Vulpes vulpes (red fox): 112911890
Help
Entry
112911890 CDS
T05911
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00562
Inositol phosphate metabolism
vvp01100
Metabolic pathways
vvp01521
EGFR tyrosine kinase inhibitor resistance
vvp04012
ErbB signaling pathway
vvp04014
Ras signaling pathway
vvp04020
Calcium signaling pathway
vvp04062
Chemokine signaling pathway
vvp04064
NF-kappa B signaling pathway
vvp04066
HIF-1 signaling pathway
vvp04070
Phosphatidylinositol signaling system
vvp04072
Phospholipase D signaling pathway
vvp04360
Axon guidance
vvp04370
VEGF signaling pathway
vvp04380
Osteoclast differentiation
vvp04611
Platelet activation
vvp04625
C-type lectin receptor signaling pathway
vvp04650
Natural killer cell mediated cytotoxicity
vvp04662
B cell receptor signaling pathway
vvp04664
Fc epsilon RI signaling pathway
vvp04666
Fc gamma R-mediated phagocytosis
vvp04670
Leukocyte transendothelial migration
vvp04722
Neurotrophin signaling pathway
vvp04750
Inflammatory mediator regulation of TRP channels
vvp04919
Thyroid hormone signaling pathway
vvp04933
AGE-RAGE signaling pathway in diabetic complications
vvp04935
Growth hormone synthesis, secretion and action
vvp05167
Kaposi sarcoma-associated herpesvirus infection
vvp05169
Epstein-Barr virus infection
vvp05170
Human immunodeficiency virus 1 infection
vvp05171
Coronavirus disease - COVID-19
vvp05200
Pathways in cancer
vvp05205
Proteoglycans in cancer
vvp05206
MicroRNAs in cancer
vvp05214
Glioma
vvp05223
Non-small cell lung cancer
vvp05225
Hepatocellular carcinoma
Module
vvp_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112911890
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112911890
04014 Ras signaling pathway
112911890
04370 VEGF signaling pathway
112911890
04064 NF-kappa B signaling pathway
112911890
04066 HIF-1 signaling pathway
112911890
04020 Calcium signaling pathway
112911890
04070 Phosphatidylinositol signaling system
112911890
04072 Phospholipase D signaling pathway
112911890
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112911890
04625 C-type lectin receptor signaling pathway
112911890
04650 Natural killer cell mediated cytotoxicity
112911890
04662 B cell receptor signaling pathway
112911890
04664 Fc epsilon RI signaling pathway
112911890
04666 Fc gamma R-mediated phagocytosis
112911890
04670 Leukocyte transendothelial migration
112911890
04062 Chemokine signaling pathway
112911890
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
112911890
04919 Thyroid hormone signaling pathway
112911890
09156 Nervous system
04722 Neurotrophin signaling pathway
112911890
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112911890
09158 Development and regeneration
04360 Axon guidance
112911890
04380 Osteoclast differentiation
112911890
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112911890
05206 MicroRNAs in cancer
112911890
05205 Proteoglycans in cancer
112911890
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112911890
05214 Glioma
112911890
05223 Non-small cell lung cancer
112911890
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112911890
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112911890
05171 Coronavirus disease - COVID-19
112911890
05167 Kaposi sarcoma-associated herpesvirus infection
112911890
05169 Epstein-Barr virus infection
112911890
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112911890
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vvp04131
]
112911890
Enzymes [BR:
vvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
112911890
Membrane trafficking [BR:
vvp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
112911890
Endocytosis
Macropinocytosis
Phospholipase C
112911890
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PH
PH_12
PH_14
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
112911890
NCBI-ProteinID:
XP_025844363
UniProt:
A0A3Q7RGE6
LinkDB
All DBs
Position
Unknown
AA seq
867 aa
AA seq
DB search
MTALVHVDSLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFVLSTLSLAADSKEDAN
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVNSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRARMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARV
FKEVFGDQLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWFHKKVEKR
TSAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSTVEGGTMKYF
LTDNVTFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMHLPTKALQCPLFSSRWKGDYGTRIQQYFPSNYVED
ISTVDVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPV
EFATDKVEELFEWFQSIREITWKIDTK
NT seq
2601 nt
NT seq
+upstream
nt +downstream
nt
atgactgccctggtccacgtggacagccttccggaatacgagaagagtcagatcaagaga
gccctagagctgggcacggtgatgacggtgttcagcttccgcaagtccaccccagagcgg
aggaccgtccaggtgatcatggagacgcgccaggtggcctggagcaagacagccgacaag
atcgagggcttcttggatatcatggaaatcaaggaaatccgcccagggaagaactccaag
gattttgagcgtgccaaagcagtccgccagaaggaagagtgctgttttaccatcttgtac
ggcacccagtttgttctgagcacactcagtctggcagctgactctaaagaagatgcgaat
aagtggctctctggcttgaaaatcttacaccaggaagcgatgagtgcatctacacccacc
attattgagagttggctgagaaagcagatttattcagtggaccaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttacccctggtcaactttaaggtgaacagtgcc
aagttcctcaaagataagtttgtggaaattggtgcacacaaagatgagctcagctttgag
cagttccacctgttctataaaaaacttatgtttgagcagcaaaagtcgattcttgatgaa
ttcaaaaaagattcttccgtgttcatcttgggcaacactgaccggccggacgcctctgct
gttcacctgcacgacttccagcgctttctcttacatgagcaacaggagctttgggctcag
gatctgaacaaagtccgtgcgcggatgacaaagtttatcgatgacaccatgagggaaacg
gccgagcccttcttgtttgtcgatgagttcctcacgtatctgttttcgcgggagaacagc
atctgggatgagaagtacgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcttcgcataacacgtacctcactggtgaccagctacggagtgagtca
tccacagaagcgtacatccgttgcctgcggatgggctgtcgctgcattgagttggactgc
tgggacgggcccgacgggaagcccatcatctaccacggctggacacggaccaccaagatc
aagtttgatgacgttgtgcaggccatcaaagaccatgcctttgtcacttcaagcttcccc
gtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgccacatggccagggtg
ttcaaggaggtgtttggcgaccagctgctgacgaagcccacagaggccagtgctgaccag
ctgccctcccccagccagttgcgggagaagatcatcatcaagcataagaagctgggtccc
cgaggggacgtggatgtcaacatggaggacaagaaagatgagcacaagcaacagggtgaa
ctgtatatgtgggattccatcgaccagaaatggactcgacactactgtgccatcgccgat
gccaaactgtctttcagcgatgacattgagcagactgcagaagaggagctgccccaggac
ataccccccacggagctgcattttggggaggagtggttccacaagaaagtagagaagagg
acgagtgccgagaagctgctgcaggaatactgtgcagagaccgggggcaaggatgggact
ttccttgtgcgggagagcaagaccttccccaatgactacaccctgtccttctggcggtcg
ggccgtgtccagcactgccggatccgttccaccgtggaggggggcaccatgaagtacttc
ctgactgacaacgtcacgttcaccagcatctacgccctcatccagcactaccgcgagacc
cacctgcgctgcgccgagttcgagctgcggctcaccgaccctgtgcccaaccccaacccc
cacgagtccaagccgtggtactacgacgggctgagccgtggggaggcagaggacatgcta
atgagggtgccccgggacggcgccttcctgatccggaggcgagaaggtaccgactcctat
gccatcaccttcagggccaggggcaaggtgaagcactgccgcattcaccgggatggccgg
cactttgtgctggggacctctgcctacttcgagagcctcgtggagctagtcagctactac
gaaaagcacgcgctctaccgaaaaatgcgactgcgctaccccgtgacgcctgagctcctg
gagcgctacaatatgcacctgcccacgaaggccctccagtgccctctgttttcatctagg
tggaagggggactatggaaccagaatccagcagtacttcccatccaattacgtcgaggac
atttcaacagtcgacgtggaggagctggagaagcagattattgaagacaatcccttaggg
tctctttgtaggggaatactggatctcaatacctataacgttgtgaaagccccccagggg
aaaaaccagaagccattcgtgtttatcctggagcccaagaagcaaggcgaccccccagta
gagtttgccacggacaaggtggaggagctctttgagtggtttcagagcatccgggagatc
acctggaagatagacaccaag
Vulpes vulpes (red fox): 112912331
Help
Entry
112912331 CDS
T05911
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00562
Inositol phosphate metabolism
vvp01100
Metabolic pathways
vvp01521
EGFR tyrosine kinase inhibitor resistance
vvp04012
ErbB signaling pathway
vvp04014
Ras signaling pathway
vvp04020
Calcium signaling pathway
vvp04062
Chemokine signaling pathway
vvp04064
NF-kappa B signaling pathway
vvp04066
HIF-1 signaling pathway
vvp04070
Phosphatidylinositol signaling system
vvp04072
Phospholipase D signaling pathway
vvp04360
Axon guidance
vvp04370
VEGF signaling pathway
vvp04380
Osteoclast differentiation
vvp04611
Platelet activation
vvp04625
C-type lectin receptor signaling pathway
vvp04650
Natural killer cell mediated cytotoxicity
vvp04662
B cell receptor signaling pathway
vvp04664
Fc epsilon RI signaling pathway
vvp04666
Fc gamma R-mediated phagocytosis
vvp04670
Leukocyte transendothelial migration
vvp04722
Neurotrophin signaling pathway
vvp04750
Inflammatory mediator regulation of TRP channels
vvp04919
Thyroid hormone signaling pathway
vvp04933
AGE-RAGE signaling pathway in diabetic complications
vvp04935
Growth hormone synthesis, secretion and action
vvp05167
Kaposi sarcoma-associated herpesvirus infection
vvp05169
Epstein-Barr virus infection
vvp05170
Human immunodeficiency virus 1 infection
vvp05171
Coronavirus disease - COVID-19
vvp05200
Pathways in cancer
vvp05205
Proteoglycans in cancer
vvp05206
MicroRNAs in cancer
vvp05214
Glioma
vvp05223
Non-small cell lung cancer
vvp05225
Hepatocellular carcinoma
Module
vvp_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112912331
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112912331
04014 Ras signaling pathway
112912331
04370 VEGF signaling pathway
112912331
04064 NF-kappa B signaling pathway
112912331
04066 HIF-1 signaling pathway
112912331
04020 Calcium signaling pathway
112912331
04070 Phosphatidylinositol signaling system
112912331
04072 Phospholipase D signaling pathway
112912331
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112912331
04625 C-type lectin receptor signaling pathway
112912331
04650 Natural killer cell mediated cytotoxicity
112912331
04662 B cell receptor signaling pathway
112912331
04664 Fc epsilon RI signaling pathway
112912331
04666 Fc gamma R-mediated phagocytosis
112912331
04670 Leukocyte transendothelial migration
112912331
04062 Chemokine signaling pathway
112912331
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
112912331
04919 Thyroid hormone signaling pathway
112912331
09156 Nervous system
04722 Neurotrophin signaling pathway
112912331
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112912331
09158 Development and regeneration
04360 Axon guidance
112912331
04380 Osteoclast differentiation
112912331
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112912331
05206 MicroRNAs in cancer
112912331
05205 Proteoglycans in cancer
112912331
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112912331
05214 Glioma
112912331
05223 Non-small cell lung cancer
112912331
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112912331
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112912331
05171 Coronavirus disease - COVID-19
112912331
05167 Kaposi sarcoma-associated herpesvirus infection
112912331
05169 Epstein-Barr virus infection
112912331
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112912331
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vvp04131
]
112912331
Enzymes [BR:
vvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
112912331
Membrane trafficking [BR:
vvp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
112912331
Endocytosis
Macropinocytosis
Phospholipase C
112912331
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-Y
SH2
C2
SH3_1
SH3_9
SH3_2
PH
Motif
Other DBs
NCBI-GeneID:
112912331
NCBI-ProteinID:
XP_025844837
UniProt:
A0A3Q7RGJ6
LinkDB
All DBs
Position
Unknown
AA seq
681 aa
AA seq
DB search
HCRIRSTVEGGTMKYFLTDNVTFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESK
PWYYDGLSRGEAEDMLMRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVL
GTSAYFESLVELVSYYEKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSE
INPSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPWGWWKGDYGTRIQQYFPSNYV
EDISTVDVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDP
PVEFATDKVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTK
DNLENPDFREIRSFVETKADSVVRQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWL
CGSQMVALNFQTPDKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLS
VKVLGARHLPKLGRSIACPFVEVEICGAEYDNNKFKTTVVNDNGLSPVWAPTQEKVTFEI
YDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFC
EMQPVLESEEELYSSCRQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQL
YQEKCNRRLREKRVSNSRFYS
NT seq
2046 nt
NT seq
+upstream
nt +downstream
nt
cactgccggatccgttccaccgtggaggggggcaccatgaagtacttcctgactgacaac
gtcacgttcaccagcatctacgccctcatccagcactaccgcgagacccacctgcgctgc
gccgagttcgagctgcggctcaccgaccctgtgcccaaccccaacccccacgagtccaag
ccgtggtactacgacgggctgagccgtggggaggcagaggacatgctaatgagggtgccc
cgggacggcgccttcctgatccggaggcgagaaggtaccgactcctacgccatcaccttc
agggccaggggcaaggtgaagcactgccgcattcaccgggatggccggcactttgtgctg
gggacctctgcctacttcgagagcctcgtggagctagtcagctactacgaaaagcacgcg
ctctaccgaaaaatgcgactgcgctaccccgtgacgcctgagctcctggagcgctacaat
atggaaagagatataaactccctctatgacgtcagcagaatgtatgtggatcccagtgag
atcaatccttctatgcctcagaggaccgtgaaagctctgtatgactacaaagccaagcga
agcgatgagctgagtttctgccgtggggccctcattcacaacgtctcgaaggagccctgg
ggctggtggaagggggactatggaaccagaatccagcagtacttcccatccaattacgtc
gaggacatttcaacagtcgacgtggaggagctggagaagcagattattgaagacaatccc
ttagggtctctttgtaggggaatactggatctcaatacctataacgttgtgaaagccccc
caggggaaaaaccagaagccattcgtgtttatcctggagcccaagaagcaaggcgacccc
ccagtagagtttgccacggacaaggtggaggagctctttgagtggtttcagagcatccgg
gagatcacctggaagatagacaccaaggagaacaacatgaagtactgggagaagaaccag
tccattgccatcgagctctcggacctggtcgtctactgcaagccaaccagcaagaccaag
gacaatttagaaaaccctgacttccgagaaatccggtcctttgtggagacaaaggcagac
agtgttgtcagacagaaacctgttgacctcctgaagtacaatcagaagggcctgacccgt
gtttacccgaagggacagagggtggactcctccaactacgacccctttcgcctctggctg
tgcggctcccagatggtggcactcaatttccagactccagacaagtatatgcagatgaat
cacgccttgttctcactcaatgggcgaacgggctacgtcctacagcctgagagcatgagg
acggagaagtatgaccccatgccacctgagtcccagaggaagatcctgatgactctgtca
gtcaaggttcttggggctcgccatctccccaaacttggacgaagtatcgcgtgtcccttt
gtggaggtggaaatttgtggagctgaatatgacaacaacaagtttaagacaacagtcgtg
aatgacaatggcctaagccctgtttgggctccaacacaggagaaagtgacctttgaaatt
tacgaccccaacctggcgtttctgcgctttgtggtctacgaggaagatatgttcagtgac
cccaatttccttgctcacgccacttaccccatcaaaggaatcaaatcaggattcagatct
gttcctctgaagaacgggtacagtgaagacattgagctggcttccctcctggttttctgt
gagatgcagccagtcctggagagcgaagaggaactttattcctcctgtcgccagctgcga
aggcggcaggaagagctcaacaatcagctctttctgtacgacacacaccagaacttgcgc
aacgccaaccgggatgccctcgttaaagagttcaacgtcaacgagaaccagctccagctg
taccaggagaagtgcaaccggaggttgagagagaagcgagtcagcaacagcaggttttac
tcctag
Vulpes vulpes (red fox): 112928123
Help
Entry
112928123 CDS
T05911
Gene name
PLCG1
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
KO
K01116
phosphatidylinositol phospholipase C, gamma-1 [EC:
3.1.4.11
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00562
Inositol phosphate metabolism
vvp01100
Metabolic pathways
vvp01521
EGFR tyrosine kinase inhibitor resistance
vvp04012
ErbB signaling pathway
vvp04014
Ras signaling pathway
vvp04015
Rap1 signaling pathway
vvp04020
Calcium signaling pathway
vvp04062
Chemokine signaling pathway
vvp04064
NF-kappa B signaling pathway
vvp04066
HIF-1 signaling pathway
vvp04070
Phosphatidylinositol signaling system
vvp04072
Phospholipase D signaling pathway
vvp04360
Axon guidance
vvp04370
VEGF signaling pathway
vvp04650
Natural killer cell mediated cytotoxicity
vvp04658
Th1 and Th2 cell differentiation
vvp04659
Th17 cell differentiation
vvp04660
T cell receptor signaling pathway
vvp04664
Fc epsilon RI signaling pathway
vvp04666
Fc gamma R-mediated phagocytosis
vvp04670
Leukocyte transendothelial migration
vvp04722
Neurotrophin signaling pathway
vvp04750
Inflammatory mediator regulation of TRP channels
vvp04919
Thyroid hormone signaling pathway
vvp04933
AGE-RAGE signaling pathway in diabetic complications
vvp04935
Growth hormone synthesis, secretion and action
vvp05012
Parkinson disease
vvp05022
Pathways of neurodegeneration - multiple diseases
vvp05135
Yersinia infection
vvp05167
Kaposi sarcoma-associated herpesvirus infection
vvp05170
Human immunodeficiency virus 1 infection
vvp05171
Coronavirus disease - COVID-19
vvp05200
Pathways in cancer
vvp05205
Proteoglycans in cancer
vvp05206
MicroRNAs in cancer
vvp05214
Glioma
vvp05223
Non-small cell lung cancer
vvp05225
Hepatocellular carcinoma
vvp05231
Choline metabolism in cancer
vvp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Module
vvp_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
112928123 (PLCG1)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
112928123 (PLCG1)
04014 Ras signaling pathway
112928123 (PLCG1)
04015 Rap1 signaling pathway
112928123 (PLCG1)
04370 VEGF signaling pathway
112928123 (PLCG1)
04064 NF-kappa B signaling pathway
112928123 (PLCG1)
04066 HIF-1 signaling pathway
112928123 (PLCG1)
04020 Calcium signaling pathway
112928123 (PLCG1)
04070 Phosphatidylinositol signaling system
112928123 (PLCG1)
04072 Phospholipase D signaling pathway
112928123 (PLCG1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
112928123 (PLCG1)
04660 T cell receptor signaling pathway
112928123 (PLCG1)
04658 Th1 and Th2 cell differentiation
112928123 (PLCG1)
04659 Th17 cell differentiation
112928123 (PLCG1)
04664 Fc epsilon RI signaling pathway
112928123 (PLCG1)
04666 Fc gamma R-mediated phagocytosis
112928123 (PLCG1)
04670 Leukocyte transendothelial migration
112928123 (PLCG1)
04062 Chemokine signaling pathway
112928123 (PLCG1)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
112928123 (PLCG1)
04919 Thyroid hormone signaling pathway
112928123 (PLCG1)
09156 Nervous system
04722 Neurotrophin signaling pathway
112928123 (PLCG1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
112928123 (PLCG1)
09158 Development and regeneration
04360 Axon guidance
112928123 (PLCG1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112928123 (PLCG1)
05206 MicroRNAs in cancer
112928123 (PLCG1)
05205 Proteoglycans in cancer
112928123 (PLCG1)
05231 Choline metabolism in cancer
112928123 (PLCG1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112928123 (PLCG1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
112928123 (PLCG1)
05214 Glioma
112928123 (PLCG1)
05223 Non-small cell lung cancer
112928123 (PLCG1)
09164 Neurodegenerative disease
05012 Parkinson disease
112928123 (PLCG1)
05022 Pathways of neurodegeneration - multiple diseases
112928123 (PLCG1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112928123 (PLCG1)
09171 Infectious disease: bacterial
05135 Yersinia infection
112928123 (PLCG1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
112928123 (PLCG1)
05171 Coronavirus disease - COVID-19
112928123 (PLCG1)
05167 Kaposi sarcoma-associated herpesvirus infection
112928123 (PLCG1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112928123 (PLCG1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
vvp04131
]
112928123 (PLCG1)
Enzymes [BR:
vvp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
112928123 (PLCG1)
Membrane trafficking [BR:
vvp04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
112928123 (PLCG1)
Endocytosis
Macropinocytosis
Phospholipase C
112928123 (PLCG1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
SH3_1
C2
PH
SH3_9
SH3_2
PH_12
GDPD
PH_9
Motif
Other DBs
NCBI-GeneID:
112928123
NCBI-ProteinID:
XP_025865442
UniProt:
A0A3Q7TW26
LinkDB
All DBs
Position
Unknown
AA seq
1282 aa
AA seq
DB search
MTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQ
EDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAATPLQIE
RWLRKQFYSVDRNREDRISAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSSDITYGQFA
QLYRSLMYSAQKTMDLPFLEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQ
EFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSS
HNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVL
HTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQ
LKRKILIKHKKLAEGSAYEEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTS
SKIYYSEETSSDQGNEDEEEPKEASGSTELHSSEKWFHGKLGAGRDGRHIAERLLTEYCI
ETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGAPKFFLTDNLVFDSLYD
LITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR
KRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRY
PINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQRDDELTFTK
SAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRG
VLDVPACQIAIRPEGKNNRLFVFSISMASVAHWSLDVAADSQEELQDWVKKIREVAQTAD
ARLTEGKMMERRKKIALELSELVVYCRPVPFDEDKIGTERACYRDMSSFPETKAEKYVNK
AKGKKFLQYNRLQLSRIYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALF
MAGGHCGYVLQPSTMRDEAFDPFDKSSLRGLEPYAICIEVLGARHLPKNGRGIVCPFVEI
EVAGAEYDSIKQKTEFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLA
QATFPVKGLKTGYRAVPLKNNYSEDLELASLLVKIDVFPAKVRVVGVAGSLSRPREVLTP
RALLLLKQENGDLSPFGMSLRERGSDASGQLFHGRAREGSFEARYQQPFEDFRISQEHLA
DHFDSRERRAPRRTRVNGDNRL
NT seq
3849 nt
NT seq
+upstream
nt +downstream
nt
atgactttgttctactccaagaagtcgcagcggccggagcggaagaccttccaggtcaag
ctggagacgcggcagatcacgtggagccgtggcgccgacaagatcgagggggccattgac
attcgagaaatcaaggagatccgcccagggaagacctcacgggattttgatcgctaccaa
gaggaccctgctttccgaccagaccagtcacactgcttcgtcatcctgtatgggatggaa
ttccgcctgaagactctgagcctgcaagctacatctgaggatgaagtgaacatgtggatc
aagggtttaacttggctgatggaggatactttgcaggcagccacacctctgcagattgag
aggtggctgcggaagcagttctactcagtggatcggaatcgtgaggatcgtatatcagcc
aaggacttgaagaacatgctgtcccaggtcaactaccgggttcccaacatgcgcttcctc
cgagagcgtctgacggacctggagcagcgcagcagtgacatcacctacgggcagtttgct
caactgtaccgcagcctcatgtacagcgcccagaagacgatggacctccccttcttggaa
gccagtgccctgagggcaggggagcgcccggagctctgtcgtgtgtcccttcctgagttc
cagcagttcctcctcgagtaccagggggagctgtgggctgttgaccggcttcaggtgcag
gagttcatgctcagcttccttcgagatcctttgcgagaaattgaagagccttacttcttc
ctggacgagtttgtcaccttcttgttctccaaagagaacagcgtgtggaattcacagctg
gatgcagtgtgcccagacaccatgaacaaccctctgtcccactactggatctcctcctcc
cacaacacgtacctgactggggaccagttctccagtgagtcctccctggaagcctatgct
cgctgcctgcggatgggctgtcgctgcattgagttggactgctgggatggcccagatggg
atgccagtcatttaccatgggcacacccttaccaccaagatcaagttctcagatgttcta
cataccatcaaggagcatgccttcgtggcttcagagtatccggtcatcctgtccatcgag
gaccactgcagcatcgcccagcagagaaacatggcgcagtacttcaagaaggtgcttggg
gacacactcctcaccaagcctgtggacatcgctgctgacgggctcccctcacccaaccag
ctcaagaggaagatcctcatcaagcacaagaagctggcagagggcagtgcctacgaagag
gtgcctacgtcagtgatgtactctgagaacgatatcagcaactccatcaagaatggcatc
ctctacctggaggacccggtgaaccatgagtggtacccccactacttcgttctgaccagc
agcaagatctactactctgaggagaccagcagtgaccagggcaatgaggatgaggaggaa
cccaaggaggccagtggcagcacagagctgcactccagtgagaagtggttccacgggaag
cttggggcaggacgggatggacgacacattgccgagcgcctgctcaccgagtattgcatt
gagaccggggcccctgatggctccttcctcgtgcgggagagcgagaccttcgtgggcgac
tataccctctctttctggaggaacgggaaagtccagcactgtcggatccattcccggcag
gatgctggggcccccaagttcttcttgacagacaacctggtctttgattcgctctatgac
ctcatcacgcactaccagcaagtgcccctgcgctgcaacgaatttgagatgcgcctttca
gagccggtcccgcagaccaatgcccacgagagcaaagagtggtaccacgccagcctgacc
agagctcaggccgagcacatgctgatgcgtgttccccgggatggggccttcctggtgagg
aaacggaatgagcccaactcctatgccatctctttccgggccgagggcaagatcaaacat
tgccgcgtccagcaggagggccagactgtgatgctgggcaactctgagtttgacagcctc
gtggacctcatcagctactatgagaagcacccgctataccgcaaaatgaagctgcgctat
cccatcaatgaggaagcgctggagaagataggcacagctgagcctgactatggagccctg
tatgagggacgcaaccctggcttctatgtggaggcaaatcctatgccaacttttaagtgt
gccgtcaaagccctctttgactacaaggctcagagggatgacgagctgacattcacgaag
agtgccatcattcagaatgtggagaagcaagaaggcggctggtggcggggggactacggg
gggaaaaagcagctctggttcccgtcaaactacgtagaagagatggtcagccctgcagcc
ctggagcctgagagggagcacttggatgagaacagccccctgggggacttgctccgtggg
gtcttggatgtgccagcctgtcagattgccatccgtcctgagggcaagaacaaccggctc
ttcgtcttctccatcagcatggcttcagtggcacactggtccttggatgtcgctgctgat
tcacaggaagagctgcaggactgggtgaagaagatccgagaagtggcccagacggcagac
gccaggctcacggaggggaagatgatggagcgcaggaagaagatcgccctggagctctct
gagctggttgtctactgcaggccggttcccttcgatgaagacaagattggcacagaacgt
gcgtgctaccgggacatgtcatcctttccggaaaccaaggctgagaaatatgtgaacaag
gccaaaggcaagaagttcctccagtacaaccggctgcagctctcgcgcatctaccccaag
ggccagcggctggactcctccaattatgaccccctgcccatgtggatctgtggcagtcag
ctcgtagccctcaacttccagaccccagacaagcccatgcagatgaaccaggccctcttc
atggctggcggccactgcggctacgtgctgcagccgagcaccatgcgggacgaggccttt
gatccctttgacaagagcagcctccgaggcctggaaccatatgccatctgcattgaggtg
ctgggggctcggcacctgccaaagaacggccgaggcatcgtgtgtcctttcgtggagatt
gaagtggccggagcagagtacgacagcatcaagcagaagacagagttcgtggtggacaat
ggactgaaccctgtgtggcctgccaagcccttccacttccagatcagtaacccggaattc
gcctttttgcgctttgtggtgtatgaggaagacatgtttagtgaccagaacttcctggct
caggctacattcccggtgaaaggcctgaagacaggatacagagctgtgcctttgaagaac
aactacagtgaggacctagagctggcctccctgctcgtcaagatcgatgtgttccctgcc
aaggtaagggtggtgggggtggcggggagcctctccaggccccgggaggtgctgacccct
cgtgcactgctgttgttgaagcaggagaatggggacctcagtcccttcgggatgtctctt
cgggagcggggctctgatgcctcaggccagctgttccatggccgggcccgtgaaggttcc
tttgaggcccgctaccagcagccatttgaggactttcgtatctcccaggagcacctggca
gaccattttgacagtcgggaacggagggccccacggaggacacgggtcaacggagacaac
cgcctctag
DBGET
integrated database retrieval system
