Vulpes vulpes (red fox): 112916218
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Entry
112916218 CDS
T05911
Gene name
NOS3
Definition
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
vvp
Vulpes vulpes (red fox)
Pathway
vvp00220
Arginine biosynthesis
vvp00330
Arginine and proline metabolism
vvp01100
Metabolic pathways
vvp04020
Calcium signaling pathway
vvp04022
cGMP-PKG signaling pathway
vvp04066
HIF-1 signaling pathway
vvp04071
Sphingolipid signaling pathway
vvp04151
PI3K-Akt signaling pathway
vvp04370
VEGF signaling pathway
vvp04371
Apelin signaling pathway
vvp04611
Platelet activation
vvp04915
Estrogen signaling pathway
vvp04921
Oxytocin signaling pathway
vvp04926
Relaxin signaling pathway
vvp04931
Insulin resistance
vvp04933
AGE-RAGE signaling pathway in diabetic complications
vvp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
vvp00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
112916218 (NOS3)
00330 Arginine and proline metabolism
112916218 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
112916218 (NOS3)
04371 Apelin signaling pathway
112916218 (NOS3)
04066 HIF-1 signaling pathway
112916218 (NOS3)
04020 Calcium signaling pathway
112916218 (NOS3)
04071 Sphingolipid signaling pathway
112916218 (NOS3)
04022 cGMP-PKG signaling pathway
112916218 (NOS3)
04151 PI3K-Akt signaling pathway
112916218 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
112916218 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
112916218 (NOS3)
04921 Oxytocin signaling pathway
112916218 (NOS3)
04926 Relaxin signaling pathway
112916218 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
112916218 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
112916218 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
112916218 (NOS3)
Enzymes [BR:
vvp01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
112916218 (NOS3)
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Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
HTH_15
Motif
Other DBs
NCBI-GeneID:
112916218
NCBI-ProteinID:
XP_025849586
UniProt:
A0A3Q7S4F7
LinkDB
All DBs
Position
Unknown
AA seq
1213 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTSEPSRAPALAPPPSPPPAPDHSSPP
LTRPPDGPKFPRVKNWEVGSITYDTLSAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQDPA
PPEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRASGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDE
PPELFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQTD
PWKGSASKGAGVTRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL
GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKQSSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKA
AARDIFSPKRTWKRQRYRLSAQAEGLQLLPGLIHVHRRKMVQATVLAVENLQSSKSTRAT
ILVRLDTGSQEALQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPD
LPCTPSPGGPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESSEQQEL
ESLSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHP
GEIHLTVAVLAYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCI
LVGPGTGIAPFRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVF
GRVLTAFSREPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRI
LATEGDMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVP
WAFDPPGPDTAGP
NT seq
3642 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcccgggcccccttgtggcctggggctgggc
ctgggcctggggctatgtggcaagcagggccctgcctccccgacctcagagcccagccgg
gcaccggccctggcgcccccaccctcacccccaccagcaccagaccacagcagccccccg
ctcacccggcctccagatgggcccaagttccctcgtgtgaagaactgggaggtggggagc
atcacttatgacaccttgagtgcccagtcacagcaggatgggccctgcaccccgagacgc
tgtctgggctctctggtatttccacggaaactgcagagccggccctcccaggaccctgca
ccccctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagtggctcccaggcccatgagcagaggcttcaagaggtggaagctgaggtagca
gccacaggcacctatcagcttcgggaaagcgagctggtgttcggggccaagcaggcctgg
cgaaacgctccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcc
cgggattgcagttctgcccaggagatgttcacctacatctgcaaccacatcaagtatgcc
accaaccggggcaacctccgctcggccatcacagtgttcccccagcgtgcctcaggccgc
ggagacttccgaatttggaacagccagctggtgcgctatgcgggctacagacagcaggat
ggctcagtgcggggggacccagccaacgtggagatcactgagctctgcatccagcacggc
tggactccaggaaacggccgctttgatgtgctgcccctactgctccaggccccagatgag
cccccagaactctttgctctgccccccgagctggttctcgaggtgcccctggagcacccc
acgctggagtggtttgcagccctgggcctgcgctggtatgccctcccagcggtgagcaac
atgctgctggaaattggggggctggagttccctgcggcccccttcagcggctggtacatg
agcactgagattggcacgcggaacctgtgtgaccctcatcgatacaacatcctggaggat
gtggctgtctgcatggacttggataccaggaccacctcatccctgtggaaagacaaggca
gcagtggaaatcaacttggctgtgctgcacagttaccagctggccaaagtgaccatcgtg
gaccaccatgctgccacagcctccttcatgaagcacctggagaacgagcagaaggccagg
gggggttgccctgctgactgggcctggatcgtgccccccatctctggcagcctcacccct
gttttccatcaggagatggtcaactatgtcctgtccccggccttccgctatcagacagac
ccgtggaaggggagtgcatccaagggtgccggcgtcaccaggaagaaaacctttaaggaa
gtggccaatgcggtgaagatctctgcctcactcatgggcactgtgatggcaaagcgagtg
aaggcgacaatcctctatggctccgagactggccgggcccagagctatgcacagcagctg
gggagactcttccggaaggctttcgacccccgggtcctgtgcatggatgagtatgacgtg
gtgtcccttgagcatgagacgctggtgttggtggtgaccagcacatttgggaatggtgat
cccccagagaatggagagagttttgcggcggccctgatggagatgtcgggtccctacaac
agctcccctcggccagaacagcacaagagttacaaaatccgcttcaacagtgtctcctgc
tcagacccactggtgtcctcctggaggcggaagagaaagcagtccagtaacacagacagt
gctggggcactgggtaccctcaggttctgtgtgttcgggctgggctcccgggcatacccc
cacttttgtgcctttgctcgtgcggtggacacacggctggaagagctgggtggggagcgg
ctgctgcagctgggccaaggagatgagctgtgtggccaggaggaggccttccgaggctgg
gcccaggccgccttccaggcctcctgtgagaccttctgcgtgggagaggatgccaaggct
gccgcccgggacatattcagccccaaacggacctggaagcgccagaggtaccggctgagc
gcccaggctgagggcctccagctgctgccaggactgatccatgtgcacaggaggaagatg
gtccaggctactgtcctcgcggtggaaaacctgcaaagcagcaagtccacccgggccacg
atcctggtgcgcctggacactggaagccaggaggcgctgcagtaccagccaggggaccac
attggcatctgcccgcccaaccggcctggccttgtggaggcgctgctgagccgggtggag
gatccaccgccaccaggagagccagtggcagtggagcagctggagaagggcagccctgat
ctcccctgtacaccatcaccaggtggcccaccccccagctgggttcgggaccctcgcctg
cccccatgcacactgcgccaggctctcaccttcttcctggacatcacttccccgcccagc
cctcaactccttcgactgctcagcaccctggctgaagagtccagtgaacagcaggagctt
gagagcctcagccaggacccccggcgctatgaggaatggaagtggttccgctgccccaca
ctgctggaggtactggaacagttcccatcggtggcactgcccgcccccctgctcctcacc
cagctgcccctgctccagccccggtactactcggtcagctcagcacccagtgcccaccca
ggagagatccacctcacagtagctgtgctggcatacaggacacaggatggactgggcccc
cttcattatggagtctgctccacatggctaagccaacttaaggccggagatcctgtaccc
tgcttcatcaggggggctccctccttccggctgccacctgatcccagtctgccttgcatc
ctagtgggtcctggtacgggtattgccccctttcggggtttctggcaggagcggctgcac
gacattgacagcaaagggctgcagcccgcccccatgactctggtgttcggctgccgatgc
tcccagctcgaccacctttaccgcgacgaggtgcaggatgcccagcagcgcggagttttt
gggcgcgtcctcaccgccttctcccgggagcccgacagccctaagacgtacgtgcaggac
atcctgcggacggagctggctgctgaggtgcaccgcgtgctgtgcctcgagcggggccac
atgtttgtgtgcggcgacgtcaccatggcaaccagcgtcctgcagacggtgcagcgaatc
ctagcgacggagggcgacatggagctggacgaggccggtgacgtcatcggcgtgctgcgg
gatcagcaacgctatcacgaggacattttcgggctcacactgcgcacccaggaggtgacg
agccgcatacgcacccagagcttctccttgcaggagcggcatctgcggggcgcggtgccc
tgggcgttcgacccgcccggcccagacaccgccggcccctga
DBGET
integrated database retrieval system
