Ursus maritimus (polar bear): 103675283
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Entry
103675283 CDS
T03271
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1
KO
K02599
Notch 1
Organism
umr
Ursus maritimus (polar bear)
Pathway
umr01522
Endocrine resistance
umr04330
Notch signaling pathway
umr04658
Th1 and Th2 cell differentiation
umr04919
Thyroid hormone signaling pathway
umr05020
Prion disease
umr05165
Human papillomavirus infection
umr05200
Pathways in cancer
umr05206
MicroRNAs in cancer
umr05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
umr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
103675283 (NOTCH1)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
103675283 (NOTCH1)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
103675283 (NOTCH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103675283 (NOTCH1)
05206 MicroRNAs in cancer
103675283 (NOTCH1)
09162 Cancer: specific types
05224 Breast cancer
103675283 (NOTCH1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
103675283 (NOTCH1)
09164 Neurodegenerative disease
05020 Prion disease
103675283 (NOTCH1)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
103675283 (NOTCH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_4
Ank_5
Ank_3
EGF_3
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
103675283
NCBI-ProteinID:
XP_040488144
UniProt:
A0A8M1G7L0
LinkDB
All DBs
Position
Unknown
AA seq
2553 aa
AA seq
DB search
MPPLLAPLLCLALLPALAARGLRCSQPSDSCLNGGKCEVFPNGTEACICSGAFVGQRCQA
PNPCLSAPCKNAGTCHTVDRGGLVDYACTCRLGFSGPLCLNACLSTPCRNGGTCDLLTLT
EYKCRCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPPGFHGPTCRQDVNECS
QNPRLCQNGGTCHNEVGSYRCTCRATHTGRDCELPYVPCSPSPCQNGGTCRPTGDTTHEC
ACLPGFTGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMP
NACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPH
GRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPC
EHAGKCINTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYE
GVHCEVNTDECASSPCLQNGRCLDKINEFLCECPTGFTGHLCQYDVDECASTPCKNGAKC
LDGPNTYTCVCTEGYTGPHCEVDINECDPDPCHYGVCKDGVATFTCLCRPGYTGHHCESN
INECHSQPCRHGGTCQDRDNAYLCSCLKGTTGPNCETNLDDCASSPCDSGTCLDKIDGYE
CACEPGYTGSMCNVNIDECAGNPCHHGGTCEDGINSFTCHCPEGYHGPTCLSEVNECSSN
PCIHGACRDSLNGYKCDCDPGWSGANCDVNNNECESNPCANGGACRDMTSGYVCTCREGF
SGPNCQTNINECASNPCLNQGSCIDDVAGYKCNCPLPYTGATCEVVLAPCAPGPCRNGGA
CKESEDYESFSCICPTGWQGQTCEVDVNECVKSPCHHGASCQNTNGGYRCHCHAGYTGHD
CETDVDDCRPNPCHNGGSCTDGVNTAFCDCLPGFQGAFCEEDINECASNPCRHGANCTDC
VDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDIN
ECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNTLYRC
ECHSGWTGLYCDVPNVSCEVAAQRQDINVTHLCRNGGLCMDAGNTHHCRCQAGYTGSYCE
DQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEINECLSQPCQNGGTCIDLTN
TYKCSCPRGTQGVHCEVNVDDCSPPIDPVSRGPKCFNNGTCVDQVGGYSCACPPGFVGER
CEGDVNECLSNPCDARGTQNCVQRVNDFYCECRAGHTGRRCESVINGCKGRPCQNGGTCA
VASNTARGFICKCPAGFEGATCENDARACGSRHCLNGGTCISGPRSPTCLCLGPFTGPEC
QFPAGSPCVGGNPCYNQGSCEPTAESPFYRCLCPAKFNGLLCHILDYSFGGGLGLDIPPP
QIEEACELPECREEAGNKVCSLACNNHACGWDGGDCSLNFNDPWQNCSQSLQCWKYFSNG
RCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFGDGHCDQGCNSAECEWDGLDCAE
HVPERLAAGALVLVVLTPPAQLRNNSLHFLRELSRLLHTNVVFKRDAHGQPMIFPYYGHE
EELRKHPIKRAVDGWAAPGALLDRVEAALLPGGGAGRRRRELDPMDVRGSIVYLEIDNRQ
CVQSSSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPQLHFMYVAVAAF
VLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGA
LMDDNQNEWGDEDLEAKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRVSAMAPTPPQ
GEADADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQT
DRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNR
ATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVEAA
VVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER
MHHDIVRLLDEYSLVRSPQLHGTALGGAPTLSPPLCSPNGYLGNLKPAVPGKKARKPSTK
GLACGGKEAKDLKARRKKSQDGKGCLLDSSSVLSPVDSLESPHGYLSDVASPPLLSSPFQ
QSPSVPLGHLPGMPDAHLGVGHLSVAAKPEMAALGAGGRLAFEAGPPRLSHLPVASSTGA
VLGTASGGGGGGAVNFTVGGAAGLNGQCEWLSRLQNGLVPNQYNPLRGSVASGPLGTQAP
ALQHGMMGPLHAGLSTTAALSQAMSYQALPSTRLAGQPHLLQTQPLPQVQQPPQNLQMQP
PGVPQPQSLQPPPPHLGVSSAAGGHMGRSFLGGEPSQADVQPLGPSSLAVHTLLPPDSQA
LPTALPATLAPPMTTAQFLTPPSQHSYSSSPADNTPSHQLQVPEHPFLTPSPESPDQWSS
SSPHSHVSDWSEGISSPPTSTQSHIAHIPEALK
NT seq
7662 nt
NT seq
+upstream
nt +downstream
nt
atgccgccgctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgcacga
ggcctgcgatgttcccagcccagtgacagctgcttgaatggcgggaagtgtgaagtgttc
cccaacggcaccgaagcctgcatctgcagcggggccttcgtgggccagcggtgccaggcg
cccaacccctgcctcagcgccccctgcaagaacgccgggacgtgccacaccgtggaccgt
ggtggcttggtggactacgcctgcacctgccggctgggcttctctgggcccctctgcctg
aacgcctgcctctccaccccctgccgcaacgggggcacctgtgacctgctcacgctcacc
gagtacaagtgccgctgtcccccaggctggtcagggaagacgtgccagcaggccgacccg
tgcgcctccaacccctgtgccaatggcggccagtgcctgccctttgaggcctcgtacatc
tgtggctgcccgcccggcttccacggccccacctgccggcaggacgtgaacgagtgcagc
cagaaccccaggctctgccagaacgggggcacctgccacaacgaggtcggctcctaccgc
tgcacctgccgtgccacccacaccggccgcgactgcgagctgccctacgtgccctgcagc
ccctccccctgccagaacgggggcacctgccgccccacgggggacaccacccacgagtgc
gcctgcctgccaggcttcaccggccagaactgtgaggagaacgtcgacgactgtcccgga
aacaactgcaagaacggaggcgcctgcgtggacggcgtgaacacctacaactgccgctgc
ccgccagagtggacaggtcagtactgcaccgaggacgtggacgagtgtcagctcatgccc
aacgcctgccagaacggcgggacctgccacaacacccacggcggctataactgcgtatgc
gtcaacggctggacgggcgaggactgcagcgagaacatcgatgactgcgccagtgccgcc
tgctttcacggtgccacctgccatgaccgcgtggcctccttctactgcgagtgtccccac
ggccgcacgggtctgctgtgccacttgaatgacgcctgcatcagcaacccttgcaacgag
ggctccaactgtgacaccaaccccgtgaacggcaaagccatttgcacctgcccctcgggg
tacacggggccggcctgcagtcaggacgtggacgagtgctcgctgggcgccaacccctgt
gagcacgcgggcaagtgcatcaacacgctgggctccttcgagtgccagtgtctgcagggc
tacaccggcccccgctgcgagatcgacgtcaatgagtgcatctcgaacccgtgtcagaat
gacgccacctgcctggatcagatcggggagttccagtgcatctgcatgcctggctacgag
ggcgtgcactgtgaggtcaacacggacgagtgtgccagcagcccctgtctccagaatggc
cgctgcctggacaaaatcaacgaatttctgtgcgagtgccccacaggtttcaccgggcat
ctgtgtcagtatgacgtggacgagtgtgccagcacgccctgcaagaatggcgccaagtgc
ctggacgggcccaacacatacacctgcgtgtgcacagaaggctacacggggccgcactgc
gaggtggacatcaacgagtgtgaccccgacccgtgccactacggggtgtgcaaggatggg
gtggccaccttcacctgcctgtgccggccgggctacacaggccaccactgcgagagcaat
attaacgagtgccacagccagccctgccgccacggcggcacctgccaggaccgcgacaat
gcctacctctgctcctgcctcaaggggaccacaggacccaactgtgagacgaacttggat
gactgcgccagcagcccctgcgactcgggcacgtgcctggacaagatcgatggctacgag
tgtgcgtgcgagcccggctacacagggagcatgtgcaacgtgaacatcgacgagtgcgcg
ggcaacccctgccaccacgggggcacctgtgaggacggcatcaacagcttcacgtgccac
tgccccgagggctaccacggccccacctgcctgtccgaggtcaacgagtgcagcagcaac
ccctgtatccatggggcctgccgggacagcctcaacgggtacaagtgtgactgtgacccc
gggtggagcggcgccaactgtgacgtgaacaacaacgagtgtgagtccaacccgtgtgcc
aacggtggcgcctgcagggacatgaccagcggctacgtgtgcacctgccgcgagggcttc
agtggccccaactgccaaaccaacatcaacgagtgtgcgtccaacccgtgcctgaaccag
ggctcgtgcatcgatgatgtggccgggtacaagtgcaactgtccgctgccctacacagga
gccacatgtgaggtggtgctggccccgtgtgcccccggcccctgcagaaacgggggcgcg
tgcaaggagtcagaggactatgagagtttctcctgcatctgccccacgggctggcaagga
cagacctgcgaggtggacgttaacgagtgtgtgaagagcccgtgccaccacggcgcctcc
tgtcagaacaccaacggtggctaccgctgccactgtcacgcgggctacacgggccacgac
tgcgagacggacgtggacgactgccggccgaacccgtgccacaacggcggctcctgcacc
gacggcgtcaacacggctttctgcgactgcctgcccggcttccagggggccttctgcgag
gaggacatcaacgagtgcgccagcaacccatgccgccacggcgccaactgcacggactgc
gtggacagctacacgtgcacctgccccgcgggcttcagcgggatccactgcgagaacaac
acgcccgactgcacagagagctcctgcttcaatggcggcacctgtgtggacggtatcaac
tccttcacctgcctgtgtccgccgggcttcacgggcagctactgccagcatgacatcaac
gagtgcgactcgcggccctgcctgcatggtggcacctgccaggacagctatgggacgtac
aagtgcacctgtccgcagggctacacaggcctcaactgccagaatctcgtgcgctggtgc
gactcctcaccctgcaagaatggcggcaagtgctggcagaccaacaccctgtaccgctgt
gagtgccacagcggctggaccggcctctactgcgacgtgcccaacgtgtcctgcgaggtg
gccgctcagcggcaagacatcaacgtcacccacctgtgccggaacggggggctctgcatg
gacgcgggcaacacccaccattgccgctgccaggcgggttacacaggcagctactgcgag
gaccaggtggacgagtgctcgcccagcccctgccagaacggggccacctgcaccgactac
ccgggcggctactcctgtgagtgtgtggccgggtaccacggggtgaactgctccgaggag
attaacgagtgtctgtcccagccatgccagaatgggggtacctgcatcgacctcaccaat
acctacaagtgctcctgtccccggggcacacagggcgtgcactgtgaggtcaacgtggac
gactgcagtccccccatcgaccccgtctcccggggccccaagtgctttaataacggcacc
tgcgtggaccaggtgggcggctacagctgcgcctgcccgcccggcttcgtcggggagcgc
tgtgagggcgacgtgaacgagtgcctgtccaacccctgtgatgcccgtggcacccagaac
tgtgtgcagcgcgtcaatgacttctactgcgagtgccgcgcgggccacactggacgccgc
tgtgagtcggtcatcaacggctgcaagggcaggccctgccagaatgggggcacttgcgct
gtggcctccaacaccgcccgcgggttcatctgcaaatgtcccgcgggctttgagggcgcc
acctgcgagaacgacgcgcgggcctgcgggagccggcactgcctcaatggcggcacgtgc
atctcgggcccgcgcagccccacgtgcctgtgcctgggccccttcaccggcccggagtgc
cagttccctgccggcagcccctgcgtgggcgggaacccctgctacaaccagggcagctgc
gagcccacggcggagagccccttctaccgctgcctgtgccccgccaagttcaacgggctc
ctgtgccacatcctggactacagtttcgggggcggcctgggcctcgacatccctcctccg
cagatcgaggaggcgtgcgagctgcctgagtgccgggaggaggcaggcaacaaggtgtgc
agcctggcctgcaacaaccacgcgtgcggctgggacggcggcgactgctcgctcaacttc
aacgacccctggcagaactgctcgcagtcgctgcagtgctggaagtacttcagcaacggc
cgctgcgacagccagtgcaactccgccggctgcctgttcgatggcttcgactgccagcgc
gcggagggccagtgcaaccccctgtacgaccagtactgcaaggaccactttggcgacggg
cactgcgaccagggctgcaacagcgccgagtgcgagtgggacgggctggactgcgcagag
cacgtgcccgagcggctggcggccggcgcgctggtgctggtggtgctgacaccccccgca
cagctccgcaacaactccctgcattttctgcgggagctcagccgcctgctgcacaccaac
gtggtgttcaaacgcgacgcgcacggccagcccatgatcttcccgtactacggccacgag
gaggagctgcgcaaacaccccatcaagcgcgcggtggacggctgggccgcgcctggggcc
ctgctggaccgggtggaggccgccctgctcccgggtggtggggccggccgccggcgcagg
gagctggaccccatggacgtccgcggatccatcgtctacctggaaattgacaaccggcag
tgtgtccagtcgtcctcacaatgtttccagagcgccacggacgtggctgccttcctgggt
gcactcgcctcgctggggagcctcaacatcccttataagatcgaggccgtgcagagtgag
accgtggagccacccccgcccccgcagctgcacttcatgtacgtggccgtggccgccttt
gtgctgctcttcttcgtgggctgcggggtgctgttgtcccgcaagcgccggcggcagcat
ggacagctctggttccccgaaggcttcaaggtgtcagaggccagcaagaagaagcggcgg
gagcccctcggcgaggactccgtgggcctcaagcccctgaagaacgcctcagacggcgct
ctcatggatgataaccagaatgagtggggtgacgaggacctggaggccaagaagttccgg
ttcgaagagccggtggttcttcctgacctggacgaccagacagaccaccggcagtggacc
cagcagcacctggacgctgccgacctgcgcgtgtcggccatggcccccacaccgccccag
ggcgaagcggacgctgactgcatggacgtcaatgtccgagggccagatggcttcacaccc
ctcatgatcgcgtcctgcagcggagggggcctggagacgggcaacagcgaggaggaggag
gacgcgccggctgtcatctcggacttcatctaccagggggccagcctgcacaaccagacg
gaccgcactggcgagaccgccctgcacctggctgcccgctactcgcgctccgatgcagcc
aagcgcctgctggaagccagcgcagatgccaacatccaggacaacatgggacgtaccccg
ctgcacgcggccgtgtctgccgatgcacagggagtcttccagattctcatccggaaccga
gccacggacctggacgcccgcatgcatgacggcacgacgccgctgatcctggctgcccgc
ctggccgtcgagggcatgctggaagacctgatcaactcgcacgccgacgtcaatgccgtg
gatgacctgggcaagtctgccctgcactgggccgctgccgtgaataacgtggaggctgcc
gtcgtgctcctgaagaacggggccaacaaggacatgcagaacaacaaggaggagacaccc
ctgttcctggctgctcgggagggcagctacgagaccgccaaggtgctgctggaccacttt
gccaaccgggacatcacagaccacatggaccgcctaccccgcgacatcgcgcaggagcga
atgcaccacgacatcgtgcggctgctggacgagtacagcctagtgcgcagcccccagctg
cacggcaccgccctgggcggcgcgcctaccctgtccccaccgctctgctcgcccaacggc
tacctgggcaacctcaagccggccgtgccaggcaagaaggcccgcaagcccagcaccaag
ggcctggcctgtggcggcaaggaggccaaggacctcaaggcacgcaggaagaaatcccag
gacggcaagggctgcctgctggacagctcgagcgtgctgtcacccgtggactcccttgag
tcgccccacggctacctgtcggacgtggcctcgccgcccctcctgtcctctccattccag
cagtccccgtccgtgcccctcggccacttgcccggcatgcctgacgcccacctgggtgtt
ggccacctgagcgtggctgccaagcccgagatggcagcgctgggtgcgggtggccggctg
gccttcgaggcggggccgccgcggctctcccacctgccggtggcctctagcaccggcgcc
gtcctgggcactgccagcggcgggggcggcgggggcgccgtgaatttcaccgtgggcggg
gccgcaggcctgaacggccagtgtgagtggctgtcccggctgcagaacggcctggtgccg
aaccagtacaacccactgcgagggagcgtggcgtcgggccccctgggcacacaggccccc
gccctgcagcacggcatgatgggcccgctgcacgccggcctctccaccacggcggcgctg
tcccaggcaatgagctaccaggccctgcccagcacgcgcctggccggccagccgcacctg
ctgcagacccagccgctgccccaggtgcagcagccgccgcagaacttacagatgcagccg
cccggcgtcccgcagccgcagagcctgcagccacccccgccgcacctcggcgtgagctcg
gccgccggcggccacatgggccggagcttcctgggcggggagccaagccaggccgacgtg
cagccgctgggccccagcagcctggccgtgcacaccctcctgccgccggacagccaggcc
ctgcccacggccctgcctgccacgctggccccgcccatgaccaccgctcagttcctgacc
ccgccctcgcagcacagctactcgtcctcgcccgcggacaacacccccagccaccagctc
caggtgcctgagcaccccttcctcaccccgtccccggagtccccggaccagtggtccagc
tcgtcgccgcattcccacgtctctgactggtctgagggcatctccagcccgcccaccagc
acgcagtcccacatcgcccacattccggaggcgctcaagtaa
DBGET
integrated database retrieval system
