Ursus maritimus (polar bear): 103678785 Help Entry 103678785         CDS       T03271                                  Gene name GSK3B Definition (RefSeq) glycogen synthase kinase 3 beta   KO K03083   glycogen synthase kinase 3 beta [EC:2.7.11.26] Organism umr  Ursus maritimus (polar bear) Pathway umr01521   EGFR tyrosine kinase inhibitor resistance umr04012   ErbB signaling pathway umr04062   Chemokine signaling pathway umr04110   Cell cycle umr04150   mTOR signaling pathway umr04151   PI3K-Akt signaling pathway umr04310   Wnt signaling pathway umr04340   Hedgehog signaling pathway umr04360   Axon guidance umr04390   Hippo signaling pathway umr04510   Focal adhesion umr04550   Signaling pathways regulating pluripotency of stem cells umr04657   IL-17 signaling pathway umr04660   T cell receptor signaling pathway umr04662   B cell receptor signaling pathway umr04722   Neurotrophin signaling pathway umr04728   Dopaminergic synapse umr04910   Insulin signaling pathway umr04916   Melanogenesis umr04917   Prolactin signaling pathway umr04919   Thyroid hormone signaling pathway umr04931   Insulin resistance umr04932   Non-alcoholic fatty liver disease umr04934   Cushing syndrome umr04935   Growth hormone synthesis, secretion and action umr05010   Alzheimer disease umr05020   Prion disease umr05022   Pathways of neurodegeneration - multiple diseases umr05135   Yersinia infection umr05160   Hepatitis C umr05162   Measles umr05163   Human cytomegalovirus infection umr05165   Human papillomavirus infection umr05167   Kaposi sarcoma-associated herpesvirus infection umr05200   Pathways in cancer umr05210   Colorectal cancer umr05213   Endometrial cancer umr05215   Prostate cancer umr05217   Basal cell carcinoma umr05224   Breast cancer umr05225   Hepatocellular carcinoma umr05226   Gastric cancer Brite KEGG Orthology (KO) [BR:umr00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     103678785 (GSK3B)    04310 Wnt signaling pathway     103678785 (GSK3B)    04340 Hedgehog signaling pathway     103678785 (GSK3B)    04390 Hippo signaling pathway     103678785 (GSK3B)    04151 PI3K-Akt signaling pathway     103678785 (GSK3B)    04150 mTOR signaling pathway     103678785 (GSK3B)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     103678785 (GSK3B)   09144 Cellular community - eukaryotes    04510 Focal adhesion     103678785 (GSK3B)    04550 Signaling pathways regulating pluripotency of stem cells     103678785 (GSK3B)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     103678785 (GSK3B)    04657 IL-17 signaling pathway     103678785 (GSK3B)    04662 B cell receptor signaling pathway     103678785 (GSK3B)    04062 Chemokine signaling pathway     103678785 (GSK3B)   09152 Endocrine system    04910 Insulin signaling pathway     103678785 (GSK3B)    04917 Prolactin signaling pathway     103678785 (GSK3B)    04935 Growth hormone synthesis, secretion and action     103678785 (GSK3B)    04919 Thyroid hormone signaling pathway     103678785 (GSK3B)    04916 Melanogenesis     103678785 (GSK3B)   09156 Nervous system    04728 Dopaminergic synapse     103678785 (GSK3B)    04722 Neurotrophin signaling pathway     103678785 (GSK3B)   09158 Development and regeneration    04360 Axon guidance     103678785 (GSK3B)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     103678785 (GSK3B)   09162 Cancer: specific types    05210 Colorectal cancer     103678785 (GSK3B)    05225 Hepatocellular carcinoma     103678785 (GSK3B)    05226 Gastric cancer     103678785 (GSK3B)    05217 Basal cell carcinoma     103678785 (GSK3B)    05215 Prostate cancer     103678785 (GSK3B)    05213 Endometrial cancer     103678785 (GSK3B)    05224 Breast cancer     103678785 (GSK3B)   09164 Neurodegenerative disease    05010 Alzheimer disease     103678785 (GSK3B)    05020 Prion disease     103678785 (GSK3B)    05022 Pathways of neurodegeneration - multiple diseases     103678785 (GSK3B)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     103678785 (GSK3B)    04931 Insulin resistance     103678785 (GSK3B)    04934 Cushing syndrome     103678785 (GSK3B)   09171 Infectious disease: bacterial    05135 Yersinia infection     103678785 (GSK3B)   09172 Infectious disease: viral    05160 Hepatitis C     103678785 (GSK3B)    05162 Measles     103678785 (GSK3B)    05163 Human cytomegalovirus infection     103678785 (GSK3B)    05167 Kaposi sarcoma-associated herpesvirus infection     103678785 (GSK3B)    05165 Human papillomavirus infection     103678785 (GSK3B)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     103678785 (GSK3B)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:umr01001]     103678785 (GSK3B)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:umr03036]     103678785 (GSK3B) Enzymes [BR:umr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.26  tau-protein kinase      103678785 (GSK3B) Protein kinases [BR:umr01001]  Serine/threonine kinases: CMGC group   GSK family [OT]    103678785 (GSK3B) Chromosome and associated proteins [BR:umr03036]  Eukaryotic type   Centrosome formation and ciliogenesis proteins    Kinases and associated factors     103678785 (GSK3B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kinase-like APH Kdo ABC1 Motif Other DBs NCBI-GeneID:  103678785 NCBI-ProteinID:  XP_008706415 UniProt:  A0A384DI01 LinkDB All DBs Position Un AA seq 433 aa AA seqDB search MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ TNNAASASASNST NT seq 1302 nt NT seq  +upstreamnt  +downstreamnt atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagtg gtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagacactaaa gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa ctggttgccatcaagaaagtattacaggacaagagatttaagaaccgagagctccaaatc atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatatgccaccgg gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg tactatagggcaccagagttgatctttggagccactgattatacctccagtatagatgta tggtctgcaggctgtgtgttggctgagctgttactaggacaaccaatatttccaggggac agtggtgtggatcaattggtggaaataatcaaggtcctggggacaccaacaagggagcaa attagagaaatgaaccccaactacacagaattcaaattccctcaaattaaggcacatcct tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc cggacgccaccggaggcaattgcactgtgtagccgtctgctggagtatacaccaactgcc cgattgacaccactggaagcttgtgcacattcattttttgatgaattaagggacccaaat gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg tcaagtaatccacctctagctaccatccttattcctcctcatgctcggattcaagcagct gcttcaacccctacaaatgccacagcagcctcagatgctaatgccggagaccgtggacag accaacaatgccgcttctgcatcagcttccaactccacctga

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