Ursus maritimus (polar bear): 103672987
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Entry
103672987 CDS
T03271
Symbol
BTK
Name
(RefSeq) tyrosine-protein kinase BTK isoform X2
KO
K07370
Bruton agammaglobulinemia tyrosine kinase [EC:
2.7.10.2
]
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr04064
NF-kappa B signaling pathway
umr04380
Osteoclast differentiation
umr04611
Platelet activation
umr04662
B cell receptor signaling pathway
umr04664
Fc epsilon RI signaling pathway
umr05169
Epstein-Barr virus infection
umr05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
103672987 (BTK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
103672987 (BTK)
04662 B cell receptor signaling pathway
103672987 (BTK)
04664 Fc epsilon RI signaling pathway
103672987 (BTK)
09158 Development and regeneration
04380 Osteoclast differentiation
103672987 (BTK)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
103672987 (BTK)
09163 Immune disease
05340 Primary immunodeficiency
103672987 (BTK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
umr01001
]
103672987 (BTK)
Enzymes [BR:
umr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103672987 (BTK)
Protein kinases [BR:
umr01001
]
Non-receptor tyrosine kinases
TEC family
103672987 (BTK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
PH
BTK
SH3_9
SH3_2
Kinase-like
SH3_3
SH3_10
ABC1
Pkinase_fungal
Kdo
Haspin_kinase
SH3_4
DNApol3-delta_C
Motif
Other DBs
NCBI-GeneID:
103672987
NCBI-ProteinID:
XP_008699918
UniProt:
A0A384CYK1
LinkDB
All DBs
Position
X
AA seq
659 aa
AA seq
DB search
MATVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEK
ITCVETVVPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEEL
RKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSS
HRKTKKPLPPTPEEDQILKKPLPPEPTAAPVSASELKKVVALYDYMPMNANDLQLRKGDE
YFILEESNLPWWRARDKNGQEGYIPSNYVTEAEDSIEMYEWYSKHMTRSQAEQLLKQEGK
EGGFIVRDSSKAGKYTVSVFAKSTGDPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELIN
YHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGK
WRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANG
CLLNYLREMRNRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDF
GLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYER
FTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKAEERPTFKILLSNILDVMDEES
NT seq
1980 nt
NT seq
+upstream
nt +downstream
nt
atggctacagtaatcctggagagcatctttctgaagcgatcccagcagaaaaaaaagaca
tcgcctttaaacttcaagaagcgcctctttctcttgactgtgcacaaactttcctactat
gagtatgactttgaacgtgggagaagaggcagtaagaagggttcaatagacgttgagaag
atcacctgcgttgaaacagtggttcctgaaaaaaatcctccccctgaaagacagattcca
agaaggggtgaagagtccagtgaaatggagcagatttcaatcattgaaaggttcccttac
cccttccaggttgtgtatgacgaagggcctctttatgtcttctccccaactgaagaactg
aggaagcgttggattcaccagctcaaaaatgtaatccggtacaacagtgacctggtacag
aaataccacccttgcttctggatcgatgggcagtatctctgctgctctcagacagccaaa
aatgcgatgggctgccaaattctggagaacaggaatggaagtttaaaacctgggagttct
cacagaaagacaaaaaagccccttcctcccacacccgaggaggaccagatcttgaaaaag
ccactgccccctgagccaacagcagcacctgtctctgcaagtgagctgaaaaaggttgta
gccctttatgattacatgccaatgaacgcaaatgatctacagctacgaaagggtgacgag
tattttatcctggaggagagcaacttaccctggtggagagcgcgggataaaaatgggcag
gaaggctacatccctagtaactatgtcaccgaagcagaagactctatagaaatgtatgag
tggtattccaaacacatgacccggagtcaggctgagcaactgctcaagcaagaggggaaa
gaaggaggtttcattgtcagagactccagcaaagctggaaaatatactgtgtccgtgttt
gctaaatctacaggggaccctcaaggggtgatacgccattatgttgtgtgttccacaccg
cagagccagtattacctggcagagaagcatcttttcagcaccatccctgagctcatcaac
taccatcagcataactctgcagggctcatatctaggctcaaatatccagtgtctcaacaa
aacaagaatgcaccttccactgcgggcctgggctatggatcatgggaaattgatccaaag
gacctgaccttcttgaaggagctggggactggacagtttggggtagtgaagtatgggaaa
tggagaggccagtacgatgtggccatcaagatgatcaaagaaggctccatgtccgaggat
gagttcattgaagaagccaaagtcatgatgaatctgtcccatgagaagctggtacagttg
tacggcgtctgcaccaaacagcgccccatcttcatcatcactgagtacatggccaatggc
tgcctcctgaactacctgagggaaatgcgcaaccgcttccagacccagcagctgttggag
atgtgcaaggatgtctgcgaggccatggaatacctggagtcaaagcaattccttcaccga
gacctggcggctcgaaactgtttggtaaatgatcaaggagttgttaaagtatctgacttc
ggcctctccaggtatgtcctggatgatgaatatacaagctcagtaggctccaaatttcca
gtccggtggtctccaccagaagtccttatgtatagcaagttcagcagcaaatctgacatc
tgggcttttggggttttgatgtgggaaatttactctctggggaagatgccttatgaaaga
tttactaacagtgaaaccgctgaacacattgcccaaggcctacgtctctataggcctcat
ctagcttcagagagggtatataccatcatgtacagctgctggcatgagaaagcagaggaa
cgccccactttcaaaattcttctgagcaacatcctagatgtcatggatgaagaatcctga
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