Vulpes vulpes (red fox): 112909041 Help Entry 112909041         CDS       T05911                                  Gene name TSC2 Definition (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism vvp  Vulpes vulpes (red fox) Pathway vvp04072   Phospholipase D signaling pathway vvp04115   p53 signaling pathway vvp04140   Autophagy - animal vvp04150   mTOR signaling pathway vvp04151   PI3K-Akt signaling pathway vvp04152   AMPK signaling pathway vvp04211   Longevity regulating pathway vvp04218   Cellular senescence vvp04714   Thermogenesis vvp04910   Insulin signaling pathway vvp04919   Thyroid hormone signaling pathway vvp05163   Human cytomegalovirus infection vvp05165   Human papillomavirus infection vvp05168   Herpes simplex virus 1 infection vvp05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:vvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     112909041 (TSC2)    04151 PI3K-Akt signaling pathway     112909041 (TSC2)    04152 AMPK signaling pathway     112909041 (TSC2)    04150 mTOR signaling pathway     112909041 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     112909041 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     112909041 (TSC2)    04218 Cellular senescence     112909041 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     112909041 (TSC2)    04919 Thyroid hormone signaling pathway     112909041 (TSC2)   09149 Aging    04211 Longevity regulating pathway     112909041 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     112909041 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     112909041 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     112909041 (TSC2)    05163 Human cytomegalovirus infection     112909041 (TSC2)    05165 Human papillomavirus infection     112909041 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:vvp01009]     112909041 (TSC2) Protein phosphatases and associated proteins [BR:vvp01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      112909041 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Telomere_reg-2 Motif Other DBs NCBI-GeneID:  112909041 NCBI-ProteinID:  XP_025840515 UniProt:  A0A3Q7SFT1 LinkDB All DBs Position Unknown AA seq 1813 aa AA seqDB search MAKPTSKDSGLKEKFRILLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFRAIKDYPANEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVTWDI LLNIMERLLHQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIQNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAMRVYETLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGSEKKAS GPLSPPTGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQEVDWKVLKLVLSKLPESLRYK VLIFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGEQQGGPELSSDPGTHVRQAKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDTPASHLLGGPTSPGTQAALASKSDRASAGARFPAQEKTSLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS AKPPPPPRSNTVASFSSLYQSSCQGKLHRSISWADSAVVLEEGNSSETSLPVEPTELEDF EATLGTDRRYGRTEAYSRSSSSSSQEEKFPAEELAAGGIPIERAVSSEGARPSVELSFQP SQPLSKSSSSPELQTLQDILGDPGDKSDVGRLSPEAKARSQSGILDGAGASWSTPGEENQ GQGPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRVEQDAFRSRAGASNTEKVPG INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSS SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPL DYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY PSKWIARLRHIKRLRHRIREEAHYTNPSLPLMQMHPLGHPKAPAQAPAEPLPTYETGQRK RLISSVDDFTEFV NT seq 5442 nt NT seq  +upstreamnt  +downstreamnt atggccaagcctacgagcaaagactcaggcctgaaggagaagttcaggattctgttggga ctgggaacaccgaggccaaaccccaggtcagcagagggcaagcagaccgagttcatcatc acggcggacatcctgagagagctgagtgttgaatgcggcatcaacaatcgcatccgggtg atagggcagatctgcgaagttgcaaaaacgaagaaatttgaagagcatgcagtagaagca ctctggaaggccgttgcggacctgctgcagccggagcggccccccgaggcccggcatgcg gtgctggcgctgctgaaggccatcgtgcaggggcagggggaccgcctgggcgttctccgg gctctgttctttagggccatcaaggattaccccgctaatgaagacctccatgaaagactg gaagttttcaaggccctcacggacaatgggagacacatcacctacttggaagaagaactg gctgggtttgtcctgcagtggatggacatcggcctgtcctccgaattcctcctggtgctt gtgaacttggtcaagttcaacagctgttacctggatgagtacattgcatcaatggtccac atgatctgcctgctgtgcgtccagactgtgtcatccgtggacatagaggtctccctgcag gtgctggacgccgttgtctgctacaactgcctgccggccgagagcctccccctgttcatt gtcactctgtgccgcaccatcaatgtgaaggagctctgtgagccttgctggaagctgatg cggaacctgctgggcacccacctgggccacagtgccatctacaacatgtgtcgcatcatg gaggacagagcctacatggaagatgccccactgctgagaggggctgtgttctttgtgggg atggccctttggggagcacaccgactctactctctcaagaactccccaacgtctgtgttg ccgtcattttatgaggccatgacctgtccgaatgaggtggtgtcctatgaaatcgtcctc tctataaccagactcatcaagaagtaccggagggagctgcaagctgtgacctgggacatc ttactgaacatcatggagcgcctcctgcaccagctccagaccctggacagcccggagctc agaaccatcgtgcacgacctgctgaccacagtggaagagctgtgtgatcagaatgagttc cacggctctcaggagagatactttgagctggttgagcgatgtgcagaccagaggccggag tcttccctcttaaacttaataacgtaccgggctcagtcgatccacccggcgaaggacggc tggattcagaacctgcagttactgatggagaggttcttcaggaatgaatctcgcagtgct gtgcgcatcaaggtgctggacgtcctgtccttcgtgctgctcatcaacaggcagttctat gaggaggagctaatcagctcagtggtcatctcacagctctcccacgtcccggaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggctgaaggctgccac acccaccacttcaacagtctgttggacattgtggaaaaggtgattgcccgctctctctct ccaccccctgagctggaggaaagagacgtggcggcgtactcggcctccttagaggacgtg aagactgccgtcctggggctcctggtcatccttcagaccaagctgtacgccttgcctgcc agccatgcgatgcgtgtgtatgagacgctcgtcagccacatccagctccactacaagcat agctacaccctgcccatcgccagtagcatccggctgcaggcttttgacttcctactgctg ctgagggccgactcgctgcaccgccttggcctgcccagcaaggacggggccgtgaggttc agcccttactgcgtctgcgatgccatggagccagagagaggctcggagaagaaggccagt ggtcccctgtcacctcccacggggccgcctggtcctgcgcccgcaggccctgccgtgcgg cttggctccctgccctactccctgctcttccgtgtcctgctacagtgcctgaagcaggag gtggactggaaggtactgaagctcgtgcttagcaagctgccggagtccctgcgctataag gtgctcatcttcacctcaccctgcagtgtggaccagctgtcctccgccctctgctccatg ctctcaggtcccagaactctggagcggctccgaggcaccccggaagggttctccagaacc gacctgcacctggctgtggtccctgtgctgacggcgctcatctcttaccataactacctg gacaaaaccagacagcgggagatggtgtactgcctggagcaaggcctgatctaccgctgt gccagccagtgtgtggtggccctggccatctgcagcgtggagatgcctgacatcatcatc aaggcgcttcccgtcctggtcgtgaagctcacacacatctcggccacggccagtatggcc attcctctcctcgagttcctgtcaacgctggccaggctgccccacctgtacaggaacttc gcagcagagcagtacgcgagcgtgtttgccatctccctgccctacaccaatccctccaag ttcaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgc cgcctgcccttccggaaggattttgttccttatatcactaagggcctgcgctccaacgtt ctcctgtcttttgatgacacccccgagaaggacagtttcagagcacgaagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaagagagctctgccgccgaggccttccgatgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacaagcgccagcttg gggtctgccgacgagaactcgatggcccaggctgatgacaacttgaaaaatctccacctg gagctcacggaaacatgtctggacatgatggccagatacgtgttctccaacttcacagcg gtgcccaagaggtctccggtgggagagttcctcctggctggtggcaggaccaaaacctgg ctggttgggaacaagcttgttactgtgacgacgagcgtggggacggggacccggtcgctg ctgggcttggactcaggagagcagcaaggtggccccgagttgagctcggaccctggcacg catgtgagacaggcaaaggaggcacctgccaagctggagtcacaggctgggcagcaggtg tgccgcggcgcccgggaccgggtccgctccatgtccgggggccacggtcttcgtgttggt gccctggacactccagcctcccacttgctgggcggccccacttccccaggcacgcaggca gcgctggccagcaagtctgacagggcctcggctggtgcccggttcccagcacaggagaag acgagcctggcagcctacgtaccgctgctgacccagggctgggcggagatcttggtccgg aggcctacagggaacaccagctggctgatgagcctggagaacccgctcagccccttctcg tcggacatcaacaacatgcctctgcaggagctgtccaatgcgctcatggccgctgagcgc ttcaaggagcgtcgtgacacggctctgtacaagtccctgtcggtgcctgccgcaggctcg gccaagccccctccgcccccgagatctaacacggtggcctctttctcctccctgtaccag tccagttgccaaggaaagctgcacaggagcatttcctgggcagactctgcggtggttctg gaggagggaaattcaagcgagaccagtctgccagtggagcccacggagctggaggacttc gaggcgacactaggcacagaccggcgctatggccgcacggaagcttacagcaggtcgtct tcaagctccagccaggaggagaagttccctgcagaggagctggctgctggagggatcccc atcgaacgagccgtctcttctgagggcgcccggccttctgtggagctctccttccagccc tcccagcccctcagcaagtccagctcctcccctgagctgcagaccctgcaggatatactc ggggaccccggggacaagtctgatgttggccggctcagccctgaggccaaggcccggtca cagtccgggattctggacggggcgggtgcctcctggtccaccccaggtgaagagaaccag ggccagggccccgcacagcccgagggtcccttgccttccagctgcccccgctcccccagt ggcctgcggcccagaggctacaccatctctgattcagccccatcacgcagaggcaaaagg gtagagcaggacgccttcaggagcagagctggggcttccaacaccgagaaagtgccaggc atcaatcccagctttgtgttcctgcagctctaccactcacccttctttggtgacgagtcc aacaagcccattcttctacccaatgagtccttcgagcggtcagtgcagcttctcgaccag attccatcatacgacacacacaagatcgccgtcctgtatgtgggagaaggccagagcagc agtgagctcgccatcctgtccaacgagcatggctcatacaggtacacggagttcctgaca ggcctgggcaagctcatcgagctcaaagactgccagccggacaaggtgtacctggggggc ctggacgtgtgtggcgaagatggccagttcacctactgctggcatgacgacatcatgcaa gctgtcttccacattgccaccctgatgcccaccaaggatgtggacaagcaccgctgtgac aagaagcgccacctgggcaatgactttgtgtccatcgtctacaacgactctggtgaggac ttcaagctgggcaccatccgaggccagttcaacttcgtccacgtgatcatcacccccctg gactatgagtgcaacctggtgtccctgcagtgcaggaaagacatggaaggtcttgtggat accagcgtggccaagatcgtgtctgaccgcaacctgccttttgtggcacgtcagatggct ttgcacgcaaatatggcctcacaagtgcatcatagccgctccaaccccaccgacatctat ccctccaagtggattgccaggcttcgccacatcaagcgactccgccaccggatccgcgag gaagcccactacaccaaccccagcctgccactgatgcagatgcaccccttgggccacccc aaagcccctgctcaggcgccggcagagcctctgcccacgtatgagacaggccagcggaag cgtctcatctcctctgtggatgacttcacggagtttgtgtga

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