KEGG   Vulpes vulpes (red fox): 112917213
Entry
112917213         CDS       T05911                                 

Gene name
KRAS
Definition
(RefSeq) GTPase KRas isoform X1
  KO
K07827  GTPase KRas
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp01521  EGFR tyrosine kinase inhibitor resistance
vvp01522  Endocrine resistance
vvp04010  MAPK signaling pathway
vvp04012  ErbB signaling pathway
vvp04014  Ras signaling pathway
vvp04015  Rap1 signaling pathway
vvp04062  Chemokine signaling pathway
vvp04068  FoxO signaling pathway
vvp04071  Sphingolipid signaling pathway
vvp04072  Phospholipase D signaling pathway
vvp04137  Mitophagy - animal
vvp04140  Autophagy - animal
vvp04150  mTOR signaling pathway
vvp04151  PI3K-Akt signaling pathway
vvp04210  Apoptosis
vvp04211  Longevity regulating pathway
vvp04213  Longevity regulating pathway - multiple species
vvp04218  Cellular senescence
vvp04360  Axon guidance
vvp04370  VEGF signaling pathway
vvp04371  Apelin signaling pathway
vvp04540  Gap junction
vvp04550  Signaling pathways regulating pluripotency of stem cells
vvp04625  C-type lectin receptor signaling pathway
vvp04650  Natural killer cell mediated cytotoxicity
vvp04660  T cell receptor signaling pathway
vvp04662  B cell receptor signaling pathway
vvp04664  Fc epsilon RI signaling pathway
vvp04714  Thermogenesis
vvp04720  Long-term potentiation
vvp04722  Neurotrophin signaling pathway
vvp04725  Cholinergic synapse
vvp04726  Serotonergic synapse
vvp04730  Long-term depression
vvp04810  Regulation of actin cytoskeleton
vvp04910  Insulin signaling pathway
vvp04912  GnRH signaling pathway
vvp04914  Progesterone-mediated oocyte maturation
vvp04915  Estrogen signaling pathway
vvp04916  Melanogenesis
vvp04917  Prolactin signaling pathway
vvp04919  Thyroid hormone signaling pathway
vvp04921  Oxytocin signaling pathway
vvp04926  Relaxin signaling pathway
vvp04929  GnRH secretion
vvp04933  AGE-RAGE signaling pathway in diabetic complications
vvp04935  Growth hormone synthesis, secretion and action
vvp04960  Aldosterone-regulated sodium reabsorption
vvp05010  Alzheimer disease
vvp05022  Pathways of neurodegeneration - multiple diseases
vvp05034  Alcoholism
vvp05160  Hepatitis C
vvp05161  Hepatitis B
vvp05163  Human cytomegalovirus infection
vvp05165  Human papillomavirus infection
vvp05166  Human T-cell leukemia virus 1 infection
vvp05167  Kaposi sarcoma-associated herpesvirus infection
vvp05170  Human immunodeficiency virus 1 infection
vvp05200  Pathways in cancer
vvp05203  Viral carcinogenesis
vvp05205  Proteoglycans in cancer
vvp05206  MicroRNAs in cancer
vvp05210  Colorectal cancer
vvp05211  Renal cell carcinoma
vvp05212  Pancreatic cancer
vvp05213  Endometrial cancer
vvp05214  Glioma
vvp05215  Prostate cancer
vvp05216  Thyroid cancer
vvp05218  Melanoma
vvp05219  Bladder cancer
vvp05220  Chronic myeloid leukemia
vvp05221  Acute myeloid leukemia
vvp05223  Non-small cell lung cancer
vvp05224  Breast cancer
vvp05225  Hepatocellular carcinoma
vvp05226  Gastric cancer
vvp05230  Central carbon metabolism in cancer
vvp05231  Choline metabolism in cancer
vvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112917213 (KRAS)
   04012 ErbB signaling pathway
    112917213 (KRAS)
   04014 Ras signaling pathway
    112917213 (KRAS)
   04015 Rap1 signaling pathway
    112917213 (KRAS)
   04370 VEGF signaling pathway
    112917213 (KRAS)
   04371 Apelin signaling pathway
    112917213 (KRAS)
   04068 FoxO signaling pathway
    112917213 (KRAS)
   04072 Phospholipase D signaling pathway
    112917213 (KRAS)
   04071 Sphingolipid signaling pathway
    112917213 (KRAS)
   04151 PI3K-Akt signaling pathway
    112917213 (KRAS)
   04150 mTOR signaling pathway
    112917213 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    112917213 (KRAS)
   04137 Mitophagy - animal
    112917213 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    112917213 (KRAS)
   04218 Cellular senescence
    112917213 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    112917213 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    112917213 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    112917213 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    112917213 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    112917213 (KRAS)
   04660 T cell receptor signaling pathway
    112917213 (KRAS)
   04662 B cell receptor signaling pathway
    112917213 (KRAS)
   04664 Fc epsilon RI signaling pathway
    112917213 (KRAS)
   04062 Chemokine signaling pathway
    112917213 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    112917213 (KRAS)
   04929 GnRH secretion
    112917213 (KRAS)
   04912 GnRH signaling pathway
    112917213 (KRAS)
   04915 Estrogen signaling pathway
    112917213 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    112917213 (KRAS)
   04917 Prolactin signaling pathway
    112917213 (KRAS)
   04921 Oxytocin signaling pathway
    112917213 (KRAS)
   04926 Relaxin signaling pathway
    112917213 (KRAS)
   04935 Growth hormone synthesis, secretion and action
    112917213 (KRAS)
   04919 Thyroid hormone signaling pathway
    112917213 (KRAS)
   04916 Melanogenesis
    112917213 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    112917213 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    112917213 (KRAS)
   04726 Serotonergic synapse
    112917213 (KRAS)
   04720 Long-term potentiation
    112917213 (KRAS)
   04730 Long-term depression
    112917213 (KRAS)
   04722 Neurotrophin signaling pathway
    112917213 (KRAS)
  09158 Development and regeneration
   04360 Axon guidance
    112917213 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    112917213 (KRAS)
   04213 Longevity regulating pathway - multiple species
    112917213 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    112917213 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112917213 (KRAS)
   05206 MicroRNAs in cancer
    112917213 (KRAS)
   05205 Proteoglycans in cancer
    112917213 (KRAS)
   05203 Viral carcinogenesis
    112917213 (KRAS)
   05230 Central carbon metabolism in cancer
    112917213 (KRAS)
   05231 Choline metabolism in cancer
    112917213 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112917213 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    112917213 (KRAS)
   05212 Pancreatic cancer
    112917213 (KRAS)
   05225 Hepatocellular carcinoma
    112917213 (KRAS)
   05226 Gastric cancer
    112917213 (KRAS)
   05214 Glioma
    112917213 (KRAS)
   05216 Thyroid cancer
    112917213 (KRAS)
   05221 Acute myeloid leukemia
    112917213 (KRAS)
   05220 Chronic myeloid leukemia
    112917213 (KRAS)
   05218 Melanoma
    112917213 (KRAS)
   05211 Renal cell carcinoma
    112917213 (KRAS)
   05219 Bladder cancer
    112917213 (KRAS)
   05215 Prostate cancer
    112917213 (KRAS)
   05213 Endometrial cancer
    112917213 (KRAS)
   05224 Breast cancer
    112917213 (KRAS)
   05223 Non-small cell lung cancer
    112917213 (KRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112917213 (KRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    112917213 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    112917213 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    112917213 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112917213 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    112917213 (KRAS)
   05161 Hepatitis B
    112917213 (KRAS)
   05160 Hepatitis C
    112917213 (KRAS)
   05163 Human cytomegalovirus infection
    112917213 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112917213 (KRAS)
   05165 Human papillomavirus infection
    112917213 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112917213 (KRAS)
   01522 Endocrine resistance
    112917213 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vvp04131]
    112917213 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:vvp04031]
    112917213 (KRAS)
Membrane trafficking [BR:vvp04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    112917213 (KRAS)
GTP-binding proteins [BR:vvp04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    112917213 (KRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin NPR1_interact AAA_25
Other DBs
NCBI-GeneID: 112917213
NCBI-ProteinID: XP_025850869
UniProt: A0A3Q7RZ67
LinkDB
Position
Unknown
AA seq 188 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCIIM
NT seq 567 nt   +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacaatagaggattcctac
aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt
gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

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