccccggacaggccacgggaaggggctgtctcagaaaat
caggaactgccaggccaggcccacgcnnncggctccacatcggaggagcccgaggagcag
gagacccaggccgacaacccctcgttccccaacccgcgccggaggctgcgccttcaggac
ctggctgaccgagtggtggacgcctccgaggatgagcacgagctcaaccagctactcaac
gaggccctgctggagcgagagtccgcccaggtggtgaagaagagaaacaccttcctcctt
tccatgcggttcatggaccccgacatggaaacccgctactcagtggagaaggaaaagcag
agcggggctgccttcagctgctcctgcgtcgtcctgctctgtacggccctggtcgagata
ctcatcgacccctggctaatgacaaactacatgacctttgtggttggggaggttctgctt
ctgatcctgacaatctgctcgctggccgccatctttccccgggcctttcctaagaagctc
gtggccttctccacttggatcgaccggacccgctgggccaggaacacctgggccatgtta
gccatcttcattctggttatggcaaatgtcgtggacatgctcagctgtctccagtactac
acaggcccaaccaacagcactgcagggctggaggtggaagacggctgcgtcgagaacccc
aagtattacaactatgtcgccgtgctgtccctcatcgccaccatcatgctggtgcaggtc
agccacatggtgaagctcacactcatgctgctcgtcaccggggctgtggccgtcatcaac
atctatgcctggcgccccatctttgatgaatacgaccgcaaacgttttcaggaacatgac
ttccctgcagtcgccttagagaagatgcagggattttccacccctgggctcaatggcacc
ggcaggctgcccctggtaccttctaagtactccatgaccgcgatgatcctcgtcatgatg
ctgagcttctactacttctcacgccacgtggaaaaattggcaaggacactgttcttgtgg
aagattgaggtccatgaccagaaggaacgggtctacgagatgcggcgctggaacgaggcc
ttggtcaccaacatgttgcctgagcacgtggcacgccatttcctggggtccaagaagaga
gatgaggagctgtacagccagtcttacgatgagatcggagtcatgtttgcctccctgccc
aacttcgccgacttctacacggaggagagcatcaacaacggcggcattgagtgtctgcgc
ttcctcaacgagatcatctccgactttgattctctcctggacaatcccaagttccgggtc
atcaccaagatcaaaaccattggcagcacctacatggccgcttccggagtcaccccagat
gtcaacaccaacggctttgccagctccaacaaggaggagaagtcagacaaggagcgctgg
cagcacctggctgatctggccgacttcgctctggccatgaaggatacgctcacaaacatc
aacaaccagtccttcaacaacttcatgctgcgcatcggcatgaacaaaggaggggtcctg
gctggggtcattggagcccggaaaccacactatgacatctggggcaacacagtcaatgtg
gccagcaggatggagtccacaggggtcatgggcaacattcaggtggtggaagaaacacaa
gccatccttcgagagtacggcttccgctttgtgaggcgagggacaatctttgtgaaaggg
aaaggggagctgctaacctttttcttgaaggggcgtgataagccagctgccttcccaaat
ggctcctcggtcaccctgccccaccaggtggtggacaactcctga

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